Attention-deficit/hyperactivity disorder and the dopaminergic hypotheses.

abstract：:Schizophrenia is a devastating psychiatric disorder; the diagnosis probably encompasses a number of illnesses with similar clinical presentations, complicating both treatment and studies into the pathology of the disorder. The development of antipsychotic medications revolutionized treatment for the disorder. However,...

journal_title：Expert review of neurotherapeutics

authors： Scarr E,Dean B

更新日期：2009-01-01 00:00:00

abstract：:Post-traumatic headache (PTH) is a very controversial disorder, particularly when it comes to chronic PTH following mild closed head injury and headache attributed to whiplash injury. Nevertheless, mild traumatic brain injury is very common in Western societies, affecting approximately 1.8 million individuals in the U...

journal_title：Expert review of neurotherapeutics

authors： Obermann M,Holle D,Katsarava Z

更新日期：2009-09-01 00:00:00

abstract：:Advances in molecular biology and virology in recent years have enabled the technology of gene transfer to proceed forward. Parkinson's disease (PD) is a particularly appropriate target for gene therapy since the brain pathology is fully characterized and relatively well circumscribed largely within the nigrostriatal ...

journal_title：Expert review of neurotherapeutics

authors： Mochizuki H

更新日期：2007-08-01 00:00:00

abstract：INTRODUCTION:Patients with multiple sclerosis (MS) may suffer from spasticity and pain during their disease course. Baclofen, dantrolene, diazepam and gabapentin have been used as first-line options to treat these conditions, with modest results. Medical use of marijuana smoking has bypassed traditional clinical trials...

journal_title：Expert review of neurotherapeutics

authors： Fragoso YD,Carra A,Macias MA

更新日期：2020-08-01 00:00:00

abstract：:The saga of harmful administration of levodopa (LD) in the treatment of Parkinson's disease (PD) resulted from outcomes of animal trials and cell culture studies. They were initiated after the clinical observation of onset of motor complications related to the short plasma half-life of the drug in PD patients. This di...

journal_title：Expert review of neurotherapeutics

authors： Müller T

更新日期：2008-06-01 00:00:00

abstract：:The spectrum of idiopathic inflammatory-demyelinating disorders of the CNS is classified based on clinical symptoms and signs, clinical severity, lesion distribution, neuroimaging features and cerebrospinal fluid characteristics. There is a wide variety of conditions in this broad spectrum. In some cases, the dissemin...

journal_title：Expert review of neurotherapeutics

authors： Idiman E,Ozakbaş S

更新日期：2011-03-01 00:00:00

abstract：:Central pain, which follows brain and spinal cord injury remains an ill-treated entity affecting approximately 1-2 million people worldwide. When oral drugs fail, either immediately or in the long run, the only therapeutic option is neuromodulation, via either electrical or chemical means. The whole spectrum of neurom...

journal_title：Expert review of neurotherapeutics

authors： Canavero S,Bonicalzi V

更新日期：2003-09-01 00:00:00

abstract：:Genetic imaging has become an increasingly popular tool that utilizes neuroimaging techniques to investigate the impact of genetic variation on the structure, function and connectivity of the brain. Combining genetic and neuroimaging domains is a promising approach to further the understanding of the neural mechanisms...

journal_title：Expert review of neurotherapeutics

authors： Redpath HL,Lawrie SM,Sprooten E,Whalley HC,McIntosh AM,Hall J

更新日期：2013-01-01 00:00:00

abstract：:Epilepsy is the most common serious neurological disorder in the elderly after stroke and dementia. It may be more important for elderly people because it is intermittent and unpredictable. There is no reliable diagnostic test and so its diagnosis and management requires clinical acumen and experience. The situation i...

journal_title：Expert review of neurotherapeutics

authors： Johnston A,Smith PE

更新日期：2010-12-01 00:00:00

abstract：:Fingolimod is the first oral agent approved in the USA for the treatment of relapsing forms of multiple sclerosis. Fingolimod is a sphingosine 1-phosphate receptor modulator that binds to sphingosine 1-phosphate receptors on lymphocytes, resulting in a downregulation of the receptor and a reversible sequestration of l...

