Abstract:
:The genus Halomonas possesses bacteria that are halophilic or halotolerant and exhibit a wide range of pH tolerance. The genome of Halomonas sp. Soap Lake #7 was sequenced to provide a better understanding of the mechanisms for salt and pH tolerance in this genus. The bacterium's genome was found to possess two complete multiple resistance and pH antiporter systems, Group 1 and Group 2. This is the first report of both multiple resistance and pH antiporter Groups 1 and 2 in the genome of a haloalkaliphilic bacterium.
journal_name
Genome Biol Evoljournal_title
Genome biology and evolutionauthors
Mormile MR,Edwards T,Frank R,Geurin Z,Haendiges J,Hoffmann M,Miller Jdoi
10.1093/gbe/evz117subject
Has Abstractpub_date
2019-06-01 00:00:00pages
1706-1709issue
6issn
1759-6653pii
5520441journal_volume
11pub_type
杂志文章abstract::DNA methylation and chromatin states play key roles in development and disease. However, the extent of recent evolutionary divergence in the human epigenome and the influential factors that have shaped it are poorly understood. To determine the links between genome sequence and human epigenome evolution, we examined t...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evu142
更新日期:2014-06-24 00:00:00
abstract::Coevolution between hosts and pathogens generates strong selection pressures to maintain resistance and infectivity, respectively. Genomes of plant pathogens often encode major effect loci for the ability to successfully infect specific host genotypes. Hence, spatial heterogeneity in host genotypes coupled with abioti...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evy087
更新日期:2018-04-01 00:00:00
abstract::Bacteria of the genus Xenorhabdus are symbionts of soil entomopathogenic nematodes of the genus Steinernema. This symbiotic association constitutes an insecticidal complex active against a wide range of insect pests. Unlike other Xenorhabdus species, Xenorhabdus poinarii is avirulent when injected into insects in the ...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evu119
更新日期:2014-06-05 00:00:00
abstract::Bartonella is a genetically diverse group of vector-borne bacteria. Over 40 species have been characterized to date, mainly from mammalian reservoirs and arthropod vectors. Rodent reservoirs harbor one of the largest Bartonella diversity described to date, and novel species and genetic variants are continuously identi...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evy236
更新日期:2018-11-01 00:00:00
abstract::Multicopy ampliconic gene families on the Y chromosome play an important role in spermatogenesis. Thus, studying their genetic variation in endangered great ape species is critical. We estimated the sizes (copy number) of nine Y ampliconic gene families in population samples of chimpanzee, bonobo, and orangutan with d...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evaa088
更新日期:2020-06-01 00:00:00
abstract::Rapid divergence of gene copies after duplication is thought to determine the fate of the copies and evolution of novel protein functions. However, data on how long the gene copies continue to experience an elevated rate of evolution remain scarce. Standard theory of gene duplications based on some level of genetic re...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evu159
更新日期:2014-07-28 00:00:00
abstract::The selective pressures acting on viruses that replicate under enhanced mutation rates are largely unknown. Here, we describe resistance of foot-and-mouth disease virus to the mutagen 5-fluorouracil (FU) through a single polymerase substitution that prevents an excess of A to G and U to C transitions evoked by FU on t...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evx075
更新日期:2017-05-01 00:00:00
abstract::Alternative splicing and gene duplication are the two main processes responsible for expanding protein functional diversity. Although gene duplication can generate new genes and alternative splicing can introduce variation through alternative gene products, the interplay between the two processes is complex and poorly...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evv076
更新日期:2015-04-29 00:00:00
abstract::We previously discovered that lagging strand genes evolve faster in Bacillus subtilis (and potentially other bacteria). Lagging strand genes are transcribed in the head-on orientation with respect to DNA replication, leading to collisions between the two machineries that stall replication and can destabilize genomes. ...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evw274
更新日期:2016-12-01 00:00:00
abstract::SHORT VEGETATIVE PHASE (SVP) genes are members of the well-known MADS-box gene family that regulates vital developmental processes in plants. In Arabidopsis, there are two SVP paralogs, SVP/AGAMOUS-LIKE22 (SVP/AGL22) and AGL24. SVP protein suppresses the flowering process, whereas AGL24 acts as a flowering activator. ...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evy235
更新日期:2018-11-01 00:00:00
abstract::Genome reduction is a hallmark of symbiotic genomes, and the rate and patterns of gene loss associated with this process have been investigated in several different symbiotic systems. However, in long-term host-associated coevolving symbiont clades, the genome size differences between strains are normally quite small ...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evv108
更新日期:2015-05-28 00:00:00
abstract::We sequenced genomes of five parasite species in family Orobanchaceae to explore the evolutionary role of horizontal gene transfer in plants. Orobanche minor and Aeginetia indica are obligate parasites with no photosynthetic activity, whereas the other three (Pedicularis keiskei, Phtheirospermum japonicum, and Melampy...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evy219
更新日期:2018-12-01 00:00:00
abstract::Plants and fungi display a broad range of interactions in natural and agricultural ecosystems ranging from symbiosis to parasitism. These ecological interactions result in coevolution between genes belonging to different partners. A well-understood example is secreted fungal effector proteins and their host targets, w...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evy023
更新日期:2018-02-01 00:00:00
abstract::Human-specific small insertions and deletions (HS indels, with lengths <100 bp) are reported to be ubiquitous in the human genome. However, whether these indels contribute to human-specific traits remains unclear. Here we employ a modified McDonald-Kreitman (MK) test and a combinatorial population genetics approach to...
