CPAP treatment in the coexistence of obstructive sleep apnea syndrome and metabolic syndrome, results of one year follow up.

Abstract:

OBJECTIVE:To investigate the effect of one year continuous positive airway pressure (CPAP) treatment on metabolic syndrome (MS) prevalence and components in patients diagnosed with both obstructive sleep apnea syndrome (OSAS) and metabolic syndrome. METHODS:This was a single center, observational prospective cohort study. 38 patients who were diagnosed with OSAS after polysomnographic analysis in sleep laboratory and diagnosed with MS according to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guideline and underwent CPAP treatment were followed for one year. After the 1 year of follow up period on CPAP treatment, the prevalence of MS was evaluated again. RESULTS:20 (13 male, 7 female) of 38 patients completed the entire study. Mean age was 50+/-7.7.4 patients were under treatment for diabetes mellitus (DM), 9 for hypertension (HT). After one year of follow up on CPAP treatment, the prevalence of MS decreased by 45%. When each components of MS were evaluated, no significant difference was found in fasting blood glucose, triglyceride levels and systolic and diastolic blood pressure after treatment (p>0.05). However, significant difference was observed in waist circumference (p=0.002), HDL cholesterol (p=0.001) and BMI (p=0.01) after treatment. DISCUSSION:If MS accompanies OSAS, which is a cardiovascular risk factor by itself, treatment indications of CPAP should be reevaluated. Thus, if OSA patients meet the criteria of MS even though they do not have obvious DM, HT and hyperlipidemia, initiating CPAP treatment at lower AHI levels may contribute to the prevention and development of cardiovascular disease.

journal_name

Acta Clin Belg

journal_title

Acta clinica Belgica

authors

Oktay B,Akbal E,Firat H,Ardiç S,Kizilgun M

doi

10.1179/acb.2009.051

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

329-34

issue

4

eissn

1784-3286

issn

2295-3337

journal_volume

64

pub_type

杂志文章
  • Systematic review of proposed definitions of nocturnal polyuria and population-based evidence of their diagnostic accuracy.

    abstract::Background Evidence of diagnostic accuracy for proposed definitions of nocturnal polyuria is currently unclear. Purpose Systematic review to determine population-based evidence of the diagnostic accuracy of proposed definitions of nocturnal polyuria based on data from frequency-volume charts. Methods Seventeen pre-spe...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2018.1427821

    authors: Olesen TK,Denys MA,Vande Walle J,Everaert K

    更新日期:2018-08-01 00:00:00

  • Belgian multicentre study on the in vitro activity of cefepime against gram-negative bacilli.

    abstract::The in vitro activity of cefepime has been compared with that of cefotaxime, ceftazidime, aztreonam, and piperacillin against 1826 Enterobacteriaceae including 537 inducible Enterobacteriaceae (Enterobacter spp., Serratia spp., Citrobacter spp,. Morganella morganii) and 572 non-fermenters, including 401 Pseudomonas ae...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Verbist L,Glupczynski Y

    更新日期:1996-01-01 00:00:00

  • Hypertension and the kidney.

    abstract::The kidney could be the cause of essential hypertension which can also cause renal disease. High blood pressure is also very common in chronic kidney disease, and is moreover a well-known risk factor for a faster progression of kidney failure. Hypertension and kidneys are thus closely linked. Hypertension must be aggr...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2007.002

    authors: Krzesinski JM,Cohen EP

    更新日期:2007-01-01 00:00:00

  • Massive pericardial effusion and rhabdomyolysis secondary to untreated severe hypothyroidism: the first report.

    abstract::Hypothyroidism is an endocrine disease with various clinical manifestations. It is a rare cause for rhabdomyolysis and massive pericardial effusion. We describe a case of severe hypothyroidism secondary to autoimmune hashimoto thyroiditis with massive pericardial effusion and rhabdomyolysis. Improvement of mentioned c...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/2295333714Y.0000000049

    authors: Zare-Khormizi MR,Rahmanian M,Pourrajab F,Akbarnia S

    更新日期:2014-10-01 00:00:00

  • Microvesicular steatosis of the liver.

    abstract::The term "microvesicular steatosis of the liver" refers to a variant form of hepatic fat accumulation whose histologic features contrast with the much more common macrovesicular steatosis. Microvesicular steatosis of the liver was originally described in association with conditions who share a number of biochemical an...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1080/17843286.1990.11718105

    authors: Hautekeete ML,Degott C,Benhamou JP

    更新日期:1990-01-01 00:00:00

  • [Study of a group of diabetic patients enrolled in the INAMI convention "Self-monitoring of blood glucose"].

