Abstract：
PURPOSE:We conducted a systematic review and meta-analysis of randomized and observational studies to evaluate the associations between QRS duration (QRSd) at baseline or in follow-up and outcomes with cardiac resynchronization therapy (CRT). METHODS:We searched online databases to December 2010 and included 6 randomized controlled trials (RCTs) and 38 observational studies. Outcomes included clinical/functional response, left ventricular (LV) remodeling, hospitalizations and mortality. RESULTS:In RCTs, a benefit of CRT was evident only in patients with QRSd >150ms. In observational studies, those meeting either clinical or remodeling CRT response definitions had both wider pooled baseline QRSd and significantly more QRS narrowing with CRT than non-responders. CONCLUSIONS:RCTs demonstrate that benefit with CRT appears restricted to those with baseline QRSd wider than 150ms. Both wider baseline QRS and more QRS narrowing are associated with CRT response in observational studies. Electrocardiographic QRSd plays an important role in CRT patient selection and follow-up.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Bryant AR,Wilton SB,Lai MP,Exner DVdoi
10.1016/j.jelectrocard.2012.12.003subject
Has Abstractpub_date
2013-03-01 00:00:00pages
147-55issue
2eissn
0022-0736issn
1532-8430pii
S0022-0736(12)00536-5journal_volume
46pub_type
杂志文章,meta分析,评审abstract：:The electrocardiogram (ECG) is a relatively insensitive tool for the detection of right ventricular hypertrophy (RVH), but some criteria have high specificity. The recommended ECG screening criteria for RVH are not sufficiently sensitive or specific for screening for mild RVH in adults without clinical cardiovascular ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2017.09.004
更新日期：2018-01-01 00:00:00
abstract：:Electrocardiographic estimation of myocardial injury has, in some studies, correlated poorly with the extent of nuclear perfusion defects at rest and with changes in the left ventricular ejection fraction after acute reperfusion therapy. The authors investigated 16 patients with fatty acid scintigraphy and with the Se...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(05)80256-0
更新日期：1995-07-01 00:00:00
abstract：:We have developed a computer program which simulates a paced cardiac rhythm strip, graphically generating the electrocardiogram (ECG) on a color monitor. Any pacemaker, programmed as desired, dynamically interacts with a preselected intrinsic rhythm. Utilizing symbols prevalent in the pacing industry, this graphics-or...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:This study was designed to clarify the mechanism of reperfusion arrhythmia. In the mongrel dogs, the left anterior descending coronary artery was occluded for 15 min and then the ligation was released. The dogs were divided into two groups: one was the control group, and the other the indomethacin group in which indom...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(82)81012-1
更新日期：1982-10-01 00:00:00
abstract：BACKGROUND:Elevated levels of N-terminal pro brain natriuretic peptide (NT-proBNP) are associated with adverse cardiovascular outcome after ST elevation myocardial infarction (STEMI). We hypothesized that decreasing acuteness-score (based on the electrocardiographic score by Anderson-Wilkins acuteness score of myocardi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2016.11.002
更新日期：2017-01-01 00:00:00
abstract：:Voltage-sensitive dyes and high resolution optical mapping were used to analyze the characteristics of spiral waves of excitation in isolated ventricular myocardium. In addition, analytical techniques, which have been previously used in the study of the characteristics of spiral waves in chemical reactions, were appli...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(10)80029-9
更新日期：1992-01-01 00:00:00
abstract：:Pacemaker capture during the supernormal period was seen in a case of modulated parasystole where ectopic cycles occurred without any interposed nonparasystolic beat. This contrasts with previous clinical reports, since, in the latter, the parasystolic cycle length could not be measured directly. As in experimental st...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(89)90003-4
更新日期：1989-10-01 00:00:00
abstract：:Ventricular fibrillation (VF), uninterrupted, is fatal within minutes. Implantable cardioverter defibrillators (ICDs) sense ventricular electrograms (EGMs) during VF and detect the VF rhythm (a sequence of VF sensed events) to deliver a shock to terminate VF and save lives. VF sensing and detection in Medtronic ICDs h...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2018.08.034
