Large granular lymphocyte proliferative disease: 21 Belgian cases and review of the literature.

Abstract:

:We report the findings in 21 Belgian patients (12 males and 9 females, median age 61 years) with LGLPD. Symptoms at presentation included infection (n = 9), weight loss (n = 5), asthenia (n = 9), pruritus (n = 2) and arthralgia (n = 7). Four patients were asymptomatic. The main clinical findings were hepatomegaly (n = 5), splenomegaly (n = 8), lymph node enlargement (n = 3) and arthritis (n = 5). All patients had an increased LGL count associated with anemia (n = 12), neutropenia (n = 17), often less than 0.5.10(9)/L (n = 10) and thrombocytopenia (n = 6). Three patterns of lymphocyte surface markers were observed: CD3+CD4-8+ (14 patients), CD3+CD4-8+ (5 patients) and CD3+CD4+8- (1 patient). An abnormal karyotype was found in 2 patients. T-cell receptor gene was rearranged in all cases tested (9/9).

journal_name

Acta Clin Belg

journal_title

Acta clinica Belgica

authors

Pierre PG,Bosly A,De Bock R,Debusscher L,Ferrant A,Feremans W,Lacor P,Michaux JL,Van Camp B,Van Hoof A

doi

10.1080/17843286.1992.11718206

keywords:

subject

Has Abstract,Author List Incomplete

pub_date

1992-01-01 00:00:00

pages

21-9

issue

1

eissn

1784-3286

issn

2295-3337

journal_volume

47

pub_type

杂志文章,评审
  • Microvesicular steatosis of the liver.

    abstract::The term "microvesicular steatosis of the liver" refers to a variant form of hepatic fat accumulation whose histologic features contrast with the much more common macrovesicular steatosis. Microvesicular steatosis of the liver was originally described in association with conditions who share a number of biochemical an...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1080/17843286.1990.11718105

    authors: Hautekeete ML,Degott C,Benhamou JP

    更新日期:1990-01-01 00:00:00

  • Malignant cardiac tamponade: safety and efficacy of intrapericardial bleomycin instillation.

    abstract:BACKGROUND:Malignant cardiac tamponade is a life-threatening condition that requires prompt treatment and effective management to prevent recurrence. This paper describes safety and efficacy outcomes after intrapericardial instillation of bleomycin as well as possible predictors of survival. METHODS:We performed a 10-...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2020.1790180

    authors: Defruyt L,Özpak E,Gevaert S,De Buyzere M,Vandecasteele E,De Pauw M,Tromp F

    更新日期:2020-07-05 00:00:00

  • Hypertension and the kidney.

    abstract::The kidney could be the cause of essential hypertension which can also cause renal disease. High blood pressure is also very common in chronic kidney disease, and is moreover a well-known risk factor for a faster progression of kidney failure. Hypertension and kidneys are thus closely linked. Hypertension must be aggr...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2007.002

    authors: Krzesinski JM,Cohen EP

    更新日期:2007-01-01 00:00:00

  • Atypical presentation of acute coronary syndrome (ACS): a case report.

    abstract:CASE:A 45-year-old man presented at the emergency department (ED) with stomach pain since eight days. The patient was not worried about his symptoms and requested only pain relief. The emergency physician requested a consult of the gastroenterologist. Clinical examination was unremarkable. However, 12-lead ECG and isch...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2018.1460019

    authors: Van Damme A,Vanderheeren P,De Backer T,Desimpel F

    更新日期:2018-12-01 00:00:00

  • Thymoma--an important differential diagnosis of mediastinal tumours.

    abstract::A 69-year-old man with slight dyspnoea underwent routine X-ray examination by his primary care physician. The X-ray and the CT showed a homogenous mass at the right side of the anterior mediastinum. The benignity and the origin of the tissue were still unknown. Therefore, we performed a CT-guided fine needle aspiratio...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.67.4.2062679

    authors: Michels G,Drebber U,Pfister R

    更新日期:2012-07-01 00:00:00

  • Management of refractory systemic rheumatic diseases.

    abstract::The management of refractory systemic rheumatic diseases remains a challenging issue. New immunosuppressive drugs have been developed which might improve long-term outcome, with a reasonably toxicity profile. Moreover, better understanding of the mechanisms underlying some of the systemic rheumatic disease has raised ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2003.58.5.009

    authors: Houssiau FA

    更新日期:2003-09-01 00:00:00

  • [Ketamine--dreams and realities].

