当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Anti-inflammatory effects of ethanolic extract and alkamides-derived from Heliopsis longipes roots.

Anti-inflammatory effects of ethanolic extract and alkamides-derived from Heliopsis longipes roots.

Abstract：

ETHNOPHARMACOLOGICAL RELEVANCE:Heliopsis longipes (A. Gray) Blake (Asteraceae) is a broadly used species in the Mexican, Central and South American Traditional Medicine for its anaesthetic, analgesic, anti-inflammatory and anti-ulcerative properties. The ethanolic extract contains alkamides, mainly affinin (spilanthol). This family of compounds exerts an in vitro inhibitory action on the cyclooxygenase and lipoxygenase enzymes. AIM OF THE STUDY:The present study approaches the anti-inflammatory effect of the extract and its main bioactive component affinin and derived isobutyl-decanamide. MATERIALS AND METHODS:The anti-inflammatory effect was evaluated through the mouse ear oedema test by means of two irritating agents, arachidonic acid (AA) and phorbol myristate acetate (PMA). RESULTS:Heliopsis longipes, affinin and isobutyl-decanamide displayed a marked anti-inflammatory effect on the AA model with ED(50)=0.8, 1.2 and 0.9 mg/ear, respectively. Nimesulide (1 mg/ear) was used as a reference drug. In PMA model, the extract and two alkamides also showed a dose-dependent anti-inflammatory effect with ED(50)=2.0, 1.3 and 1.1 mg/ear, respectively. Indomethacin (3 mg/ear) was used as reference drug. CONCLUSIONS:These results could represent an important contribution to explain the anti-inflammatory ethnobotanical effects reported for Heliopsis longipes and other species containing affinin (spilanthol). For the first time the topical anti-inflammatory effects of Heliopsis longipes, affinin and isobutyl-decanamide were studied.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Hernández I,Márquez L,Martínez I,Dieguez R,Delporte C,Prieto S,Molina-Torres J,Garrido G

doi

10.1016/j.jep.2009.04.060

subject

Has Abstract

pub_date

2009-07-30 00:00:00

pages

649-52

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(09)00288-8

journal_volume

124

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • The hypoglucemic effect of Opuntia streptacantha studied in different animal experimental models.

    abstract：:Studies performed with Opuntia streptacantha sap in three different animal species using several experimental conditions are described. The Opuntia sap induced hypoglucemic effects when orally administered to intact animals under induced states of moderate increase of blood sugar. In normoglucemic and pancreatectomize...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(83)90019-3

    authors： Ibañez-Camacho R,Meckes-Lozoya M,Mellado-Campos V

    更新日期：1983-03-01 00:00:00

  • Ameliorative potential of standardized fruit extract of Pterodon pubescens Benth on neuropathic pain in mice: Evidence for the mechanisms of action.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The medicinal plant Pterodon pubescens Benth has been traditionally used for a long time to treat rheumatic diseases due to its anti-inflammatory and analgesic activities. The present study aims to evaluate the antinociceptive effect of ethanolic extract from P. pubescens fruits (EEPp) in...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.09.005

    authors： Nucci-Martins C,Martins DF,Nascimento LF,Venzke D,Oliveira AS,Frederico MJ,Silva FR,Brighente IM,Pizzolatti MG,Santos AR

    更新日期：2015-12-04 00:00:00

  • Gynura procumbens ethanol extract and its fractions inhibit macrophage derived foam cell formation.

    abstract：ETHNOPHARMACOLOGY RELEVANCE:Gynura procumbens (Lour.) Merr. displayed cardio-protective effect that may prevent atherogenesis. The primary underlying pathological process of cardiovascular disease is atherosclerosis. Atherosclerotic lesion composed of macrophages, T cells and other immune cells which incorporated with ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112410

    authors： Manogaran M,Vuanghao L,Mohamed R

    更新日期：2020-03-01 00:00:00

  • Green tea leaf extract improves lipid and glucose homeostasis in a fructose-fed insulin-resistant hamster model.

    abstract：:The present study evaluated the effect of green tea (Camellia sinensis L.) leaf extract on triglyceride and glucose homeostasis in a fructose-fed hypertriglyceridemic, insulin-resistant hamster model. There was a significant decrease in plasma triglyceride levels following supplementation of the green tea epigallocate...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.08.045

    authors： Li RW,Douglas TD,Maiyoh GK,Adeli K,Theriault AG

    更新日期：2006-03-08 00:00:00

  • The antibacterial properties of an Aztec wound remedy.

