Intron gains and losses in the evolution of Fusarium and Cryptococcus fungi.

Abstract:

:The presence of spliceosomal introns in eukaryotic genes poses a major puzzle for the study of genome evolution. Intron densities vary enormously among distant lineages. However, the mechanisms driving intron gains are poorly understood and very few intron gains and losses have been documented over short evolutionary time spans. Fungi emerged recently as excellent models to study intron evolution and "reverse splicing" was found to be a major driver of recent intron gains in a clade of ascomycete fungi. We screened a total of 38 genomes from two fungal clades important in medicine and agriculture to identify intron gains and losses both within and between species. We detected 86 and 198 variable intron positions in the Cryptococcus and Fusarium clades, respectively. Some genes underwent extensive changes in their exon-intron structure, with up to six variable intron positions per gene. We identified a very recently gained intron in a group of tomato-infecting strains belonging to the F. oxysporum species complex. In the human pathogen C. gattii, we found recent intron losses in subtypes of the species. The two studied fungal clades provided evidence for extensive changes in their exon-intron structure within and among closely related species. We show that both intronization of previously coding DNA and insertion of exogenous DNA are the major drivers of intron gains.

journal_name

Genome Biol Evol

authors

Croll D,McDonald BA

doi

10.1093/gbe/evs091

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

1148-61

issue

11

issn

1759-6653

pii

evs091

journal_volume

4

pub_type

杂志文章
  • Evidence of a Conserved Molecular Response to Selection for Increased Brain Size in Primates.

    abstract::The adaptive significance of human brain evolution has been frequently studied through comparisons with other primates. However, the evolution of increased brain size is not restricted to the human lineage but is a general characteristic of primate evolution. Whether or not these independent episodes of increased brai...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx028

    authors: Boddy AM,Harrison PW,Montgomery SH,Caravas JA,Raghanti MA,Phillips KA,Mundy NI,Wildman DE

    更新日期:2017-03-01 00:00:00

  • Protein subcellular relocalization in the evolution of yeast singleton and duplicate genes.

    abstract::Gene duplication is the primary source of new genes, but the mechanisms underlying the functional divergence and retention of duplicate genes are not well understood. Because eukaryotic proteins are localized to subcellular structures and localization can be altered by a single amino acid replacement, it was recently ...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evp021

    authors: Qian W,Zhang J

    更新日期:2009-07-22 00:00:00

  • Multifarious Evolutionary Pathways of a Nuclear RNA Editing Factor: Disjunctions in Coevolution of DOT4 and Its Chloroplast Target rpoC1eU488SL.

    abstract::Nuclear-encoded pentatricopeptide repeat (PPR) proteins are site-specific factors for C-to-U RNA editing in plant organelles coevolving with their targets. Losing an editing target by C-to-T conversion allows for eventual loss of its editing factor, as recently confirmed for editing factors CLB19, CRR28, and RARE1 tar...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz032

    authors: Hein A,Brenner S,Knoop V

    更新日期:2019-03-01 00:00:00

  • First ancient mitochondrial human genome from a prepastoralist southern African.

    abstract::The oldest contemporary human mitochondrial lineages arose in Africa. The earliest divergent extant maternal offshoot, namely haplogroup L0d, is represented by click-speaking forager peoples of southern Africa. Broadly defined as Khoesan, contemporary Khoesan are today largely restricted to the semidesert regions of N...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu202

    authors: Morris AG,Heinze A,Chan EK,Smith AB,Hayes VM

    更新日期:2014-09-10 00:00:00

  • Palindromic genes in the linear mitochondrial genome of the nonphotosynthetic green alga Polytomella magna.

    abstract::Organelle DNA is no stranger to palindromic repeats. But never has a mitochondrial or plastid genome been described in which every coding region is part of a distinct palindromic unit. While sequencing the mitochondrial DNA of the nonphotosynthetic green alga Polytomella magna, we uncovered precisely this type of geni...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evt122

    authors: Smith DR,Hua J,Archibald JM,Lee RW

    更新日期:2013-01-01 00:00:00

  • Highly variable recombinational landscape modulates efficacy of natural selection in birds.

    abstract::Determining the rate of protein evolution and identifying the causes of its variation across the genome are powerful ways to understand forces that are important for genome evolution. By using a multitissue transcriptome data set from great tit (Parus major), we analyzed patterns of molecular evolution between two pas...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu157

    authors: Gossmann TI,Santure AW,Sheldon BC,Slate J,Zeng K

    更新日期:2014-08-01 00:00:00

  • Genomic Analysis of Wolbachia from Laodelphax striatellus (Delphacidae, Hemiptera) Reveals Insights into Its "Jekyll and Hyde" Mode of Infection Pattern.

