Attenuated virulence and genomic reductive evolution in the entomopathogenic bacterial symbiont species, Xenorhabdus poinarii.

Abstract:

:Bacteria of the genus Xenorhabdus are symbionts of soil entomopathogenic nematodes of the genus Steinernema. This symbiotic association constitutes an insecticidal complex active against a wide range of insect pests. Unlike other Xenorhabdus species, Xenorhabdus poinarii is avirulent when injected into insects in the absence of its nematode host. We sequenced the genome of the X. poinarii strain G6 and the closely related but virulent X. doucetiae strain FRM16. G6 had a smaller genome (500-700 kb smaller) than virulent Xenorhabdus strains and lacked genes encoding potential virulence factors (hemolysins, type 5 secretion systems, enzymes involved in the synthesis of secondary metabolites, and toxin-antitoxin systems). The genomes of all the X. poinarii strains analyzed here had a similar small size. We did not observe the accumulation of pseudogenes, insertion sequences or decrease in coding density usually seen as a sign of genomic erosion driven by genetic drift in host-adapted bacteria. Instead, genome reduction of X. poinarii seems to have been mediated by the excision of genomic blocks from the flexible genome, as reported for the genomes of attenuated free pathogenic bacteria and some facultative mutualistic bacteria growing exclusively within hosts. This evolutionary pathway probably reflects the adaptation of X. poinarii to specific host.

journal_name

Genome Biol Evol

authors

Ogier JC,Pagès S,Bisch G,Chiapello H,Médigue C,Rouy Z,Teyssier C,Vincent S,Tailliez P,Givaudan A,Gaudriault S

doi

10.1093/gbe/evu119

subject

Has Abstract

pub_date

2014-06-05 00:00:00

pages

1495-513

issue

6

issn

1759-6653

pii

evu119

journal_volume

6

pub_type

杂志文章
  • Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets.

    abstract::It is often unavoidable to combine data from different sequencing centers or sequencing platforms when compiling data sets with a large number of individuals. However, the different data are likely to contain specific systematic errors that will appear as SNPs. Here, we devise a method to detect systematic errors in c...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy199

    authors: Mafessoni F,Prasad RB,Groop L,Hansson O,Prüfer K

    更新日期:2018-10-01 00:00:00

  • Genome Assembly of the Common Pheasant Phasianus colchicus: A Model for Speciation and Ecological Genomics.

    abstract::The common pheasant (Phasianus colchicus) in the order Galliformes and the family Phasianidae, has 30 subspecies distributed across its native range in the Palearctic realm and has been introduced to Europe, North America, and Australia. It is an important game bird often subjected to wildlife management as well as a ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz249

    authors: Liu Y,Liu S,Zhang N,Chen,Que P,Liu N,Höglund J,Zhang Z,Wang B

    更新日期:2019-12-01 00:00:00

  • Accumulation of Deleterious Mutations in Landlocked Threespine Stickleback Populations.

    abstract::Colonization of new habitats often reduces population sizes and may result in the accumulation of deleterious mutations by genetic drift. Compared with the genomic basis for adaptation to new environments, genome-wide analysis of deleterious mutations in isolated populations remains limited. In the present study, we i...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa065

    authors: Yoshida K,Ravinet M,Makino T,Toyoda A,Kokita T,Mori S,Kitano J

    更新日期:2020-04-01 00:00:00

  • Evolutionary Remodeling of the Cell Envelope in Bacteria of the Planctomycetes Phylum.

    abstract::Bacteria of the Planctomycetes phylum have many unique cellular features, such as extensive membrane invaginations and the ability to import macromolecules. These features raise intriguing questions about the composition of their cell envelopes. In this study, we have used microscopy, phylogenomics, and proteomics to ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa159

    authors: Mahajan M,Seeger C,Yee B,Andersson SGE

    更新日期:2020-09-01 00:00:00

  • A Journey across Genomes Uncovers the Origin of Ubiquinone in Cyanobacteria.

    abstract::Ubiquinone (Q) is an isoprenoid quinone that functions as membrane electron carrier in mitochondria and bacterial organisms belonging to the alpha, beta, and gamma class of proteobacteria. The biosynthesis of Q follows various biochemical steps catalyzed by diverse proteins that are, in general, homologous in mitochon...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx225

    authors: Degli Esposti M

    更新日期:2017-11-01 00:00:00

  • Genome of the Parasitoid Wasp Diachasma alloeum, an Emerging Model for Ecological Speciation and Transitions to Asexual Reproduction.