    abstract::We have studied the clinical characteristics of 126 insulin-treated diabetic patients, mainly type I subjects, who regularly performed during 18 months home glucose monitoring. The numbers of strips used each month was of 60 +/- 33 (mean +/- lSD). During the study period, HbA1C levels decreased from 8.6 +/- 2.1 to 7.0...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.1993.11718324

    authors: Buysschaert M,Lambert L,Donckier J,Jamart J

    更新日期:1993-01-01 00:00:00

  • A randomized placebo controlled trial on the effects of simvastatin, a HMG-CoA reductase inhibitor, on blood lipids and fibrinolytic parameters.

    abstract::Coronary artery disease is frequently associated with disturbed blood lipids and with a deficient blood fibrinolytic capacity. In order to investigate a possible link between hypercholesterolemia and hypofibrinolysis, we have investigated the effect of simvastatin, a HMG-CoA reductase inhibitor, on blood lipids and fi...

    journal_title:Acta clinica Belgica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/17843286.1992.11718214

    authors: Jacobs H,Van de Werf F,Lesaffre E,De Geest H,Collen D

    更新日期:1992-01-01 00:00:00

  • Oral cephalosporins.

    abstract::The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections. The oldest ag...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1080/17843286.1992.11718259

    authors: Verhaegen J,Verbist L

    更新日期:1992-01-01 00:00:00

  • The immune reconstitution inflammatory syndrome: a cause of death in persons on antiretroviral therapy?

    abstract::The availability of antiretroviral therapy (ART) has significantly improved the quality of life of persons with HIV infection. However, new problems have arisen as a consequence of this treatment. An immune reconstitution inflammatory syndrome (IRIS) in which patients experience a paradoxical worsening of their clinic...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.3281

    authors: Huis in 't Veld D,Lukande R,Lammens M,Conesa-Botella A,Vlieghe E,Van Marck E,Pauwels P,Colebunders R

    更新日期:2013-07-01 00:00:00

  • Are ACE-inhibitors or ARB's still needed for cardiovascular prevention in high risk patients? Insights from profess and transcend.

    abstract::The HOPE and EUROPA clinical studies have shown that treatment with the angiotensin-converting enzyme (ACE) inhibitors, ramipril and perindopril, may reduce the occurrence of major cardiovascular events in patients with proven atherosclerotic disease. The recently published results of the PRoFESS and TRANSCEND trials ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,随机对照试验

    doi:10.1179/acb.2010.022

    authors: Van Mieghem W,Billiouw JM,Brohet C,Dupont AG,Gazagnes MD,Heller F,Krzesinski JM,Missault L,Persu A,Piérard L,Rottiers R,Vanhooren G,Vervaet P,Herman AG

    更新日期:2010-03-01 00:00:00

  • Q fever: a contemporary case series from a Belgian hospital.

    abstract:OBJECTIVES:Q fever is a global zoonosis that can cause both acute and chronic infections in humans through aerogenic transmission. Although Q fever was discovered already 80 years ago, this infectious disease remains largely unknown. We studied a case series in a Belgian tertiary care hospital. METHODS:A laboratory an...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2016.1165397

    authors: Vanderbeke L,Peetermans WE,Saegeman V,De Munter P

    更新日期:2016-10-01 00:00:00

  • Successful fibrinolytic treatment of prosthetic heart valve thrombosis using streptokinase.

    abstract:OBJECTIVES:This study aims to evaluate the clinical outcome of fibrinolytic treatment of prosthetic valve thrombosis (PVT) with 'streptokinase' as a first line treatment for these cases. METHODS:The study group was 20 consecutive patients (10 females) diagnosed with PVT. The protocol for streptokinase administration w...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/2295333714Y.0000000107

    authors: Sakr SA,Abdel-Shakour H,Ramadan MM

    更新日期:2015-06-01 00:00:00

  • Comparisons between psychotropic drugs: must the risk of side effects dictate our practices?

    abstract:OBJECTIVES:Recently, SOHO and CATIE's studies in the field of schizophrenic disorders asserted that molecules apparently showing the most side-effects are not only the most effective but also lead to the least changes in treatments. Can we generalise this assertion to other domains of pharmacological treatments, such a...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2008.043

    authors: Zdanowicz N,Jacques D,Reynaert C

    更新日期:2008-07-01 00:00:00

  • [Hypothalamic hypopituitarism with hyperphagia and subacute dementia due to neurosarcoidosis: case report and literature review].