    abstract::Ketamine is an anaesthetic used in human medicine and veterinary practice, synthesised on 1962 and marketed on 1970 in France. Recreational uses were described during 1992 in the medical community and in 1996 in the dance settings. The chemical name of ketamine is 2--(2chlorophenyl)2-(methylamine)-cyclohexanone, an ar...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:

    authors: Arditti J,Spadari M,de Haro L,Brun A,Bourdon JH,Valli M

    更新日期:2002-01-01 00:00:00

  • Time course of iron metabolism in critically ill patients.

    abstract:BACKGROUND:Altered iron metabolism plays a central role in the development of anaemia in critically ill patients but the time course of iron status in septic and non-septic critically ill patients has not been well defined. METHODS:Prospective study in a 34-bed medico-surgical ICU. The complete blood count, iron, ferr...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.68.1.2062715

    authors: Piagnerelli M,Cotton F,Herpain A,Rapotec A,Chatti R,Gulbis B,Vincent JL

    更新日期:2013-01-01 00:00:00

  • The abdominal compartment syndrome in patients with burn injury.

    abstract:INTRODUCTION:Intra-abdominal hypertension (IAH) and subsequent abdominal compartment syndrome (ACS) in burned patients is common. This sequence of events typically occurs in patients with larger burns receiving high volume fluid resuscitation. METHODS:A review of the literature was performed. The National Library of M...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2007.62.s1.017

    authors: Tuggle D,Skinner S,Garza J,Vandijck D,Blot S

    更新日期:2007-01-01 00:00:00

  • Infective endocarditis.

    abstract::The diagnosis of infective endocarditis remains difficult. The complication rate is very high. Serious complications may occur and the overall mortality is still 20-25%. The sooner the treatment is started, the better the final result. Antibiotic therapy is essential but cardiac surgery is frequently necessary. Early ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2008.085

    authors: Herregods MC,Hill E,Herijgers P,De Munter P,Vanderschueren S,Van Wijngaerden E,Peetermans WE

    更新日期:2008-11-01 00:00:00

  • Prevalence of vitamin K deficiency in older people with hip fracture.

    abstract::Introduction: Vitamin K plays an important role in blood coagulation. Diet is the main source of vitamin K and body stores are depleted in days, hence deficiency is common in malnourished older people. A high proportion of people who sustain a hip fracture are already malnourished, compounded by fasting for surgery wh...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2018.1564174

    authors: Bultynck C,Munim N,Harrington DJ,Judd L,Ataklte F,Shah Z,Dockery F

    更新日期:2020-04-01 00:00:00

  • Cause D'Erreur Dans La Lecture Des Antibiogrammes : Présence, Non Déclarée, D'Un Antiseptique Sur Les Disques.

    abstract::There is a need for legal control of sensitivity discs. False results are obtained by the use of discs containing an antibiotic and an unlabelled antimicrobial drug. Results of sensitivity tests (performed by the disc agar diffusion method) using Levocyclin8 discs furnished by the manufacturers were highly improbable....

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.1976.11717057

    authors: Yourassowsky E,Dony J,De Roeck A,De Keere V,Schoutens E,Vanderlinden MP,Palsterman V

    更新日期:1976-01-01 00:00:00

  • A woman with recurrent "infections" since birth--a new mevalonate kinase mutation.

    abstract::A tired 32-year-old woman complaining of tiredness was referred for work-up of a possible immune deficiency. She had a history of recurrent infections since birth, which usually responded to antibiotics within a few days. Her mother, a nurse, had reported that early charts had disappeared. Munchausen's by proxy was su...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.66.2.2062531

    authors: Farber CM,Wanders JA,Goffard JC,Parma J

    更新日期:2011-03-01 00:00:00

  • Analysis of paraphenylenediamine.

    abstract::The toxic Paraphenylenediamine is characterized by infrared spectrophotometry and nuclear magnetic resonance spectroscopy, whereas, high performance liquid chromatography with a refractive index detector was used to determine its purity in the suspect samples using external standardisation. An analytical method for de...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2006.068

    authors: Bellimam MA,Stambouli A,El Karni N,Bouayoun T,El Bouri A

    更新日期:2006-01-01 00:00:00

  • Subacute endocarditis due to Erysipelothrix rhusiopathiae.

