Flow-assisted basophil activation tests in immediate drug hypersensitivity: two decades of Antwerp experience.

Abstract:

:The last two decades have witnessed that flow-assisted analysis of in vitro-activated basophils can constitute a valuable adjunct in the in vitro diagnostic approach of immediate drug hypersensitivity reactions (IDHR). This article summarises the current experience with the basophil activation test in the diagnosis of IDHR, with particular focus on allergy to curarising neuromuscular blocking agents, antibiotics (β-lactams and fluoroquinolones), iodinated radiocontrast media and opiates.

journal_name

Acta Clin Belg

journal_title

Acta clinica Belgica

authors

Mangodt EA,Van Gasse AL,Bastiaensen A,Decuyper II,Uyttebroek A,Faber M,Sabato V,Bridts CH,Hagendorens MM,De Clerck LS,Ebo DG

doi

10.1080/17843286.2015.1122871

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

19-25

issue

1

eissn

1784-3286

issn

2295-3337

journal_volume

71

pub_type

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