Endosonographic TNM staging of extrahepatic bile duct cancer: comparison with pathological staging.

abstract：:The cause of Ménétrier's disease is unknown, although allergic, autoimmune, and infectious, particularly viral, causes have been postulated. This case report describes a 3-year-old child with Ménétrier's disease in whom evidence of acute cytomegalovirus (CMV) infection was found. To our knowledge, this is the first ca...

journal_title：Gastroenterology

authors： Eisenstat DD,Griffiths AM,Cutz E,Petric M,Drumm B

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND & AIMS:Quantitative neurophysiological studies have identified the presence of at least 2 spinal neuronal populations (abrupt and sustained) that are excited by the noxious visceral stimulus colorectal distention. This study examined the effects of the kappa opioid receptor agonists fedotozine and U50488H on...

journal_title：Gastroenterology

authors： Ness TJ

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND & AIMS:The liver has high regenerative potential. We attempted to establish a novel culture system for extensive expansion of fetal mouse hepatic stem/progenitor cells and to characterize cultured cells. METHODS:Hepatic spheroids collected from 6-day floating cultures were cultured on collagen-coated dishes...

journal_title：Gastroenterology

authors： Tsuchiya A,Heike T,Fujino H,Shiota M,Umeda K,Yoshimoto M,Matsuda Y,Ichida T,Aoyagi Y,Nakahata T

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND & AIMS:Human tumors and liver cancer cell lines express the product of a fusion between the first 13 exons in the mannosidase α class 2A member 1 gene (MAN2A1) and the last 6 exons in the FER tyrosine kinase gene (FER), called MAN2A1-FER. We investigated whether MAN2A1-FER is expressed by human liver tumors ...

journal_title：Gastroenterology

authors： Chen ZH,Yu YP,Tao J,Liu S,Tseng G,Nalesnik M,Hamilton R,Bhargava R,Nelson JB,Pennathur A,Monga SP,Luketich JD,Michalopoulos GK,Luo JH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND/AIMS:Familial adenomatous polyposis is caused by germline mutation of the adenomatous polyposis coli (APC) gene. Affected individuals develop hundreds of colorectal adenomas at young age and can have extracolonic lesions. METHODS:This study evaluated the phenotype of 74 patients with familial adenomatous po...

journal_title：Gastroenterology

authors： Giardiello FM,Krush AJ,Petersen GM,Booker SV,Kerr M,Tong LL,Hamilton SR

更新日期：1994-06-01 00:00:00

abstract：:Plasma amino acid abnormalities are common in alcoholics, but the respective role of alcoholism, nutrition, and liver injury in producing these abnormalities is unknown. To elucidate this question, amino acids were measured in 56 alcoholics and 32 nonalcoholics with liver disease, and in an experimental model of alcoh...

journal_title：Gastroenterology

authors： Shaw S,Lieber CS

更新日期：1978-04-01 00:00:00

abstract：:We have analyzed the frequency of chronicity and its distribution according to epidemiologic background following acute non-A, non-B hepatitis. Eighteen of 45 cases (40%) developed chronic liver disease. The incidence of chronicity was significantly higher following transfusion and among drug addicts (54% and 58%) tha...

journal_title：Gastroenterology

authors： Rakela J,Redeker AG

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic hepatitis C virus infection activates an intrahepatic immune response, leading to increased expression of interferon (IFN)-stimulated genes and activation of natural killer (NK) cells-the most prevalent innate immune cell in the liver. We investigated whether the elimination of hepatitis C vir...

journal_title：Gastroenterology

authors： Serti E,Chepa-Lotrea X,Kim YJ,Keane M,Fryzek N,Liang TJ,Ghany M,Rehermann B

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND/AIMS:Despite putative roles of calcium in biliary physiology and gallstone formation, quantitative aspects of calcium binding to bile salt (BS) monomers, simple micelles, mixed micelles, and vesicles, which constitute the lipid aggregates in bile, remain unexplored. METHODS:Calcium activity was measured usi...

journal_title：Gastroenterology

authors： Donovan JM,Leonard MR,Batta AK,Carey MC

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND & AIMS:Conventional transarterial chemoembolization (cTACE) is used to treat patients with hepatocellular carcinoma (HCC). Radioembolization is a minimally invasive procedure that involves implantation of radioactive micron-sized particles loaded with yttrium-90 (Y90) inside the blood vessels that supply a t...

journal_title：Gastroenterology

authors： Salem R,Gordon AC,Mouli S,Hickey R,Kallini J,Gabr A,Mulcahy MF,Baker T,Abecassis M,Miller FH,Yaghmai V,Sato K,Desai K,Thornburg B,Benson AB,Rademaker A,Ganger D,Kulik L,Lewandowski RJ

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND & AIMS:Little is known about the prevalence of nonalcoholic fatty liver disease (NAFLD) among severely obese adolescents or factors that determine its development. We investigated the prevalence of NAFLD in a multicenter cohort of adolescents undergoing bariatric surgery and the factors associated with it. ...

journal_title：Gastroenterology

authors： Xanthakos SA,Jenkins TM,Kleiner DE,Boyce TW,Mourya R,Karns R,Brandt ML,Harmon CM,Helmrath MA,Michalsky MP,Courcoulas AP,Zeller MH,Inge TH,Teen-LABS Consortium.