    abstract::Erysipelothrix rhusiopathiae is a rare cause of endocarditis. Most cases were observed in people working with animals. We report a case in a 45-year old man without any exposure to animals. He was admitted to our hospital because of dyspnoea. Blood cultures were drawn following fever on day 8 of hospitalisation. Erysi...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2003.58.6.006

    authors: Spiritus T,Surmont I

    更新日期:2003-11-01 00:00:00

  • Calciphylaxis: a rare complication in alcoholic liver disease.

    abstract::Calciphylaxis, or calcific uremic arteriolopathy (CUA) is a rare but well described entity in patients with endstage renal disease (ESRD) and/or hyperparathyroidism. CUA is characterized by systemic acute calcification of the small and intermediate dermal vasculature that can lead to epidermal ischemia, ulceration, an...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.2863

    authors: Sermijn E,Strobbe T,Vandekerckhove L,Libbrecht L,Colle I,Schoonjans R,Vogelaers D

    更新日期:2013-03-01 00:00:00

  • Plasma D-dimer concentrations in different clinical conditions.

    abstract::D-dimers (DD), specific degradation products of crosslinked fibrin, are markers for activation of plasma coagulation and/or fibrinolysis. DD results below the cut-off level are proven to be useful to rule out the probable diagnosis of deep venous thrombosis (DVT) and/or pulmonary embolism (PE). Our objective was to de...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2002.060

    authors: Ver Elst K,Jochmans K,De Pauw A,De Waele M

    更新日期:2002-11-01 00:00:00

  • Doxycycline and hepatotoxicity.

    abstract::The hepatotoxicity of tetracyclines is well known. If microvesicular steatosis due to a high dose of tetracycline has virtually disappeared, it can also be observed with other drugs belonging to the tetracycline family. To our knowledge, hepatotoxicity induced by doxycycline has never been reported. In our patient, th...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.1992.11718230

    authors: Lienart F,Morissens M,Jacobs P,Ducobu J

    更新日期:1992-01-01 00:00:00

  • Consensus conference definitions and recommendations on intra-abdominal hypertension (iah) and the abdominal compartment syndrome (acs) - the long road to the final publications, how did we get there?

    abstract:OBJECTIVE:There has been an exponentially increasing interest in intraabdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) over the last decade, and different definitions have been suggested. Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect ou...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2007.62.s1.007

    authors: Malbrain ML,De Laet I,Cheatham M

    更新日期:2007-01-01 00:00:00

  • Pulmonary histiocytosis X diagnosed by bone biopsy. Report of a case.

    abstract::Histiocytosis X of the lung is associated with bone lesions in 4 to 20%. We report a case in which the diagnosis was missed in spite of repeated bronchoscopies with transbronchial lavage. The diagnosis was finally established by isotope bone scan, subsequent skeletal CT-scan and bone biopsy. ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.1994.11718372

    authors: Vandeurzen K,Delanote M,Verschakelen J,Sciot R,Decramer M

    更新日期:1994-01-01 00:00:00

  • A rare presentation of kidney failure in a patient with giant cell arteritis: case report and review of literature.

    abstract::Although giant cell arteritis, also called temporal arteritis, is the most common primary vasculitis in the elderly, an association with AA amyloidosis has rarely been reported. AA amyloidosis is a disorder that results from the extracellular deposition of proteolytic cleavage products of serum amyloid A, which occurs...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2020.1763671

    authors: Van De Ginste L,Dendooven A,Van Dorpe J,Delanghe JR,Vanmassenhove J,Speeckaert MM

    更新日期:2020-05-12 00:00:00

  • Analysis of foodborne disease in Belgium in 1997.

    abstract::Foodborne disease represents a major problem for public health in industrialized countries, albeit with a low lethality. Foodborne diseases are defined as a group of viral, bacterial or parasitic gastrointestinal infections transmitted by means of food. Proper food-hygiene practices and surveillance of individual dise...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1080/17843286.2000.11754316

    authors: Van Loock F,Ducoffre G,Dumont JM,Libotte-Chasseur ML,Imberechts H,Gouffaux M,Houins-Roulet J,Lamsens G,De Schrijver K,Bin N,Moreau A,De Zutter L,Daube G

