Abstract:
:Spinal dysraphism is characterized by a lack of fusion of the vertebral arches that occurs in the absence of spinous processes with variable amounts of lamina. Here, we retrospectively present the importance of cutaneous lesions and their correlation with clinical presentation, radiological examination and urodynamic assessment. We retrospectively reviewed 612 (6.12%) cases with skin lesions from 10,000 consecutive live-born children seen at two institutions between January 1998 and March 2005. We divided all children into a control group and three groups based on clinical assessment, radiological examination and urodynamic evaluation results. Neurological deficits were identified in 113 (18.46%) children, while spinal dysraphism disorders, tethered cord syndrome and associated orthopedic malformations were found in 171 (27.94%), 119 (19.45%) and 28 (4.57%) patients, respectively. The incidence of tethered cord with lumbosacral dimple lesions over the sacrum (32/119, 26.65% of patients) was 3.5-fold higher than that of lesions found over the coccyx (9/119, 7.5% of patients). Uroneurological symptoms were found in 207/612 (33.82%) children. Urodynamic assessment revealed decreased bladder capacity in 10% of patients, detrusor hyperflexia during filling in 47% and a low-compliance detrusor in 71%. Discordance between ultra- sonography and MRI was found in 16.58% of patients. Spinal cord untethering was performed for 109 patients. Nearly all children with resolution were at the end of their follow-up period (24 months). Retethering occurred in 21 (19.26%) patients, and a second untethering surgery was performed in 12 patients. When spina bifida was associated with lumbar skin lesions, there may have been an increased incidence of tethered cord and other spinal cord disorders. MRI scans are more reliable and give an exact diagnosis of tethered cord. Neurological and uroneurological instability are ultimately a clinical diagnosis, and there is controversy about their indications for surgery. However, the correlation between urodynamic assessment and cutaneous lesions with a tethered cord found by MRI examination allow for an early diagnosis and the possibility of prompt treatment.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Sasani M,Asghari B,Asghari Y,Afsharian R,Ozer AFdoi
10.1159/000149901subject
Has Abstractpub_date
2008-01-01 00:00:00pages
360-70issue
5eissn
1016-2291issn
1423-0305pii
000149901journal_volume
44pub_type
杂志文章abstract:BACKGROUND/AIMS:Central nervous system germ cell tumors (CNS-GCTs) are relatively rare. While their incidence was thought to be higher in East Asia than the USA, recent evidence suggests the difference between Japan and the USA is not statistically significant. The aim of this study was to determine the rate of pediatr...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1159/000358806
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Craniosynostosis patients treated with one-stage cranioplasty often have bleeding from the dura mater, fluid collection in the extradural space, and poor wound healing due to skin overstretching. To avoid these complications, we began using distraction osteogenesis. To determine the advantages and disadvantages...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000094064
更新日期:2006-01-01 00:00:00
abstract::The use of temporal lobectomy for the treatment of intractable complex partial seizures of temporal lobe origin has a long and successful history. When appropriately applied in children, excellent seizure control and neurodevelopmental progress are expected. This article reviews patient selection, evaluating the surgi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000056036
更新日期:2001-05-01 00:00:00
abstract::We discuss the surgical approach used for and outcome in 11 infants (< or =3 years) who were treated at our institution for ependymomas arising in the cerebellar-pontine (C-P) angle. The median age of the group was 19 months (range: 6-26 months). Of these 11 patients, the initial surgery for 8 was performed at our cen...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121232
更新日期:1997-08-01 00:00:00
abstract::Congenital dermal sinus tract of the spine is an unusual developmental defect which represents a failure of the surface ectoderm and dermal elements to separate from the neuroectoderm. A 15-month-old female presented with high fever, severe right hemiparesis, difficulty breathing and cranial nerve deficits. Magnetic r...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000439539
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The Delta valve is a pressure differential valve with a siphon control device. The valve mechanism is normally closed, but is designed to open in response to positive ventricular pressure, thereby avoiding overdrainage of cerebrospinal fluid (CSF). As a result, the incidence of subdural fluid collections as w...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028988
更新日期:2000-08-01 00:00:00