    abstract：:Wound treatment practices of the Aztecs are discussed. The use of concentrated maguey sap (Agave ssp.) was widely dispersed and has persisted in folk medicine. A possible reason may be that it is effective. Laboratory analysis of maguey syrup indicates that its utilization as a remedy by ancient and modern Mesoamerica...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(83)90051-x

    authors： Davidson JR,Ortiz de Montellano BR

    更新日期：1983-08-01 00:00:00

  • The inhibitory effect of gypenoside stereoisomers, gypenoside L and gypenoside LI, isolated from Gynostemma pentaphyllum on the growth of human lung cancer A549 cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Gypenosides are major constituents in Gynostemma pentaphyllum (Thunb.) Makino. Previous studies have shown that gypenosides isolated from G. pentaphyllum possess inhibitory effect on the growth of cancer cells, especially A549 cells, with structure-activity relationship (SAR). However, th...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.03.012

    authors： Xing SF,Liu LH,Zu ML,Ding XF,Cui WY,Chang T,Piao XL

    更新日期：2018-06-12 00:00:00

  • Effects and mechanisms of total glucosides of paeony on adjuvant arthritis in rats.

    abstract：:Total glucosides of paeony (TGP) is the major active constituent of Paeonia lactiflora Pall. The present study was carried out to investigate the effects of TGP on adjuvant arthritis (AA) of rat and its possible mechanisms. AA was induced by metatarsal footpad injection with complete Freund's adjuvant in male Sprague-...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2006.08.019

    authors： Xu HM,Wei W,Jia XY,Chang Y,Zhang L

    更新日期：2007-02-12 00:00:00

  • Lepidium meyenii (Maca) enhances the serum levels of luteinising hormone in female rats.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Lepidium meyenii (Maca) is traditionally employed in the Andean region for its supposed fertility benefits. This study investigated the effect of Maca on the serum pituitary hormone levels during the pro-oestrus phase. MATERIALS AND METHODS:Maca powder was made from the tubers of Lepidiu...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.11.058

    authors： Uchiyama F,Jikyo T,Takeda R,Ogata M

    更新日期：2014-02-03 00:00:00

  • Medicinal plants of the Popoluca, México: organoleptic properties as indigenous selection criteria.

    abstract：:The taste and smell of the environment are important to humans in everyday life and are of particular relevance for the selection of medicinal versus non-medicinal plant species. In a 16-months study with the Popoluca of southern Veracruz (Mexico), we focused on the indigenous selection criteria for medicinal plants. ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00078-8

    authors： Leonti M,Sticher O,Heinrich M

    更新日期：2002-08-01 00:00:00

  • Wenshen Zhuanggu formula mitigates breast cancer bone metastasis through the signaling crosstalk among the Jagged1/Notch, TGF-β and IL-6 signaling pathways.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Advanced breast cancer frequently metastasizes to the bone, resulting in patient morbidity and mortality. The interaction of tumor cells with osteoclasts and osteoblasts seriously affects the occurrence and development of bone metastasis in breast cancer. The signaling crosstalk among the...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.12.023

    authors： Wu C,Chen M,Sun Z,Ye Y,Han X,Qin Y,Liu S

    更新日期：2019-03-25 00:00:00

  • Sauropus androgynus L. Merr.-A phytochemical, pharmacological and toxicological review.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sauropus androgynus L. Merr is an underexploited perennial shrub traditionally used as a medicinal plant in South Asia and Southeast Asia. The plant is regarded as not just a green vegetable for diet, but as a traditional herb for certain aliments. For instance, it has traditionally been ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2020.112778

    authors： Zhang BD,Cheng JX,Zhang CF,Bai YD,Liu WY,Li W,Koike K,Akihisa T,Feng F,Zhang J

    更新日期：2020-07-15 00:00:00

  • Reconstruction of the inventory of materia medica used by members of the Jewish community of medieval Cairo according to prescriptions found in the Taylor-Schechter Genizah collection, Cambridge.

    abstract：:The Taylor-Schechter (T-S) collection at Cambridge University Library is the biggest of all Cairo Genizah collections in the world. The importance and the potential of research into the medical aspects of the Genizah documents were clear to researcher since the early 1960s. A few works have been published since, usual...

    journal_title：Journal of ethnopharmacology

    pub_type： 历史文章,杂志文章

    doi：10.1016/j.jep.2006.06.005

    authors： Lev E,Amar Z

    更新日期：2006-12-06 00:00:00

  • Preliminary phytochemical, pharmacological and antibacterial studies of the alkaloidal extracts of the leaves of Synclisia scabrida Miers.