    更新日期:2000-11-01 00:00:00

  • Relapse of a renal inflammatory pseudotumour associated with Wegener's granulomatosis.

    abstract::We report the case of a 32-year-old patient with Wegener's granulomatosis (WG) associated with a (biopsy - proven) renal inflammatory pseudotumour (IPT) of the left kidney treated by a partial nephrectomy, glucocorticoids and immunosuppressive drugs, in whom a relapse of renal IPT was found 6 years after the diagnosis...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2010.65.6.011

    authors: Vandergheynst F,Dumarey N,Cogan E

    更新日期:2010-11-01 00:00:00

  • Short-term return visits of 'general internal medicine' patients to the emergency department: extent and risk factors.

    abstract:OBJECTIVES:Although emergency department (ED) return visits are a significant problem universally, it has not been previously studied in our ED. The aim of this study was to determine the extent of the problem in our ED, to identify the relevant clinical predictor variables and to detect diagnostic errors. METHODS:A r...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2009.069

    authors: Vanbrabant P,Knockaert D

    更新日期:2009-09-01 00:00:00

  • Chain of rings: a radiographic sign of papillary thyroid cancer.

    abstract::Papillary thyroid cancer is the most common form of thyroid malignancy in children and adult with frequent metastases to the cervical lymph nodes. We present a case of metastatic papillary thyroid cancer with remarkable imaging findings of consecutive metastatic calcified lymph nodes resembling a chain of rings. While...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/2295333714Y.0000000084

    authors: Juan YH,Hsuan HF,Ng KK,Ng SH,Yu CW,Liu H,Lin YC

    更新日期:2015-04-01 00:00:00

  • The use of hypnosedative drugs in a university hospital setting.

    abstract:OBJECTIVE:The use of hypnosedatives (HSs) in the hospital and at home before admission was registered. Also, the incidence of HSs newly started in the hospital and the incidence of withdrawal in chronic users while in hospital was recorded. METHODS:The study population consisted of 517 consecutively admitted patients ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.1179/acb.2003.58.4.003

    authors: Warie H,Petrovic M,Somers A,Mariman A,Robays H,Pevernagie D

    更新日期:2003-07-01 00:00:00

  • [Hypothalamic hypopituitarism with hyperphagia and subacute dementia due to neurosarcoidosis: case report and literature review].

    abstract::The frequency of neurologic involvement in sarcoidosis is about 5%. When the clinical picture presents with only neurological manifestations, as it did in our patient, the diagnosis at presentation is often difficult. Involvement of other tissues must therefore be actively searched. We describe a case of neurosarcoido...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1080/17843286.1992.11718250

    authors: Vanhoof J,Wilms G,Bouillon R

    更新日期:1992-01-01 00:00:00

  • Hypothermia and Hodgkin's disease: case report and review of the literature.

    abstract::We reported the case of a patient with stage IV Hodgkin's disease (involving the nodes and Liver) presenting with paraneoplastic fever and who subsequently developed hypothermia during chemotherapy administration. We also reviewed the 12 other cases of hypothermia in Hodgkin's disease reported in the literature and di...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2006.042

    authors: Meert AP,Berghmans T,Sculier JP

    更新日期:2006-09-01 00:00:00

  • Prevalence of Bordetella holmesii and Bordetella bronchiseptica in respiratory tract samples from Belgian patients with pertussis-like symptoms by sensitive culture method and mass spectrometry.

    abstract::Insertion sequences IS481 and IS1001 are targets for molecular detection of respectively Bordetella pertussis and Bordetella parapertussis. There is a raising concern about specificity of these targets due to sequence similarity with Bordetella holmesii and Bordetella bronchiseptica. The likelihood of false (para)pert...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章

    doi:10.2143/ACB.3341

    authors: Van den Bossche D,De Bel A,De Smet D,Heylen O,Vekens E,Vandoorslaer K,Soetens O,Piérard D

    更新日期:2013-09-01 00:00:00

  • Nutritional problems in the elderly.

    abstract::Despite the high prevalence of malnutrition among elderly patients, nutritional problems are still not recognized as a priority forthem by health professionals. The need for nutritional assessment and intervention is particularly crucial in this age group, in whom the incidence of chronic illness is high and a myriad ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审

    doi:10.1179/acb.2009.017

    authors: Pepersack T

    更新日期:2009-03-01 00:00:00