Abstract:
BACKGROUND:Endoscopic third ventriculostomy (ETV) has gained wide popularity as a first-line treatment for obstructive hydrocephalus (OHC). We have been performing ETV since 1998. We report our experience with this technique in the management of OHC. METHODS:Between 1998 and 2007, we performed 49 ETV procedures in 46 patients suffering from OHC. Medical records were retrospectively reviewed. Success was defined as shunt-free survival. RESULTS:There were 29 males and 17 females with a mean age of 23 years (6 months-65 years). Aqueductal stenosis and tectal tumor were the most common etiologies (63%). Seven patients (15.6%) had early ETV failure. Of 38 patients with initial success and available follow-up, shunt independence was achieved in 29 patients (76.3%) after a mean follow-up of 37 months. Kaplan-Meier analysis yielded a 70% 5-year shunt-free survival rate. On multivariate analysis, no variables could predict early or late ETV failure. Transient complications occurred in 6 patients (13%), but there were no ETV-related deaths or permanent morbidity. CONCLUSION:ETV is a safe and effective treatment for OHC, resulting in a high rate of long-term shunt independence with a low risk of complications. ETV should be considered the treatment of choice for patients with OHC and its development as a substitute to shunt placement should be encouraged in neurosurgically developing countries.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Rahme R,Rahme RJ,Hourani R,Moussa R,Nohra G,Okais N,Samaha E,Rizk Tdoi
10.1159/000257525subject
Has Abstractpub_date
2009-01-01 00:00:00pages
361-7issue
5eissn
1016-2291issn
1423-0305pii
000257525journal_volume
45pub_type
杂志文章abstract:OBJECT:The evolution and severity of hydrocephalus in animal models varies in the species and mode of induction. This makes comparisons of the physiological system under investigation difficult between models. We noted that injection of kaolin into neonatal rats results in a dichotomous outcome into either an acute or ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000055975
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Achondroplasia is the commonest form of human dwarfism. The authors report atlanto-axial instability, in consequence to os odontoideum in this subgroup of patients. METHODS:Two achondroplastic dwarfs harboring atlanto-axial dislocation are described along with radiological findings. RESULTS:Both children u...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000335433
更新日期:2011-01-01 00:00:00
abstract::Osteoblastomas and aneurysmal bone cysts are uncommon benign tumors of the spine. Their presentation can vary between diffuse pain, restriction of neck movements, torticollis, radiculopathy, and myelopathy. Complete excision is the best treatment to achieve a cure, but recurrence is not uncommon. A combination of the ...
journal_title:Pediatric neurosurgery
pub_type:
doi:10.1159/000495065
更新日期:2019-01-01 00:00:00
abstract::Molecular genetic analysis of several common cancers has yielded information concerning their etiology and prognosis. Restriction fragment length polymorphism (RFLP) studies showing consistent loss of specific DNA sequences in tumor tissue have identified genes, known as tumor suppressors, associated with the etiology...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000120605
更新日期:1991-01-01 00:00:00
abstract::Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are dire neurological disorders, characterized by severe damage to the myelin sheath of neurons, which typically result from rapid correction or overcorrection of systemic hyponatremia. For many years, both conditions have been considered universal...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000320146
更新日期:2010-01-01 00:00:00
abstract::The purpose of this study was to examine the current patterns of head trauma associated with child abuse. We reviewed the records of all patients admitted to our medical center between 1995 and 1997 with a primary diagnosis of head trauma, and analyzed the clinical presentation, mechanism of injury, socioeconomic stat...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028880
更新日期:1999-12-01 00:00:00
abstract::During the last decade, rapid progress has been made in understanding the molecular pathways underlying the proliferation of both normal and neoplastic cells. The processes by which messages to initiate protein synthesis, cell cycle progression, and even cell death are transmitted from the cell surface or the cytoplas...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028729
更新日期:1998-11-01 00:00:00
abstract::Several groups have begun to explore the feasibility and utility of intrauterine closure of myelomeningocele. A subset of these fetuses have defects which fall into the category of myeloschisis, and therefore have inadequate skin to enable primary closure. After considerable discussion, it was decided to utilize biped...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028898
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:Pediatric low-grade gliomas comprise a diverse range of central nervous system tumors, sharing the usual course of a slow progression in growth. In individual cases however, the natural history can be variable, and rarely spontaneous regression has been described. This paper describes factors associated with ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000134925
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To induce experimental split cord malformations (SCMs) produced through the surgical induction of a dorsal midline fistula. METHODS:In addition, the theory of embryogenesis of SCMs was verified by examining the developmental process of this experimentally induced anomaly. In Cynopus pyrrhogaster (amphibian) ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000058425
更新日期:2002-05-01 00:00:00
abstract::Intracranial schwannomas not arising from a cranial nerve are very rare. Schwannomas of the dura are even rarer; in the literature, we found only two cases: a schwannoma of the falx and one of the torcula. We report a third case of a 9-year-old girl with a schwannoma of the tentorium cerebelli. The different theories ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000048371
更新日期:2002-03-01 00:00:00
abstract::Though detected with increasing frequency, intracranial carotid artery dissection remains less common in infancy. We report on 3 otherwise healthy children aged 8, 12 and 15 years who presented with focal headache and stroke secondary to intracranial carotid occlusive disease consistent with arterial dissection. In 2 ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120844
更新日期:1994-01-01 00:00:00
abstract::In contrast to neoplasia, lesions of focal cerebral dysplasia are thought to be completed developmental processes of abnormal neuronal migration. We present three children with seizures resulting from brain lesions which pathologically demonstrate regions of both clearcut focal cortical dysplasia and also hypercellula...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028662
更新日期:1998-05-01 00:00:00
