Abstract:
:Diabetes registries have documented that the lifetime risk of diabetes amounts to at least 10% in the western world. Moreover the prevalence of type 2 diabetes is increasing worldwide especially in developing countries. Furthermore there is a secular trend toward earlier clinical manifestation of both type 1 and type 2 diabetes. In the absence of a permanent cure for primary diabetes the present estimated number of at least 150 million diabetic patients worldwide is expected to double within the next 20 years. Consequently a sharp increase in the global burden of chronic diabetes complications is to be feared in the coming decades. Therefore it is absolutely mandatory to intensify research efforts aiming at identifying the etiological factors involved and designing effective strategies for prediction and prevention of the disease and its devastating complications. Diabetes registries constitute instruments of choice to conduct such studies because they are able to collect standardised clinical, demographic and biological information from sufficiently large representative groups of patients and risk groups such as first degree relatives. Since 1989, the Belgian Diabetes Registry is studying all types of diabetes presenting before age 40 in Belgium and provides a paradigm of how diabetes registries may also contribute to the advancement of knowledge on disease heterogeneity, etiology, prediction and prevention.
journal_name
Acta Clin Belgjournal_title
Acta clinica Belgicaauthors
Gorus FK,Weets I,Couck P,Pipeleers DG,Belgian Diabetes Registry.doi
10.1179/acb.2004.001keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
1-13issue
1eissn
1784-3286issn
2295-3337journal_volume
59pub_type
杂志文章,评审abstract::Insight into the fundamental physiological mechanisms of blood vessel development and neoformation has led to the discovery of multiple angiogenic growth factors and inhibitors. To date, at least 5 angiogenesis inhibitors are readily available for clinical use, mainly in the treatment of cancers and age-related macula...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2007.027
更新日期:2007-05-01 00:00:00
abstract::We present the case of a 51-year-old woman who presented a right supraclavicular mass corresponding to lymphadenitis with atypical mycobacterium (Mycobacterium genavense). Later, she developed subcutaneous purulent small nodules containing the same germ. The presence of this mycobacterium was in the context of recurre...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/0001551213Z.00000000016
更新日期:2014-04-01 00:00:00
abstract::Papillary thyroid cancer is the most common form of thyroid malignancy in children and adult with frequent metastases to the cervical lymph nodes. We present a case of metastatic papillary thyroid cancer with remarkable imaging findings of consecutive metastatic calcified lymph nodes resembling a chain of rings. While...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333714Y.0000000084
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The use of hypnosedatives (HSs) in the hospital and at home before admission was registered. Also, the incidence of HSs newly started in the hospital and the incidence of withdrawal in chronic users while in hospital was recorded. METHODS:The study population consisted of 517 consecutively admitted patients ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2003.58.4.003
更新日期:2003-07-01 00:00:00
abstract::A tired 32-year-old woman complaining of tiredness was referred for work-up of a possible immune deficiency. She had a history of recurrent infections since birth, which usually responded to antibiotics within a few days. Her mother, a nurse, had reported that early charts had disappeared. Munchausen's by proxy was su...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.66.2.2062531
更新日期:2011-03-01 00:00:00
abstract::We report about 2 cases of isolated mediastinal tuberculous lymphadenitis presenting without parenchymal infiltrates. Although rare, this mode of presentation reminds the clinician that tuberculosis has to be included in the differential diagnosis of mediastinal masses even in the absence of parenchymal lesion. Both c...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1998.11754153
更新日期:1998-04-01 00:00:00
abstract::Allogeneic hematopoietic stem cell transplantation (HSCT) is used for the treatment of selected hematological malignancies. Its curative potential is based on two very different mechanisms, involving the conditioning regimen and the graft-versus-host reactions, respectively. The high-dose chemo-radiotherapy conditioni...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2003.58.1.005
更新日期:2003-01-01 00:00:00
abstract::We report on a 34-year-old woman, who was recently diagnosed with Von Hippel-Lindau disease (VHL), genetically confirmed. At this moment, she presented with an acute history of arterial hypertension, headache, cortical blindness and epilepsy. On the basis of clinical and magnetic resonance imaging (MRI) criteria the d...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2010.060
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION/BACKGROUND:The management of therapy-resistant lower urinary tract symptoms (LUTS) and symptoms resulting from pelvic organ dysfunctions are subject to a high variability in the Belgian health-care centres. Practical guidelines and standardized patient clinical care pathways are often lacking and unadapted...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2019.1630109
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:There has been an exponentially increasing interest in intraabdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) over the last decade, and different definitions have been suggested. Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect ou...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2007.62.s1.007
更新日期:2007-01-01 00:00:00
abstract::After notification of a case of fulminant hepatitis B virus (HBV) infection in a 83-year-old female resident of a nursing home to the Flemish Health Inspectorate, a seroepidemiological study and a retrospective cohort study were conducted among the 94 residents and 47 nursing staff to assess the extent of HBV transmis...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2005.012
更新日期:2005-03-01 00:00:00
abstract::Pregnancy is a cardiovascular and metabolic challenge to the human female body. This review summarizes current knowledge on the regulation of blood pressure and plasma volume in normal and hypertensive pregnant women. During pregnancy, systemic vascular resistance and blood pressure decrease, whereas cardiac output an...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2010.050
更新日期:2010-07-01 00:00:00
abstract::The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections. The oldest ag...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/17843286.1992.11718259
更新日期:1992-01-01 00:00:00
