Post-transplant lymphoproliferative disorder after kidney transplantation: time to adopt monitoring of Epstein-Barr virus?

Abstract:

:Although post-transplant lymphoproliferative disorder is a classical complication encountered after kidney transplantation, its diagnosis can still be challenging and its outcome life-threatening. Most cases are related to Epstein-Barr virus (EBV) infection and occur mainly in the first year post-transplant, favoured by the seronegative EBV status of the recipient transplanted with a kidney from a seropositive donor, and strong immunosuppression. We report the case of a young kidney-pancreas transplant recipient who developed post-transplant lymphoproliferative disorder (PTLD) early after transplantation, with a rapid fatal issue. We review the pathogenesis, clinical presentation, and management of PTLD with a focus on prevention.

journal_name

Acta Clin Belg

journal_title

Acta clinica Belgica

authors

Biller P,Michaux L,Pauw LD,Camboni A,Mourad M,Kanaan N

doi

10.1179/2295333714Y.0000000112

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

218-22

issue

3

eissn

1784-3286

issn

2295-3337

journal_volume

70

pub_type

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