    abstract::The frequency of neurologic involvement in sarcoidosis is about 5%. When the clinical picture presents with only neurological manifestations, as it did in our patient, the diagnosis at presentation is often difficult. Involvement of other tissues must therefore be actively searched. We describe a case of neurosarcoido...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1080/17843286.1992.11718250

    authors: Vanhoof J,Wilms G,Bouillon R

    更新日期:1992-01-01 00:00:00

  • The use of hypnosedative drugs in a university hospital setting.

    abstract:OBJECTIVE:The use of hypnosedatives (HSs) in the hospital and at home before admission was registered. Also, the incidence of HSs newly started in the hospital and the incidence of withdrawal in chronic users while in hospital was recorded. METHODS:The study population consisted of 517 consecutively admitted patients ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2003.58.4.003

    authors: Warie H,Petrovic M,Somers A,Mariman A,Robays H,Pevernagie D

    更新日期:2003-07-01 00:00:00

  • [Growth inhibition using estrogens in constitutionally tall girls].

    abstract::Estrogen treatment in high doses is effective in reducing adult stature in constitutionally tall girls. In this study, growth data of 38 normal girls with a predicted final height beyond 178 cm, are reported. They were treated with ethinyloestradiol in a daily dose of 0.200 mg until the epiphyseal plates were practica...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:

    authors: Du Caju MV,Bleyaert S,Op De Beeck L

    更新日期:1993-01-01 00:00:00

  • Pulmonary histiocytosis X diagnosed by bone biopsy. Report of a case.

    abstract::Histiocytosis X of the lung is associated with bone lesions in 4 to 20%. We report a case in which the diagnosis was missed in spite of repeated bronchoscopies with transbronchial lavage. The diagnosis was finally established by isotope bone scan, subsequent skeletal CT-scan and bone biopsy. ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.1994.11718372

    authors: Vandeurzen K,Delanote M,Verschakelen J,Sciot R,Decramer M

    更新日期:1994-01-01 00:00:00

  • The use of acetyl cholinesterase inhibitors and memantine in nursing home residents.

    abstract:AIM:Although a high proportion of elderly nursing home residents suffer from Alzheimer's disease (AD), data from the literature indicate that they are only rarely treated with Acetyl Cholinesterase Inhibitors (ChEls) or memantine. The aim of this study was to describe the use of ChEls or memantine by elderly residents ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,多中心研究

    doi:10.2143/ACB.66.5.2062587

    authors: Gorus E,Van Puyvelde K,Corremans V,Mets T

    更新日期:2011-09-01 00:00:00

  • Does serum 25 hydroxy vitamin D level predict disease activity in ulcerative colitis patients?

    abstract:BACKGROUND/AIM:There are controversial results regarding the relationship of serum 25 hydroxy vitamin D [25(OH)D] and ulcerative colitis (UC) activity. To address this issue, the current study was designed to evaluate the correlation of serum 25(OH)D level and disease activity in patients with UC. METHOD:All consecuti...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2015.1110895

    authors: Dolatshahi S,Pishgar E,Jamali R

    更新日期:2016-02-01 00:00:00

  • An inquiry on pain management in the emergency department of training hospitals.

    abstract:INTRODUCTION:Improving pain management in the ED might be attained by adequate teaching of medical students. We assessed the skills in pain treatment of ED physicians who teach the students. METHODS:All physicians working in an ED who provide elective training to undergraduate medical students from the Ghent Universit...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.66.6.2062603

    authors: Lemoyne S,De Paepe P,Vankeirsbilck C,Buylaert W

    更新日期:2011-11-01 00:00:00

  • 18-fluoro-deoxyglucose positron emission tomography may contribute to the diagnosis and follow-up of malakoplakia.

    abstract::Malakoplakia is a rare inflammatory disease involving most frequently the urinary tract. We present a case of bilateral renal malakoplakia, in which FDG-PET contributed to diagnosis. We made this diagnosis on the basis of clinical presentation, renal biopsy showing a mixed cellular infiltrate with granuloma formation ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2004.020

    authors: Vanbrabant P,Drieskens O,Blockmans D

    更新日期:2004-05-01 00:00:00

  • Mycobacterium marinum infection causing extensive tissue destruction in a hypoxic COPD patient.