    abstract::Wolbachia is a widely distributed intracellular bacterial endosymbiont among invertebrates. The wStriCN, the Wolbachia strain that naturally infects an agricultural pest Laodelphax striatellus, has a "Jekyll and Hyde" mode of infection pattern with positive and negative effects: It not only kills many offspring by ind...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa006

    authors: Bing XL,Zhao DS,Sun JT,Zhang KJ,Hong XY

    更新日期:2020-02-01 00:00:00

  • The Role of microRNAs in the Repeated Parallel Diversification of Lineages of Midas Cichlid Fish from Nicaragua.

    abstract::Cichlid fishes are an ideal model system for studying biological diversification because they provide textbook examples of rapid speciation. To date, there has been little focus on the role of gene regulation during cichlid speciation. However, in recent years, gene regulation has been recognized as a powerful force l...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw097

    authors: Franchini P,Xiong P,Fruciano C,Meyer A

    更新日期:2016-06-03 00:00:00

  • Phylogenomic data support a seventh order of Methylotrophic methanogens and provide insights into the evolution of Methanogenesis.

    abstract::Increasing evidence from sequence data from various environments, including the human gut, suggests the existence of a previously unknown putative seventh order of methanogens. The first genomic data from members of this lineage, Methanomassiliicoccus luminyensis and "Candidatus Methanomethylophilus alvus," provide in...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evt128

    authors: Borrel G,O'Toole PW,Harris HM,Peyret P,Brugère JF,Gribaldo S

    更新日期:2013-01-01 00:00:00

  • Multiple Roots of Fruiting Body Formation in Amoebozoa.

    abstract::Establishment of multicellularity represents a major transition in eukaryote evolution. A subgroup of Amoebozoa, the dictyosteliids, has evolved a relatively simple aggregative multicellular stage resulting in a fruiting body supported by a stalk. Protosteloid amoeba, which are scattered throughout the amoebozoan tree...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy011

    authors: Hillmann F,Forbes G,Novohradská S,Ferling I,Riege K,Groth M,Westermann M,Marz M,Spaller T,Winckler T,Schaap P,Glöckner G

    更新日期:2018-02-01 00:00:00

  • Fine-Scale Characterization of Genomic Structural Variation in the Human Genome Reveals Adaptive and Biomedically Relevant Hotspots.

    abstract::Genomic structural variants (SVs) are distributed nonrandomly across the human genome. The "hotspots" of SVs have been implicated in evolutionary innovations, as well as medical conditions. However, the evolutionary and biomedical features of these hotspots remain incompletely understood. Here, we analyzed data from 2...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz058

    authors: Lin YL,Gokcumen O

    更新日期:2019-04-01 00:00:00

  • Insect-Symbiont Gene Expression in the Midgut Bacteriocytes of a Blood-Sucking Parasite.

    abstract::Animals interact with a diverse array of both beneficial and detrimental microorganisms. In insects, these symbioses in many cases allow feeding on nutritionally unbalanced diets. It is, however, still not clear how are obligate symbioses maintained at the cellular level for up to several hundred million years. Exact ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa032

    authors: Husnik F,Hypsa V,Darby A

    更新日期:2020-04-01 00:00:00

  • Sex Chromosome Evolution: So Many Exceptions to the Rules.

    abstract::Genomic analysis of many nonmodel species has uncovered an incredible diversity of sex chromosome systems, making it possible to empirically test the rich body of evolutionary theory that describes each stage of sex chromosome evolution. Classic theory predicts that sex chromosomes originate from a pair of homologous ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa081

    authors: Furman BLS,Metzger DCH,Darolti I,Wright AE,Sandkam BA,Almeida P,Shu JJ,Mank JE

    更新日期:2020-06-01 00:00:00

  • Studying genome heterogeneity within the arbuscular mycorrhizal fungal cytoplasm.

    abstract::Although heterokaryons have been reported in nature, multicellular organisms are generally assumed genetically homogeneous. Here, we investigate the case of arbuscular mycorrhizal fungi (AMF) that form symbiosis with plant roots. The growth advantages they confer to their hosts are of great potential benefit to sustai...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv002

    authors: Boon E,Halary S,Bapteste E,Hijri M

    更新日期:2015-01-07 00:00:00

  • Contrasting Patterns of Genomic Diversity Reveal Accelerated Genetic Drift but Reduced Directional Selection on X-Chromosome in Wild and Domestic Sheep Species.

