Variation in medical resource utilisation in the management of pulmonary embolism in Belgium.


:The objective of this study was to investigate, through a patient chart analysis, the average and the variation in the medical resource use in pulmonary embolism (PE) patients in Belgium, and to find explanatory variables for the possible variation. A sample of patients with confirmed PE (n = 54) from 5 centres was selected. The centres were representative for size and region. The charts were selected at random after applying a set of exclusion criteria, in order to avoid heterogeneity of the sample characteristics. Charts were analysed using a standardised case report form, and medical resource use was collected by an independent researcher. Only medical resources related to the PE were included. On average, it appeared that the management of PE was fairly consistent between the different centres. The total average cost of PE was [symbol: see text] 3394 (St. Err. = [symbol: see text] 323). Nevertheless, large differences were found in the number of diagnostic and follow-up tests. Also, a wide variation in duration of hospital stay was found (average = 14.6, p75-p25 = 9.0), but this effect was not explained by the type of centre nor the region. The two factors that explain duration of hospital stay are the number of days of IV heparin use and the intensity of diagnostic follow-up, as expressed by the number of VQ-scans.


Acta Clin Belg


Acta clinica Belgica


Annemans L,Robays H,Bruart J,Verstraeten P





Has Abstract


2002-01-01 00:00:00












  • The use of hypnosedative drugs in a university hospital setting.

    abstract:OBJECTIVE:The use of hypnosedatives (HSs) in the hospital and at home before admission was registered. Also, the incidence of HSs newly started in the hospital and the incidence of withdrawal in chronic users while in hospital was recorded. METHODS:The study population consisted of 517 consecutively admitted patients ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Warie H,Petrovic M,Somers A,Mariman A,Robays H,Pevernagie D

    更新日期:2003-07-01 00:00:00

  • Atypical cause of radiculopathy - Intradural spinal arachnoid cyst.

    abstract::Intradural spinal arachnoid cysts are a relatively uncommon lesion that may be either intra, or extradural, and intradural spinal arachnoid cysts are even less common. Arachnoid cysts are cerebrospinal fluid collections in the spine that can present with neurological symptoms. The objective of this paper is to describ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Krstačić A,Krstačić G,Butković Soldo S

    更新日期:2016-08-01 00:00:00

  • Severity of liver echogenicity is correlated to serum c-peptide levels in type 2 diabetic patients.

    abstract:AIM:To investigate the correlation between liver echogenicity and serum C-peptide levels in type 2 diabetic patients treated with oral hypoglycaemic agents. PATIENTS AND METHODS:The study included 231 type 2 diabetic patients (114 men) with a mean age of 64.3 +/- 6.9 years and a mean diabetes duration of 8.5 +/- 3.2 y...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Papanas N,Symeonidis G,Mavridis G,Papazoglou D,Giannakis I,Papatheodorou K,Pastore F,Lakasas G,Maltezos E

    更新日期:2006-01-01 00:00:00

  • Time course of iron metabolism in critically ill patients.

    abstract:BACKGROUND:Altered iron metabolism plays a central role in the development of anaemia in critically ill patients but the time course of iron status in septic and non-septic critically ill patients has not been well defined. METHODS:Prospective study in a 34-bed medico-surgical ICU. The complete blood count, iron, ferr...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Piagnerelli M,Cotton F,Herpain A,Rapotec A,Chatti R,Gulbis B,Vincent JL

    更新日期:2013-01-01 00:00:00

  • Infective endocarditis.

    abstract::The diagnosis of infective endocarditis remains difficult. The complication rate is very high. Serious complications may occur and the overall mortality is still 20-25%. The sooner the treatment is started, the better the final result. Antibiotic therapy is essential but cardiac surgery is frequently necessary. Early ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Herregods MC,Hill E,Herijgers P,De Munter P,Vanderschueren S,Van Wijngaerden E,Peetermans WE

    更新日期:2008-11-01 00:00:00

  • Prevalence of Bordetella holmesii and Bordetella bronchiseptica in respiratory tract samples from Belgian patients with pertussis-like symptoms by sensitive culture method and mass spectrometry.