journal_title：Expert review of neurotherapeutics

authors： Jeffery DR,Markowitz CE,Reder AT,Weinstock-Guttman B,Tobias K

更新日期：2011-02-01 00:00:00

abstract：INTRODUCTION:Non-convulsive status epilepticus (NCSE) is a complex and diverse condition which is often an under-recognised entity in the intensive care unit. When NCSE is identified the optimal treatment strategy is not always clear. Areas covered: This review is based on a literature review of the key literature in t...

journal_title：Expert review of neurotherapeutics

authors： Kinney MO,Kaplan PW

更新日期：2017-10-01 00:00:00

abstract：:The American Academy of Neurology is an international professional organization of more than 22,000 neurologists and neuroscience professionals. This year the annual meeting was held in Toronto, ON, Canada. A large number of scientific sessions presented numerous advances in the diagnosis, molecular pathogenesis and t...

journal_title：Expert review of neurotherapeutics

authors： Yiu EM,Banwell B

更新日期：2010-08-01 00:00:00

abstract：:Introduction: Chronic Tic Disorders and Tourette's Disorder (collectively referred to as TD) are characterized by sudden, rapid, and repetitive motor movements or vocalizations called tics. Children, adolescents, and adults with TD often experience co-occurring psychiatric symptoms and impairments in multiple domains....

journal_title：Expert review of neurotherapeutics

authors： Essoe JK,Grados MA,Singer HS,Myers NS,McGuire JF

更新日期：2019-11-01 00:00:00

abstract：:Central nervous system idiopathic inflammatory demyelinating disorders are a heterogenous group of diseases that share inflammation and demyelination as key features. Although the exact pathophysiology remains to be fully unveiled, these conditions are challenging to clinicians who seek specific therapeutic options fo...

journal_title：Expert review of neurotherapeutics

authors： Khoshnam M,Freedman MS

更新日期：2012-09-01 00:00:00

abstract：:Advances in research and better understanding of the pathophysiology of diseases have resulted in an increase in the number of available health interventions that compete for finite public resources. Explicit choices must therefore be made about funding. ...

journal_title：Expert review of neurotherapeutics

authors： Kobelt G

更新日期：2013-12-01 00:00:00

abstract：:Understanding of the structure and function of the endocannabinoid system is rapidly evolving. Physiological and pharmacological manipulations based on cannabinoid receptors, ligands and endocannabinoids have explained some medicinal attributes of cannabinoids as used across the world for thousands of years. Plant-der...

journal_title：Expert review of neurotherapeutics

authors： Holdcroft A,Patel P

更新日期：2001-09-01 00:00:00

abstract：:Persistent gait deficits after stroke can cause falls, elevated energy cost and poor endurance. Coordination impairment is an underlying cause of gait deficits. Few efficacious interventions have been described that have targeted and measured restoration of coordinated gait components. Neuromuscular electrical stimula...

journal_title：Expert review of neurotherapeutics

authors： Daly JJ

更新日期：2006-10-01 00:00:00

abstract：:Hypertension is an important risk factor for stroke. The latter results in disability and premature death and represents a major public health problem. Various studies have established a strong relationship between increasing blood pressure and stroke risk, as well as clear evidence of a reduction in the incidence of ...

journal_title：Expert review of neurotherapeutics

authors： Karthikeyan VJ,Lip GY

更新日期：2006-02-01 00:00:00

abstract：:Introduction: Cognitive impairment and behavioral disturbances are common findings in Parkinson's disease (PD). Despite initially being considered late complications of the disease, it is currently accepted that almost all PD patients will exhibit cognitive and behavioral abnormalities from the early and even the prem...

journal_title：Expert review of neurotherapeutics

authors： Martinez-Horta S,Horta-Barba A,Kulisevsky J

更新日期：2019-07-01 00:00:00

abstract：UNLABELLED:Pediatric bipolar disorder (PBD) presents with severe affect dysregulation characterized by elated mood, irritability and depressive symptoms, often in the form of a mixed episode. Early recognition of the external clinical features and the underlying emotional processing circuitry will help us understand th...

journal_title：Expert review of neurotherapeutics

authors： Pavuluri MN,Passarotti A

更新日期：2008-09-01 00:00:00

abstract：:Background: Triptanophobia is the excessive and inadequately justified concern about potential risks of triptans. We evaluated causes and consequences of nonuse of triptans in chronic migraine (CM) Methods: Case-control study. We included CM patients firstly referred to aheadache unit. Patients were cases or controls ...