更新日期：2018-01-01 00:00:00
abstract：:Implantable cardioverter defibrillators (ICDs) detect and defibrillate ventricular fibrillation (VF) and ventricular tachycardia (VT). Other therapies which use less energy are also available to terminate VT. Previous studies have shown that ICD rate schemes often misdiagnose VT as VF. In this study, an improved VF cl...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(98)80060-5
更新日期：1998-01-01 00:00:00
abstract：:Sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM) is caused by ventricular tachyarrhythmia that can be effectively treated by implantable cardioverter defibrillator (ICD) therapy. We report of a 28-year-old man with HCM and a dual chamber ICD, originally implanted for primary prevention of SCD, (programm...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.06.005
更新日期：2017-01-01 00:00:00
abstract：:The classic electrocardiographic (ECG) manifestation of stage I of acute pericarditis is diffuse ST elevation and PR depression with ST depression in lead aVR. One of the most common conditions, that is often confused with acute pericarditis, is the benign diffuse ST elevation, termed "early repolarization with ST ele...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.01.085
更新日期：2019-01-01 00:00:00
abstract：:His bundle electrograms of 40 patients developing Wenckebach block during atrial pacing and four with spontaneous Wenckebach block above the His were reviewed to determine the frequency of classical Wenckebach periodicity. Thirty patients had 143 Wenckebach cycles that were suitable for analysis. Cycles were evaluated...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(75)80003-3
更新日期：1975-01-01 00:00:00
abstract：:Recent studies have shown that ventricular myocardium is composed of at least 3 electrophysiologically distinct cell types: epicardial, endocardial, and M cells. Action potentials recorded from epicardial and M cells, unlike those recorded from endocardium, display a spike-and-dome morphology, the result of a prominen...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/s0022-0736(99)90074-2
更新日期：1999-01-01 00:00:00
abstract：:Five male patients with chronic stable ventricular arrhythmias underwent a placebo controlled ascending dose study with oral cibenzoline, a new type 1 antiarrhythmic drug. Ambulatory ECG (Holter) recordings and electrophysiologic studies were done while on placebo and on the maximum dose of cibenzoline. Drug toxicity,...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0022-0736(84)80020-5
更新日期：1984-01-01 00:00:00
abstract：:Successful curative treatment of right atrial tachycardia (AT) can be obtained provided detailed catheter activation mapping of the target site for radiofrequency energy application has been accomplished. However, right AT mapping may be difficult with a single roving catheter due to infrequent presence or noninducibi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(98)90298-9
更新日期：1998-01-01 00:00:00
abstract：:To assess the effect of pacing drive cycle length on induction of sustained monomorphic ventricular tachycardia, 40 patients were prospectively studied in the drug-free state. Ventricular extrastimuli were sequentially delivered at the same coupling interval at each of three drive cycle lengths (600, 500, and 400 ms) ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(92)90127-l
更新日期：1992-01-01 00:00:00
abstract：:QT and RR intervals' fluctuations are implicated in the development of malignant arrhythmias. Recent research has quantified repolarization lability using stochastic and linear methods. However, QT-RR intervals are nonlinearly coupled. To this end, QT and RR intervals were extracted from twenty four patients with acut...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2004.04.008
更新日期：2004-07-01 00:00:00
abstract：:Junctional ectopic tachycardia(JET) is a rare childhood arrhythmia originating from the area adjacent to the atrioventricular(AV) node. It often occurs after surgical procedures like repair of Tetralogy of Fallot, atrioventricular septal defect and ventricular septal defect, which are all performed in that area. While...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.01.015
更新日期：2017-01-01 00:00:00
abstract：:Direct Wenckebach periods in the left bundle branch with periods of 4:3 and 5:4 conduction alternating with 2:1 left bundle branch block (LBBB) were observed in a patient who was admitted because of congestive heart failure. There was no previous documented LBBB and serial electrocardiographic (ECG) mainfestations aft...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(80)80034-3
