当前位置： SCI文献检索 > JOURNAL OF CARDIAC FAILURE期刊下所有文献 > Prolonged electrocardiogram QRS duration independently predicts long-term mortality in patients hospitalized for heart failure with preserved systolic function.

Prolonged electrocardiogram QRS duration independently predicts long-term mortality in patients hospitalized for heart failure with preserved systolic function.

Abstract：

BACKGROUND:Prolonged electrocardiogram (ECG) QRS duration (>or=120 ms) is a risk factor for death in systolic heart failure, but its effects in heart failure with preserved systolic function (HFPSF) have not been extensively studied. We hypothesized that prolonged ECG QRS duration would independently predict long-term mortality in hospitalized HFPSF patients. METHODS AND RESULTS:We analyzed 872 HFPSF patients (defined as left ventricular ejection fraction >or=50%) admitted to Michigan community hospitals between 2002 and 2004 and followed for a median of 660 days. We used Cox proportional hazards models to assess mortality hazard for prolonged QRS duration (>or=120 ms) on the last available predischarge ECG, first on a univariable basis and then after multivariable adjustment for other known risk factors. Prolonged QRS duration increased univariable all-cause mortality (HR 1.71; 95% CI 1.33-2.19, P < .001) and after multivariable adjustment (HR 1.31; 95% CI 1.01-1.71, P=.04). The univariable effect size was larger in younger patients. In multivariable models, there was no significant interaction between prolonged QRS and age, hypertension, or coronary artery disease status. CONCLUSIONS:Prolonged QRS duration (>or=120 ms) on a predischarge ECG is an independent and consistent predictor of long-term mortality in hospitalized HFPSF patients.

journal_name

J Card Fail

journal_title

Journal of cardiac failure

authors

Hummel SL,Skorcz S,Koelling TM

doi

10.1016/j.cardfail.2009.02.002

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

553-60

issue

7

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(09)00059-1

journal_volume

15

pub_type

杂志文章,多中心研究

相关文献

JOURNAL OF CARDIAC FAILURE文献大全
  • Intravenous salt supplementation with low-dose furosemide for treatment of acute decompensated heart failure.

    abstract：BACKGROUND:Theoretically, salt supplementation should promote diuresis through increasing the glomerular filtration rate (GFR) during treatment of acute decompensated heart failure (ADHF) even with low-dose furosemide; however, there is little evidence to support this idea. METHODS AND RESULTS:This was a prospective, ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2014.01.012

    authors： Okuhara Y,Hirotani S,Naito Y,Nakabo A,Iwasaku T,Eguchi A,Morisawa D,Ando T,Sawada H,Manabe E,Masuyama T

    更新日期：2014-05-01 00:00:00

  • Identification of Heart Failure Events in Medicare Claims: The Atherosclerosis Risk in Communities (ARIC) Study.

    abstract：BACKGROUND:We examined the accuracy of Medicare heart failure (HF) diagnostic codes in the identification of acute decompensated (ADHF and chronic stable (CSHF) HF. METHODS AND RESULTS:Hospitalizations were identified from medical discharge records for Atherosclerosis Risk in Communities (ARIC) study participants with...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2015.07.013

    authors： Kucharska-Newton AM,Heiss G,Ni H,Stearns SC,Puccinelli-Ortega N,Wruck LM,Chambless L

    更新日期：2016-01-01 00:00:00

  • Association between prehospital delay and subsequent clinical course in patients with/hospitalized for heart failure.

    abstract：BACKGROUND:The clinical consequences of prehospital delay in heart failure (HF) patients are unknown. This study explores the relationship between prehospital delay of HF patients and length of hospital stay, plasma values of brain natriuretic peptides (BNP) as well as the association of delay with all-cause mortality,...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.cardfail.2011.12.007

    authors： Johansson P,van der Wal M,van Veldhuisen DJ,Jaarsma T

    更新日期：2012-03-01 00:00:00

  • Anabolics and cardiomyopathy in a bodybuilder: case report and literature review.