journal_title：Expert review of neurotherapeutics

authors： Martínez-Pías E,García-Azorín D,Minguez-Olaondo A,Trigo J,Sierra Á,Ruiz M,Guerrero ÁL

更新日期：2021-01-01 00:00:00

abstract：:Attention-deficit/hyperactivity disorder (ADHD) is a commonly occurring behavioral disorder among children. Community-based physicians are often the primary providers of services for children with ADHD. A set of consensus guidelines has been published by the American Academy of Pediatrics that provides best-practice d...

journal_title：Expert review of neurotherapeutics

authors： Langberg JM,Brinkman WB,Lichtenstein PK,Epstein JN

更新日期：2009-04-01 00:00:00

abstract：:Epilepsy is one of the most common neurologic disorders in childhood that often requires long term treatment with antiepileptic drugs. Both antiepileptic treatment and the comorbidities associated with epilepsy have a negative impact on bone health in growing children. Given the fact that vitamin D deficiency is a maj...

journal_title：Expert review of neurotherapeutics

authors： Cebeci AN,Ekici B

更新日期：2014-05-01 00:00:00

abstract：:This article reviews the potential uses of complementary and alternative medicine (CAM) techniques for individuals with mood disorders. Mood disorders are among the most prevalent mental health issues today and there are many approaches towards their management. While many different types of medication are available, ...

journal_title：Expert review of neurotherapeutics

authors： Moss AS,Monti DA,Amsterdam JD,Newberg AB

更新日期：2011-07-01 00:00:00

abstract：:Alzheimer's disease is an age-related dementia and its incidence is rising in developed countries as the population ages. Amyloid plaques and tau-rich neurofibrillary tangles are pathologic hallmarks of the disease. Treatment is symptomatic, consisting of compounds that block enzymatic acetylcholine degradation (acety...

journal_title：Expert review of neurotherapeutics

authors： Silverberg GD,Mayo M,Saul T,Carvalho J,McGuire D

更新日期：2004-01-01 00:00:00

abstract：:Sumatriptan subcutaneous administration is the fastest and most effective of the triptans for relief of acute migraine headache. This occurs even when the patient has already developed symptoms related to central sensitization, a key parameter in determining the effectiveness of these agents. In patients whose migrain...

journal_title：Expert review of neurotherapeutics

authors： Freitag FG

更新日期：2011-04-01 00:00:00

abstract：:Pseudotumor cerebri (PTC) is characterized by intracranial hypertension without ventriculomegaly, in the absence of a mass lesion or meningeal process. When there is no secondary cause, it is termed 'idiopathic intracranial hypertension'. Headache is the most common symptom of PTC, present in over 90% of patients. The...

journal_title：Expert review of neurotherapeutics

authors： Friedman DI

更新日期：2008-03-01 00:00:00

abstract：:The term cervicogenic headache (CeH) describes a syndrome originating from the cervical spine. There are a variety of therapeutic approaches used for the management of CeH, but scientific evidence of their effectiveness is scarce. No medication drug has proven to be effective. The evidence for greater occipital nerve ...

journal_title：Expert review of neurotherapeutics

authors： Fernández-de-las-Peñas C,Cuadrado ML

更新日期：2014-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common cause of dementia and is characterized by an insidious onset and slow deterioration in cognition, activities of daily living (ADL), mood stability and social functioning. The cholinesterase inhibitors (ChEIs), developed based on the cholinergic hypothesis, are currently cons...

journal_title：Expert review of neurotherapeutics

authors： Tsuno N

更新日期：2009-05-01 00:00:00

abstract：:Cerebral folate deficiency is defined as any neurological condition associated with low cerebrospinal fluid folate concentrations. It is becoming increasingly associated with several neurological diseases, either genetic or environmental. Treatment of cerebral folate deficiency by folate supplementation is generally e...

journal_title：Expert review of neurotherapeutics

authors： Molero-Luis M,Serrano M,O'Callaghan MM,Sierra C,Pérez-Dueñas B,García-Cazorla A,Artuch R

更新日期：2015-01-01 00:00:00