Abstract:
OBJECTIVE:Pediatric low-grade gliomas comprise a diverse range of central nervous system tumors, sharing the usual course of a slow progression in growth. In individual cases however, the natural history can be variable, and rarely spontaneous regression has been described. This paper describes factors associated with spontaneous regression. METHODS:A literature review was performed to identify factors associated with spontaneous regression. A unique case is described to contribute to the findings. RESULTS:Low-grade gliomas occurring in association with neurofibromatosis are more likely to spontaneously regress. Only 14 cases of spontaneous regression of low-grade gliomas in patients without neurofibromatosis have been described, and of these, the vast majority regress in association with optic chiasm gliomas. We describe the first documented case of spontaneous regression of a temporal lobe pilocytic astrocytoma in a patient without neurofibromatosis. CONCLUSION:Spontaneous regression of low-grade gliomas can occur for tumors in a diversity of anatomical locations, at varying ages and in both sexes. This may have implications for management. As such, spontaneous tumor regression is an important outcome to be considered for pediatric low-grade gliomas and pilocytic astrocytomas.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Rozen WM,Joseph S,Lo PAdoi
10.1159/000134925subject
Has Abstractpub_date
2008-01-01 00:00:00pages
324-8issue
4eissn
1016-2291issn
1423-0305pii
000134925journal_volume
44pub_type
杂志文章,评审abstract:INTRODUCTION:Nondysraphic intramedullary lipomas of the spinal cord are rare lesions. They are most commonly seen in the second or third decade of life. Their occurrence in the pediatric age group is even rarer. CASE REPORT:The authors describe a 14-month-old child who presented with delayed motor milestones involving...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000334258
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:An international multicenter randomized trial comparing standard pressure differential valves, Orbis Sigma valves and PS Medical Delta valves, for children with newly diagnosed hydrocephalus failed to show a difference in the time to first shunt failure (power 80%). In order to avoid observer bias, the pri...
journal_title:Pediatric neurosurgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000028764
更新日期:1999-02-01 00:00:00
abstract::This is a report of a prenatal sonographic diagnosis of a lateral ventricle choroid plexus papilloma in an in vitro fertilization (IVF)-induced pregnancy of a 40-year-old woman. The baby was delivered at 35 weeks of gestation and surgery was performed 5 days later with a good outcome. Several cases of malignancies ass...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000066210
更新日期:2002-11-01 00:00:00
abstract::Schimmelpenning syndrome is a rare, well-defined constellation of clinical phenotypes associated with the presence of nevus sebaceous and multisystem abnormalities most commonly manifested as cerebral, ocular, and skeletal defects [
journal_title:Pediatric neurosurgery
pub_type:
doi:10.1159/000497149
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:An 11-month-old boy with autosomal recessive infantile osteopetrosis presented, 7 months after bone marrow transplantation, with normal ventricular size and life-threatening intracranial hypertension due to pansynostosis. METHODS:The cranial vault was expanded by using jackscrew distracters to upwardly adva...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000098381
更新日期:2007-01-01 00:00:00
abstract::Surgical reconstruction of cranial deformities and synostosis is occasionally accompanied by incomplete bone growth to cover all areas of cranial vault that have been exposed in the correction. The restrictive nature of some forms of synostosis require more bone in the repair than is available using the child's natura...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120959
更新日期:1995-01-01 00:00:00
abstract::The computed tomographic (CT) scanning characteristics of a case of intra-fourth-ventricle mature teratoma in a 15-month-old child are described and correlated with intraoperative findings. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028795
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVE:Cephalocele is a central nervous system (CNS) birth defect. Various CNS and extra-CNS anomalies, as well as prognostic factors have been reported with cephalocele. The aim of this study was to discuss prognostic factors and current possible theories explaining associated anomalies seen in a series of 55 patie...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000277622
更新日期:2009-01-01 00:00:00
abstract::Thirty-seven patients with Dandy-Walker malformation were treated between 1959 and 1989. Eighty percent of patients became symptomatic by 3 years of age, with 70% presenting within the 1st year of life. Hydrocephalus was present in 91% of patients at the time of diagnosis. Clinical presentation was most often heralded...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120660
更新日期:1992-01-01 00:00:00
abstract::Cavernous malformations (CMs) of the central nervous system are benign, angiographically occult vascular lesions and are diagnosed by magnetic resonance imaging techniques. Giant CMs do not differ from smaller-sized CMs in their clinical, surgical or histopathological presentation but may be radiologically different. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000447407
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Midline suboccipital craniotomy has been proposed as an alternative to conventional craniectomy for removal of posterior fossa tumors. METHOD:We describe a modified technique for midline suboccipital osteoplastic craniotomy based on the atlantooccipital membrane for a 17-year-old boy with superior vermian a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000354220
更新日期:2012-01-01 00:00:00
abstract::Associated cranial abnormalities with spinal dysraphism are not uncommon. We came across an unusual case of a 1-year-old male child with spinal dysraphism having lumbar meningomyelocele, who also had split cord malformation (hemicord with intervening bony spur) with lipoma of one of the hemicord and filum terminale. T...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000091862
更新日期:2006-01-01 00:00:00
abstract::Inflicted traumatic brain injury (TBI) is a frequent consequence of physical child abuse in infants and children. Twenty-eight children who were 2-42 months of age when hospitalized for moderate to severe TBI were enrolled in a prospective, longitudinal study of neurobehavioral outcome following acquired brain injury....