    abstract：BACKGROUND:Athletes use androgenic-anabolic steroids to increase strength and muscle mass. Several case reports suggest that it may lead to dilated cardiomyopathy. METHODS AND RESULTS:We report a case of a 41-year-old bodybuilder with severe systolic dysfunction and Class IV heart failure despite maximal medical thera...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2008.12.014

    authors： Ahlgrim C,Guglin M

    更新日期：2009-08-01 00:00:00

  • Impaired glucose tolerance and insulin resistance in heart failure: underrecognized and undertreated?

    abstract：BACKGROUND:A link between diabetes mellitus (DM) and heart failure (HF) has been well-recognized for more than a century. HF is also closely linked to abnormal glucose regulation (AGR) and insulin resistance (IR) in patients without DM and, similarly, these conditions commonly coexist. In epidemiological studies, each ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2010.05.027

    authors： Mamas MA,Deaton C,Rutter MK,Yuille M,Williams SG,Ray SG,New J,Gibson JM,Neyses L

    更新日期：2010-09-01 00:00:00

  • Association of Wolff-Parkinson-White With Left Ventricular Noncompaction Cardiomyopathy in Children.

    abstract：BACKGROUND:Wolff-Parkinson-White (WPW) has been associated with left ventricular noncompaction (LVNC) in children. Little is known about the prevalence of this association, clinical outcomes, and treatment options. METHODS:Retrospective review of subjects with LVNC. LVNC was defined by established criteria; those with...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2019.09.014

    authors： Howard TS,Valdes SO,Hope KD,Morris SA,Landstrom AP,Schneider AE,Miyake CY,Denfield SW,Pignatelli RH,Wang Y,Kim JJ

    更新日期：2019-12-01 00:00:00

  • The role of coenzyme Q10 in the pathophysiology and therapy of experimental congestive heart failure in the dog.

    abstract：BACKGROUND:Coenzyme Q10 (CoQ10) is essential for ATP generation and has antioxidant properties. Decreased CoQ10 levels have been reported in human heart failure (CHF), but it remains unclear if this is a conserved feature of CHF. The objective of the study was to determine if tachycardia-induced CHF in the dog is assoc...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2000.8839

    authors： Harker-Murray AK,Tajik AJ,Ishikura F,Meyer D,Burnett JC,Redfield MM

    更新日期：2000-09-01 00:00:00

  • Effect of intravenous immunoglobulin for fulminant myocarditis on in-hospital mortality: propensity score analyses.

    abstract：BACKGROUND:Fulminant myocarditis (FM) is a rare but life-threatening disease. Intravenous immunoglobulin (IVIG) is not recommended for acute or chronic myocarditis in Western nations owing to the lack of rigorous evidence, but it is widely used in other countries, including Japan. This nationwide retrospective cohort s...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2015.01.004

    authors： Isogai T,Yasunaga H,Matsui H,Tanaka H,Horiguchi H,Fushimi K

    更新日期：2015-05-01 00:00:00

  • Patterns of cardiac toxicity associated with irreversible proteasome inhibition in the treatment of multiple myeloma.

    abstract：:Carfilzomib is a novel irreversible proteasome inhibitor (PI) used with increasing frequency to treat patients with relapsed and/or refractory multiple myeloma (RRMM). This agent is an effective treatment for this challenging population, but proteasome inhibition has the potential of significant cardiac toxicity via t...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2014.11.008

    authors： Grandin EW,Ky B,Cornell RF,Carver J,Lenihan DJ

    更新日期：2015-02-01 00:00:00

  • Racial differences in treatment-seeking delays among heart failure patients.

    abstract：BACKGROUND:Treatment-seeking delays for heart failure (HF) symptoms are significantly high. However, earlier studies did not closely examine race as a characteristic that could potentially influence delay times. The purpose of this study was (1) to describe racial differences in treatment-seeking delays for HF symptoms...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2002.129234

    authors： Evangelista LS,Dracup K,Doering LV

    更新日期：2002-12-01 00:00:00

  • Risk Prediction Models for Incident Heart Failure: A Systematic Review of Methodology and Model Performance.