journal_title:Genome biology and evolution
pub_type: 信件
doi:10.1093/gbe/evp041
更新日期:2009-10-20 00:00:00
abstract::The precise localization of CaV2 voltage-gated calcium channels at the synapse active zone requires various interacting proteins, of which, Rab3-interacting molecule or RIM is considered particularly important. In vertebrates, RIM interacts with CaV2 channels in vitro via a PDZ domain that binds to the extreme C-termi...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evaa097
更新日期:2020-08-01 00:00:00
abstract::Auxin/indole acetic acids (Aux/IAAs) and auxin response factors (ARFs), major components of the Aux signaling network, are involved in many developmental processes in plants. Investigating their evolution will provide new sight on the relationship between the molecular evolution of these genes and the increasing morph...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evv259
更新日期:2015-12-31 00:00:00
abstract::The molecular signature of selection depends strongly on whether new mutations are immediately favorable and sweep to fixation (hard sweeps) as opposed to when selection acts on segregating variation (soft sweeps). The prediction of reduced sequence variation around selected polymorphisms is much stronger for hard tha...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evt100
更新日期:2013-01-01 00:00:00
abstract::Mitochondrial evolution has given rise to a complex array of organelles, ranging from classical aerobic mitochondria to mitochondrial remnants known as hydrogenosomes and mitosomes. The latter are found in anaerobic eukaryotes, and these highly derived organelles often retain only scant evidence of their mitochondrial...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evq015
更新日期:2010-07-12 00:00:00
abstract::The ribonuclease (RNase) A superfamily is a vertebrate-specific gene family. Because of a massive expansion that occurred during the early mammalian evolution, extant mammals in general have much more RNase genes than nonmammalian vertebrates. Mammalian RNases have been associated with diverse physiological functions ...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evt161
更新日期:2013-01-01 00:00:00
abstract::Although heterokaryons have been reported in nature, multicellular organisms are generally assumed genetically homogeneous. Here, we investigate the case of arbuscular mycorrhizal fungi (AMF) that form symbiosis with plant roots. The growth advantages they confer to their hosts are of great potential benefit to sustai...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evv002
更新日期:2015-01-07 00:00:00
abstract::One of the striking features of many eukaryotes is the apparent amount of redundancy in coding and non-coding elements of their genomes. Despite the possible evolutionary advantages, there are fewer examples of redundant sequences in viral genomes, particularly those with RNA genomes. The factors constraining the main...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evw219
更新日期:2016-10-12 00:00:00
abstract::Within plastid-bearing species, the mutation rate of the plastid genome is often assumed to be greater than that of the mitochondrial genome. This assumption is based on early, pioneering studies of land plant molecular evolution, which uncovered higher rates of synonymous substitution in plastid versus mitochondrial ...
journal_title:Genome biology and evolution
pub_type: 信件
doi:10.1093/gbe/evv069
更新日期:2015-04-13 00:00:00
abstract::Epigenetic variation in natural populations with contrasting habitats might be an important element, in addition to the genetic variation, in plant adaptation to environmental stress. Here, we assessed genetic, epigenetic, and cytogenetic structure of the three Lilium bosniacum populations growing on distinct habitats...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evy010
更新日期:2018-01-01 00:00:00
abstract::Chagas disease was described by Carlos Chagas, who first identified the parasite Trypanosoma cruzi from a 2-year-old girl called Berenice. Many T. cruzi sequencing projects based on short reads have demonstrated that genome assembly and downstream comparative analyses are extremely challenging in this species, given t...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evz129
更新日期:2019-07-01 00:00:00
abstract::Retrotransposons, DNA sequences capable of creating copies of themselves, compose about half of the human genome and played a central role in the evolution of mammals. Their current position in the host genome is the result of the retrotranscription process and of the following host genome evolution. We apply a model ...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evaa201
更新日期:2020-11-03 00:00:00
abstract::Acetyl-CoA carboxylase (ACCase) is the key regulator of fatty acid biosynthesis. In most plants, ACCase exists in two locations (cytosol and plastids) and in two forms (homomeric and heteromeric). Heteromeric ACCase comprises four subunits, three of them (ACCA-C) are nuclear encoded (nr) and the fourth (ACCD) is usual...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evz059
更新日期:2019-06-01 00:00:00
abstract::The nearly neutral theory, which proposes that most mutations are deleterious or close to neutral, predicts that the ratio of nonsynonymous over synonymous substitution rates (dN/dS), and potentially also the ratio of radical over conservative amino acid replacement rates (Kr/Kc), are negatively correlated with effect...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evt083
更新日期:2013-01-01 00:00:00
abstract::The extent of genome divergence and the evolutionary events leading to speciation of marine bacteria have mostly been studied for (locally) abundant, free-living groups. The genus Phaeobacter is found on different marine surfaces, seems to occupy geographically disjunct habitats, and is involved in different biotic in...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evx249
更新日期:2017-12-01 00:00:00
abstract::Sex determination evolves rapidly, often because of turnover of the genes at the top of the pathway. The house fly, Musca domestica, has a multifactorial sex determination system, allowing us to identify the selective forces responsible for the evolutionary turnover of sex determination in action. There is a male dete...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evv128
更新日期:2015-07-02 00:00:00
abstract::The contribution of the transposons' promoter in the horizontal transfer process is quite overlooked in the scientific literature. To shed light on this aspect we have mimicked the horizontal transfer process in laboratory and assayed in a wide range of hosts (fly, human, yeast and bacteria) the promoter activity of t...
journal_title:Genome biology and evolution
pub_type: 杂志文章
doi:10.1093/gbe/evx122
更新日期:2017-06-01 00:00:00