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND & AIMS:Drug repositioning offers a shorter approval process than new drug development. We therefore searched large public datasets of drug-induced gene expression signatures to identify agents that might be effective against hepatocellular carcinoma (HCC). METHODS:We searched public databases of messenger R...

journal_title：Gastroenterology

authors： Chen B,Wei W,Ma L,Yang B,Gill RM,Chua MS,Butte AJ,So S

更新日期：2017-06-01 00:00:00

abstract：:This literature review and the recommendations therein were prepared for the American Gastroenterological Association Clinical Practice and Practice Economics committee. The paper was approved by the committee on May 16, 1999, and by the AGA governing board on July 18, 1999. ...

journal_title：Gastroenterology

authors： Zuckerman GR,Prakash C,Askin MP,Lewis BS

更新日期：2000-01-01 00:00:00

abstract：:Cholinergic innervation in the aganglionic bowel of the piebald lethal mouse model of Hirschsprung's disease was investigated by analysis of muscarinic acetylcholine receptors before and after administration of hexamethonium. After hexamethonium administration in the normal rectum, the maximum specific binding (Bmax) ...

journal_title：Gastroenterology

authors： Ueki S,Okamoto E,Kuwata K,Toyosaka A,Nagai K

更新日期：1985-06-01 00:00:00

abstract：:In dispersed acini prepared from guinea pig pancreas, ethanol inhibited the increase in amylase secretion caused by cholecystokinin, carbachol, secretin, or vasoactive intestinal peptide. Ethanol did not alter binding of [125I] vasoactive intestinal peptide to pancreatic acinar cells or the inhibition of binding cause...

journal_title：Gastroenterology

authors： Uhlemann ER,Robberecht P,Gardner JD

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND & AIMS:Hereditary diffuse gastric cancer (HDGC) families carry CDH1 heterozygous germline mutations; their tumors acquire complete CDH1 inactivation through "2nd-hit" mechanisms. Most frequently, this occurs via promoter hypermethylation (epigenetic modification), and less frequently via CDH1 mutations and l...

journal_title：Gastroenterology

authors： Oliveira C,Sousa S,Pinheiro H,Karam R,Bordeira-Carriço R,Senz J,Kaurah P,Carvalho J,Pereira R,Gusmão L,Wen X,Cipriano MA,Yokota J,Carneiro F,Huntsman D,Seruca R

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND & AIMS:Endosonography-guided fine-needle aspiration biopsy (EUS-FNA) permits cytological confirmation of EUS findings. A multicenter prospective evaluation of EUS-FNA for primary diagnosis, staging, and/or follow-up purposes was undertaken. METHODS:EUS-FNA was performed in 457 patients with 554 lesions. Cli...

journal_title：Gastroenterology

authors： Wiersema MJ,Vilmann P,Giovannini M,Chang KJ,Wiersema LM

更新日期：1997-04-01 00:00:00

abstract：:A 20-yr-old man developed recurrent respiratory symptoms and left lower lobe pneumonia 14 yr after long-segment colonic interposition for corrosive esophageal injury. A fistula, from a redundant supradiaphragmatic pouch of colon to a subsegmental bronchus of the lower lobe of the left lung, was discovered and treated ...

journal_title：Gastroenterology

authors： Perlmutter DH,Tapper D,Teele RL,Winter HS

更新日期：1984-06-01 00:00:00

abstract：UNLABELLED:Cerebral evoked potentials provide a technique for evaluation of central nervous processing of information derived from a variety of sensory modalities. Evoked potentials associated with balloon distention of the smooth muscle esophagus were studied in 14 adult volunteers. Stimulation was applied via repeate...

journal_title：Gastroenterology

authors： Castell DO,Wood JD,Frieling T,Wright FS,Vieth RF

更新日期：1990-03-01 00:00:00

abstract：:Congenital esophageal stenosis (CES) is a rare disorder with narrowed esophageal lumen that presents as dysphagia from childhood and that is often associated with tracheobronchial remnants or webs. The pathogenesis of CES is unknown. The aim of this study was to examine the histological and immunohistochemical feature...