    abstract：:Preliminary phytochemical investigation of the leaves of Synclisia scabrida indicated the presence of two alkaloids in the water extracts and five alkaloids in the ethanol extracts. The alkaloidal fraction obtained from the cold ethanol extract furnished on column-chromatography, a homogeneous amorphous solid which ha...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(86)90029-2

    authors： Sokomba E,Wambebe C,Chowdhury BK,Iriah J,Ogbeide ON,Orkor D

    更新日期：1986-11-01 00:00:00

  • Vasodilating and hypotensive effects of fangchinoline and tetrandrine on the rat aorta and the stroke-prone spontaneously hypertensive rat.

    abstract：:Comparative studies of the effects of tetrandrine (TET) and fangchinoline (FAN), two major components of the Radix of Stephannia tetrandrae, on vasodilations and on calcium movement in vascular smooth muscle, and studies of hypotensive effects on stroke-prone spontaneously hypertensive rats (SHRSP) were performed in t...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(97)00092-5

    authors： Kim HS,Zhang YH,Oh KW,Ahn HY

    更新日期：1997-10-01 00:00:00

  • Effects of deer velvet extract from Formosan sika deer on the embryonic development and anti-oxidative enzymes mRNA expression in mouse embryos.

    abstract：ETHNOPHARMACROLOGICAL RELEVANCE:The deer velvet or its extracts has been widely used in clinic. It has been used in promoting reproductive performances and treating of oxidation and aging process. The aim of this study is to investigate the effects of velvet extract from Formosan sika deer (Formosan sika deer; Cervus n...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.04.006

    authors： Cheng SL,Lai YL,Lee MC,Shen PC,Liu SS,Liu BT

    更新日期：2014-07-03 00:00:00

  • Effect of traditional Chinese medicine formula GeGen decoction on primary dysmenorrhea: A randomized controlled trial study.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:GeGen Decoction, a well-known Chinese herbal formula, is widely used in China and other Asian countries to treat gynecological diseases, including primary dysmenorrhea. Pharmacological studies have confirmed that GeGen Decoction is able to inhibit spasmodic contractions of the uterus in v...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113053

    authors： Chai C,Hong F,Yan Y,Yang L,Zong H,Wang C,Liu Z,Yu B

    更新日期：2020-10-28 00:00:00

  • Studies on the toxicity of gambogic acid in rats.

    abstract：AIM:To study the chronic toxicity of gambogic acid (GA), the major active ingredient of gamboges, a brownish to orange resin extracted from the Garcinia hanburyi (family Guttiferae) in Southeast Asia, using Sprague-Dawley rat as an animal model and provide further theoretical support for clinical applications of this p...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.02.027

    authors： Qi Q,You Q,Gu H,Zhao L,Liu W,Lu N,Guo Q

    更新日期：2008-05-22 00:00:00

  • Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.

    abstract：:A total of 18 organosulfur compounds originating from Petiveria alliacea L. roots have been tested for their antibacterial and antifungal activities. These represent compounds occurring in fresh homogenates as well as those present in various macerates, extracts and other preparations made from Petiveria alliacea. Of ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.08.072

    authors： Kim S,Kubec R,Musah RA

    更新日期：2006-03-08 00:00:00

  • Dehydropachymic acid decreases bafilomycin A1 induced β-Amyloid accumulation in PC12 cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Fuling, the sclerotium of Poria cocos, was frequently used in traditional Chinese medicine (TCM) formulae for Alzheimer's disease (AD) intervention over the past 10 centuries. And its extracts exhibited significant effects in both cellular and animal models of AD in previous studies. Howe...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.01.007

    authors： Yu M,Xu X,Jiang N,Wei W,Li F,He L,Luo X

    更新日期：2017-02-23 00:00:00

  • An ethnopharmacological survey of the traditional medicine utilized in the community of Porvenir, Bajo Paraguá Indian Reservation, Bolivia.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Porvenir is a semi-isolated Indian community in the Bajo Paraguá Indian Reservation in Bolivian Amazon, one of the two communities of people from the Guarasug'we indigenous nation now close to extinction. The aim of our study was the collection of data on the traditional medicine utilized...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.12.029

    authors： Hajdu Z,Hohmann J

    更新日期：2012-02-15 00:00:00

  • Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through targeting IL-6-induced JAK2/STAT3 pathway in human colorectal cancer cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Panax ginseng is one of the most well-known medicinal herbs in Korea and China, which has been used for treatment and prevention of cancer, obesity, diabetes, and cardiovascular diseases. Ginsenosides are the major components of P. ginseng, having a wide range of pharmacological activitie...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.08.039

    authors： Han S,Jeong AJ,Yang H,Bin Kang K,Lee H,Yi EH,Kim BH,Cho CH,Chung JW,Sung SH,Ye SK

