Protein subcellular relocalization in the evolution of yeast singleton and duplicate genes.

Abstract:

:Gene duplication is the primary source of new genes, but the mechanisms underlying the functional divergence and retention of duplicate genes are not well understood. Because eukaryotic proteins are localized to subcellular structures and localization can be altered by a single amino acid replacement, it was recently proposed that protein subcellular relocalization (PSR) plays an important role in the functional divergence and retention of duplicate genes. Although numerous examples of distinct subcellular localizations of paralogous proteins have been reported, it is unknown whether PSR occurs more frequently after gene duplication than without duplication. By analyzing experimentally determined and computationally predicted genome-wide protein subcellular localization data of the budding yeast Saccharomyces cerevisiae and two other fungi (Schizosaccharomyces pombe and Kluyveromyces waltii), we show that even singleton genes have an appreciable rate of relocalization in evolution and that duplicate genes do not relocalize more frequently than singletons. These results suggest that subcellular relocalization is unlikely to have been a major mechanism for duplicate gene retention and functional divergence at the genomic scale.

journal_name

Genome Biol Evol

authors

Qian W,Zhang J

doi

10.1093/gbe/evp021

subject

Has Abstract

pub_date

2009-07-22 00:00:00

pages

198-204

issn

1759-6653

journal_volume

1

pub_type

信件
  • Getting a full dose? Reconsidering sex chromosome dosage compensation in the silkworm, Bombyx mori.

    abstract::Dosage compensation--equalizing gene expression levels in response to differences in gene dose or copy number--is classically considered to play a critical role in the evolution of heteromorphic sex chromosomes. As the X and Y diverge through degradation and gene loss on the Y (or the W in female-heterogametic ZW taxa...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evr036

    authors: Walters JR,Hardcastle TJ

    更新日期:2011-01-01 00:00:00

  • Concordant Changes in Gene Expression and Nucleotides Underlie Independent Adaptation to Hydrogen-Sulfide-Rich Environments.

    abstract::The colonization of novel environments often involves changes in gene expression, protein coding sequence, or both. Studies of how populations adapt to novel conditions, however, often focus on only one of these two processes, potentially missing out on the relative importance of different parts of the evolutionary pr...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy198

    authors: Brown AP,Arias-Rodriguez L,Yee MC,Tobler M,Kelley JL

    更新日期:2018-11-01 00:00:00

  • MetaSINEs: Broad Distribution of a Novel SINE Superfamily in Animals.

    abstract::SINEs (short interspersed elements) are transposable elements that typically originate independently in each taxonomic clade (order/family). However, some SINE families share a highly similar central sequence and are thus categorized as a SINE superfamily. Although only four SINE superfamilies (CORE-SINEs, V-SINEs, De...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw029

    authors: Nishihara H,Plazzi F,Passamonti M,Okada N

    更新日期:2016-02-12 00:00:00

  • Contrasting Patterns of Evolutionary Diversification in the Olfactory Repertoires of Reptile and Bird Genomes.

    abstract::Olfactory receptors (ORs) are membrane proteins that mediate the detection of odorants in the environment, and are the largest vertebrate gene family. Comparative studies of mammalian genomes indicate that OR repertoires vary widely, even between closely related lineages, as a consequence of frequent OR gains and loss...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw013

    authors: Vandewege MW,Mangum SF,Gabaldón T,Castoe TA,Ray DA,Hoffmann FG

    更新日期:2016-02-09 00:00:00

  • Measuring transcription factor-binding site turnover: a maximum likelihood approach using phylogenies.

    abstract::A major mode of gene expression evolution is based on changes in cis-regulatory elements (CREs) whose function critically depends on the presence of transcription factor-binding sites (TFBS). Because CREs experience extensive TFBS turnover even with conserved function, alignment-based studies of CRE sequence evolution...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evp010

    authors: Otto W,Stadler PF,López-Giraldéz F,Townsend JP,Lynch VJ,Wagner GP

    更新日期:2009-05-25 00:00:00

  • Evolutionary Relationships among Extinct and Extant Sloths: The Evidence of Mitogenomes and Retroviruses.

    abstract::Macroevolutionary trends exhibited by retroviruses are complex and not entirely understood. The sloth endogenized foamy-like retrovirus (SloEFV), which demonstrates incongruence in virus-host evolution among extant sloths (Order Folivora), has not been investigated heretofore in any extinct sloth lineages and its prem...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw023

    authors: Slater GJ,Cui P,Forasiepi AM,Lenz D,Tsangaras K,Voirin B,de Moraes-Barros N,MacPhee RD,Greenwood AD