abstract:AIM:Meningiomas are very rare in children comprising only 0.44.1% of pediatric age tumors and only 1.5-1.8% of all intracranial neoplasms. We analyzed the clinical, pathological and management profile of these rare tumors and elucidated their differences from meningiomas in adults. METHODS:From 1990 to 2005, 33 patien...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000110661
更新日期:2008-01-01 00:00:00
abstract::We present a case report of a 21-month-old female patient to highlight magnetic resonance (MR) imaging findings associated with papilledema in a pediatric patient with an intracranial tumor. The MR findings included optic disc elevation, dilated perioptic subarachnoid spaces, optic nerve tortuosity and restricted diff...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000270156
更新日期:2009-01-01 00:00:00
abstract::Fetus in fetu (FIF) is an extremely rare congenital anomaly in the pediatric age group. It is defined by the presence of an axial skeleton and well-formed internal organs in a fetiform mass. Only about 15 cases of intracranial FIF have been reported in the literature worldwide. We report a case of temporo-occipitocerv...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000441035
更新日期:2016-01-01 00:00:00
abstract::Wakeboarding is a relatively new and exciting sporting activity which is similar to water-skiing. While there have been several reports of water-skiing-related injuries, there has been nothing reported in the literature so far concerning injuries in wakeboarding. We present the case of a 14-year-old male who sustained...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028957
更新日期:2000-06-01 00:00:00
abstract::We report a 16-year-old healthy boy who presented with sudden loss of vision in both eyes, accompanied by a mild headache. Magnetic resonance imaging showed a chiasmal apoplexy. An urgent craniotomy revealed a cavernous malformation of the chiasm, which was evacuated. There was a subsequent dramatic improvement in bil...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000149911
更新日期:2008-01-01 00:00:00
abstract::Angiofibromas are rare tumors of the head and neck that mostly occur in the sphenopalatine region. We present a case of angiofibroma in a young male patient with an unusual and extremely rare localization, which to our knowledge has not been described before. It was situated in the tentorium and spread to the supraten...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000448051
更新日期:2016-01-01 00:00:00
abstract::Atlantoaxial rotatory subluxation (AARS) is an uncommon disease with a greater prevalence in children than adults. So far there has only been one report of AARS after surgery related to ventriculoperitoneal (VP) shunting. We present a new case of AARS closed reduction treatment after VP shunt removal in an 8-year-old ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000433601
更新日期:2015-01-01 00:00:00
abstract::Arachnoid cysts are collections of cerebrospinal fluid covered by arachnoidal cells and collagen. They may have a congenital or acquired origin. We present the case of a 7-year-old boy with a cerebellopontine angle arachnoid cyst harbouring a portion of neuroglia. Microscopically, the cyst wall consisted of a delicate...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000086566
更新日期:2005-07-01 00:00:00
abstract:AIM:To study the outcome and recurrence in supratentorial anaplastic ependymoma. METHODS:Sixteen cases of supratentorial anaplastic ependymoma were reviewed. The average age of presentation was 8.2 years ranging from 1 to 16 years of age. The mean duration between the onset of first symptoms to time of presentation wa...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000106384
更新日期:2007-01-01 00:00:00
abstract::Attempts at radical excision of craniopharyngioma has been made increasingly possible by the advent of neuroradiological imaging and the use of microscopic technique. Between 1977 and 1993, 62 patients of The National Hospital for Neurology and Neurosurgery, London, have undergone surgical excision of craniopharyngiom...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120864
更新日期:1994-01-01 00:00:00
abstract::To compare the functional development of the fourth ventricular outlet in the myeloschisis-Chiari malformation complex with that of a normal brain, the chronological development of the outlet in C57BL/6J non-neural-tube defect mouse embryos was examined as the first step. Then we compared the results with those of hom...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121248
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Animal experiments have suggested that the intrauterine environment causes secondary injury to the congenitally dysplastic spinal cord. This in turn suggests that early closure of the myelomeningocele sac might prevent secondary injury and therefore improve neurologic outcome. This study was designed to exam...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000048358
更新日期:2002-02-01 00:00:00
abstract::Congenital dermal sinus tract of the spine is an unusual developmental defect which represents a failure of the surface ectoderm and dermal elements to separate from the neuroectoderm. A 15-month-old female presented with high fever, severe right hemiparesis, difficulty breathing and cranial nerve deficits. Magnetic r...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000439539
更新日期:2015-01-01 00:00:00
abstract::Early diagnosis of skull fibrous dysplasia in children is relatively easy, based on a history of painless progressive bony bulging. The therapeutic approach is still controversial, due to the benignity of the lesion. However, the clinical course may be unpredictable, with sudden appearance of symptoms, some of which c...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120649
更新日期:1992-01-01 00:00:00
abstract::Hepatic pseudocyst formation is a rare intra-abdominal complication of ventriculoperitoneal shunts. The presence of an intracranial tumor and a history of central nervous system infection are major risk factors for the development of this complication. Hepatic pseudocysts secondary to ventriculoperitoneal shunts can b...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000108795
更新日期:2007-01-01 00:00:00
abstract::Premature separation of the neuroectoderm from the ipsilateral surface ectoderm allowing mesenchymal tissue to invade into the central canal, or "premature dysjunction" theory, was proposed for the pathogenesis of dorsal type lumbosacral lipoma. To test this theory, the unilateral neural fold was incised using Hamburg...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000056007
更新日期:2001-03-01 00:00:00
abstract::Epidermoid cysts (ECs) are rare developmental lesions occurring anywhere along the central nervous system. Usually affecting adult patients, the occurrence of supratentorial dorsal cistern ECs has been reported in only 1 certain case of pediatric age. An additional pediatric case is presented. An 11-year-old boy had a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028722
更新日期:1998-10-01 00:00:00