Neuromodulation for central pain.

abstract：:Genetic imaging has become an increasingly popular tool that utilizes neuroimaging techniques to investigate the impact of genetic variation on the structure, function and connectivity of the brain. Combining genetic and neuroimaging domains is a promising approach to further the understanding of the neural mechanisms...

journal_title：Expert review of neurotherapeutics

authors： Redpath HL,Lawrie SM,Sprooten E,Whalley HC,McIntosh AM,Hall J

更新日期：2013-01-01 00:00:00

abstract：:Introduction: Alzheimer's disease (AD), a commonly encountered neurodegenerative disorder, causes cognitive decline and has a devastating effect on the quality of life. AD occurs mainly through abnormal amyloid β peptide (Aβ) and tau protein (tau) activity around/in neurons. Aβ-based therapeutic techniques have been s...

journal_title：Expert review of neurotherapeutics

authors： Kuo YC,Rajesh R

更新日期：2019-07-01 00:00:00

abstract：:Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) commonly co-occur. With the DSM-5, clinicians are permitted to make an ASD diagnosis in the context of ADHD. In earlier versions of the DSM, this was not acceptable. Both ASD and ADHD are reported to have had substantial increases in pr...

journal_title：Expert review of neurotherapeutics

authors： Antshel KM,Zhang-James Y,Wagner KE,Ledesma A,Faraone SV

更新日期：2016-01-01 00:00:00

abstract：:Intraoral splints are effective in migraine prevention. In this review, changes in the quality of life of migraineurs treated with a palatal nonoccluding splint were measured. Using the Migraine Specific Quality of Life Instrument (Version 2.1), it was found that the palatal nonoccluding splint significantly improved ...

journal_title：Expert review of neurotherapeutics

authors： Shevel E

更新日期：2005-05-01 00:00:00

abstract：:Schizophrenia is a debilitating and pervasive mental illness with devastating effects on psychological, cognitive and social wellbeing, and for which current treatment options are far from ideal. Gender differences and the influence of the female reproductive life cycle on the onset, course and symptoms of schizophren...

journal_title：Expert review of neurotherapeutics

authors： Kulkarni J,Gavrilidis E,Hayes E,Heaton V,Worsley R

更新日期：2012-07-01 00:00:00

abstract：:Introduction: Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system and a global public health problem. However, its diagnosis is complicated since histological demonstration of the parasite is often not feasible, clinical manifestations are nonspecific, most neuroimaging findi...

journal_title：Expert review of neurotherapeutics

authors： Del Brutto OH

更新日期：2020-02-01 00:00:00

abstract：:Stroke is the third leading cause of mortality in the USA and one of the leading causes of severe morbidity. It is important to provide stroke patients and physicians with the most accurate prognostic information to optimize care and allocation of healthcare resources. Reliable prognostic markers available during the ...

journal_title：Expert review of neurotherapeutics

authors： Katan M,Elkind MS

更新日期：2011-02-01 00:00:00

abstract：:Recent evidence suggests that active trigger points (TrPs) in neck and shoulder muscles contribute to tension-type headache. Active TrPs within the suboccipital, upper trapezius, sternocleidomastoid, temporalis, superior oblique and lateral rectus muscles have been associated with chronic and episodic tension-type hea...

journal_title：Expert review of neurotherapeutics

authors： Alonso-Blanco C,de-la-Llave-Rincón AI,Fernández-de-las-Peñas C

更新日期：2012-03-01 00:00:00

abstract：:Introduction: Tardive dyskinesia (TD) is a hyperkinetic movement disorder that arises as a complication of exposure to dopamine receptor blocking agents. Vesicular monoamine transporter type 2 (VMAT2) inhibitors reduce dyskinesia by decreasing transport of monoamines, including dopamine, into presynaptic vesicles, lea...

journal_title：Expert review of neurotherapeutics

authors： Dorfman BJ,Jimenez-Shahed J

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Calcitonin Gene-Related Peptide (CGRP) has gradually emerged as a suitable therapeutic target to treat migraine. Considering the social and economic burden of migraine, it is fundamental to optimize the disease management with efficacious and safe treatments. In this scenario, drugs targeting GCRP, monoclo...

journal_title：Expert review of neurotherapeutics

authors： De Matteis E,Guglielmetti M,Ornello R,Spuntarelli V,Martelletti P,Sacco S

