Quantification of Monoclonal Immunoglobulins by Immunochemical and Densitometry Techniques.

Abstract:

:In comparing four currently available immunochemical methods for immunoglobulin quantification, i.e. radial immunodiffusion (RID), rate nephelometry (RN), laser nephelometry (LN) and turbidimetry (T), highly divergent results were obtained for monoclonal immunoglobulins. Comparison with data obtained by densitometric scanning (D) of the serum protein electrophoresis on cellulose acetate showed that these immunochemical techniques cannot be recommended for the quantification of monoclonal immunoglobulins, they may however remain useful for assessing relative changes in concentration during treatment.

journal_name

Acta Clin Belg

journal_title

Acta clinica Belgica

authors

Gorus F,Stesses S,Camp BV

doi

10.1080/22953337.1981.11718807

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

191-8

issue

4

eissn

1784-3286

issn

2295-3337

journal_volume

36

pub_type

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