    abstract::Analyses of genomic diversity along the X chromosome and of its correlation with autosomal diversity can facilitate understanding of evolutionary forces in shaping sex-linked genomic architecture. Strong selective sweeps and accelerated genetic drift on the X-chromosome have been inferred in primates and other model s...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy085

    authors: Chen ZH,Zhang M,Lv FH,Ren X,Li WR,Liu MJ,Nam K,Bruford MW,Li MH

    更新日期:2018-04-01 00:00:00

  • Comparative Genomics Reveals Thousands of Novel Chemosensory Genes and Massive Changes in Chemoreceptor Repertories across Chelicerates.

    abstract::Chemoreception is a widespread biological function that is essential for the survival, reproduction, and social communication of animals. Though the molecular mechanisms underlying chemoreception are relatively well known in insects, they are poorly studied in the other major arthropod lineages. Current availability o...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy081

    authors: Vizueta J,Rozas J,Sánchez-Gracia A

    更新日期:2018-04-01 00:00:00

  • Measuring transcription factor-binding site turnover: a maximum likelihood approach using phylogenies.

    abstract::A major mode of gene expression evolution is based on changes in cis-regulatory elements (CREs) whose function critically depends on the presence of transcription factor-binding sites (TFBS). Because CREs experience extensive TFBS turnover even with conserved function, alignment-based studies of CRE sequence evolution...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evp010

    authors: Otto W,Stadler PF,López-Giraldéz F,Townsend JP,Lynch VJ,Wagner GP

    更新日期:2009-05-25 00:00:00

  • Comparative Genomic Analysis of Acanthamoeba Endosymbionts Highlights the Role of Amoebae as a "Melting Pot" Shaping the Rickettsiales Evolution.

    abstract::Amoebae have been considered as a genetic "melting pot" for its symbionts, facilitating genetic exchanges of the bacteria that co-inhabit the same host. To test the "melting pot" hypothesis, we analyzed six genomes of amoeba endosymbionts within Rickettsiales, four of which belong to Holosporaceae family and two to Ca...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx246

    authors: Wang Z,Wu M

    更新日期:2017-11-01 00:00:00

  • Nephromyces Encodes a Urate Metabolism Pathway and Predicted Peroxisomes, Demonstrating That These Are Not Ancient Losses of Apicomplexans.

    abstract::The phylum Apicomplexa is a quintessentially parasitic lineage, whose members infect a broad range of animals. One exception to this may be the apicomplexan genus Nephromyces, which has been described as having a mutualistic relationship with its host. Here we analyze transcriptome data from Nephromyces and its parasi...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy251

    authors: Paight C,Slamovits CH,Saffo MB,Lane CE

    更新日期:2019-01-01 00:00:00

  • The repABC Plasmids with Quorum-Regulated Transfer Systems in Members of the Rhizobiales Divide into Two Structurally and Separately Evolving Groups.

    abstract::The large repABC plasmids of the order Rhizobiales with Class I quorum-regulated conjugative transfer systems often define the nature of the bacterium that harbors them. These otherwise diverse plasmids contain a core of highly conserved genes for replication and conjugation raising the question of their evolutionary ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv227

    authors: Wetzel ME,Olsen GJ,Chakravartty V,Farrand SK

    更新日期:2015-11-19 00:00:00

  • Phylogenomics Reveal the Dynamic Evolution of Fungal Nitric Oxide Reductases and Their Relationship to Secondary Metabolism.

    abstract::Fungi expressing P450nor, an unconventional nitric oxide (NO) reducing cytochrome P450, are considered significant contributors to environmental nitrous oxide (N2O) emissions. Despite extensive efforts, fungal contributions to N2O emissions remain uncertain. For example, the majority of N2O emitted from antibiotic-ame...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy187

    authors: Higgins SA,Schadt CW,Matheny PB,Löffler FE

    更新日期:2018-09-01 00:00:00

  • Sequence-level mechanisms of human epigenome evolution.

    abstract::DNA methylation and chromatin states play key roles in development and disease. However, the extent of recent evolutionary divergence in the human epigenome and the influential factors that have shaped it are poorly understood. To determine the links between genome sequence and human epigenome evolution, we examined t...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu142

    authors: Prendergast JG,Chambers EV,Semple CA

    更新日期:2014-06-24 00:00:00

  • The Accelerated Evolution of Lagging Strand Genes Is Independent of Sequence Context.

