Research integrity and publication ethics.

abstract：OBJECTIVE:To analyze paraoxonase 1 (PON1) effect on monocyte-to-macrophage differentiation. METHODS AND RESULTS:THP-1 monocytic cell-line and mouse peritoneal macrophages (MPM) were studied. Markers for monocytes differentiation included: morphological changes, CD11b and CD36 expression, and cellular oxidative stress....

journal_title：Atherosclerosis

authors： Rosenblat M,Volkova N,Ward J,Aviram M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Atherosclerotic plaques are heterogeneous with respect to inflammation, calcification, vascularity, oxygen, and temperature. We hypothesized that they also vary in pH and measured pH in living human carotid endarterectomized atherosclerotic plaques (CEA), Watanabe heritable hyperlipidemic (WHHL) rabbit aorta...

journal_title：Atherosclerosis

authors： Naghavi M,John R,Naguib S,Siadaty MS,Grasu R,Kurian KC,van Winkle WB,Soller B,Litovsky S,Madjid M,Willerson JT,Casscells W

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Osteoporosis and coronary heart disease (CHD) are very common conditions among elderly people, and both represent a public health concern due to their prognostic consequences. Osteoporosis and CHD share many risk factors and pathophysiological mechanisms, such as calcification pathways. Clinical evi...

journal_title：Atherosclerosis

authors： Campos-Staffico AM,Freitas WM,Carvalho LSF,Coelho-Filho OR,Nadruz W Jr,Oliveira RB,Sposito AC,Brasilia Study on Healthy Aging and Brasilia Heart Study.

更新日期：2020-01-01 00:00:00

abstract：:The St. Thomas mixed hyperlipidaemic (SMHL) rabbit exhibits an inherited hyperlipidaemia similar to that seen in familial combined hyperlipidaemia (FCHL). In this study, we investigated whether the SMHL rabbit is insulin resistant, a condition often associated with FCHL. Six young and six mature combined hyperlipidaem...

journal_title：Atherosclerosis

authors： de Roos B,Caslake MJ,Ardern HA,Martin Benson G,Suckling KE,Packard CJ

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Atherosclerosis starts early in life. We aimed to assess the dimension and progression of the intima-media thickness, a surrogate marker for early vascular aging, and its association with a broad palette of cardiovascular risk and lifestyle factors in a large cohort of healthy adolescents. METHODS:...

journal_title：Atherosclerosis

authors： Staudt A,Stock K,Gande N,Bernar B,Hochmayr C,Pechlaner R,Kiechl SJ,Geiger R,Griesmacher A,Anliker M,Kiechl S,Kiechl-Kohlendorfer U,Knoflach M,Early Vascular Ageing (EVA) Study Group.

更新日期：2020-07-01 00:00:00

abstract：:A major gene hypothesis for heparin releasable plasma lipoprotein lipase (PH-LPL) activity was assessed using segregation analyses of data on 495 members in 98 normolipidemic sedentary families of Caucasian descent who participated in the HERITAGE Family Study. Segregation analyses were performed on PH-LPL adjusted fo...

journal_title：Atherosclerosis

authors： Hong Y,Rice T,Després JP,Gagnon J,Nadeau A,Bergeron J,Pérusse L,Bouchard C,Leon AS,Skinner JS,Wilmore JH,Rao DC

更新日期：1999-06-01 00:00:00

abstract：:The effect of triiodothyronine (T3) on prostacyclin production in rat aortic smooth muscle cells was investigated by using an intact cell assay system. T3 at its physiological concentrations has no significant effect on smooth muscle cell proliferation, but it does significantly stimulate prostacyclin production by th...

journal_title：Atherosclerosis

authors： Nakao J,Chang WC,Murota S,Orimo H

更新日期：1981-07-01 00:00:00

abstract：:The aims of this study were to determine whether non-invasive measurement of endothelial function in conduit arteries reflects that of subcutaneous resistance arteries measured in vitro and to examine whether there is an endothelial dysfunction also in resistance arteries in patients with a previous myocardial infarct...

journal_title：Atherosclerosis

authors： Agewall S,Henareh L,Kublickiene K

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to determine the extent and sources of oxidative stress within skeletal muscle following an acute bout of contractile claudication. Twenty-four hours after unilateral ligation of the femoral artery, rat hind limbs were stimulated in vivo for 30 min, and force production measured. One-hour...

journal_title：Atherosclerosis

authors： Judge AR,Dodd SL

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:The apolipoprotein E mimetic peptide Ac-hE18A-NH(2), capable of reducing plasma cholesterol and possessing anti-inflammatory properties, was compared with the well-studied anti-atherogenic apoA-I mimetic peptide 4F for reducing lesion formation in female apoE null mice with already existing lesions. METHODS ...

journal_title：Atherosclerosis

authors： Nayyar G,Garber DW,Palgunachari MN,Monroe CE,Keenum TD,Handattu SP,Mishra VK,Anantharamaiah GM