    更新日期:2016-02-14 00:00:00

  • Attenuated virulence and genomic reductive evolution in the entomopathogenic bacterial symbiont species, Xenorhabdus poinarii.

    abstract::Bacteria of the genus Xenorhabdus are symbionts of soil entomopathogenic nematodes of the genus Steinernema. This symbiotic association constitutes an insecticidal complex active against a wide range of insect pests. Unlike other Xenorhabdus species, Xenorhabdus poinarii is avirulent when injected into insects in the ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu119

    authors: Ogier JC,Pagès S,Bisch G,Chiapello H,Médigue C,Rouy Z,Teyssier C,Vincent S,Tailliez P,Givaudan A,Gaudriault S

    更新日期:2014-06-05 00:00:00

  • Recurrent Loss, Horizontal Transfer, and the Obscure Origins of Mitochondrial Introns in Diatoms (Bacillariophyta).

    abstract::We sequenced mitochondrial genomes from five diverse diatoms (Toxarium undulatum, Psammoneis japonica, Eunotia naegelii, Cylindrotheca closterium, and Nitzschia sp.), chosen to fill important phylogenetic gaps and help us characterize broadscale patterns of mitochondrial genome evolution in diatoms. Although gene cont...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy103

    authors: Guillory WX,Onyshchenko A,Ruck EC,Parks M,Nakov T,Wickett NJ,Alverson AJ

    更新日期:2018-06-01 00:00:00

  • Evolutionary Dynamics of Chloroplast Genomes in Low Light: A Case Study of the Endolithic Green Alga Ostreobium quekettii.

    abstract::Some photosynthetic organisms live in extremely low light environments. Light limitation is associated with selective forces as well as reduced exposure to mutagens, and over evolutionary timescales it can leave a footprint on species' genomes. Here, we present the chloroplast genomes of four green algae (Bryopsidales...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw206

    authors: R Marcelino V,Cremen MC,Jackson CJ,Larkum AA,Verbruggen H

    更新日期:2016-10-05 00:00:00

  • Massive genomic decay in Serratia symbiotica, a recently evolved symbiont of aphids.

    abstract::All vertically transmitted bacterial symbionts undergo a process of genome reduction over time, resulting in tiny, gene-dense genomes. Comparison of genomes of ancient bacterial symbionts gives only limited information about the early stages in the transition from a free-living to symbiotic lifestyle because many chan...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evr002

    authors: Burke GR,Moran NA

    更新日期:2011-01-01 00:00:00

  • Comparative Genomics of Pathogenic and Nonpathogenic Beetle-Vectored Fungi in the Genus Geosmithia.

    abstract::Geosmithia morbida is an emerging fungal pathogen which serves as a model for examining the evolutionary processes behind pathogenicity because it is one of two known pathogens within a genus of mostly saprophytic, beetle-associated, fungi. This pathogen causes thousand cankers disease in black walnut trees and is vec...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx242

    authors: Schuelke TA,Wu G,Westbrook A,Woeste K,Plachetzki DC,Broders K,MacManes MD

    更新日期:2017-12-01 00:00:00

  • Whole Genome Incorporation and Epigenetic Stability in a Newly Synthetic Allopolyploid of Gynogenetic Gibel Carp.

    abstract::Allopolyploidization plays an important role in speciation, and some natural or synthetic allopolyploid fishes have been extensively applied to aquaculture. Although genetic and epigenetic inheritance and variation associated with plant allopolyploids have been well documented, the relative research in allopolyploid a...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy165

    authors: Shao GM,Li XY,Wang Y,Wang ZW,Li Z,Zhang XJ,Zhou L,Gui JF

    更新日期:2018-09-01 00:00:00

  • Highly variable recombinational landscape modulates efficacy of natural selection in birds.

    abstract::Determining the rate of protein evolution and identifying the causes of its variation across the genome are powerful ways to understand forces that are important for genome evolution. By using a multitissue transcriptome data set from great tit (Parus major), we analyzed patterns of molecular evolution between two pas...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu157

    authors: Gossmann TI,Santure AW,Sheldon BC,Slate J,Zeng K

    更新日期:2014-08-01 00:00:00

  • Two Groups of Cocirculating, Epidemic Clostridiodes difficile Strains Microdiversify through Different Mechanisms.

    abstract::Clostridiodes difficile strains from the NAPCR1/ST54 and NAP1/ST01 types have caused outbreaks despite of their notable differences in genome diversity. By comparing whole genome sequences of 32 NAPCR1/ST54 isolates and 17 NAP1/ST01 recovered from patients infected with C. difficile we assessed whether mutation, homol...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy059

    authors: Murillo T,Ramírez-Vargas G,Riedel T,Overmann J,Andersen JM,Guzmán-Verri C,Chaves-Olarte E,Rodríguez C

