Early and long term outcome in children with esophageal atresia treated over the last 22 years.

Abstract:

BACKGROUND:The survival of infants born with esophageal atresia (EA) is > 90% at present. The purpose of this study was to evaluate early complications and long term outcome in children with EA treated at our institution. METHODS AND PATIENTS:Retrospective analysis of 111 children with EA undergoing repair of EA or tracheoesophageal fistula (TEF). Assessment of early and intermediate complications as well as long term morbidity and mortality. RESULTS:Primary anastomosis was performed in 90 (81%) and secondary anastomosis in 7 patients (6%). Gastric transposition was carried out in 14 children (13%). The postoperative mortality was 14/111 (12.6%) and could be estimated by the Spitz classification. At the age of 10 years, 33 patients (72%) were swallowing without problems, 39 children (85%) were eating at least most of the time with pleasure but 19 children (41%) had a body weight less than the 25 (th) percentile. Staged repair by gastric transposition resulted in the least amount of motility dysfunction. Long-term respiratory morbidity was high. CONCLUSION:The survival of children with EA has improved in the last two decades. For risk assessment the Spitz' classification is valid. Long term gastrointestinal and respiratory morbidity remains high. In children with long-gap EA gastric transposition performed as a staged procedure has satisfactory results and seems superior to techniques preserving the native esophagus.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Lacher M,Froehlich S,von Schweinitz D,Dietz HG

doi

10.1055/s-0030-1249610

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

296-301

issue

5

eissn

0300-8630

issn

1439-3824

journal_volume

222

pub_type

杂志文章
  • Differences of Medical Care for Acute Severe Viral Bronchiolitis in Two Urban Areas in Europe.

    abstract:BACKGROUND:Acute viral bronchiolitis is a frequent disease in infancy. There is little knowledge on medical care of severely affected infants in different European countries. PATIENTS:Infants (n=146) with bronchiolitis requiring respiratory support in winter season 2015/2016 treated in either one of two regions in Cen...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-0611-6109

    authors: Dohna-Schwake C,Mücher K,Stehling F,Rothoeft T,Roll C,Brevis Nuńez F,Seiffert P,Heister P,Hofmann M,Stein A,Jacobs A,Zuzak T,Durand P,Felderhoff-Müser U,Tissières P

    更新日期:2018-09-01 00:00:00

  • [Plasma separation as an effective treatment of glomerulonephritis in lupus erythematosus].

    abstract::Positive anti-DNA-antibodies and lowered C3 and C4 levels were found in serum of a 13 year old girl presenting with edema, microscopic hematuria and proteinuria. Renal biopsy revealed diffuse endo- and extracapillary glomerulonephritis with mesangial deposits of IgA, IgG, IgM, C1q, C3 and fibrinogen. In spite of treat...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034411

    authors: Michalk D,Scharf J,Waldherr R

    更新日期:1983-11-01 00:00:00

  • [Anaerobic microflora of praepubertal children (author's transl)].

    abstract::Bacteriologic cultures of the vagina and the cervix of 38 praepubertal children, aged 3 months to 16 years (average age 9 years) from the outpatient department for infants and juveniles of the 1st Department of Obstetrics and Gynecology of the University of Vienna were obtained vaginascopically using anaerobic transpo...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033769

    authors: Gerstner G,Boschitsch E,Grünberger W,Rotter M

    更新日期:1982-01-01 00:00:00

  • [A study group on brain tumors in childhood. Introduction, establishment and aims].

    abstract::Tumors of the central nervous system account for 15.7% of all malignancies registered at the documentation center for childhood malignancies in Western Germany. This group constitutes the largest entity of solid tumors. With the exception of medulloblastoma the five-year survival probability of children with cns tumor...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026789

    authors: Kühl J

    更新日期:1987-05-01 00:00:00

  • [Click-evoked otoacoustic emissions and acoustic brain stem potentials in early detection of hearing disorders in premature and newborn infants after neonatal critical care].

    abstract::Evoked otoacoustic emissions (EOAE) and brainstem acoustic evoked potentials (BAEP) were recorded from 78 children following neonatal intensive care. In 23% no EOAE could be obtained. Hearing impairment in the BAEP was found in 9%. In 22% negative EOAE were found in spite of normal BAEP. According to the latency-inten...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046586

    authors: Lauffer H,Pröschel U,Gerling S,Wenzel D

    更新日期:1994-03-01 00:00:00

  • Laryngomalacia and complicated, life-threatening mTOR-positive Kaposiform hemangioendothelioma cured by Supraglottoplasty and sirolimus.