更新日期：2020-06-01 00:00:00

abstract：:Introduction: Headache is the fifth most common reason to visit an emergency department (ED). In most of the cases, headache is benign and has a primary origin, with migraine as the most common diagnosis. Inappropriate use of ED for non-emergency conditions causes overcrowding, unnecessary testing, and increased medic...

journal_title：Expert review of neurotherapeutics

authors： Luciani M,Negro A,Spuntarelli V,Bentivegna E,Martelletti P

更新日期：2021-01-04 00:00:00

abstract：:Temozolomide-based chemotherapy represents an incremental improvement in the treatment of patients with high-grade gliomas. Notwithstanding a survival benefit in a subset of patients with high-grade gliomas, temozolomide (TMZ; Temodar®, Schering-Plough Pharmaceuticals, NJ, USA) is the primarily palliative treatment fo...

journal_title：Expert review of neurotherapeutics

authors： Chamberlain MC

更新日期：2010-10-01 00:00:00

abstract：:Introduction: Paroxysmal dyskinesias and episodic ataxias are often caused by mutations in genes related to cell membrane and synaptic function. Despite the exponential increase in publications of genetically confirmed cases, management remains largely clinical based on non-systematic evidence. Areas covered: The auth...

journal_title：Expert review of neurotherapeutics

authors： De Gusmao CM,Silveira-Moriyama L

更新日期：2019-09-01 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a common behavioral disorder of a complex nature. Genetic and environmental factors are thought to be involved in precipitating the disorder. Pharmacological, animal model and recent molecular studies support the role of genes (of minor or medium effect) from dopamine...

journal_title：Expert review of neurotherapeutics

authors： Hawi Z,Kirley A,Lowe N,Fitzgerald M,Gill M

更新日期：2003-07-01 00:00:00

abstract：:Introduction: Despite increased interest in the pharmacotherapy of bipolar disorder during pregnancy and the postpartum period, management of the disorder during these critical periods in a woman's life remains challenging.Areas covered: The authors review the effect of pregnancy and the postpartum period on the cours...

journal_title：Expert review of neurotherapeutics

authors： Sharma V,Sharma P,Sharma S

更新日期：2020-04-01 00:00:00

abstract：:Generalized anxiety disorder is characterized by excessive chronic anxiety in association with many somatic symptoms. The disorder has pervasive effects on quality of life, including work, social and educational aspects and requires long-term therapy. Available studies in patients are the Diagnostic and Statistical Ma...

journal_title：Expert review of neurotherapeutics

authors： Struzik L,Vermani M,Coonerty-Femiano A,Katzman MA

更新日期：2004-03-01 00:00:00

abstract：:Natalizumab is an α-4 integrin antagonist used for the treatment of relapsing multiple sclerosis (MS). Concerns with the drug have a risen owing to a heightened risk of progressive multifocal leukoencephalopathy, which has caused some physicians to interrupt or stop treatment altogether. The article under review evalu...

journal_title：Expert review of neurotherapeutics

authors： Schaaf SM,Pitt D,Racke MK

更新日期：2011-09-01 00:00:00

abstract：:The term cervicogenic headache (CeH) describes a syndrome originating from the cervical spine. There are a variety of therapeutic approaches used for the management of CeH, but scientific evidence of their effectiveness is scarce. No medication drug has proven to be effective. The evidence for greater occipital nerve ...

journal_title：Expert review of neurotherapeutics

authors： Fernández-de-las-Peñas C,Cuadrado ML

更新日期：2014-01-01 00:00:00

abstract：:Over the last decade, much progress has been made towards identifying risk factors for schizophrenia. It is now thought that many genes of small effect contribute towards risk of developing schizophrenia and some of these probably confer susceptibility to environmental factors. Large population-based studies, using re...

journal_title：Expert review of neurotherapeutics

authors： Boydell J

更新日期：2001-11-01 00:00:00

abstract：:Introduction: Vitamin B6 dependent epilepsies are a group of treatable diseases (ALDH7A1 deficiency, PNPO deficiency, PLP binding protein deficiency, hyperprolinaemia type II and hypophosphatasia and glycosylphosphatidylinositol anchor synthesis defects) responding to pyridoxine or pyridoxal-5I-phosphate. Areas covere...