    更新日期:2018-03-01 00:00:00

  • Extensive Reduction of the Nuclear Pore Complex in Nucleomorphs.

    abstract::The nuclear pore complex (NPC) is a large macromolecular assembly situated within the pores of the nuclear envelope. Through interactions between its subcomplexes and import proteins, the NPC mediates the transport of molecules into and out of the nucleus and facilitates dynamic chromatin regulation and gene expressio...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz029

    authors: Irwin NAT,Keeling PJ

    更新日期:2019-03-01 00:00:00

  • Comparative Genomics of Sibling Fungal Pathogenic Taxa Identifies Adaptive Evolution without Divergence in Pathogenicity Genes or Genomic Structure.

    abstract::It has been estimated that the sister plant pathogenic fungal species Heterobasidion irregulare and Heterobasidion annosum may have been allopatrically isolated for 34-41 Myr. They are now sympatric due to the introduction of the first species from North America into Italy, where they freely hybridize. We used a compa...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv209

    authors: Sillo F,Garbelotto M,Friedman M,Gonthier P

    更新日期:2015-11-01 00:00:00

  • The Chemosensory Receptor Repertoire of a True Shark Is Dominated by a Single Olfactory Receptor Family.

    abstract::Throughout the animal kingdom chemical senses are one of the primary means by which organisms make sense of their environment. To achieve perception of complex chemosensory stimuli large repertoires of olfactory and gustatory receptors are employed in bony vertebrates, which are characterized by high evolutionary dyna...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evz002

    authors: Sharma K,Syed AS,Ferrando S,Mazan S,Korsching SI

    更新日期:2019-02-01 00:00:00

  • Selfish Mitochondrial DNA Proliferates and Diversifies in Small, but not Large, Experimental Populations of Caenorhabditis briggsae.

    abstract::Evolutionary interactions across levels of biological organization contribute to a variety of fundamental processes including genome evolution, reproductive mode transitions, species diversification, and extinction. Evolutionary theory predicts that so-called "selfish" genetic elements will proliferate when the host e...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv116

    authors: Phillips WS,Coleman-Hulbert AL,Weiss ES,Howe DK,Ping S,Wernick RI,Estes S,Denver DR

    更新日期:2015-06-24 00:00:00

  • Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets.

    abstract::It is often unavoidable to combine data from different sequencing centers or sequencing platforms when compiling data sets with a large number of individuals. However, the different data are likely to contain specific systematic errors that will appear as SNPs. Here, we devise a method to detect systematic errors in c...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy199

    authors: Mafessoni F,Prasad RB,Groop L,Hansson O,Prüfer K

    更新日期:2018-10-01 00:00:00

  • In Silico Identification of Candidate Genes for Fertility Restoration in Cytoplasmic Male Sterile Perennial Ryegrass (Lolium perenne L.).

    abstract::Perennial ryegrass (Lolium perenne L.) is widely used for forage production in both permanent and temporary grassland systems. To increase yields in perennial ryegrass, recent breeding efforts have been focused on strategies to more efficiently exploit heterosis by hybrid breeding. Cytoplasmic male sterility (CMS) is ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw047

    authors: Sykes T,Yates S,Nagy I,Asp T,Small I,Studer B

    更新日期:2017-02-01 00:00:00

  • Genome Mutational and Transcriptional Hotspots Are Traps for Duplicated Genes and Sources of Adaptations.

    abstract::Gene duplication generates new genetic material, which has been shown to lead to major innovations in unicellular and multicellular organisms. A whole-genome duplication occurred in the ancestor of Saccharomyces yeast species but 92% of duplicates returned to single-copy genes shortly after duplication. The persisting...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx085

    authors: Fares MA,Sabater-Muñoz B,Toft C

    更新日期:2017-05-01 00:00:00

  • Whole Genome Sequencing and Assembly of the Asian Honey Bee Apis dorsata.

    abstract::The Asian honey bee (Apis dorsata) is distinct from its more widely distributed cousin Apis mellifera by a few key characteristics. Most prominently, A. dorsata, nest in the open by forming a colony clustered around the honeycomb, whereas A. mellifera nest in concealed cavities. Additionally, the worker and reproducti...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz277

    authors: Oppenheim S,Cao X,Rueppel O,Krongdang S,Phokasem P,DeSalle R,Goodwin S,Xing J,Chantawannakul P,Rosenfeld JA

