An approach to noninvasive delivery, biodistribution, and fertility control potential evaluation of the Cuproferrogel iron oxide-copper-styrene maleic anhydride-dimethyl sulphoxide in the female.

Abstract:

:Under guidance of an external pulsed magnetic field the Cuproferrogel iron oxide-copper-styrene maleic anhydride-dimethyl sulphoxide delivered into the rat/rabbit oviduct resulted in oocytes with granulated cytoplasm, zona enlargement, membrane disintegration, and finally loss of viability in 72 hours. Also, the percentage biodistribution of magnetic and electrically conductive particles observed under safe level advocates the use of Cuproferrogel as a potential female fertility control molecule.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Jha R,Jha PK,Rana SV,Guha SK

doi

10.1016/j.fertnstert.2010.06.032

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

2850-3

issue

7

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)00985-4

journal_volume

94

pub_type

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