abstract::This is a report of a prenatal sonographic diagnosis of a lateral ventricle choroid plexus papilloma in an in vitro fertilization (IVF)-induced pregnancy of a 40-year-old woman. The baby was delivered at 35 weeks of gestation and surgery was performed 5 days later with a good outcome. Several cases of malignancies ass...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000066210
更新日期:2002-11-01 00:00:00
abstract::The authors studied 58 patients, under 12 years of age, admitted to the Emergency Room of the Sao Paulo University Hospital between September 1987 and November 1991 with the diagnosis of traumatic extradural hematoma. Emphasis was given to the etiology of injury, the time interval from head injury to emergency room ev...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120814
更新日期:1994-01-01 00:00:00
abstract::Hemifacial spasm (HFS), generally a disease of the elderly, is caused by vascular compression of the seventh nerve. Vascular compression is thought to result from atherosclerotic changes within the vessels of the posterior fossa, and therefore rarely presents in childhood. Here we describe our experience with 12 patie...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121260
更新日期:1997-11-01 00:00:00
abstract::The placement of a ventriculoperitoneal (VP) shunt is the most common form of treatment for hydrocephalus.The distal end of the VP shunt is commonly placed in the peritoneal cavity. Various complications of the distal end of the shunt have been described in the literature.We report an unusual case of perforation of th...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000204904
更新日期:2009-01-01 00:00:00
abstract::Cyanotic breath-holding spell is a benign and self-limiting disease of young children but occasionally associated with sudden, unexpected death. The authors report a rare case in a 2-year-old girl with a severe form that started after radical resection of a cervicomedullary ganglioglioma. She was admitted to our hospi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000085163
更新日期:2005-03-01 00:00:00
abstract::Primary germ cell tumors confined to the optic nerves and chiasm without suprasellar extension are uncommon. These tumors appear similar to chiasmatic gliomas on both computed tomography and magnetic resonance imaging, potentially resulting in treatment errors if the diagnosis is based on radiologic criteria alone. Un...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120927
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:Cephalocele is a central nervous system (CNS) birth defect. Various CNS and extra-CNS anomalies, as well as prognostic factors have been reported with cephalocele. The aim of this study was to discuss prognostic factors and current possible theories explaining associated anomalies seen in a series of 55 patie...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000277622
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:The majority of the present distraction osteogenesis techniques involve local site expansion that only produces localized decompression and affords limited decompression and cosmetic results. We designed a new surgical procedure, total calvarial transsutural distraction osteogenesis (TSuDO). METHODS:We pe...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000381860
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:An 11-month-old boy with autosomal recessive infantile osteopetrosis presented, 7 months after bone marrow transplantation, with normal ventricular size and life-threatening intracranial hypertension due to pansynostosis. METHODS:The cranial vault was expanded by using jackscrew distracters to upwardly adva...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000098381
更新日期:2007-01-01 00:00:00
abstract::We report a 16-year-old healthy boy who presented with sudden loss of vision in both eyes, accompanied by a mild headache. Magnetic resonance imaging showed a chiasmal apoplexy. An urgent craniotomy revealed a cavernous malformation of the chiasm, which was evacuated. There was a subsequent dramatic improvement in bil...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000149911
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND/AIMS:The object of this report is to review the management of patients having the composite type of aplasia cutis congenita in the context of the relevant literature on this condition. METHODS:Clinical records, neuroimaging and photographic documentation of identified cases of composite type aplasia cutis c...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000442989
更新日期:2016-01-01 00:00:00
abstract:UNLABELLED:Since 1990, 110 retrograde ventriculo-sinus (RVS) shunts were implanted; 98 patients (89.1%) benefited - 1 of them (0.9%) after shunt revision. The manifestations of high intra cranial pressure (ICP) disappeared, there were no problems related to improper cerebrospinal fluid (CSF) drainage, and the transcran...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000088733
