Abstract:
INTRODUCTION/BACKGROUND:The management of therapy-resistant lower urinary tract symptoms (LUTS) and symptoms resulting from pelvic organ dysfunctions are subject to a high variability in the Belgian health-care centres. Practical guidelines and standardized patient clinical care pathways are often lacking and unadapted to the Belgian healthcare system. OBJECTIVES:The OptiLUTS trial aims to improve the multidisciplinary care of therapy-resistant symptoms of the pelvis in the Belgian healthcare setting. Project A aims for the improvement of knowledge of 2nd line treatments for LUTS among general practitioners. In project B a treatment algorithm for the overactive bladder syndrome and non-obstructive urinary retention will be developed specifically for Belgium. In Project C a patient customized sacral neuromodulation (SNM) care pathway will be set up. METHODS:Part A: Explorative study among general practitioners by distribution of a questionnaire. Part B: Review of existing guidelines and use of the Delphi method to obtain expert consensus. Part C: A single center comparative study to compare outcomes before and after implementation of the SNM care pathway. Patients scheduled for the first stage of Interstim therapy™ will be included (N=100). Primary endpoints are the sensitivity and specificity of a new pelvic symptom assessment tool, the conversion to implant and explantation rates. CONCLUSION:There is a margin for improvement in the care process of patients with therapy-resistant symptoms of the pelvis in the Belgium healthcare system. In the OptiLUTs trial adapted guidelines and a clinical care pathway will be developed to standardize and increase the efficiency of care. TRIAL REGISTRATION:Approval for the trial by the Ethics Committee of the Ghent University hospital: EC/2018/0244.
journal_name
Acta Clin Belgjournal_title
Acta clinica Belgicaauthors
Ghijselings L,Van De Putte D,Hervé F,Goessaert AS,Beeckman D,Pattyn P,Everaert Kdoi
10.1080/17843286.2019.1630109subject
Has Abstractpub_date
2020-10-01 00:00:00pages
334-339issue
5eissn
1784-3286issn
2295-3337journal_volume
75pub_type
杂志文章abstract::We present a patient with therapy resistant multicentric reticulohistiocytosis (MRH). MRH is a rare granulomatous, multisystem disease characterised most frequently by disfiguring papulonodular skin lesions and sometimes a destructive polyarthritis, though any organ can be involved. Abnormal histiocytic reactions to a...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.66.1.2062520
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abstract::Various treatments for essential hyperhidrosis are available. The aim of this study is to present our experience with a simplified thoracoscopic sympathicolysis technique in this disorder, and to confront our results with data in the literature, 35 consecutive patients (11 male, 24 female, age 12-44 years) with essent...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/22953337.1996.11718517
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abstract::Parasitic infestations of the galdbladder and biliary tract are quite rare. Taenia saginata is an intestinal helmint and patients harbouring adult T.saginata tapeworms are mostly asymptomatic and discharge only fecal proglottids. In some cases there might be nonspecific symptoms like vomiting, nausea, epigastric pain,...
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abstract::Exhaustion of antigen-specific T-cells in order to escape immune destruction is frequently seen in chronic viral infection and different types of cancer. Blockade of overexpressed negative co-stimulatory pathways, a process known as immune checkpoint modulation, is a promising novel therapy that could improve the trea...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
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abstract::Temocillin, a methoxy-derivative of the broad-spectrum penicillin, ticarcillin, has been introduced into clinical practice in Belgium in 1988. Since then, not many surveys of its in vitro activity have been published. This study addresses this issue in a prospective collection of 300 consecutive Gram-negative isolates...
journal_title:Acta clinica Belgica
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doi:10.1179/acb.2001.053
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abstract::The National Institute for Insurance of Disease and Disablement (RIZIV/INAMI) in Belgium reimburses the costs of long term oxygen therapy (LTOT) by concentrators since 1984 and by liquid oxygen since 1988 for specific categories of patients supervised by approved medical centers. Since then we prescribed these therapi...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1995.11718439
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:Q fever is a global zoonosis that can cause both acute and chronic infections in humans through aerogenic transmission. Although Q fever was discovered already 80 years ago, this infectious disease remains largely unknown. We studied a case series in a Belgian tertiary care hospital. METHODS:A laboratory an...