    更新日期:2020-01-01 00:00:00

  • The Effect of Population Bottleneck Size and Selective Regime on Genetic Diversity and Evolvability in Bacteria.

    abstract::Population bottlenecks leading to a drastic reduction of the population size are common in the evolutionary dynamics of natural populations; their occurrence is known to have implications for genome evolution due to genetic drift, the consequent reduction in genetic diversity, and the rate of adaptation. Nevertheless,...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz243

    authors: Wein T,Dagan T

    更新日期:2019-11-01 00:00:00

  • Comprehensive Genomic Analysis and Expression Profiling of the NOX Gene Families under Abiotic Stresses and Hormones in Plants.

    abstract::Plasma membrane NADPH oxidases (NOXs) are key producers of reactive oxygen species under both normal and stress conditions in plants and they form functional subfamilies. Studies of these subfamilies indicated that they show considerable evolutionary selection. We performed a comparative genomic analysis that identifi...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw035

    authors: Chang YL,Li WY,Miao H,Yang SQ,Li R,Wang X,Li WQ,Chen KM

    更新日期:2016-02-23 00:00:00

  • Mutation rates in plastid genomes: they are lower than you might think.

    abstract::Within plastid-bearing species, the mutation rate of the plastid genome is often assumed to be greater than that of the mitochondrial genome. This assumption is based on early, pioneering studies of land plant molecular evolution, which uncovered higher rates of synonymous substitution in plastid versus mitochondrial ...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evv069

    authors: Smith DR

    更新日期:2015-04-13 00:00:00

  • CRISPR System Acquisition and Evolution of an Obligate Intracellular Chlamydia-Related Bacterium.

    abstract::Recently, a new Chlamydia-related organism, Protochlamydia naegleriophila KNic, was discovered within a Naegleria amoeba. To decipher the mechanisms at play in the modeling of genomes from the Protochlamydia genus, we sequenced the full genome of Pr. naegleriophila, which includes a 2,885,090 bp chromosome and a 145,2...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw138

    authors: Bertelli C,Cissé OH,Rusconi B,Kebbi-Beghdadi C,Croxatto A,Goesmann A,Collyn F,Greub G

    更新日期:2016-08-25 00:00:00

  • Genomic evidence for the emergence and evolution of pathogenicity and niche preferences in the genus Campylobacter.

    abstract::The genus Campylobacter includes some of the most relevant pathogens for human and animal health; the continuous effort in their characterization has also revealed new species putatively involved in different kind of infections. Nowadays, the available genomic data for the genus comprise a wide variety of species with...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu195

    authors: Iraola G,Pérez R,Naya H,Paolicchi F,Pastor E,Valenzuela S,Calleros L,Velilla A,Hernández M,Morsella C

    更新日期:2014-09-04 00:00:00

  • A Novel Terminal-Repeat Retrotransposon in Miniature (TRIM) Is Massively Expressed in Echinococcus multilocularis Stem Cells.

    abstract::Taeniid cestodes (including the human parasites Echinococcus spp. and Taenia solium) have very few mobile genetic elements (MGEs) in their genome, despite lacking a canonical PIWI pathway. The MGEs of these parasites are virtually unexplored, and nothing is known about their expression and silencing. In this work, we ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv126

    authors: Koziol U,Radio S,Smircich P,Zarowiecki M,Fernández C,Brehm K

    更新日期:2015-07-01 00:00:00

  • Extensive Capsule Locus Variation and Large-Scale Genomic Recombination within the Klebsiella pneumoniae Clonal Group 258.

    abstract::Klebsiella pneumoniae clonal group (CG) 258, comprising sequence types (STs) 258, 11, and closely related variants, is associated with dissemination of the K. pneumoniae carbapenemase (KPC). Hospital outbreaks of KPC CG258 infections have been observed globally and are very difficult to treat. As a consequence, there ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv062

    authors: Wyres KL,Gorrie C,Edwards DJ,Wertheim HF,Hsu LY,Van Kinh N,Zadoks R,Baker S,Holt KE

    更新日期:2015-04-10 00:00:00

  • Phylogeny of Rieske/cytb complexes with a special focus on the Haloarchaeal enzymes.

    abstract::Rieske/cytochrome b (Rieske/cytb) complexes are proton pumping quinol oxidases that are present in most bacteria and Archaea. The phylogeny of their subunits follows closely the 16S-rRNA phylogeny, indicating that chemiosmotic coupling was already present in the last universal common ancestor of Archaea and bacteria. ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evs056

    authors: Baymann F,Schoepp-Cothenet B,Lebrun E,van Lis R,Nitschke W

    更新日期:2012-01-01 00:00:00