    abstract：BACKGROUND:Numerous models predicting the risk of incident heart failure (HF) have been developed; however, evidence of their methodological rigor and reporting remains unclear. This study critically appraises the methods underpinning incident HF risk prediction models. METHODS AND RESULTS:EMBASE and PubMed were searc...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2017.03.005

    authors： Sahle BW,Owen AJ,Chin KL,Reid CM

    更新日期：2017-09-01 00:00:00

  • Aldosterone antagonism improves endothelial-dependent vasorelaxation in heart failure via upregulation of endothelial nitric oxide synthase production.

    abstract：BACKGROUND:Altering the renin-angiotensin aldosterone system improve mortality in heart failure (HF) in part through an improvement in nitric oxide (NO)-mediated endothelial function. This study examined if spironolactone affects endothelial nitric oxide synthase (eNOS) and NO-mediated vasorelaxation in HF. METHODS AN...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2006.01.002

    authors： Thai HM,Do BQ,Tran TD,Gaballa MA,Goldman S

    更新日期：2006-04-01 00:00:00

  • Decoupling Between Diastolic Pulmonary Arterial Pressure and Pulmonary Arterial Wedge Pressure at Incremental Left Ventricular Assist Device (LVAD) Speeds Is Associated With Worse Prognosis After LVAD Implantation.

    abstract：BACKGROUND:Decoupling between diastolic pulmonary arterial pressure (dPAP) and pulmonary arterial wedge pressure (PAWP) is an index of pulmonary vasculature remodeling and provides prognostic information. Furthermore, decoupling may change during incremental left ventricular assist device (LVAD) speed changes. METHODS...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2018.08.003

    authors： Imamura T,Kim G,Raikhelkar J,Sarswat N,Kalantari S,Smith B,Rodgers D,Chung B,Nguyen A,Ota T,Song T,Juricek C,Jeevanandam V,Burkhoff D,Sayer G,Uriel N

    更新日期：2018-09-01 00:00:00

  • Polymorphisms of matrix metalloproteinases in systolic heart failure: role on disease susceptibility, phenotypic characteristics, and prognosis.

    abstract：BACKGROUND:The role of matrix metalloproteinases (MMPs) polymorphisms on heart failure (HF) susceptibility, phenotypic characteristics, and prognosis has been poorly explored. METHODS AND RESULTS:We studied 313 HF patients with left ventricular systolic dysfunction and 367 healthy control subjects. Genotyping of MMP-1...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2010.09.017

    authors： Velho FM,Cohen CR,Santos KG,Silvello D,Martinelli N,Biolo A,Clausell N,Rohde LE

    更新日期：2011-02-01 00:00:00

  • Decreased heart rate recovery after exercise in patients with congestive heart failure: effect of beta-blocker therapy.

    abstract：BACKGROUND:Decreased heart rate recovery (HRR) is a predictor of mortality in patients with coronary artery disease and preserved left ventricular function. We investigated the changes in HRR and assessed the impact of beta-blockade therapy on these parameters in patients with symptomatic congestive heart failure (CHF)...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1054/jcaf.2003.47

    authors： Racine N,Blanchet M,Ducharme A,Marquis J,Boucher JM,Juneau M,White M

    更新日期：2003-08-01 00:00:00

  • How does cardiac resynchronization therapy improve exercise capacity in chronic heart failure?

    abstract：BACKGROUND:Studies have shown that neither ejection fraction nor hemodynamic abnormalities during exercise in chronic heart failure (HF) correlate with symptoms of fatigue and exhaustion. The concept that exercise limitation in patients with chronic HF is due to abnormal hemodynamics during exercise has been revised to...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1016/j.cardfail.2005.03.002

    authors： Middlekauff HR

    更新日期：2005-09-01 00:00:00

  • Differences in education, knowledge, self-management activities, and health outcomes for patients with heart failure cared for under the chronic disease model: the improving chronic illness care evaluation.

