The Effect of Population Bottleneck Size and Selective Regime on Genetic Diversity and Evolvability in Bacteria.

abstract：:Cyanobacteria are dominant primary producers of various ecosystems and they colonize marine as well as freshwater and terrestrial habitats. On the basis of their oxygenic photosynthesis they are known to synthesize a high number of secondary metabolites, which makes them promising for biotechnological applications. St...

journal_title：Genome biology and evolution

authors： Will SE,Henke P,Boedeker C,Huang S,Brinkmann H,Rohde M,Jarek M,Friedl T,Seufert S,Schumacher M,Overmann J,Neumann-Schaal M,Petersen J

更新日期：2019-01-01 00:00:00

abstract：:Kallikrein related peptidase 8 (KLK8; also called neuropsin) is a serine protease that plays distinct roles in the skin and hippocampus. In the skin, KLK8 influences keratinocyte proliferation and desquamation, and activates antimicrobial peptides in sweat. In the hippocampus, KLK8 affects memory acquisition. Here, we...

journal_title：Genome biology and evolution

authors： Hecker N,Sharma V,Hiller M

更新日期：2017-11-01 00:00:00

abstract：:Analysis of more than 150 Clostridium botulinum Group II type E genomes identified a small fraction (6%) where neurotoxin-encoding genes were located on plasmids. Seven closely related (134-144 kb) neurotoxigenic plasmids of subtypes E1, E3, and E10 were characterized; all carried genes associated with plasmid mobilit...

journal_title：Genome biology and evolution

authors： Carter AT,Austin JW,Weedmark KA,Peck MW

更新日期：2016-03-02 00:00:00

abstract：:Over 40 species of nonhuman primates host simian immunodeficiency viruses (SIVs). In natural hosts, infection is generally assumed to be nonpathogenic due to a long coevolutionary history between host and virus, although pathogenicity is difficult to study in wild nonhuman primates. We used whole-blood RNA-seq and SIV...

journal_title：Genome biology and evolution

authors： Simons ND,Eick GN,Ruiz-Lopez MJ,Hyeroba D,Omeja PA,Weny G,Zheng H,Shankar A,Frost SDW,Jones JH,Chapman CA,Switzer WM,Goldberg TL,Sterner KN,Ting N

更新日期：2019-06-01 00:00:00

abstract：:Bacterial degraders of chlorophenoxy herbicides have been isolated from various ecosystems, including pristine environments. Among these degraders, the sphingomonads constitute a prominent group that displays versatile xenobiotic-degradation capabilities. Four separate sequencing strategies were required to provide th...

journal_title：Genome biology and evolution

authors： Nielsen TK,Rasmussen M,Demanèche S,Cecillon S,Vogel TM,Hansen LH

更新日期：2017-09-01 00:00:00

abstract：:We determined the complete mitochondrial (mt) genomes of three evaniomorph species, Ceraphron sp. (Ceraphronoidea), Gasteruption sp. (Evanioidea), and Orthogonalys pulchella (Trigonalyoidea) as well as the nearly complete mt genome from another evaniomorph species, Megalyra sp. (Megalyroidea). Each of them possesses d...

journal_title：Genome biology and evolution

authors： Mao M,Gibson T,Dowton M

更新日期：2014-07-01 00:00:00

abstract：:Clashes between transcription and replication complexes can cause point mutations and chromosome rearrangements on heavily transcribed genes. In eukaryotic ribosomal RNA genes, the system that prevents transcription-replication conflicts also causes frequent copy number variation. Such fast mutational dynamics do not ...

journal_title：Genome biology and evolution

authors： Colizzi ES,Hogeweg P

更新日期：2019-11-01 00:00:00

abstract：:Nematodes are highly abundant animals with diverse habitats and lifestyles. Some are free living whereas others parasitize animals or plants, and among the latter, infection abilities change across developmental stages to infect hosts and complete life cycles. To determine the relationship between transcriptome evolut...

journal_title：Genome biology and evolution

authors： Lu MR,Lai CK,Liao BY,Tsai IJ

更新日期：2020-07-01 00:00:00

abstract：:The effect of homologous recombination (HR) on the evolution of microbial genomes remains contentious as competing hypotheses seek to explain the evolutionary dynamics of microbial species. Evidence for HR between microbial genomes is widespread, and this process has been proposed to act as a cohesive force that can c...

journal_title：Genome biology and evolution

authors： Doroghazi JR,Buckley DH

更新日期：2011-01-01 00:00:00

abstract：:Gibbons (Hylobatidae) shared a common ancestor with the other hominoids only 15-18 million years ago. Nevertheless, gibbons show very distinctive features that include heavily rearranged chromosomes. Previous observations indicate that this phenomenon may be linked to the attenuated epigenetic repression of transposab...