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:Modern neuroimaging and intensive care permit precise delineation and specific treatment of head injury. Children sustaining cranial trauma associated with epidural hematoma (EDH) represent a heterogeneous group with a variety of clinical outcomes. Treatment consists of simple observation or surgical evacuati...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121144
更新日期:1996-12-01 00:00:00
abstract::Early diagnosis of skull fibrous dysplasia in children is relatively easy, based on a history of painless progressive bony bulging. The therapeutic approach is still controversial, due to the benignity of the lesion. However, the clinical course may be unpredictable, with sudden appearance of symptoms, some of which c...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120649
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Composite-type split spinal cord malformation (SCM) is very rare and results from 2 separate foci of ectoendodermal adhesions and endomesenchymal tracts leading to the development of SCM with an intervening normal cord in the same patient. Posterior spurs are even rarer. We report a unique case of composite ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000336752
更新日期:2011-01-01 00:00:00
abstract::Two cases of aneurysmal malformations of the vein of Galen (AVG) with spontaneous thrombosis are reported. Angiogram and MRI before thrombosis demonstrated AVGs with slow arteriovenous shunts and associated stagnation of contrast in the venous sac secondary to severe outflow restriction. Based on these findings, one p...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028828
更新日期:1999-07-01 00:00:00
abstract::Kernohan-Woltman notch phenomenon (KWNP) is an ipsilateral motor weakness due to compression of the contralateral cerebral peduncle. Most of the KWNP cases reported have been due to subdural hematomas, intracranial space-occupying lesions, and spontaneous bleeding of vascular malformations. In this study, we present t...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000474945
更新日期:2017-01-01 00:00:00
abstract::Craniopharyngiomas are the most common pediatric suprasellar tumor. While they are benign by histology, their location in the brain predisposes craniopharyngiomas to be associated with both acute and chronic neurologic, endocrine, visual, neuropsychologic and psychosocial problems. Because of the complexity of problem...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000120872
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:To induce experimental split cord malformations (SCMs) produced through the surgical induction of a dorsal midline fistula. METHODS:In addition, the theory of embryogenesis of SCMs was verified by examining the developmental process of this experimentally induced anomaly. In Cynopus pyrrhogaster (amphibian) ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000058425
更新日期:2002-05-01 00:00:00
abstract::Three patients with colloid cysts were identified among approximately 1,400 patients with brain tumors seen at the Hospital for Sick Children in Toronto between 1952 and 1992. These and 34 previously published cases of colloid cysts in children were reviewed. Colloid cysts are rare causes of headaches and papilloedema...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000120782
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:Our appreciation and understanding of what is now known as the split cord malformation (SCM) have a long history. The oldest known example of SCM is from roughly AD 100. Other isolated examples can be found in the large body of work of the pathologists of the 1800s, where the SCMs were found incidentally d...
journal_title:Pediatric neurosurgery
pub_type: 历史文章,杂志文章
doi:10.1159/000450584
更新日期:2017-01-01 00:00:00
abstract::Radiotherapy has remained the mainstay of treatment for children with intrinsic, diffuse pontine tumors in spite of over 20 years of clinical trials attempting to validate the additional role of chemotherapy. Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas us...
journal_title:Pediatric neurosurgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000121024
更新日期:1996-01-01 00:00:00
abstract::Though detected with increasing frequency, intracranial carotid artery dissection remains less common in infancy. We report on 3 otherwise healthy children aged 8, 12 and 15 years who presented with focal headache and stroke secondary to intracranial carotid occlusive disease consistent with arterial dissection. In 2 ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120844
更新日期:1994-01-01 00:00:00
abstract::A needle for intravenous fluid administration in a newborn was accidentally placed in the sagittal sinus and resulted in dural sinus air embolism. CT findings are described and the risks for venous air embolism are discussed. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120606
更新日期:1991-01-01 00:00:00