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND:Performance of ambulatory electrocardiography (AECG) may provide data useful for counseling patients regarding prognosis and for selecting potential patients for defibrillator implantation, but this practice remains controversial. METHODS:We reviewed clinical and AECG data on 355 patients diagnosed with dil...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2004.09.007
更新日期：2005-01-01 00:00:00
abstract：:A three-dimensional heart model was constructed to simulate late potentials and ventricular fibrillation (VF). The model consisted of 50,000 discrete elements having a 1.5-mm spatial resolution. Each element represented excitable ventricular tissue, including a conduction system, and was characterized with classical f...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Frank-lead electrocardiograms (ECGs) were recorded from 59 adult males with suspected coronary artery disease. Three records were recorded consecutively on frequency modulated tape for each patient in (1) supine position, (2) sitting position with arms relaxed, and (3) sitting position on bicycle with arms on bicycle ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(76)80021-0
更新日期：1976-01-01 00:00:00
abstract：:Magnesium ion infusion has been reported for treatment of hypomagnesemia often associated with myocardial infarction and with surgeries involving cardiopulmonary bypass (CPB). Magnesium infusion before CPB has been reported to adversely affect the ability to defibrillate after CPB. However, there are also reports of m...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(98)90045-0
更新日期：1998-04-01 00:00:00
abstract：:The American College of Cardiology recommends that patients with high risk acute myocardial infarction (AMI) be triaged to hospitals with percutaneous transluminal coronary angioplasty capability. However, there are no prehospital triage criteria to select candidates for bypassing community hospitals and being taken d...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.2000.20299
更新日期：2000-01-01 00:00:00
abstract：:In order to differentiate posterior (posterolateral) myocardial infarction (PMI) from the anterior shift of the QRS loop in "normal variant" cases using a vectorcardiogram, the T loop as well as the QRS loop in the transverse plane (TP) were analyzed in 34 elderly Japanese males with angiographically-proven PMI and in...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(86)80017-6
更新日期：1986-04-01 00:00:00
abstract：:A 21year old gentleman was admitted with shortness of breath and heart failure. He was noted to have incessant supraventricular tachycardia which was refractory to pharmacological and electrical cardioversion. Electrophysiology study revealed focal atrial tachycardia from an unusual location which was successfully abl...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.09.015
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Simulation of the electrical activation of the heart and its comparison with real in vivo activation is a promising method in testing potential determinants of excitation. Simulation of the electrical activity of the human heart is now emerging as a step forward for understanding and predicting electrophysio...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2008.12.008
更新日期：2009-03-01 00:00:00
abstract：:The peak-to-trough amplitude (sum of absolute values of maximum and minimum) of an isointegral QRST body surface map was shown, according to literary data, to be sensitive to changes in ventricular sympathetic tone. Statistics of this parameter were obtained, with an 80 electrodes array, in 135 healthy subjects of bot...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.2002.35844
更新日期：2002-10-01 00:00:00
abstract：:To show that cycle-length (CL) prolongation occurring at the onset of reentrant tachycardias may be associated with an increase in conduction time (CT), and to investigate the involvement of Na+ and Ca2+ channel activity, reentrant activity was induced by programmed stimulation in thin ventricular muscle slices with a...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1054/jelc.2000.18107
更新日期：2000-10-01 00:00:00
abstract：:Ventricular fibrillation (VF) had been traditionally considered as a highly disorganized process of random electrical activity emanating from multiple, short-lived, reentrant electrical waves. It is the incessant breakup of wave fronts and the creation of new daughter waves (wavebreaks) that perpetuate VF. Other studi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2007.06.021
更新日期：2007-11-01 00:00:00