    abstract::Insertion sequences IS481 and IS1001 are targets for molecular detection of respectively Bordetella pertussis and Bordetella parapertussis. There is a raising concern about specificity of these targets due to sequence similarity with Bordetella holmesii and Bordetella bronchiseptica. The likelihood of false (para)pert...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Van den Bossche D,De Bel A,De Smet D,Heylen O,Vekens E,Vandoorslaer K,Soetens O,Piérard D

    更新日期:2013-09-01 00:00:00

  • A national cohort of HIV-infected patients in Belgium: design and main characteristics.

    abstract::In Belgium, individual laboratory and treatment data of all HIV-infected patients seen in the 9 AIDS Reference Centres and 7 AIDS Reference Laboratories are collected prospectively since 2006. We present here an analysis of patients recorded in the cohort database between 1st of January 2006 and 31st of December 2008....

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Van Beckhoven D,Buvé A,Ruelle J,Seyler L,Sasse A,Belgian HIV Cohort Study Group.

    更新日期:2012-09-01 00:00:00

  • Diagnosis and treatment of an unusual cause of sepsis in a diabetic patient: a Fournier's gangrene.

    abstract::Actually, the Fournier's gangrene is described as a dermohypodermitis of the perineal, genital and/or perianal regions which can affect both sexes and a wide range of ages. The diagnosis of the disease is essentially made on clinical grounds. Imagery can be interesting in case of an intra-abdominal suspected source of...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Maréchal R,Taccone F

    更新日期:2005-01-01 00:00:00

  • Durable response after VNCOP-B and rituximab in an elderly patient with high-grade B-cell lymphoma.

    abstract:OBJECTIVES AND METHODS: High-grade B-cell lymphoma, NOS (HGBL) have an aggressive clinical behavior and poor outcome using regimens currently employed for diffuse large B-cell lymphoma (DLBCL) such as rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). Promising results have been reported wi...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Cencini E,Fabbri A,Schiattone L,Gentili F,Mazzei MA,Bocchia M

    更新日期:2018-12-01 00:00:00

  • Liver perfusion and hepatocellular inflammatory response in sepsis.

    abstract::Sepsis is characterized by disturbances in liver perfusion and alterations in intrahepatic cellular functions and interactions. This provokes structural and functional liver damage as well as hepatocellular activation that is believed to perpetuate the immuno-inflammatory response. Changes in hepatic perfusion during ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Smets D,Spapen H,Diltoer M,Nguyen DN,Hubloue I,Huyghens L

    更新日期:1999-08-01 00:00:00

  • In vitro and in vivo evaluation of two factor VIII concentrates virally inactivated by solvent-detergent or by pasteurization.

    abstract::The present study compares two new factor VIII preparations currently used in the treatment of haemophilia. A Factor VIII was partially purified from plasma obtained from unpaid voluntary Belgian donors in the blood transfusion centers of Lille and Amsterdam and virus-inactivated by exposure to solvent-detergent (FVII...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Peerlinck K,Arnout J,Tamise M,Vanherle A,Fondu P,Vermylen J

    更新日期:1991-01-01 00:00:00

  • Kidney in old age.

    abstract::Epidemiological studies have shown that chronic kidney disease (CKD) is a major health problem especially in an older population. Given the growing segment of the elderly population and the important implication of renal disease on health care, this review discusses the structural and functional changes of the ageing ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Maertens S,Van Den Noortgate NJ

    更新日期:2008-01-01 00:00:00

  • Type 1 (insulin-dependent) diabetes mellitus: an autoimmune, predictable and preventable disease? Lessons from national registries and new challenges to clinical biology.

    abstract::Type 1 (insulin-dependent) diabetes mellitus is a frequent chronic disease that affects children as well as adults. The disease keeps a life-long burden on patients, their environment and society. Although still incompletely understood, its pathogenesis becomes progressively unravelled. Autoimmune phenomena play an im...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Gorus FK,Anselmo J,Keymeulen B

    更新日期:1993-01-01 00:00:00

  • Calciphylaxis: a rare complication in alcoholic liver disease.

    abstract::Calciphylaxis, or calcific uremic arteriolopathy (CUA) is a rare but well described entity in patients with endstage renal disease (ESRD) and/or hyperparathyroidism. CUA is characterized by systemic acute calcification of the small and intermediate dermal vasculature that can lead to epidermal ischemia, ulceration, an...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Sermijn E,Strobbe T,Vandekerckhove L,Libbrecht L,Colle I,Schoonjans R,Vogelaers D