journal_title：Gastroenterology

authors： Singaram C,Sweet MA,Gaumnitz EA,Cameron AJ,Camilleri M

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND & AIMS:Trinitrobenzene sulfonic acid (TNBS)-induced colitis is a T-helper 1 (Th1) T cell-mediated inflammation that is rapidly reversed by administration of anti-interleukin (IL) 12. This study sought to define the mechanism of this curative effect. METHODS:Cells and tissue from mice with TNBS colitis recei...

journal_title：Gastroenterology

authors： Fuss IJ,Marth T,Neurath MF,Pearlstein GR,Jain A,Strober W

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND & AIMS:Colonic crypt elongation occurs during both chronic colitis and in the recovery phase of acute colitis. The impact of these alterations on epithelial cell functions is not fully defined. METHODS:DNA microarray analysis of freshly isolated colonic epithelial cells (CECs) from acute and chronic colitis...

journal_title：Gastroenterology

authors： Mizoguchi E,Xavier RJ,Reinecker HC,Uchino H,Bhan AK,Podolsky DK,Mizoguchi A

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND & AIMS:Colorectal cancers (CRC) associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome display high-level microsatellite instability (MSI-H) as a consequence of mismatch repair deficiency. HNPCC-associated CRC frequently show features of a pronounced immune response, most likely resul...

journal_title：Gastroenterology

authors： Schwitalle Y,Kloor M,Eiermann S,Linnebacher M,Kienle P,Knaebel HP,Tariverdian M,Benner A,von Knebel Doeberitz M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND & AIMS:Liver X receptors (LXRs) are transcriptional regulators of cholesterol metabolism, controlling cholesterol flow into cells, catabolism, and efflux. Cholesterol controls cell proliferation; disruptions in cholesterol metabolism have been associated with the development of colon cancer. We investigated ...

journal_title：Gastroenterology

authors： Lo Sasso G,Bovenga F,Murzilli S,Salvatore L,Di Tullio G,Martelli N,D'Orazio A,Rainaldi S,Vacca M,Mangia A,Palasciano G,Moschetta A

更新日期：2013-06-01 00:00:00

abstract：:In ilea of spontaneously infested guinea pigs, we examined the interface between the plasma membranes of cryptosporidia and absorptive cells using thin section and freeze fracture techniques. Initially, cryptosporidia invaginate microvilli, and the resulting redundant folds of membrane envelop the protozoan, thereby i...

journal_title：Gastroenterology

authors： Marcial MA,Madara JL

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND & AIMS:People infected with human immunodeficiency virus (HIV) have an increased risk of some malignancies, but little is known about the effects of infection on risk of cancers of the upper gastrointestinal tract. We evaluated the risks of different histologic and anatomic subtypes of carcinomas and non-Hod...

journal_title：Gastroenterology

authors： Persson EC,Shiels MS,Dawsey SM,Bhatia K,Anderson LA,Engels EA

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND & AIMS:Based on experimental and epidemiologic studies, we investigated whether coffee and caffeine consumption reduced the risk of elevated alanine aminotransferase (ALT) activity in persons at high risk for liver injury in a national, population-based study. METHODS:Participants were 5944 adults in the Th...

journal_title：Gastroenterology

authors： Ruhl CE,Everhart JE

更新日期：2005-01-01 00:00:00

abstract：:Evidence showing that interstitial cells of Cajal have important regulatory functions in the gut musculature is accumulating. In the current study, the ultrastructure of the deep muscular plexus and associated interstial cells of Cajal in human small intestine were studied to provide a reference for identification and...

journal_title：Gastroenterology

authors： Rumessen JJ,Mikkelsen HB,Thuneberg L

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Endogenous nitric oxide has been implicated in the control of mesenteric circulation, but its role in the control of pancreatic blood flow and exocrine pancreatic secretion has not been studied. METHODS:Secretory studies were performed on conscious dogs with chronic pancreatic fistulas, and changes in pancr...

journal_title：Gastroenterology

authors： Konturek SJ,Bilski J,Konturek PK,Cieszkowski M,Pawlik W

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND & AIMS:Proinflammatory cytokines alter function in enteric nerves, but little is known about underlying mechanisms. This study was designed to investigate the roles of prostanoids and of macrophage-like cells in cytokine-induced suppression of [3H]norepinephrine release from rat myenteric plexus. METHODS:Th...

journal_title：Gastroenterology

authors： Rühl A,Berezin I,Collins SM

更新日期：1995-12-01 00:00:00