journal_title：Genome biology and evolution

authors： Carbone L,Harris RA,Mootnick AR,Milosavljevic A,Martin DI,Rocchi M,Capozzi O,Archidiacono N,Konkel MK,Walker JA,Batzer MA,de Jong PJ

更新日期：2012-01-01 00:00:00

abstract：:Protection against inflammation and oxidative stress is key in slowing down aging processes. The honey bee (Apis mellifera) shows flexible aging patterns linked to the social role of individual bees. One molecular factor associated with honey bee aging regulation is vitellogenin, a lipoglycophosphoprotein with anti-in...

journal_title：Genome biology and evolution

authors： Salmela H,Stark T,Stucki D,Fuchs S,Freitak D,Dey A,Kent CF,Zayed A,Dhaygude K,Hokkanen H,Sundström L

更新日期：2016-03-09 00:00:00

abstract：:The universal genetic code defines the translation of nucleotide triplets, called codons, into amino acids. In many Saccharomycetes a unique alteration of this code affects the translation of the CUG codon, which is normally translated as leucine. Most of the species encoding CUG alternatively as serine belong to the ...

journal_title：Genome biology and evolution

authors： Mühlhausen S,Kollmar M

更新日期：2014-07-22 00:00:00

abstract：:All vertically transmitted bacterial symbionts undergo a process of genome reduction over time, resulting in tiny, gene-dense genomes. Comparison of genomes of ancient bacterial symbionts gives only limited information about the early stages in the transition from a free-living to symbiotic lifestyle because many chan...

journal_title：Genome biology and evolution

authors： Burke GR,Moran NA

更新日期：2011-01-01 00:00:00

abstract：:Hantaviruses are zoonotic viruses with a complex evolutionary history of virus-host coevolution and cross-species transmission. Although hantaviruses have a broad reservoir host range, virus-host relationships were previously thought to be strict, with a single virus species infecting a single host species. Here, we d...

journal_title：Genome biology and evolution

authors： Laenen L,Vergote V,Kafetzopoulou LE,Wawina TB,Vassou D,Cook JA,Hugot JP,Deboutte W,Kang HJ,Witkowski PT,Köppen-Rung P,Krüger DH,Licková M,Stang A,Striešková L,Szemeš T,Markowski J,Hejduk J,Kafetzopoulos D,Van Ranst

更新日期：2018-01-01 00:00:00

abstract：:Aspergillus ochraceoroseus and Aspergillus rambellii were isolated from soil detritus in Taï National Park, Ivory Coast, Africa. The Type strain for each species happens to be the only representative ever sampled. Both species secrete copious amounts of aflatoxin B1 and sterigmatocystin, because each of their genomes ...

journal_title：Genome biology and evolution

authors： Moore GG,Mack BM,Beltz SB

更新日期：2015-12-03 00:00:00

abstract：:The Asian honey bee (Apis dorsata) is distinct from its more widely distributed cousin Apis mellifera by a few key characteristics. Most prominently, A. dorsata, nest in the open by forming a colony clustered around the honeycomb, whereas A. mellifera nest in concealed cavities. Additionally, the worker and reproducti...

journal_title：Genome biology and evolution

authors： Oppenheim S,Cao X,Rueppel O,Krongdang S,Phokasem P,DeSalle R,Goodwin S,Xing J,Chantawannakul P,Rosenfeld JA

更新日期：2020-01-01 00:00:00

abstract：:The genus Campylobacter includes some of the most relevant pathogens for human and animal health; the continuous effort in their characterization has also revealed new species putatively involved in different kind of infections. Nowadays, the available genomic data for the genus comprise a wide variety of species with...

journal_title：Genome biology and evolution

authors： Iraola G,Pérez R,Naya H,Paolicchi F,Pastor E,Valenzuela S,Calleros L,Velilla A,Hernández M,Morsella C

更新日期：2014-09-04 00:00:00

abstract：:Multicopy ampliconic gene families on the Y chromosome play an important role in spermatogenesis. Thus, studying their genetic variation in endangered great ape species is critical. We estimated the sizes (copy number) of nine Y ampliconic gene families in population samples of chimpanzee, bonobo, and orangutan with d...

journal_title：Genome biology and evolution

authors： Vegesna R,Tomaszkiewicz M,Ryder OA,Campos-Sánchez R,Medvedev P,DeGiorgio M,Makova KD

更新日期：2020-06-01 00:00:00

abstract：:Orphan genes are defined as genes that lack detectable similarity to genes in other species and therefore no clear signals of common descent (i.e., homology) can be inferred. Orphans are an enigmatic portion of the genome because their origin and function are mostly unknown and they typically make up 10% to 30% of all...

journal_title：Genome biology and evolution

authors： Wissler L,Gadau J,Simola DF,Helmkampf M,Bornberg-Bauer E

更新日期：2013-01-01 00:00:00

abstract：:The chloroplast is an essential plant organelle responsible for photosynthesis. Gene duplication, relocation, and loss in the chloroplast genome (cpDNA) are useful for exploring the evolution and phylogeny of plant species. In this study, the complete chloroplast genome of Paris verticillata was sequenced using the 45...