abstract::Various treatments for essential hyperhidrosis are available. The aim of this study is to present our experience with a simplified thoracoscopic sympathicolysis technique in this disorder, and to confront our results with data in the literature, 35 consecutive patients (11 male, 24 female, age 12-44 years) with essent...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/22953337.1996.11718517
更新日期:1996-01-01 00:00:00
abstract::We report the case of a 32-year-old patient with Wegener's granulomatosis (WG) associated with a (biopsy - proven) renal inflammatory pseudotumour (IPT) of the left kidney treated by a partial nephrectomy, glucocorticoids and immunosuppressive drugs, in whom a relapse of renal IPT was found 6 years after the diagnosis...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2010.65.6.011
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVES:Recently, SOHO and CATIE's studies in the field of schizophrenic disorders asserted that molecules apparently showing the most side-effects are not only the most effective but also lead to the least changes in treatments. Can we generalise this assertion to other domains of pharmacological treatments, such a...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2008.043
更新日期:2008-07-01 00:00:00
abstract::Non-closure of abdominal fascia and the resultant open abdomen after laparotomy has become a major advance in the management of critically ill or injured patients. The benefits of open abdomen are many and include the prevention of intra-abdominal hypertension and the consequent abdominal compartment syndrome. Appropr...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2007.62.s1.027
更新日期:2007-01-01 00:00:00
abstract::Cystic fibrosis (CF) is one of the most common hereditary lung diseases. Pseudomonas aeruginosa (PA), Aspergillus fumigatus (AF) and Candida albicans (CA) are the principal bacterial and fungal pathogens in the airways of CF patients. The interactions of coexisting bacterial-fungal pathogens are of great interest. In ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2020.1852850
更新日期:2020-11-26 00:00:00
abstract:OBJECTIVES:This study aims to evaluate the clinical outcome of fibrinolytic treatment of prosthetic valve thrombosis (PVT) with 'streptokinase' as a first line treatment for these cases. METHODS:The study group was 20 consecutive patients (10 females) diagnosed with PVT. The protocol for streptokinase administration w...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333714Y.0000000107
更新日期:2015-06-01 00:00:00
abstract::We compared the technique of immunofluorescence on clinical samples (IFCS) and immunofluorescence on centrifuged cell cultures (IFCC) for the detection of respiratory viruses, using monoclonal antibodies. Four hundred fourty five nasopharyngeal aspirates were tested prospectively for RSV, influenza- (A and B), parainf...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1991.11718134
更新日期:1991-01-01 00:00:00
abstract::Foodborne disease represents a major problem for public health in industrialized countries, albeit with a low lethality. Foodborne diseases are defined as a group of viral, bacterial or parasitic gastrointestinal infections transmitted by means of food. Proper food-hygiene practices and surveillance of individual dise...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2000.11754316
更新日期:2000-11-01 00:00:00
abstract::The toxic Paraphenylenediamine is characterized by infrared spectrophotometry and nuclear magnetic resonance spectroscopy, whereas, high performance liquid chromatography with a refractive index detector was used to determine its purity in the suspect samples using external standardisation. An analytical method for de...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2006.068
更新日期:2006-01-01 00:00:00
abstract::Reversible lesions of the splenium of the corpus callosum constitute a clinicoradiological syndrome that has been associated to various medical conditions. We report the case of a 47-year-old man who presented with encephalopathy associated to auto-immune thyroid disease in which a reversible splenial lesion was isola...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333713Y.0000000002
更新日期:2014-06-01 00:00:00
abstract::The patient in this report was diagnosed simultaneously with primary biliary cirrhosis (PBC), spondyloarthritis, and generalized morphea and was started on infliximab therapy. In addition to an improvement in clinical symptoms with this therapy, an improvement was also observed in laboratory parameters such as cholest...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2017.1290567
更新日期:2017-10-01 00:00:00
abstract::Background: Metastatic clear-cell renal cell carcinoma (m-ccRCC) patients with bone metastases (BM) treated with vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKI) have a poorer outcome compared to patients without BM. We aimed to investigate whether an increased incidence of VEGFR-TK...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2018.1551744
更新日期:2019-12-01 00:00:00
abstract::Prototheca zopfii, an alga-like organism, was isolated from subungual material in a patient with onycholysis. This organism seldom causes human infections. Clinical and laboratory aspects are described. The literature is reviewed. ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/17843286.1991.11718171
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Sarcoidosis is a multisystem inflammatory disorder of unknown etiology. It is characterized by the presence of noncaseating granulomas and an inflammatory process in which T lymphocytes, especially type-1 helper T (Th1) cells, macrophages and different cytokines are involved. Different studies ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2016.1152671
更新日期:2016-12-01 00:00:00
abstract::We report and discuss the case of a 51-year-old patient undergoing elective laparoscopic surgery for pheochromocytoma after 10 days of medical pre-treatment. After anaesthetic induction, a deep level of anaesthesia could not prevent the onset of repeated hypertensive peaks, followed by severe hypotensive periods. Once...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333715Y.0000000069
更新日期:2016-06-01 00:00:00
abstract::Significant visceral edema associated with massive fluid resuscitation, paralytic ileus and formation of pancreatic ascites in patients with severe acute pancreatitis (SAP) can lead to abdominal compartment syndrome (ACS) that can contribute to the early development of multiple organ dysfunction syndrome (MODS), espec...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::We report a case of aneurysm of the abdominal aorta with spontaneous rupture in a 64-year-old man with emphysema and chronic alcoholism. Campylobacter fetus subspecies fetus was repeatedly recovered from the blood and from specimens of the excised aneurysm. The patient died in spite of early diagnosis, intravenous ery...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/17843286.1989.11717999
更新日期:1989-01-01 00:00:00