Abstract:
:A 12-year-old African girl presented with multiple, sharply bordered hyperpigmented patches predominantly on the dorsal, tip and lateral aspects of the tongue since 1 year (Figs 1 and 2). On clinical examination, we found an obese adolescent girl with a BMI: 26.5 kg/m(2) ( > P97) with acanthosis nigricans of the neck. No medications were taken. Vitamin B12, liver tests and kidney function were normal. There was a decreased serum iron, 25OH vitamin D and zinc. Hyperinsulinism and heterozygosity for HbS (32%) were detected. Menarche: 12 years. No other family members were known with this anomaly.
journal_name
Acta Clin Belgjournal_title
Acta clinica Belgicaauthors
Karine Francine Docx M,Vandenberghe P,Govaert Pdoi
10.1179/2295333715Y.0000000067subject
Has Abstractpub_date
2016-04-01 00:00:00pages
117-8issue
2eissn
1784-3286issn
2295-3337journal_volume
71pub_type
杂志文章abstract::Background and aim: Nontraumatic intracerebral hemorrhage (ICH) remains a devastating disease for high in-hospital and long-term mortality and residual neurological disability. The aim of our study was to analyze the prognostic factors in patients managed for ICH in the real-life clinical practice.Materials and Method...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2020.1750151
更新日期:2020-04-12 00:00:00
abstract::In order to demonstrate an intake of cannabis, there are a number of rapid tests, all of them being focused on urine. In this study, we evaluated the results of six tests when applied to sweat (DrugWipe), saliva and urine (Syva Rapidtest, Biomedix, Frontline, DrugWipe, Cortez Dako). Fifty regular users of cannabis and...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::We report on a 34-year-old woman, who was recently diagnosed with Von Hippel-Lindau disease (VHL), genetically confirmed. At this moment, she presented with an acute history of arterial hypertension, headache, cortical blindness and epilepsy. On the basis of clinical and magnetic resonance imaging (MRI) criteria the d...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2010.060
更新日期:2010-07-01 00:00:00
abstract::Insertion sequences IS481 and IS1001 are targets for molecular detection of respectively Bordetella pertussis and Bordetella parapertussis. There is a raising concern about specificity of these targets due to sequence similarity with Bordetella holmesii and Bordetella bronchiseptica. The likelihood of false (para)pert...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.3341
更新日期:2013-09-01 00:00:00
abstract::Ketamine is an anaesthetic used in human medicine and veterinary practice, synthesised on 1962 and marketed on 1970 in France. Recreational uses were described during 1992 in the medical community and in 1996 in the dance settings. The chemical name of ketamine is 2--(2chlorophenyl)2-(methylamine)-cyclohexanone, an ar...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::P-glycoprotein, a pump located in the plasma cell membrane, extrudes several clinically important drugs from the cell, and hence causes multidrug resistance. Reversing clinical drug resistance is possible by using agents that inhibit the activity of P-glycoprotein. We describe the results of sequential flow cytometric...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2000.11754299
更新日期:2000-07-01 00:00:00
abstract::We describe a case of acquired hepatocerebral degeneration (AHD) presenting with confusion and worsening memory problems since her discharge from the gastroenterology units. Cases of AHD are rare and are frequently confused with hepatic encephalopathy and Wilson's disease. There are no proven pharmacological therapies...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333715Y.0000000027
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of one year continuous positive airway pressure (CPAP) treatment on metabolic syndrome (MS) prevalence and components in patients diagnosed with both obstructive sleep apnea syndrome (OSAS) and metabolic syndrome. METHODS:This was a single center, observational prospective cohort st...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2009.051
更新日期:2009-07-01 00:00:00
abstract::The management of refractory systemic rheumatic diseases remains a challenging issue. New immunosuppressive drugs have been developed which might improve long-term outcome, with a reasonably toxicity profile. Moreover, better understanding of the mechanisms underlying some of the systemic rheumatic disease has raised ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2003.58.5.009
更新日期:2003-09-01 00:00:00
abstract::Significant visceral edema associated with massive fluid resuscitation, paralytic ileus and formation of pancreatic ascites in patients with severe acute pancreatitis (SAP) can lead to abdominal compartment syndrome (ACS) that can contribute to the early development of multiple organ dysfunction syndrome (MODS), espec...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Tramadol is a weak opioid with effects on adrenergic and serotonergic neurotransmission that is used to treat cancer pain and chronic non malignant pain. This drug was initiated in association with paroxetine and dosulepine hydrochloride in a tetraparetic patient with chronic pain. Fifty-six days after initiation of t...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1996.11718509
更新日期:1996-01-01 00:00:00
abstract::Elevated intra-abdominal pressure (IAP) exerts effects not only on intra-abdominal organs, but also on organs distant to the abdominal compartment. Abdomino-thoracic interaction during intra-abdominal hypertension (IAH) or abdominal compartment syndrome (ACS) interferes with pulmonary, cardiovascular and cerebral func...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract::We report the case of a 32-year-old patient with Wegener's granulomatosis (WG) associated with a (biopsy - proven) renal inflammatory pseudotumour (IPT) of the left kidney treated by a partial nephrectomy, glucocorticoids and immunosuppressive drugs, in whom a relapse of renal IPT was found 6 years after the diagnosis...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2010.65.6.011
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:In many health care systems, strategies are currently deployed to engage patients and other stakeholders in decisions affecting hospital services. In this paper, a model for stakeholder involvement is presented and evaluated in three Flemish hospitals. In the model, a stakeholder committee advises the hosp...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2016.1246681
更新日期:2017-02-01 00:00:00
abstract::A multidisciplinary pulmonary rehabilitation program has become an important part of the treatment of chronic obstructive pulmonary disease. It can improve both exercise tolerance and health related quality of life in these patients. Exercise training has to be included for the program to be successful. The intensity ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2010.071
更新日期:2010-09-01 00:00:00
abstract::Background Evidence of diagnostic accuracy for proposed definitions of nocturnal polyuria is currently unclear. Purpose Systematic review to determine population-based evidence of the diagnostic accuracy of proposed definitions of nocturnal polyuria based on data from frequency-volume charts. Methods Seventeen pre-spe...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2018.1427821
更新日期:2018-08-01 00:00:00
abstract::We have studied the clinical characteristics of 126 insulin-treated diabetic patients, mainly type I subjects, who regularly performed during 18 months home glucose monitoring. The numbers of strips used each month was of 60 +/- 33 (mean +/- lSD). During the study period, HbA1C levels decreased from 8.6 +/- 2.1 to 7.0...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1993.11718324
更新日期:1993-01-01 00:00:00
abstract::After notification of a case of fulminant hepatitis B virus (HBV) infection in a 83-year-old female resident of a nursing home to the Flemish Health Inspectorate, a seroepidemiological study and a retrospective cohort study were conducted among the 94 residents and 47 nursing staff to assess the extent of HBV transmis...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2005.012
更新日期:2005-03-01 00:00:00
abstract::Coronary artery disease is frequently associated with disturbed blood lipids and with a deficient blood fibrinolytic capacity. In order to investigate a possible link between hypercholesterolemia and hypofibrinolysis, we have investigated the effect of simvastatin, a HMG-CoA reductase inhibitor, on blood lipids and fi...