    abstract::Parasitoid wasps are among the most speciose animals, yet have relatively few available genomic resources. We report a draft genome assembly of the wasp Diachasma alloeum (Hymenoptera: Braconidae), a host-specific parasitoid of the apple maggot fly Rhagoletis pomonella (Diptera: Tephritidae), and a developing model fo...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz205

    authors: Tvedte ES,Walden KKO,McElroy KE,Werren JH,Forbes AA,Hood GR,Logsdon JM,Feder JL,Robertson HM

    更新日期:2019-10-01 00:00:00

  • Centromere remodeling in Hoolock leuconedys (Hylobatidae) by a new transposable element unique to the gibbons.

    abstract::Gibbons (Hylobatidae) shared a common ancestor with the other hominoids only 15-18 million years ago. Nevertheless, gibbons show very distinctive features that include heavily rearranged chromosomes. Previous observations indicate that this phenomenon may be linked to the attenuated epigenetic repression of transposab...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evs048

    authors: Carbone L,Harris RA,Mootnick AR,Milosavljevic A,Martin DI,Rocchi M,Capozzi O,Archidiacono N,Konkel MK,Walker JA,Batzer MA,de Jong PJ

    更新日期:2012-01-01 00:00:00

  • Comparative Genomics of Rhodococcus equi Virulence Plasmids Indicates Host-Driven Evolution of the vap Pathogenicity Island.

    abstract::The conjugative virulence plasmid is a key component of the Rhodococcus equi accessory genome essential for pathogenesis. Three host-associated virulence plasmid types have been identified the equine pVAPA and porcine pVAPB circular variants, and the linear pVAPN found in bovine (ruminant) isolates. We recently charac...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx057

    authors: MacArthur I,Anastasi E,Alvarez S,Scortti M,Vázquez-Boland JA

    更新日期:2017-05-01 00:00:00

  • Rapid evolution of piRNA pathway in the teleost fish: implication for an adaptation to transposon diversity.

    abstract::The Piwi-interacting RNA (piRNA) pathway is responsible for germline specification, gametogenesis, transposon silencing, and genome integrity. Transposable elements can disrupt genome and its functions. However, piRNA pathway evolution and its adaptation to transposon diversity in the teleost fish remain unknown. This...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu105

    authors: Yi M,Chen F,Luo M,Cheng Y,Zhao H,Cheng H,Zhou R

    更新日期:2014-05-19 00:00:00

  • Comparative Transcriptomics across Nematode Life Cycles Reveal Gene Expression Conservation and Correlated Evolution in Adjacent Developmental Stages.

    abstract::Nematodes are highly abundant animals with diverse habitats and lifestyles. Some are free living whereas others parasitize animals or plants, and among the latter, infection abilities change across developmental stages to infect hosts and complete life cycles. To determine the relationship between transcriptome evolut...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa110

    authors: Lu MR,Lai CK,Liao BY,Tsai IJ

    更新日期:2020-07-01 00:00:00

  • Evolution of proteasome regulators in eukaryotes.

    abstract::All living organisms require protein degradation to terminate biological processes and remove damaged proteins. One such machine is the 20S proteasome, a specialized barrel-shaped and compartmentalized multicatalytic protease. The activity of the 20S proteasome generally requires the binding of regulators/proteasome a...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv068

    authors: Fort P,Kajava AV,Delsuc F,Coux O

    更新日期:2015-05-04 00:00:00

  • Intron gains and losses in the evolution of Fusarium and Cryptococcus fungi.

    abstract::The presence of spliceosomal introns in eukaryotic genes poses a major puzzle for the study of genome evolution. Intron densities vary enormously among distant lineages. However, the mechanisms driving intron gains are poorly understood and very few intron gains and losses have been documented over short evolutionary ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evs091

    authors: Croll D,McDonald BA

    更新日期:2012-01-01 00:00:00

  • Network-Based Analysis of eQTL Data to Prioritize Driver Mutations.

    abstract::In clonal systems, interpreting driver genes in terms of molecular networks helps understanding how these drivers elicit an adaptive phenotype. Obtaining such a network-based understanding depends on the correct identification of driver genes. In clonal systems, independent evolved lines can acquire a similar adaptive...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw010

    authors: De Maeyer D,Weytjens B,De Raedt L,Marchal K

    更新日期:2016-01-23 00:00:00

  • Plastid Transcript Editing across Dinoflagellate Lineages Shows Lineage-Specific Application but Conserved Trends.

    abstract::Dinoflagellates are a group of unicellular protists with immense ecological and evolutionary significance and cell biological diversity. Of the photosynthetic dinoflagellates, the majority possess a plastid containing the pigment peridinin, whereas some lineages have replaced this plastid by serial endosymbiosis with ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy057

    authors: Klinger CM,Paoli L,Newby RJ,Wang MY,Carroll HD,Leblond JD,Howe CJ,Dacks JB,Bowler C,Cahoon AB,Dorrell RG,Richardson E