journal_title：Expert review of neurotherapeutics

authors： Mastrangelo M,Cesario S

更新日期：2019-11-01 00:00:00

abstract：:Management issues for patients with brain tumors include peritumoral edema, symptomatic seizures, venous thromboembolism, headache, pain, fatigue and neuropsychological complaints. Vasogenic edema is typically ameliorated with the lowest dose possible of corticosteroid. Seizures are managed with attention to additiona...

journal_title：Expert review of neurotherapeutics

authors： Daly FN,Schiff D

更新日期：2007-10-01 00:00:00

abstract：:The prevalence rate of chronic pain is 15% to 25% in adults while the therapeutic arsenal is still insufficient, especially in relieving neuropathic pain. Peripheral pain transmission is conducted by the small Aδ and C sensory nerve fibres. They express elements from the renin-angiotensin-aldosterone system (RAAS), a ...

journal_title：Expert review of neurotherapeutics

authors： Bessaguet F,Magy L,Desmoulière A,Demiot C

更新日期：2016-01-01 00:00:00

abstract：:Narcolepsy is a life-long neurodegenerative disorder that causes considerable impairment to quality of life. Until the 1970s, the treatment for one of the main symptoms, excessive daytime sleepiness, was restricted to stimulants, whereas the second core symptom, cataplexy, was treated with antidepressants, and the res...

journal_title：Expert review of neurotherapeutics

authors： Mayer G

更新日期：2012-05-01 00:00:00

abstract：:Introduction: Cognitive impairment and behavioral disturbances are common findings in Parkinson's disease (PD). Despite initially being considered late complications of the disease, it is currently accepted that almost all PD patients will exhibit cognitive and behavioral abnormalities from the early and even the prem...

journal_title：Expert review of neurotherapeutics

authors： Martinez-Horta S,Horta-Barba A,Kulisevsky J

更新日期：2019-07-01 00:00:00

abstract：:Patients with von Hippel-Lindau disease (VHL) often harbor significant disease burden within the CNS, specifically craniospinal-axis hemangioblastomas and endolymphatic sac tumors (ELSTs). The majority (60-80%) of patients with VHL harbor hemangioblastomas, and 10-15% will develop ELSTs. Advances in the understanding ...

journal_title：Expert review of neurotherapeutics

authors： Wind JJ,Lonser RR

更新日期：2011-10-01 00:00:00

abstract：:The risk of recurrent stroke following transient ischemic attack or minor stroke has recently been shown to be 5-10% at 1 week and 10-20% at 3 months, depending on study population and methods. This is considerably higher than previously estimated and current clinical guidelines reflect the need for rapid assessment a...

journal_title：Expert review of neurotherapeutics

authors： Giles MF,Rothwell PM

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:The role of EEG in neonatal seizure detection is well-established, being the multichannel video-EEG the gold standard. However, in the clinical practice often amplitude integrated EEG (aEEG) is used, in order to overcome the difficulties related to EEG use. Areas covered: An overview regarding neonatal sei...

journal_title：Expert review of neurotherapeutics

authors： Pisani F,Pavlidis E

更新日期：2018-02-01 00:00:00

abstract：:The spectrum of idiopathic inflammatory-demyelinating disorders of the CNS is classified based on clinical symptoms and signs, clinical severity, lesion distribution, neuroimaging features and cerebrospinal fluid characteristics. There is a wide variety of conditions in this broad spectrum. In some cases, the dissemin...

journal_title：Expert review of neurotherapeutics

authors： Idiman E,Ozakbaş S

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Neurodegenerative processes occur from the beginning of multiple sclerosis, contribute to irreversible clinical disability and are only partially addressed by current disease-modifying therapies. Reliable quantification of neuro-axonal damage may contribute to improve the assessment of disease activity and...

journal_title：Expert review of neurotherapeutics

authors： Preziosa P,Rocca MA,Filippi M

更新日期：2020-08-01 00:00:00

abstract：:Spontaneous (non-traumatic) symptomatic intracerebral hemorrhage is a devastating form of stroke, with very high overall mortality and morbidity. Even with the best current medical or surgical treatment, outcomes still remain poor. By contrast with ischemic stroke, the incidence of intracerebral hemorrhage is not decr...

journal_title：Expert review of neurotherapeutics

authors： Wilson D,Charidimou A,Werring DJ

更新日期：2014-06-01 00:00:00