Abstract:
:Glutamate is an excitatory neurotransmitter in the central and peripheral nervous systems of the vertebrate. The previous studies show the presence of mRNAs of AMPA-type glutamate receptors, GluR1 and GluR2, in the optic tectum of the pigeon, suggesting glutamatergic input from the retina. The present study examined localization of vesicular glutamate transporter 2 (VGLUT2) and GluR1 and GluR2 to confirm source of glutamatergic neurons in the pigeon retina by in situ hybridization histochemistry. VGLUT2 mRNA expressed in the inner nuclear layer and ganglion cells, while GluR1 and GluR2 mRNAs were observed in the inner nuclear layer, ganglion cells, and superficial layers of the optic tectum. The results suggest that photoreceptor cells, bipolar cells and ganglion cells are glutamatergic in the avian retina as in mammals.
journal_name
Exp Eye Resjournal_title
Experimental eye researchauthors
Islam MR,Atoji Ydoi
10.1016/j.exer.2009.03.024subject
Has Abstractpub_date
2009-09-01 00:00:00pages
439-43issue
3eissn
0014-4835issn
1096-0007pii
S0014-4835(09)00162-6journal_volume
89pub_type
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