    更新日期:2018-04-01 00:00:00

  • How Archiving by Freezing Affects the Genome-Scale Diversity of Escherichia coli Populations.

    abstract::In the experimental evolution of microbes such as Escherichia coli, many replicate populations are evolved from a common ancestor. Freezing a population sample supplemented with the cryoprotectant glycerol permits later analysis or restarting of an evolution experiment. Typically, each evolving population, and thus ea...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evw054

    authors: Sprouffske K,Aguilar-Rodríguez J,Wagner A

    更新日期:2016-05-09 00:00:00

  • The microevolution of V1r vomeronasal receptor genes in mice.

    abstract::Vomeronasal sensitivity is important for detecting intraspecific pheromonal cues as well as environmental odorants and is involved in mating, social interaction, and other daily activities of many vertebrates. Two large families of seven-transmembrane G-protein-coupled receptors, V1rs and V2rs, bind to various ligands...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evr039

    authors: Park SH,Podlaha O,Grus WE,Zhang J

    更新日期:2011-01-01 00:00:00

  • A broad genomic survey reveals multiple origins and frequent losses in the evolution of respiratory hemerythrins and hemocyanins.

    abstract::Hemerythrins and hemocyanins are respiratory proteins present in some of the most ecologically diverse animal lineages; however, the precise evolutionary history of their enzymatic domains (hemerythrin, hemocyanin M, and tyrosinase) is still not well understood. We survey a wide dataset of prokaryote and eukaryote gen...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evt102

    authors: Martín-Durán JM,de Mendoza A,Sebé-Pedrós A,Ruiz-Trillo I,Hejnol A

    更新日期:2013-01-01 00:00:00

  • What the X has to do with it: differences in regulatory variability between the sexes in Drosophila simulans.

    abstract::The mechanistic basis of regulatory variation and the prevailing evolutionary forces shaping that variation are known to differ between sexes and between chromosomes. Regulatory variation of gene expression can be due to functional changes within a gene itself (cis) or in other genes elsewhere in the genome (trans). T...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu060

    authors: Graze RM,McIntyre LM,Morse AM,Boyd BM,Nuzhdin SV,Wayne ML

    更新日期:2014-04-01 00:00:00

  • Genome-Wide Patterns of Gene Expression in a Wild Primate Indicate Species-Specific Mechanisms Associated with Tolerance to Natural Simian Immunodeficiency Virus Infection.

    abstract::Over 40 species of nonhuman primates host simian immunodeficiency viruses (SIVs). In natural hosts, infection is generally assumed to be nonpathogenic due to a long coevolutionary history between host and virus, although pathogenicity is difficult to study in wild nonhuman primates. We used whole-blood RNA-seq and SIV...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz099

    authors: Simons ND,Eick GN,Ruiz-Lopez MJ,Hyeroba D,Omeja PA,Weny G,Zheng H,Shankar A,Frost SDW,Jones JH,Chapman CA,Switzer WM,Goldberg TL,Sterner KN,Ting N

    更新日期:2019-06-01 00:00:00

  • Whole Genome Sequencing and Assembly of the Asian Honey Bee Apis dorsata.

    abstract::The Asian honey bee (Apis dorsata) is distinct from its more widely distributed cousin Apis mellifera by a few key characteristics. Most prominently, A. dorsata, nest in the open by forming a colony clustered around the honeycomb, whereas A. mellifera nest in concealed cavities. Additionally, the worker and reproducti...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz277

    authors: Oppenheim S,Cao X,Rueppel O,Krongdang S,Phokasem P,DeSalle R,Goodwin S,Xing J,Chantawannakul P,Rosenfeld JA

    更新日期:2020-01-01 00:00:00

  • Evolutionary Analysis of Bile Acid-Conjugating Enzymes Reveals a Complex Duplication and Reciprocal Loss History.

    abstract::To fulfill their physiological functions, bile acids are conjugated with amino acids. In humans, conjugation is catalyzed by bile acid coenzyme A: amino acid N-acyltransferase (BAAT), an enzyme with a highly conserved catalytic triad in its active site. Interestingly, the conjugated amino acids are highly variable amo...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz238

    authors: Kirilenko BM,Hagey LR,Barnes S,Falany CN,Hiller M

    更新日期:2019-11-01 00:00:00

  • The Tritryps Comparative Repeatome: Insights on Repetitive Element Evolution in Trypanosomatid Pathogens.