journal_title:Acta clinica Belgica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/17843286.1992.11718214
更新日期:1992-01-01 00:00:00
abstract::As a result of the St Vincent declaration, a Belgian "task force" was installed in 1992 and consequently 16 working groups were formed. They presented their objectives in 1995. The working group "prevention and treatment of diabetic foot lesions" started the implementation of a screening program to obtain an overview ...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,多中心研究
doi:10.1179/acb.2001.005
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:Pain acceptance is considered important for mental well-being with better functional outcomes for chronic pain patients. The present study explored whether pain-related variables (pain severity, pain interference, pain duration, and pain catastrophizing) and non-pain-related variables (personality traits) inf...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.2143/ACB.66.3.2062549
更新日期:2011-05-01 00:00:00
abstract::Various treatments for essential hyperhidrosis are available. The aim of this study is to present our experience with a simplified thoracoscopic sympathicolysis technique in this disorder, and to confront our results with data in the literature, 35 consecutive patients (11 male, 24 female, age 12-44 years) with essent...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1080/22953337.1996.11718517
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Turner syndrome (TS) is characterized by dysmorphism and body disproportion. TS women are also susceptible to a range of chronic disorders including arterial hypertension (AHT), osteoporosis, sensorineural hearing loss (SNHL), type 2 diabetes mellitus (DM2) and thyroid disease. The association between dysmor...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2019.1606761
更新日期:2020-08-01 00:00:00
abstract::A case of double neutrophilic population in a more or less symptomless patient is described. The diagnosis is made on one hand by the presence of 2 distinct neutrophil clusters on the PEROX display of the H* 1 hematological automate, on the other hand by cytochemical peroxidase staining which clearly confirms the exis...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1993.11718337
更新日期:1993-01-01 00:00:00
abstract::We retrospectively studied 29 cases of S.pyogenes bacteremia, treated from September 1985 through September 1993, in order to define the clinical pattern, predisposing factors and the outcome of S.pyogenes bacteremia in our region. The number of infections, the clinical picture and mortality rate of S.pyogenes bactere...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.1995.11718427
更新日期:1995-01-01 00:00:00
abstract::We performed a systematic survey of original papers published in The Lancet throughout the years 1945, 1946, 1970 and 1995. The Lancet was chosen due to a conservative layout through these years, and the year 1946 added to the analysis to ponder for any war-induced bias. The general layout and structure of the journal...
journal_title:Acta clinica Belgica
pub_type: 历史文章,杂志文章
doi:10.1179/acb.2004.011
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:We previously validated uHear™ to screen for hearing loss in older patients with cancer without a known hearing loss, as part of a comprehensive geriatric assessment (CGA). In view of low specificity, we tested a new modified uHear™ scoring system as described by Handzel. METHODS:Patients, aged ≥70 years, we...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1080/17843286.2017.1392070
更新日期:2018-04-01 00:00:00
abstract::Abnormal endothelial function plays a pivota role in the pathogenesis of diabetic complications. Due to lack of autoregulation of glucose transport in the presence of high extracellular glucose concentrations, intracellular hyperglycaemia induces a series of metabolic changes that ultimately lead to the genesis of bot...
journal_title:Acta clinica Belgica
pub_type: 杂志文章,评审
doi:10.1179/acb.2007.017
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:There has been an exponentially increasing interest in intraabdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) over the last decade, and different definitions have been suggested. Nevertheless, there has been an impetus from experts in the field to modify these definitions to reflect ou...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/acb.2007.62.s1.007
更新日期:2007-01-01 00:00:00
abstract::Papillary thyroid cancer is the most common form of thyroid malignancy in children and adult with frequent metastases to the cervical lymph nodes. We present a case of metastatic papillary thyroid cancer with remarkable imaging findings of consecutive metastatic calcified lymph nodes resembling a chain of rings. While...
journal_title:Acta clinica Belgica
pub_type: 杂志文章
doi:10.1179/2295333714Y.0000000084
更新日期:2015-04-01 00:00:00