    abstract::We previously discovered that lagging strand genes evolve faster in Bacillus subtilis (and potentially other bacteria). Lagging strand genes are transcribed in the head-on orientation with respect to DNA replication, leading to collisions between the two machineries that stall replication and can destabilize genomes. ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw274

    authors: Merrikh CN,Weiss E,Merrikh H

    更新日期:2016-12-01 00:00:00

  • Functional shifts in insect microRNA evolution.

    abstract::MicroRNAs (miRNAs) are short endogenous RNA molecules that regulate gene expression at the posttranscriptional level and have been shown to play critical roles during animal development. The identification and comparison of miRNAs in metazoan species are therefore paramount for our understanding of the evolution of bo...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evq053

    authors: Marco A,Hui JH,Ronshaugen M,Griffiths-Jones S

    更新日期:2010-01-01 00:00:00

  • Genome-Wide Detection of Genes Under Positive Selection in Worldwide Populations of the Barley Scald Pathogen.

    abstract::Coevolution between hosts and pathogens generates strong selection pressures to maintain resistance and infectivity, respectively. Genomes of plant pathogens often encode major effect loci for the ability to successfully infect specific host genotypes. Hence, spatial heterogeneity in host genotypes coupled with abioti...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy087

    authors: Mohd-Assaad N,McDonald BA,Croll D

    更新日期:2018-04-01 00:00:00

  • Metagenomic Analysis of Fish-Associated Ca. Parilichlamydiaceae Reveals Striking Metabolic Similarities to the Terrestrial Chlamydiaceae.

    abstract::Chlamydiae are an example of obligate intracellular bacteria that possess highly reduced, compact genomes (1.0-3.5 Mbp), reflective of their abilities to sequester many essential nutrients from the host that they no longer need to synthesize themselves. The Chlamydiae is a phylum with a very wide host range spanning m...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy195

    authors: Taylor-Brown A,Pillonel T,Greub G,Vaughan L,Nowak B,Polkinghorne A

    更新日期:2018-10-01 00:00:00

  • Plastid Phylogenomic Analyses Resolve Tofieldiaceae as the Root of the Early Diverging Monocot Order Alismatales.

    abstract::The predominantly aquatic order Alismatales, which includes approximately 4,500 species within Araceae, Tofieldiaceae, and the core alismatid families, is a key group in investigating the origin and early diversification of monocots. Despite their importance, phylogenetic ambiguity regarding the root of the Alismatale...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv260

    authors: Luo Y,Ma PF,Li HT,Yang JB,Wang H,Li DZ

    更新日期:2016-04-06 00:00:00

  • Shared Signature of Recent Positive Selection on the TSBP1-BTNL2-HLA-DRA Genes in Five Native Populations from North Borneo.

    abstract::North Borneo (NB) is home to more than 40 native populations. These natives are believed to have undergone local adaptation in response to environmental challenges such as the mosquito-abundant tropical rainforest. We attempted to trace the footprints of natural selection from the genomic data of NB native populations...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evaa207

    authors: Hoh BP,Zhang X,Deng L,Yuan K,Yew CW,Saw WY,Hoque MZ,Aghakhanian F,Phipps ME,Teo YY,Subbiah VK,Xu S

    更新日期:2020-12-06 00:00:00

  • Gene-by-Gene or Localized Dosage Compensation on the Neo-X Chromosome in Drosophila miranda.

    abstract::Many organisms have a global mechanism for dosage compensation (DC) operating along the entire male X chromosome, which equalizes gene expression on the male X with that on the two Xs in females and/or on autosomes. At the initial stage of sex chromosome evolution, however, gene-by-gene (or localized) DC may also be n...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy148

    authors: Nozawa M,Ikeo K,Gojobori T

    更新日期:2018-08-01 00:00:00

  • Sex Chromosome Dosage Compensation in Heliconius Butterflies: Global yet Still Incomplete?

    abstract::The evolution of heterogametic sex chromosomes is often-but not always-accompanied by the evolution of dosage compensating mechanisms that mitigate the impact of sex-specific gene dosage on levels of gene expression. One emerging view of this process is that such mechanisms may only evolve in male-heterogametic (XY) s...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv156

    authors: Walters JR,Hardcastle TJ,Jiggins CD

    更新日期:2015-09-02 00:00:00