journal_title：Genome biology and evolution

authors： Do HD,Kim JS,Kim JH

更新日期：2014-06-19 00:00:00

abstract：:The genus Halomonas possesses bacteria that are halophilic or halotolerant and exhibit a wide range of pH tolerance. The genome of Halomonas sp. Soap Lake #7 was sequenced to provide a better understanding of the mechanisms for salt and pH tolerance in this genus. The bacterium's genome was found to possess two comple...

journal_title：Genome biology and evolution

authors： Mormile MR,Edwards T,Frank R,Geurin Z,Haendiges J,Hoffmann M,Miller J

更新日期：2019-06-01 00:00:00

abstract：:A major mode of gene expression evolution is based on changes in cis-regulatory elements (CREs) whose function critically depends on the presence of transcription factor-binding sites (TFBS). Because CREs experience extensive TFBS turnover even with conserved function, alignment-based studies of CRE sequence evolution...

journal_title：Genome biology and evolution

authors： Otto W,Stadler PF,López-Giraldéz F,Townsend JP,Lynch VJ,Wagner GP

更新日期：2009-05-25 00:00:00

abstract：:Gene duplication is the primary source of new genes, but the mechanisms underlying the functional divergence and retention of duplicate genes are not well understood. Because eukaryotic proteins are localized to subcellular structures and localization can be altered by a single amino acid replacement, it was recently ...

journal_title：Genome biology and evolution

authors： Qian W,Zhang J

更新日期：2009-07-22 00:00:00

abstract：:Transposable elements (TEs) are repetitive DNA sequences that can make new copies of themselves that are inserted elsewhere in a host genome. The abundance and distributions of TEs vary considerably among phylogenetically diverse hosts. With the aim of exploring the basis of this variation, we evaluated correlations b...

journal_title：Genome biology and evolution

authors： Shen JJ,Dushoff J,Bewick AJ,Chain FJ,Evans BJ

更新日期：2013-01-01 00:00:00

abstract：:Population-level differences in the number of copies of genes resulting from gene duplication and loss have recently been recognized as an important source of variation in eukaryotes. However, except for a small number of cases, the phenotypic effects of this variation are unknown. Data from the Saccharomyces Genome R...

journal_title：Genome biology and evolution

authors： Ames RM,Rash BM,Hentges KE,Robertson DL,Delneri D,Lovell SC

更新日期：2010-01-01 00:00:00

abstract：:In this study, the full genome sequence of Bacillus velezensis strain UFLA258, a biological control agent of plant pathogens was obtained, assembled, and annotated. With a comparative genomics approach, in silico analyses of all complete genomes of B. velezensis and closely related species available in the database we...

journal_title：Genome biology and evolution

authors： Silva FJ,Ferreira LC,Campos VP,Cruz-Magalhães V,Barros AF,Andrade JP,Roberts DP,de Souza JT

更新日期：2019-10-01 00:00:00

abstract：:The evolution of heterogametic sex chromosomes is often-but not always-accompanied by the evolution of dosage compensating mechanisms that mitigate the impact of sex-specific gene dosage on levels of gene expression. One emerging view of this process is that such mechanisms may only evolve in male-heterogametic (XY) s...

journal_title：Genome biology and evolution

authors： Walters JR,Hardcastle TJ,Jiggins CD

更新日期：2015-09-02 00:00:00

abstract：:The genus Claviceps has been known for centuries as an economically important fungal genera for pharmacology and agricultural research. Only recently have researchers begun to unravel the evolutionary history of the genus, with origins in South America and classification of four distinct sections through ecological, m...

journal_title：Genome biology and evolution

authors： Wyka SA,Mondo SJ,Liu M,Dettman J,Nalam V,Broders KD

更新日期：2021-01-29 00:00:00

abstract：:Because natural selection is likely to act on multiple genes underlying a given phenotypic trait, we study here the potential effect of ongoing and past selection on the genetic diversity of human biological pathways. We first show that genes included in gene sets are generally under stronger selective constraints tha...

journal_title：Genome biology and evolution

authors： Daub JT,Dupanloup I,Robinson-Rechavi M,Excoffier L

更新日期：2015-05-13 00:00:00

abstract：:The precise localization of CaV2 voltage-gated calcium channels at the synapse active zone requires various interacting proteins, of which, Rab3-interacting molecule or RIM is considered particularly important. In vertebrates, RIM interacts with CaV2 channels in vitro via a PDZ domain that binds to the extreme C-termi...

journal_title：Genome biology and evolution

authors： Piekut T,Wong YY,Walker SE,Smith CL,Gauberg J,Harracksingh AN,Lowden C,Novogradac BB,Cheng HM,Spencer GE,Senatore A

更新日期：2020-08-01 00:00:00