    abstract::The therapy of complicated Kaposiform hemangioendothelioma (KHE) is still difficult. We present the first case of laryngomalacia with simultaneous mammalian target of Rapamycin (mTOR)-positive KHE of the neck and thoracic inlet and concurrent Kasabach-Meritt Phenomenon (KMP) in an 11-month-old boy suffering life-threa...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1372587

    authors: Schroeder U,Lauten M,Stichtenoth G,Gebhard MP,Buchholz M,Kaiser MM

    更新日期:2014-11-01 00:00:00

  • [DNA aneuploidy in children with acute leukemia: II. Correlation with the phenotype of blasts, clinical picture and course of disease].

    abstract::Analysis of the cellular DNA content was carried out in 162 children with ALL and 34 children with AML admitted to the university children's hospital Münster between 1979 and 1984. DNA aneuploidies were identified at a similar frequency in ALL (40%) and AML (44%). However, the degree of DNA aneuploidies (DNA-index) wa...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1033972

    authors: Ritter J,Hiddemann W,Wörmann B,Büchner T,Schellong G

    更新日期:1985-05-01 00:00:00

  • [Therapy-related pamphlet for patients in pediatric oncology].

    abstract::This notebook which is of postcard size contains important information in case of emergency and details about the current illness and treatment. It contains follow-up information about the pattern of growth, endocrinological development and assessment of renal tubular function. The necessary follow-up investigations a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046621

    authors: Maass E

    更新日期:1994-07-01 00:00:00

  • [What is a Sufficient Blood Pressure in the Preterm Newborn?].

    abstract::Hypotension is diagnosed in a high percentage of very low birth weight infants, particularly in the first 24 hours after birth and the resultant clinical approach is to support the blood pressure vigorously. However, the research base is not yet available to give a definite answer to the question, which blood pressure...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2003-36890

    authors: Stopfkuchen H

    更新日期:2003-01-01 00:00:00

  • [Undetected Cases of Non-Accidental Burns in Children - Preventive Strategies].

    abstract:BACKGROUND:Thermal injuries are a frequent cause of accidents within the pediatric population that may result in long periods of hospitalization as well as severe physical and mental impairment and lifelong consequences. Especially in infants, burns caused by scalding are the most common cause of injury. Beside acciden...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0043-119416

    authors: Klinke M,Schmidt CM,Tegtmeyer L,Reinshagen K,Boettcher M,Koenigs I

    更新日期:2018-03-01 00:00:00

  • Newly diagnosed immune thrombozytopenia--German guideline concerning initial diagnosis and therapy.

    abstract::Newly diagnosed immune thrombocytopenia occurs in 3-5/100 000 children < 14 y per year. Bleeding symptoms do not correlate with platelet count. Diagnostic approach includes history, clinical examination and analysis of blood count with blood smear by experienced hematologist. Additional investigations are only necessa...

    journal_title:Klinische Padiatrie

    pub_type: 共识发展会议,杂志文章

    doi:10.1055/s-0032-1306277

    authors: Eberl W,Dickerhoff R,Pediatric Committee of Society of Thrombosis and Hemostasis Research.

    更新日期:2012-04-01 00:00:00

  • [Therapy of testicular germ cell tumors. Current status of the MAHO studies].

    abstract::The GPOH-MAHO trials designed in 3/82 and 7/88 for treatment of childhood testicular germ cell tumors registered 3/92 105 pts. In MAHO 82 study 57 pts. and in MAHO 88 study 48 pts. were treated. Histologically 60% of the tumors revealed yolk sac tumors (YST), 22% teratomas (TD) and 18% malignant teratomas (MTI, MTU, M...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025231

    authors: Haas RJ,Schmidt P,Göbel U,Harms D

    更新日期:1993-07-01 00:00:00

  • [Familial chromosome translocation (1;5;15) as a cause of partial trisomy 1p].

    abstract::An unbalanced structural chromosome aberration was found in a 6-year-old girl. Mother and maternal grandmother were shown to be carriers of a complex balanced translocation involving chromosomes 1, 5 and 15 and are of normal phenotype. The unbalanced status in the proband was defined as a partial trisomy 1p21-1p31. Pa...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026754

    authors: Schürmann M,Wethling H,Niemeyer ML,Schwinger E

    更新日期:1987-01-01 00:00:00

  • [Glutaric acidemia/glutaric aciduria I as differential chorea minor diagnosis].