    abstract：BACKGROUND:The objective of this study was to determine whether participation in a quality improvement (QI) collaborative for heart failure (HF) was associated with better interpersonal aspects of care and health outcomes. METHODS AND RESULTS:We conducted a cross-sectional telephone survey of patients in 6 organizatio...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2005.03.010

    authors： Baker DW,Asch SM,Keesey JW,Brown JA,Chan KS,Joyce G,Keeler EB

    更新日期：2005-08-01 00:00:00

  • Quality assurance and cardiopulmonary exercise testing in clinical trials.

    abstract：BACKGROUND:Peak oxygen uptake (VO2) measured during cardiopulmonary exercise testing (CPX) is often used as an outcome measure in clinical trials. The purposes of this study are (a) to report the outcomes of a quality assurance (QA) procedure instituted in multisite clinical trials by a CPX data core laboratory and (b)...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2008.01.001

    authors： Brawner CA,Ehrman JK,Aldred H,Schairer JR,Keteyian SJ

    更新日期：2008-05-01 00:00:00

  • The extracellular connections: the role of integrins in myocardial remodeling.

    abstract：BACKGROUND:Integrins are a large family of heterodimeric cell surface receptors that are present on all cells. These molecules link the extracellular matrix to the intracellular cytoskeleton and are multifunctional, playing roles in cell organization and differentiation, migration, alteration of gene expression, and ce...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1054/jcaf.2002.129263

    authors： Ross RS

    更新日期：2002-12-01 00:00:00

  • Utilization of trained volunteers decreases 30-day readmissions for heart failure.

    abstract：:Background: This study evaluated the effectiveness of using trained volunteer staff in reducing 30-day readmissions of congestive heart failure (CHF) patients.Methods: From June 2010 to December 2010, 137 patients (mean age 73 years) hospitalized for CHF were randomly assigned to either: an interventional arm (arm A) ...

    journal_title：Journal of cardiac failure

    pub_type： 更正并重新发布的文章,杂志文章,随机对照试验

    doi：

    authors： Sales VL,Ashraf MS,Lella LK,Huang J,Bhumireddy G,Lefkowitz L,Feinstein M,Kamal M,Caesar R,Cusick E,Norenberg J,Lee J,Brener S,Sacchi TJ,Heitner JF

    更新日期：2014-05-01 00:00:00

  • Natriuretic peptides in the treatment of heart failure.

    abstract：BACKGROUND:This study was designed to examine the hemodynamic, renal, and hormonal effects of infusion of A-type natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) in patients with congestive heart failure (CHF). METHODS AND RESULTS:We infused synthetic human ANP or BNP at a rate of 0.1 microgram/kg/ min i...

    journal_title：Journal of cardiac failure

    pub_type： 临床试验,杂志文章

    doi：10.1016/s1071-9164(96)80088-1

    authors： Yasue H,Yoshimura M

    更新日期：1996-12-01 00:00:00

  • Treatment of heart failure according to William Stokes: the enchanted mercury.

    abstract：BACKGROUND:It was not until 1919 that the diuretic properties of mercury were observed in patients with syphilis; in the same year the beneficial effects of mercurial diuretics were shown in a patient with severe rheumatic heart disease and anasarca. However, mercury had been used much earlier for the treatment of drop...

    journal_title：Journal of cardiac failure

    pub_type： 传,历史文章,杂志文章

    doi：10.1054/jcaf.2001.26564

    authors： Ventura HO,Mehra MR,Young JB

    更新日期：2001-09-01 00:00:00

  • Functional electrical stimulation is more effective in severe symptomatic heart failure patients and improves their adherence to rehabilitation programs.

    abstract：BACKGROUND:Functional electrical stimulation (FES) improves exercise capacity and quality of life in chronic heart failure (CHF) patients. However, there is no evidence regarding the effectiveness of this treatment modality according to the severity of CHF. This study compares the effectiveness of FES on exercise capac...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2009.10.023

    authors： Karavidas A,Parissis JT,Matzaraki V,Arapi S,Varounis C,Ikonomidis I,Grillias P,Paraskevaidis I,Pirgakis V,Filippatos G,Kremastinos DT