    更新日期:2013-03-01 00:00:00

  • Role of hepatic arterial embolisation in the treatment for metastatic insulinoma. Report of two cases and review of the literature.

    abstract::Malignant insulinomas are very rare. They have typical clinical and biochemical characteristics that allow an early detection and distinction from other sorts of islet cell carcinoma. As a result a curative resection can occasionally be managed. Nevertheless, for more advanced stages the same treatment options as for ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Berwaerts J,Verhelst J,Hubens H,Kunnen J,Schrijvers D,Joosens E,Mahler C,Van Gaal L

    更新日期:1997-01-01 00:00:00

  • Approach to and management of abnormalities in plasma sodium.

    abstract::The differential diagnosis between hypertonic, isotonic and hypotonic hyponatremia are presented. The help of some usual serum (urea, uric acid and TCO2) and urine parameters (mainly osmolality and sodium concentration) are discussed and help to determine the best treatment. Morbidity associated with untreated hyponat...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Decaux G

    更新日期:2019-02-01 00:00:00

  • The immune reconstitution inflammatory syndrome: a cause of death in persons on antiretroviral therapy?

    abstract::The availability of antiretroviral therapy (ART) has significantly improved the quality of life of persons with HIV infection. However, new problems have arisen as a consequence of this treatment. An immune reconstitution inflammatory syndrome (IRIS) in which patients experience a paradoxical worsening of their clinic...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Huis in 't Veld D,Lukande R,Lammens M,Conesa-Botella A,Vlieghe E,Van Marck E,Pauwels P,Colebunders R

    更新日期:2013-07-01 00:00:00

  • Posterior reversible encephalopathy syndrome: a rare neurological manifestation in Von Hippel-Lindau disease.

    abstract::We report on a 34-year-old woman, who was recently diagnosed with Von Hippel-Lindau disease (VHL), genetically confirmed. At this moment, she presented with an acute history of arterial hypertension, headache, cortical blindness and epilepsy. On the basis of clinical and magnetic resonance imaging (MRI) criteria the d...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Vanacker P,Vanacker A,Leys A,Thijs V

    更新日期:2010-07-01 00:00:00

  • Long-term effects of gastric bypass surgery on psychosocial well-being and eating behavior: not all that glitters is gold.

    abstract:OBJECTIVES:The aim of this pilot study was to evaluate long-term effects of Roux-en-Y gastric bypass (RYGB) on physical and psychosocial health as well as eating behavior of obese patients. METHODS:We compared 23 patients 7 years after RYGB to 23 body mass index (BMI), sex, and age matched obese control patients by me...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Vangoitsenhoven R,Frederiks P,Gijbels B,Lannoo M,Van der Borght W,Van den Eynde A,Mertens A,Mathieu C,Van der Schueren B

    更新日期:2016-12-01 00:00:00

  • Consensus conference definitions and recommendations on intra-abdominal hypertension (iah) and the abdominal compartment syndrome (acs) - the long road to the final publications, how did we get there?

    abstract:OBJECTIVE:There has been an exponentially increasing interest in intraabdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) over the last decade, and different definitions have been suggested. Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect ou...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Malbrain ML,De Laet I,Cheatham M

    更新日期:2007-01-01 00:00:00

  • [Hypothalamic hypopituitarism with hyperphagia and subacute dementia due to neurosarcoidosis: case report and literature review].

    abstract::The frequency of neurologic involvement in sarcoidosis is about 5%. When the clinical picture presents with only neurological manifestations, as it did in our patient, the diagnosis at presentation is often difficult. Involvement of other tissues must therefore be actively searched. We describe a case of neurosarcoido...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Vanhoof J,Wilms G,Bouillon R

    更新日期:1992-01-01 00:00:00

  • Epidemiology of AKI in the ICU.

    abstract::Up to a little while ago there was no uniform definition for acute kidney injury (AKI). Recently, the Acute Dialysis Quality Initiative proposed the RIFLE consensus classification for AKI. This classification was adapted and modified by the Acute Kidney Injury Network into the AKI staging system. This classification d...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Hoste EA,De Corte W