    abstract::Glutaracidemia/glutaraciduria type I is an acute or subacute neuropathic disorder of infancy or early childhood. The following symptoms characterize the clinical course: macrocephalus present at birth, cerebral atrophy revealed by CT or MRI scans, most striking in the frontal and temporal lobes, choreoathetosis and dy...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025211

    authors: Voll R,Hoffmann GF,Lipinski CG,Trefz FK,Weisser J

    更新日期:1993-03-01 00:00:00

  • [Robin-Silverman-Smith (fetal face) syndrome].

    abstract::Report of a case of the fetal face syndrome associated with severe oligophrenia and septum pellucidum cyste in a male patient aged 30 years. The case demonstrates the good prognosis of the hypogenitalism resp. small genitalia; the correct diagnosis in this syndrome can the patients save a plastic of the penis. ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046568

    authors: Fehlow P,Walther F,Pfeifer T,Schuchard UM

    更新日期:1995-11-01 00:00:00

  • [Fertility Preservation in Prepubertal und Pubertal Children and Adolescents].

    abstract:BACKGROUND:Due to rising survival rates in cancer and autoimmune diseases fertility preservation before gonadotoxic therapies has become increasingly important. Although fertility can be significantly affected by gonadotoxic therapies, the possibility of fertility preservation during childhood has not been sufficiently...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0044-100396

    authors: Sänger N,Jarisch A,Ochsendorf F,Klingebiel T,Liebenthron J,Kliesch S,von Wolff M

    更新日期:2018-02-08 00:00:00

  • Cerebellar mutism syndrome.

    abstract::Since 1980, a growing number of pediatric patients with mutism following posterior fossa surgery have been recognized. This syndrome typically affects children and in rare cases young adults who become mute one or two days after tumor operation but do not show disturbances of consciousness or language comprehension. T...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043886

    authors: Janssen G,Messing-Jünger AM,Engelbrecht V,Göbel U,Bock WJ,Lenard HG

    更新日期:1998-07-01 00:00:00

  • [Waardenburg syndrome type I--autosomal dominant hereditary combination of multiple facial anomalies with cochlear deafness (author's transl)].

    abstract::Waardenburg syndrome Type I is described on the basis of an observation of a family. The characteristic signs including lateral displacement of medial canthi ("telecanthus"), wide bridge of the nose, white forelock and severe cochlear deafness are found in one female patient only; however, her eyes are not of differen...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033785

    authors: Meinecke P

    更新日期:1982-03-01 00:00:00

  • [Pneumatocele after hydrocarbon aspiration].

    abstract::Report of accidental ingestion and aspiration of lamp oil of a boy aged 16 months. He develops in a few hours a severe pneumonitis with tachycardia. Echocardiography shows diminished contractability. After losing his symptoms, the chest x-rays on the 13th day show bilateral pneumatoceles. The course remains asymptomat...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043916

    authors: Leuchter D,Stübecke W,Oberschulte-Beckmann D

    更新日期:1998-11-01 00:00:00

  • [Treatment of hemophagocytic lymphohistiocytosis, HLH, with bone marrow transplantation].

    abstract::Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of infancy and young childhood. The clinical presentation includes recurrent unexplained fever with hepatosplenomegaly. Cytopenia, hypofibrinogenemia and/or hypertriglyceridemia and hemophagocytosis in bone marrow, spleen and lymphnode confirm the diagnosis. H...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043876

    authors: Dürken M,Schneider EM,Blütters-Sawatzki R,Stollmann-Gibbels B,Nessler G,Bretz R,Körholz D,Probst EN,Holsten-Griffin H,Harps E,Zander AR,Janka GE

    更新日期:1998-07-01 00:00:00

  • [Quality standards and their assurance for study centers in the competence network malignant lymphoma].

    abstract:BACKGROUND:The aim of most of the trials of the Competence Network Malignant Lymphoma is to optimize the standard treatment of lymphoma using only registered drugs in the case of medicinal therapies (quality assurance protocols). In contrast to regulatory trials, special regulations for quality assurance protocols are ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2003-45493

    authors: Pfistner B,Mehl C,Klöss M,Löffler M,Herrmann-Frank A,Diehl V

    更新日期:2003-11-01 00:00:00

  • Symptom patterns in childhood arterial ischemic stroke: Analysis of a population-based study in Germany.

    abstract:HINTERGRUND: Die zeitliche Verzögerung zwischen Symptombeginn und Diagnose ist eine Herausforderung in der Behandlung von Kindern mit arteriell ischämischem Schlaganfall. Frühere Studien zur klinischen Präsentation beschäftigten sich v. a. mit kumulativen Symptomen. ZIELSETZUNG: Ziel dieser Studie ist es, mögliche Sym...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-0684-9794

    authors: Gerstl L,Weinberger R,von Kries R,Heinen F,Sebastian Schroeder A,Veronika Bonfert M,Borggräfe I,Tacke M,Vill K,N Landgraf M,Kurnik K,Olivieri M