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Lipoprotein(a) [Lp(a)] consists of apolipoprotein B-100 (apoB-100) as part of an LDL-like particle and the covalently linked glycoprotein apolipoprotein(a) [apo(a)]. Detailed mechanisms of its biosynthesis, assembly, secretion and catabolism are still poorly understood. To address the Lp(a) assembly mechanism...

journal_title：Atherosclerosis

authors： Frischmann ME,Ikewaki K,Trenkwalder E,Lamina C,Dieplinger B,Soufi M,Schweer H,Schaefer JR,König P,Kronenberg F,Dieplinger H

更新日期：2012-12-01 00:00:00

abstract：AIMS:This cross-sectional study tested the hypothesis that treatment with the combination of Ezetimibe/Simvastatin (Vytorin) leads to broader changes in the expression levels of immunomodulatory genes as compared to Simvastatin monotherapy. METHODS:Illumina's GenomeStudio gene expression module was used to compare gen...

journal_title：Atherosclerosis

authors： Sternberg Z,Chichelli T,Sternberg D,Hojnacki D,Drake A,Liu S,Hu Q,Munschauer F

更新日期：2013-12-01 00:00:00

abstract：:The aim of this study was to determine whether an abnormality in low density lipoprotein (LDL) metabolism could be demonstrated in fibroblasts cultured from normolipidaemic subjects with atherosclerosis. Seventeen male subjects aged 30-55 years with normal plasma lipid concentrations were divided into 2 groups on the ...

journal_title：Atherosclerosis

authors： Behrman RG,Wynn V

更新日期：1982-04-01 00:00:00

abstract：:The aim of this study was to examine whether the well-established effect of the common TaqIB polymorphism in intron 1 of the gene for cholesterol ester transfer protein (CETP) on high density lipoprotein cholesterol (HDL-C) concentration and increased risk of myocardial infarction (MI), could be explained by the recen...

journal_title：Atherosclerosis

authors： Eiriksdottir G,Bolla MK,Thorsson B,Sigurdsson G,Humphries SE,Gudnason V

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Toll like receptors (TLR) have been recognized for their role in atherosclerotic lesion development and progression. Endogenous TLR ligands that are also expressed in atherosclerotic tissues have been shown to promote atherosclerosis in mice. Since repetitive stimulation of TLR induces an attenuated inflamma...

journal_title：Atherosclerosis

authors： Schoneveld AH,Hoefer I,Sluijter JP,Laman JD,de Kleijn DP,Pasterkamp G

更新日期：2008-03-01 00:00:00

abstract：:The detailed distribution of atherosclerotic lesions in the branching region of the left main coronary artery in man was studied. Tissue cubes of the hearts, containing the left coronary arteries, were removed, and 1.5-mm-thick parallel and consecutive slices were cut perpendicular to the main coronary artery. Histolo...

journal_title：Atherosclerosis

authors： Grøttum P,Svindland A,Walløe L

更新日期：1983-04-01 00:00:00

abstract：:Rabbit apolipoprotein A-I (apo A-I) of molecular weight 27,612 contained 241 amino acids. In contrast to its human counterpart which has 3 methionine residues, the rabbit protein possesses only one and therefore produces 2 fragments after CNBr cleavage (CNBr I and II, NH2- and COOH-terminal, respectively). From a seri...

journal_title：Atherosclerosis

authors： Leroy A,Vu-Dac N,Theret N,Pio F,Fruchart JC

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The exact mechanism of premature atherosclerosis in diabetes is still unclear. Inappropriate activation of the renin-aldosterone-angiotensin system may be an important risk factor for cardiovascular disease. We investigated whether renin and aldosterone are associated with vasoactive peptides midreg...

journal_title：Atherosclerosis

authors： Then C,Rottenkolber M,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Rathmann W,Bidlingmaier M,Reincke M,Seissler J

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Infusion of high-density lipoprotein (HDL) mimetics failed to induce regression of atherosclerosis in recent randomized clinical trials. However, patients in these previous trials had normal levels of HDL-cholesterol, which potentially limited efficacy. Patients with very low levels of HDL-cholester...

journal_title：Atherosclerosis

authors： Zheng KH,Kaiser Y,van Olden CC,Santos RD,Dasseux JL,Genest J,Gaudet D,Westerink J,Keyserling C,Verberne HJ,Leitersdorf E,Hegele RA,Descamps OS,Hopkins P,Nederveen AJ,Stroes ESG

更新日期：2020-10-01 00:00:00

abstract：:This prospective randomized trial was designed to elucidate clinically the effect of fluvastatin on inhibiting oxidation of the low density lipoprotein (LDL) and improving the vascular endothelial function as well as its lipid-lowering effects, in comparison with pravastatin. Of 64 consecutive dyslipidemic patients, 4...