    更新日期:2007-01-01 00:00:00

  • Campylobacter fetus subspecies fetus infection of an abdominal aneurysm.

    abstract::We report a case of aneurysm of the abdominal aorta with spontaneous rupture in a 64-year-old man with emphysema and chronic alcoholism. Campylobacter fetus subspecies fetus was repeatedly recovered from the blood and from specimens of the excised aneurysm. The patient died in spite of early diagnosis, intravenous ery...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Jacobs J,Van Lierde J,Nevelsteen A,Vermylen J,Verbist L

    更新日期:1989-01-01 00:00:00

  • Management of acute ischaemic stroke.

    abstract::Over the past few years there have been enormous changes in the management of stroke patients. General practitioners, ambulance personnel/paramedics and the general public need to be well informed that stroke is a medical emergency. Prevention of secondary brain damage by normalising vital parameters and combating fev...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: De Keyser J,Sulter G,Langedijk M,Elting JW,van der Naalt J

    更新日期:1999-10-01 00:00:00

  • Molecular profiling in lung cancer associated with cystic airspaces.

    abstract::'Lung cancer associated with cystic airspaces' is a rare radiological entity that is more frequently encountered on imaging studies and is gaining more attention since the widespread use of CT for lung cancer screening. Numerous aspects of this entity remain unraveled, including molecular profiling. The goal of this o...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Snoeckx A,Reyntiens P,Pauwels P,Van Schil PE,Parizel PM,Van Meerbeeck JP

    更新日期:2019-10-15 00:00:00

  • Nonalcoholic steatohepatitis and insulin resistance: interface between gastroenterologists and endocrinologists.

    abstract::Nonalcoholic steatohepatitis (NASH), along with other forms of nonalcoholic fatty liver disease, is an increasingly common clinico-pathological syndrome. It is frequently associated with obesity, especially visceral fat, and type 2 diabetes, and is intimately related to markers of the insulin resistance syndrome. Both...

    journal_title:Acta clinica Belgica

    pub_type: 社论


    authors: Scheen AJ,Luyckx FH

    更新日期:2003-03-01 00:00:00

  • Reversible splenial lesion in auto-immune thyroid disease: a case report.

    abstract::Reversible lesions of the splenium of the corpus callosum constitute a clinicoradiological syndrome that has been associated to various medical conditions. We report the case of a 47-year-old man who presented with encephalopathy associated to auto-immune thyroid disease in which a reversible splenial lesion was isola...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: De Greef J,Jaumotte C,Quivron B,Derue G

    更新日期:2014-06-01 00:00:00

  • The haemophagocytic syndrome.

    abstract::The haemophagocytic syndrome or haemophagocytic lymphohistiocytosis (HLH) is a syndrome encompassing a heterogeneous group of disorders characterized by a persistent activation of benign macrophages, leading to uncontrolled secretion of cytokines and phagocytosis of blood cells. The syndrome can be primary due to muta...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章,评审


    authors: Dierickx D,Cortoos A,Vanderschueren S

    更新日期:2011-11-01 00:00:00

  • Simultaneous determination of seven azole antifungal drugs in serum by ultra-high pressure liquid chromatography and diode array detection.

    abstract::Azole antifungals are a group of fungistatic agents that can be administered orally or parenterally. The determination of the concentrations of these antifungals (miconazole, fluconazole, ketoconazole, posaconazole, voriconazole, itraconazole, and its major active metabolite, hydroxy-itraconazole) in serum can be usef...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Mistretta V,Dubois N,Denooz R,Charlier C

    更新日期:2014-01-01 00:00:00

  • Postprandial reactive hypoglycaemia in a very old patient.

    abstract:OBJECTIVE AND IMPORTANCE:Postprandial reactive hypoglycaemia (PRH) is a clinical syndrome characterized by the recurrence of symptomatic hypoglycaemia during postprandial periods. PRH remains a diagnostic challenge for clinicians, because of its atypical manifestations and low prevalence, especially in older persons. ...

    journal_title:Acta clinica Belgica

    pub_type: 杂志文章


    authors: Deliens C,Losseau C,Vandeleene B,Boland B

    更新日期:2014-08-01 00:00:00