    更新日期：2010-03-01 00:00:00

  • Improvement of serum NT-ProBNP predicts improvement in cardiac function and favorable prognosis after cardiac resynchronization therapy for heart failure.

    abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) is now an established therapy for patients with advanced heart failure with electromechanical delay, although nonresponders have been observed. Because natriuretic peptides are relevant markers to reflect the severity of heart failure and filling pressure of cardiac ch...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2005.04.007

    authors： Yu CM,Fung JW,Zhang Q,Chan CK,Chan I,Chan YS,Kong SL,Sanderson JE,Lam CW

    更新日期：2005-06-01 00:00:00

  • Surgical ablation of atrial fibrillation in patients with congestive heart failure.

    abstract：BACKGROUND:Congestive heart failure (CHF) and atrial fibrillation (AF), both of which cause morbidity and mortality, are mutually promoting diseases. We aimed to evaluate surgical AF ablation in CHF. METHODS AND RESULTS:Among 212 patients (age 69 +/- 8.8 years, 87% with persistent AF) undergoing concomitant left atria...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2007.04.011

    authors： Grubitzsch H,Dushe S,Beholz S,Dohmen PM,Konertz W

    更新日期：2007-09-01 00:00:00

  • Prolonged electrical muscle stimulation exercise improves strength, peak VO2, and exercise capacity in patients with stable chronic heart failure.

    abstract：BACKGROUND:Exercise training can help patients with chronic heart failure but may be limited in its applicability due to age and other comorbidities. This investigation evaluated training responses to prolonged electrical muscle stimulation (EMS) in patients with stable chronic heart failure. METHODS AND RESULTS:In a ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.cardfail.2008.11.005

    authors： Banerjee P,Caulfield B,Crowe L,Clark AL

    更新日期：2009-05-01 00:00:00

  • The relationship between aldosterone, oxidative stress, and inflammation in chronic, stable human heart failure.

    abstract：BACKGROUND:Aldosterone antagonists reduce morbidity and mortality in patients with severe heart failure, but the mechanisms responsible are not fully understood. Observations in animal models suggest that elevated levels of aldosterone promote oxidative stress and inflammation in the myocardium. It is unknown if these ...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2005.08.005

    authors： Kotlyar E,Vita JA,Winter MR,Awtry EH,Siwik DA,Keaney JF Jr,Sawyer DB,Cupples LA,Colucci WS,Sam F

    更新日期：2006-03-01 00:00:00

  • The prevalence and pattern of complementary and alternative supplement use in individuals with chronic heart failure.

    abstract：BACKGROUND:There are few data on the prevalence and pattern of complementary and alternative medicine (CAM) supplement use among people with chronic heart failure (CHF). The aim of this survey was to characterize the prevalence, pattern, and reasons for use of CAM supplements among those with CHF. METHODS AND RESULTS:...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2005.06.427

    authors： Zick SM,Blume A,Aaronson KD

    更新日期：2005-10-01 00:00:00

  • Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction.

    abstract：BACKGROUND:Tissue kallikrein is a serine proteinase that generates the vasoactive kinin peptide, which produces vasodilatory, angiogenic, and antiapoptotic effects. In this study, we investigated the effect of a stable supply of kallikrein and kinin on ventricular remodeling and blood vessel growth in rats after myocar...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章

    doi：10.1016/j.cardfail.2007.04.009

    authors： Yao YY,Yin H,Shen B,Chao L,Chao J

    更新日期：2007-09-01 00:00:00

  • Muscle cell grafting for the treatment and prevention of heart failure.

    abstract：BACKGROUND:The review aims to highlight recent advances in cardiac and skeletal muscle cell grafting for myocardial infarct repair. RESULTS:Fetal and neonatal cardiomyocytes form new myocardium in normal or injured hearts, and this new myocardium differentiates toward an adult phenotype. Unfortunately, formation of ne...

    journal_title：Journal of cardiac failure

    pub_type： 杂志文章,评审

    doi：10.1054/jcaf.2002.129268

    authors： Murry CE,Whitney ML,Reinecke H

    更新日期：2002-12-01 00:00:00