journal_title：Atherosclerosis

authors： Inoue T,Hayashi M,Takayanagi K,Morooka S

更新日期：2002-02-01 00:00:00

abstract：:The effect of different fat loads on postprandial lipemia and hemostatic activity was examined in 10 middle-aged men using 3 different meals. One meal was rich in saturated fatty acids (cream), the other rich in n-6 polyunsaturated fatty acids (sunflower oil) and the third was fat-free containing only carbohydrates. L...

journal_title：Atherosclerosis

authors： Salomaa V,Rasi V,Pekkanen J,Jauhiainen M,Vahtera E,Pietinen P,Korhonen H,Kuulasmaa K,Ehnholm C

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:Postprandial hyperlipemia has been shown to impair endothelial function and contribute to the development of atherosclerosis. We investigated the association between postprandial lipid profiles and endothelial function, and we examined the effects of ezetimibe on postprandial hyperlipemia and lipemia-induced ...

journal_title：Atherosclerosis

authors： Yunoki K,Nakamura K,Miyoshi T,Enko K,Kohno K,Morita H,Kusano KF,Ito H

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Lipid rafts are cholesterol-enriched microdomains on cell membranes. We hypothesized that these microdomains could involve modified low-density lipoprotein (LDL) uptake. METHODS AND RESULTS:Co-localizations of cholesterol-enriched microdomains and CD204 during the uptake of acetyl LDL (AcLDL) and oxidized LD...

journal_title：Atherosclerosis

authors： Kiyanagi T,Iwabuchi K,Shimada K,Hirose K,Miyazaki T,Sumiyoshi K,Iwahara C,Nakayama H,Masuda H,Mokuno H,Sato S,Daida H

更新日期：2011-03-01 00:00:00

abstract：AIMS:Besides carotid or cardiac embolism, stroke can occur via microangiopathy (small arterial disease [SAD]) and macroangiopathy (intracranial atherosclerotic stroke [ICAS]) of the intracranial vasculature. There have been efforts to identify risk factors specific to microangiopathy and macroangiopathy, including vasc...

journal_title：Atherosclerosis

authors： Bang OY,Chung JW,Ryoo S,Moon GJ,Kim GM,Chung CS,Lee KH

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Elevated homocysteine is associated with ischaemic heart disease (IHD). The C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene results in reduced MTHFR enzyme activity and reduced methylation of homocysteine to methionine resulting in mild hyperhomocysteinaemia. Case-control associati...

journal_title：Atherosclerosis

authors： Spence MS,McGlinchey PG,Patterson CC,Belton C,Murphy G,McMaster D,Fogarty DG,Evans AE,McKeown PP

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Given the high risk of cardiovascular disease in South Asians and the importance of inflammation in coronary heart disease we tested the hypothesis that circulating C-reactive protein (CRP) and interleukin 6 (IL-6) would be higher in healthy British born infants of South Asian origin than in infants of Europe...

journal_title：Atherosclerosis

authors： Oldroyd JC,Heald A,Bansal N,Vyas A,Siddals K,Gibson M,Clayton P,Cruickshank JK

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:We sought to determine whether mitral annular calcification (MAC) predicts mortality and cardiac disease in a group of renal transplant candidates. METHODS:Hundred and forty patients were prospectively studied. All had echocardiography and coronary angiography. Significant coronary artery disease (CAD) was ...

journal_title：Atherosclerosis

authors： Sharma R,Pellerin D,Gaze DC,Mehta RL,Gregson H,Streather CP,Collinson PO,Brecker SJ

更新日期：2007-04-01 00:00:00

abstract：:Large (Sf greater than 100) and small (Sf 100-20) very low density lipoprotein (VLDL) particles were isolated by density gradient ultracentrifugation and characterized chemically in 8 patients with primary hypertriglyceridemia before and after 6 weeks treatment with 4 grammes daily of nicotinic acid (NA). Concomitant ...

journal_title：Atherosclerosis

authors： Tornvall P,Hamsten A,Johansson J,Carlson LA

更新日期：1990-10-01 00:00:00

abstract：:The evaluation of the health effects of low-dose ionizing radiation has always been a focus of debate and investigation within the scientific community. During the last decade, epidemiological studies provided evidence that an excess risk of cardiovascular diseases (CVDs) can be associated with moderate and low dose r...

journal_title：Atherosclerosis

authors： Borghini A,Gianicolo EA,Picano E,Andreassi MG

更新日期：2013-09-01 00:00:00

abstract：:Variation in the APOA5 gene has been shown to be associated with triglyceride levels in several independent population studies. It was our objective to determine if a relationship existed between selected genotypes or haplotypes of the APOA5 gene and findings on selective coronary angiography (SCA) in an independent c...

journal_title：Atherosclerosis

authors： Lee KW,Ayyobi AF,Frohlich JJ,Hill JS

更新日期：2004-09-01 00:00:00