    更新日期:2018-10-01 00:00:00

  • [Combined treatment strategy in over 200 children with Hodgkin's disease: graduated chemotherapy, involved field irradiation with low dosage and selective splenectomy. A report of the cooperative therapy study DAL-HD-82].

    abstract:UNLABELLED:It was the aim of the cooperative therapy study HD-82 for children with Hodgkin's disease to reduce chemo- and radiotherapy and to investigate of a strategy for selective splenectomy previously developed in the Hodgkin study HD-78. Between December 1981 and December 1984 207 patients (131 boys and 76 girls) ...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1026870

    authors: Schellong G,Brämswig J,Ludwig R,Gerein V,Jobke A,Jürgens H,Kabisch H,Stollmann B,Weinel P,Gadner H

    更新日期:1986-05-01 00:00:00

  • [Neuropsychological sequelae in children with AML treated with or without prophylactic CNS-irradiation].

    abstract:BACKGROUND:In study AML-BFM 87 the relapse rate was lower in patients receiving cranial irradiation (CRT). However, CRT has always been associated with adverse cognitive side effects. Therefore, the impact of CRT on neuropsychological function in children with AML was retrospectively evaluated. PATIENTS:We tested 53 c...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2002-19861

    authors: Reinhardt D,Thiele C,Creutzig U,AML-BFM-Studiengruppe.

    更新日期:2002-01-01 00:00:00

  • [Cow milk-specific humoral and cellular immune response in infants with high risk of atopy under feeding a whey hydrolysate infant formula].

    abstract:BACKGROUND:Hypoallergenic infant formulas (HAF) were developed for atopy prevention in infants with high risk of atopy if these cannot be breastfed. HAF mount an antigen-specific immune response in infants. The aim of the study was to analyse the immune response in infants fed with a new infant formula based on a whey ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2003-42664

    authors: Nentwich I,Pazdírková A,Koberská I,Pokojská E,Szépfalusi Z,Lokaj J

    更新日期:2003-09-01 00:00:00

  • [Comparison of the acetylcholine receptor antibody titer and clinical course in neonatal myasthenia].

    abstract::Ten to fifteen percent of infants of myasthenic mothers develop neonatal myasthenia independent of the severity of the maternal disease. The antiacetylcholin receptor-protein antibodytiter (AChR-AK) was followed through the first twelve months in a boy who's mother suffered from myasthenia gravis (M.G.) since twelve y...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034089

    authors: Lischka A,Grisold W,Pollak A,Zeitelhofer J,Riegler R,Weninger M

    更新日期:1984-09-01 00:00:00

  • [No motivation, no time, no money--does oncologic graduate and continuing education still have a future? Presentation at the 50th Scientific Session of the Society of Pediatric Oncology and Hematology within the scope of the KOK and PSAPOH general session

    abstract::For many years the nursing profession has been considered a dead-end street without any prospects of career advancement or continued qualification. This situation has thoroughly changed. Nursing as an academic specialty has been established in 24 colleges. Furthermore, on-the-job specialty training has become availabl...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043896

    authors: Voss H

    更新日期:1998-07-01 00:00:00

  • [Heroin withdrawal syndrome in newborns (author's transl].

    abstract::A case of a severe heroin withdrawal syndrom in a newborn infant is reported. Diagnostic and therapeutic aspects of the disease are reviewed. ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Petrich C,Voss HV,Bretschneider A,Göbel U

    更新日期:1976-11-01 00:00:00

  • [Doppler echocardiographic investigation of left ventricular diastolic function in preterm infants with and without a patent ductus arteriosus].

    abstract::We studied the influence of preload augmentation on Doppler-derived left ventricular diastolic function parameters in infants with a birth weight <1500 g. In 44 neonates with a closed duct and 29 neonates with an open ductus arteriosus a complete echocardiographic study including Doppler investigations of the mitral i...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2004-817684

    authors: Schmitz L,Stiller B,Koehne P,Koch H,Lange PE

    更新日期:2004-01-01 00:00:00

  • [Intracranial pressure increase following treatment nalidixic acid in a child aged 3 1/2 years (author's transl)].

    abstract::Neurological symptoms developed in a girl aged three-and-a-half years during treatment with nalidixic acid. The symptoms progressed even after the preparation had been discontinued, and culminated in the development of a transient intracranial pressure increase. ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Lorenz R

    更新日期:1979-07-01 00:00:00