journal_title:Acta clinica Belgica
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doi:10.1080/17843286.2016.1165397
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abstract::In comparing four currently available immunochemical methods for immunoglobulin quantification, i.e. radial immunodiffusion (RID), rate nephelometry (RN), laser nephelometry (LN) and turbidimetry (T), highly divergent results were obtained for monoclonal immunoglobulins. Comparison with data obtained by densitometric ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/22953337.1981.11718807
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:There has been an exponentially increasing interest in intraabdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) over the last decade, and different definitions have been suggested. Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect ou...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2007.62.s1.007
更新日期:2007-01-01 00:00:00
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journal_title:Acta clinica Belgica
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doi:10.1080/17843286.2018.1460019
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journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2009.037
更新日期:2009-05-01 00:00:00
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journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1994.11718357
更新日期:1994-01-01 00:00:00
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journal_title:Acta clinica Belgica
pub_type: 历史文章,杂志文章
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更新日期:2004-03-01 00:00:00
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journal_title:Acta clinica Belgica
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journal_title:Acta clinica Belgica
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更新日期:2019-04-01 00:00:00
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journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2016.1139288
更新日期:2016-08-01 00:00:00
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journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2015.1122872
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abstract::Histiocytosis X of the lung is associated with bone lesions in 4 to 20%. We report a case in which the diagnosis was missed in spite of repeated bronchoscopies with transbronchial lavage. The diagnosis was finally established by isotope bone scan, subsequent skeletal CT-scan and bone biopsy. ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1994.11718372
更新日期:1994-01-01 00:00:00
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journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2002.004
更新日期:2002-01-01 00:00:00
abstract::In humans, rabies still is a fatally evolving encephalomyelitis caused by a Rhabdovirus of the genus Lyssavirus. In general, the disease is contracted through a contact with an infected mammal. Taxonomically, different rabies and closely related rabies-like viruses can be distinguished. New molecular identification te...
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journal_title:Acta clinica Belgica
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journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
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pub_type: 杂志文章,实务指引
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更新日期:2018-08-01 00:00:00
abstract::Since the era of highly active antiretroviral therapy (HAART), HIV is considered a chronic disease. Adherence to HAART is crucial for effectiveness. Non-adherence negatively impacts patient outcome and the larger economy. However, data on adherence among the Belgian HIV cohort are scarce. Therefore, the purpose of thi...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
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journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/2295333714Y.0000000114
更新日期:2016-02-01 00:00:00
abstract::Infection with hepatitis B virus has become a vaccine-preventable disease. The recombinant hepatitis B vaccines available today are safe and immunogenic. In order for these vaccines to eradicate HBV a universal vaccination of neonates and/or children needs to be implemented. Major obstacles on the road to global hepat...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2001.032
更新日期:2001-07-01 00:00:00
abstract::Urinary schistosomiasis, caused by Schistosoma haematobium, is a prevalent parasitic infection in certain areas of Africa and the Middle East. Humans can be infected by cercariae when they are in contact with contaminated freshwater. The adult worms reside in the veins of the vesical and pelvis plexuses. The urinary b...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.3261
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:Although emergency department (ED) return visits are a significant problem universally, it has not been previously studied in our ED. The aim of this study was to determine the extent of the problem in our ED, to identify the relevant clinical predictor variables and to detect diagnostic errors. METHODS:A r...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2009.069
更新日期:2009-09-01 00:00:00
abstract::Drugs with potential cardiac toxicity are prominent in cancer treatment, not only the old chemotherapeutic agents, but also the newer targeted drugs and biologic agents. As the long-term survival of patients with malignancies has improved and cancer turned into a chronic disease, physicians must take into account the ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.66.4.2062566
更新日期:2011-07-01 00:00:00