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028872
更新日期:1999-11-01 00:00:00
abstract::Although the transsphenoidal approach offers a narrow operative field and poor visual control through a small sellar opening, this approach has the advantage of being associated with minimal surgical trauma, especially in children. We share our experience of good surgical outcome achieved by the transsphenoidal approa...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000071321
更新日期:2003-07-01 00:00:00
abstract::Spondylolysis and spondylolisthesis can be associated with significant low back pain, especially in physically active adolescents. Non-operative management is usually successful in improving symptoms, but surgical intervention is occasionally required for those that fail reduction of activity and bracing. In a subpopu...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000072471
更新日期:2003-10-01 00:00:00
abstract::Spinal dysraphism is characterized by a lack of fusion of the vertebral arches that occurs in the absence of spinous processes with variable amounts of lamina. Here, we retrospectively present the importance of cutaneous lesions and their correlation with clinical presentation, radiological examination and urodynamic ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000149901
更新日期:2008-01-01 00:00:00
abstract::Tumors located in the region of the foramen of Monro often present with signs and symptoms of obstructive hydrocephalus. Various types of lesions occur in this location. We describe a case of a dysembryoplastic neuroepithelial tumor of the septum pellucidum presenting with obstructive hydrocephalus and its successful ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000090464
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Spinal cord injury (SCI) is a leading cause of morbidity and mortality among youth and adults. Secondary injury mechanisms within the spinal cord (SC) are well known to cause deterioration after an acute impact. Free radical scavengers are among the most studied agents in animal models of SCI. Edaravone is a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000335400
更新日期:2011-01-01 00:00:00
abstract::Atlantoaxial rotatory subluxation (AARS) is an uncommon disease with a greater prevalence in children than adults. So far there has only been one report of AARS after surgery related to ventriculoperitoneal (VP) shunting. We present a new case of AARS closed reduction treatment after VP shunt removal in an 8-year-old ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000433601
更新日期:2015-01-01 00:00:00
abstract::Blunt carotid injury (BCI) is an uncommon yet potentially devastating entity which has received little attention in the pediatric literature. In an attempt to better characterize pediatric BCI, a review of the National Pediatric Trauma Registry was performed. Records were obtained from all children diagnosed with inte...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028804
更新日期:1999-05-01 00:00:00
abstract::An intradural, intramedullary lipoma originating within the upper cervical cord with significant extension into the posterior fossa is reported in an infant. Two additional lipomas were found in the lumbar region. This constellation of findings represents the first description of multiple intradural, intramedullary sp...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121008
更新日期:1996-01-01 00:00:00
abstract::Intracranial schwannomas not arising from a cranial nerve are very rare. Schwannomas of the dura are even rarer; in the literature, we found only two cases: a schwannoma of the falx and one of the torcula. We report a third case of a 9-year-old girl with a schwannoma of the tentorium cerebelli. The different theories ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000048371
更新日期:2002-03-01 00:00:00
abstract::Stereotactic radiosurgery has had an increasing role in the treatment of selected intracranial lesions in pediatric patients. In our first 44 months experience, 60 of the patients (9%) treated were less than or equal to 18 years of age. Current indications for radiosurgery include primary treatment of high-risk arteri...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120530
更新日期:1990-01-01 00:00:00
abstract::A rare case involving multiple intracranial aneurysms with intraventricular hemorrhage (IVH) in a child, accompanied by unilateral fibromuscular dysplasia (FMD) of the renal artery, is reported. A 12-year-old girl presented with secondary hypertension and fourth-ventricle IVH. Cerebral angiography showed multiple aneu...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000180304
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Tumours of the choroid plexus are rare tumours of neuro-ectodermal origin, accounting for less than 1% of all intracranial tumours. Most cases present in children less than 2 years of age. While choroid plexus carcinomas (CPC) are reported to have an extremely poor prognosis, choroid plexus papillomas (CPP) a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028933
更新日期:2000-04-01 00:00:00
abstract::Eight myelodysplastic children developed isolated lateral ventriculomegaly following shunt insertion for progressive hydrocephalus after closure of a myelomeningocele. In all patients a low-pressure distal slit valve (Uni-shunt) system preceded development of an isolated contralateral ventricle. Six of 8 children requ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120547
更新日期:1990-01-01 00:00:00
abstract::The authors report a 7-year-old girl who presented with progressive quadriparesis which had started a month before admission. Magnetic resonance imaging of the spine revealed an intramedullary cystic lesion extending from C(2) to C(4). After performing a C(2-5) laminectomy, the cyst was drained and anatomically fenest...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000097527
更新日期:2007-01-01 00:00:00
abstract::Staphylococcus lugdunensis, a coagulase-negative staphylococcus first described in 1988, has gained recognition as an organism with considerable pathogenic capability in adults. In contrast to the indolent presentation characteristic of other coagulase-negative staphylococci, S. lugdunensis infections resemble the agg...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000050405
更新日期:2001-09-01 00:00:00
abstract::Skull defects in children may be congenital or acquired after trauma, infection or tumor. For defects that do not close spontaneously a variety of repair (cranioplasty) materials are available including bone, metals and acrylic. Where possible calvarial autogenous bone is preferred, particularly in younger infants, bu...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120540
更新日期:1990-01-01 00:00:00
abstract::An infant sustained a significant depressed skull fracture from a fall. Before the planned surgical repair of the fracture could be carried out, the child sustained a second fall that led to the complete resolution of the depressed fracture. Mechanisms to explain this unusual phenomenon are discussed. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000334279
更新日期:2011-01-01 00:00:00