    abstract::We report a skin Mycobacterium marinum infection presenting as wide ulcerative lesions of the arm (4 cm for the widest) in a hypoxic COPD patient who takes 4 mg methylprednisolone daily and higher doses during exacerbations. Diagnostic delay as well as glucocorticoid use could be responsible for the extension of the l...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.66.4.2062576

    authors: Buttafuoco F,Peché R,Vander Elst B,Van Meerhaeghe A

    更新日期:2011-07-01 00:00:00

  • [Cost effectiveness of vaccination against pneumococcal bacteremia in the elderly: the results in Belgium].

    abstract:BACKGROUND:Several studies have shown that pneumococcal vaccination of older persons would be cost-effective in preventing pneumococcal pneumonia, but evidence of clinical protection for this condition is uncertain. Given much better evidence of vaccination effectiveness against invasive disease, studies showing that v...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:

    authors: De Graeve D,Verhaegen J,Ament A,Baltussen R

    更新日期:2000-09-01 00:00:00

  • Multiple myeloma presenting as hepatic nodular lesion.

    abstract::The diffuse infiltration by plasma cells in the liver is not uncommon in multiple myeloma (MM). However, a MM with hepatic mass is very unusual. We report a case of a 75-year-old male with hepatomegaly and a lesion occupying a voluminous space in the liver. A lambda light chain multiple myeloma was found in the check-...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.67.5.2062696

    authors: de Vos M,Druez P,Nicaise M,Ngendahayo P,Sinapi I,Mineur P

    更新日期:2012-09-01 00:00:00

  • Post-transplant lymphoproliferative disorder after kidney transplantation: time to adopt monitoring of Epstein-Barr virus?

    abstract::Although post-transplant lymphoproliferative disorder is a classical complication encountered after kidney transplantation, its diagnosis can still be challenging and its outcome life-threatening. Most cases are related to Epstein-Barr virus (EBV) infection and occur mainly in the first year post-transplant, favoured ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/2295333714Y.0000000112

    authors: Biller P,Michaux L,Pauw LD,Camboni A,Mourad M,Kanaan N

    更新日期:2015-06-01 00:00:00

  • Thoracoscopic sympathicolysis for essential hyperhidrosis: immediate and one year follow-up results in 35 patients and review of the literature.

    abstract::Various treatments for essential hyperhidrosis are available. The aim of this study is to present our experience with a simplified thoracoscopic sympathicolysis technique in this disorder, and to confront our results with data in the literature, 35 consecutive patients (11 male, 24 female, age 12-44 years) with essent...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1080/22953337.1996.11718517

    authors: Noppen M,Vincken W,Dhaese J,Herregodts P,D'haens J

    更新日期:1996-01-01 00:00:00

  • Prevalence of vitamin K deficiency in older people with hip fracture.

    abstract::Introduction: Vitamin K plays an important role in blood coagulation. Diet is the main source of vitamin K and body stores are depleted in days, hence deficiency is common in malnourished older people. A high proportion of people who sustain a hip fracture are already malnourished, compounded by fasting for surgery wh...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2018.1564174

    authors: Bultynck C,Munim N,Harrington DJ,Judd L,Ataklte F,Shah Z,Dockery F

    更新日期:2020-04-01 00:00:00

  • Cardiovascular toxicity of cancer treatment.

    abstract::Drugs with potential cardiac toxicity are prominent in cancer treatment, not only the old chemotherapeutic agents, but also the newer targeted drugs and biologic agents. As the long-term survival of patients with malignancies has improved and cancer turned into a chronic disease, physicians must take into account the ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.66.4.2062566

    authors: Combes M,Rottey S,De Backer T

    更新日期:2011-07-01 00:00:00

  • Time course of iron metabolism in critically ill patients.

    abstract:BACKGROUND:Altered iron metabolism plays a central role in the development of anaemia in critically ill patients but the time course of iron status in septic and non-septic critically ill patients has not been well defined. METHODS:Prospective study in a 34-bed medico-surgical ICU. The complete blood count, iron, ferr...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.68.1.2062715

    authors: Piagnerelli M,Cotton F,Herpain A,Rapotec A,Chatti R,Gulbis B,Vincent JL

    更新日期:2013-01-01 00:00:00

  • Trichinella spiralis-associated myocarditis mimicking acute myocardial infarction.

    abstract::Background Trichinellosis is a parasitic infection caused by nematodes of the genus Trichinella, and its principal mode of transmission is the consumption of raw or undercooked contaminated meat. Cardiac involvement in trichinellosis is unusual, yet it represents the most frequent cause of death. Here, we report a cas...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2020.1790867

    authors: Mohib O,Clevenbergh P,Truyens C,Morissens M,Castro Rodriguez J

    更新日期:2020-07-04 00:00:00