    abstract::The major human pathogens Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major are collectively known as the Tritryps. The initial comparative analysis of their genomes has uncovered that Tritryps share a great number of genes, but repetitive DNA seems to be extremely variable between them. However, the in-dept...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evz017

    authors: Pita S,Díaz-Viraqué F,Iraola G,Robello C

    更新日期:2019-02-01 00:00:00

  • Partial dosage compensation in Strepsiptera, a sister group of beetles.

    abstract::Sex chromosomes have evolved independently in many different taxa, and so have mechanisms to compensate for expression differences on sex chromosomes in males and females. Different clades have evolved vastly different ways to achieve dosage compensation, including hypertranscription of the single X in male Drosophila...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv008

    authors: Mahajan S,Bachtrog D

    更新日期:2015-01-18 00:00:00

  • A Study of Faster-Z Evolution in the Great Tit (Parus major).

    abstract::Sex chromosomes contribute substantially to key evolutionary processes such as speciation and adaptation. Several theories suggest that evolution could occur more rapidly on sex chromosomes, but currently our understanding of whether and how this occurs is limited. Here, we present an analysis of the great tit (Parus ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa044

    authors: Hayes K,Barton HJ,Zeng K

    更新日期:2020-03-01 00:00:00

  • Comparative Genomic Analysis of Acanthamoeba Endosymbionts Highlights the Role of Amoebae as a "Melting Pot" Shaping the Rickettsiales Evolution.

    abstract::Amoebae have been considered as a genetic "melting pot" for its symbionts, facilitating genetic exchanges of the bacteria that co-inhabit the same host. To test the "melting pot" hypothesis, we analyzed six genomes of amoeba endosymbionts within Rickettsiales, four of which belong to Holosporaceae family and two to Ca...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx246

    authors: Wang Z,Wu M

    更新日期:2017-11-01 00:00:00

  • Predicting the Stability of Homologous Gene Duplications in a Plant RNA Virus.

    abstract::One of the striking features of many eukaryotes is the apparent amount of redundancy in coding and non-coding elements of their genomes. Despite the possible evolutionary advantages, there are fewer examples of redundant sequences in viral genomes, particularly those with RNA genomes. The factors constraining the main...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw219

    authors: Willemsen A,Zwart MP,Higueras P,Sardanyés J,Elena SF

    更新日期:2016-10-12 00:00:00

  • Being Aquifex aeolicus: Untangling a hyperthermophile's checkered past.

    abstract::Lateral gene transfer (LGT) is an important factor contributing to the evolution of prokaryotic genomes. The Aquificae are a hyperthermophilic bacterial group whose genes show affiliations to many other lineages, including the hyperthermophilic Thermotogae, the Proteobacteria, and the Archaea. Previous phylogenomic an...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evt195

    authors: Eveleigh RJ,Meehan CJ,Archibald JM,Beiko RG

    更新日期:2013-01-01 00:00:00

  • Organellar Genomes from a ∼5,000-Year-Old Archaeological Maize Sample Are Closely Related to NB Genotype.

    abstract::The story of how preColumbian civilizations developed goes hand-in-hand with the process of plant domestication by Mesoamerican inhabitants. Here, we present the almost complete sequence of a mitochondrial genome and a partial chloroplast genome from an archaeological maize sample collected at the Valley of Tehuacán, ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx048

    authors: Pérez-Zamorano B,Vallebueno-Estrada M,Martínez González J,García Cook A,Montiel R,Vielle-Calzada JP,Delaye L

    更新日期:2017-04-01 00:00:00

  • Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data.

    abstract::Polyadenylation is a step of mRNA processing which is crucial for its expression and stability. The major polyadenylation signal (PAS) represents a nucleotide hexamer that adheres to the AATAAA consensus sequence. Over a half of human genes have multiple cleavage and polyadenylation sites, resulting in a great diversi...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw137

    authors: Kainov YA,Aushev VN,Naumenko SA,Tchevkina EM,Bazykin GA

    更新日期:2016-07-02 00:00:00

  • Gene Duplication and Gain in the Trematode Atriophallophorus Winterbourni Contributes to Adaptation to Parasitism.

    abstract::Gene duplications and novel genes have been shown to play a major role in helminth adaptation to a parasitic lifestyle because they provide the novelty necessary for adaptation to a changing environment, such as living in multiple hosts. Here we present the de novo sequenced and annotated genome of the parasitic trema...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evab010

    authors: Zajac N,Zoller S,Seppälä K,Moi D,Dessimoz C,Jokela J,Hartikainen H,Glover N

    更新日期:2021-01-23 00:00:00