    更新日期：2016-12-24 00:00:00

  • Antineoplastic agents 338. The cancer cell growth inhibitory. Constituents of Terminalia arjuna (Combretaceae).

    abstract：:By means of bioassay-guided separation methods, the cancer cell growth inhibitory constituents residing in the bark, stem and leaves of the Mauritius medicinal plant Terminalia arjuna (Combretaceae) were examined. The cancer cell line active components were found to be gallic acid, ethyl gallate, and the flavone luteo...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/S0378-8741(96)01421-3

    authors： Pettit GR,Hoard MS,Doubek DL,Schmidt JM,Pettit RK,Tackett LP,Chapuis JC

    更新日期：1996-08-01 00:00:00

  • Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update.

    abstract：:After a short description of the uses of pineapple as folk medicine by the natives of the tropics, the more important new pharmaceutical applications of bromelain, reported between 1975 and 1978, are presented. Although the exact chemical structure of all active components of bromelain is not fully determined, this su...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/0378-8741(88)90127-4

    authors： Taussig SJ,Batkin S

    更新日期：1988-02-01 00:00:00

  • Evaluation of the impact of Polygonum capitatum, a traditional Chinese herbal medicine, on rat hepatic cytochrome P450 enzymes by using a cocktail of probe drugs.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Polygonum capitatum is a well-known Miao medicinal plant that has been used for many years for its unique therapeutic effects on various urological disorders, including urinary calculus and urinary tract infections. To investigate the effect of Polygonum capitatum on cytochrome P450 (CYP)...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.10.031

    authors： Zheng L,Lu Y,Cao X,Huang Y,Liu Y,Tang L,Liao SG,Wang AM,Li YJ,Lan YY,Wang YL

    更新日期：2014-12-02 00:00:00

  • Antimicrobial activity of the methanolic extract, fractions and four flavonoids from the twigs of Dorstenia angusticornis Engl. (Moraceae).

    abstract：:The methanolic extract (DAT), fractions (FRS) and four flavonoids, namely Gancaonin Q (1), Stipulin (2), Angusticornin B (3) and Bartericin A (4), isolated from the twigs of Dorstenia angusticornis (Moraceae), were tested for their in vitro antimicrobial activity. A total of 22 microbial cultures belonging to three Ca...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.03.008

    authors： Kuete V,Simo IK,Ngameni B,Bigoga JD,Watchueng J,Kapguep RN,Etoa FX,Tchaleu BN,Beng VP

    更新日期：2007-06-13 00:00:00

  • Investigation of Lepechinia graveolens for its antioxidant activity and phenolic composition.

    abstract：:A bioguided separation of Lepechinia graveolens (Reg.) Epling. (Lamiaceae) for antioxidant activity was carried out. The ethyl acetate fraction (EAF) from the methanolic extract was chromatographed on Sephadex LH-20 affording five active fractions. The radical scavenging activity of each fraction, as well as that of t...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.05.017

    authors： Parejo I,Caprai E,Bastida J,Viladomat F,Jáuregui O,Codina C

    更新日期：2004-09-01 00:00:00

  • The anti-diabetic activity of licorice, a widely used Chinese herb.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:A great deal of valuable experience has been accumulated in the traditional Chinese medicine (TCM) system for the treatment of "Xiaoke" disease which is known as diabetes mellitus now. As the most-commonly used Chinese herb, licorice has been used in TCM for more than two thousand years. ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2020.113216

    authors： Yang L,Jiang Y,Zhang Z,Hou J,Tian S,Liu Y

    更新日期：2020-12-05 00:00:00

  • Chemical characterization and evaluation of gastric antiulcer properties of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Virola elongata is a tree species belonging to the Myristicaceae family, distributed in the North and Midwest regions of Brazil, in the phytogeographic domain of the Amazon. The aqueous infusion or the hydroethanolic macerate of the stem bark of V. elongata are used in Brazilian and Ecuad...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.11.011

    authors： Almeida GVB,Arunachalam K,Balogun SO,Pavan E,Ascêncio SD,Soares IM,Zanatta AC,Vilegas W,Macho A,Oliveira Martins DT

    更新日期：2019-03-01 00:00:00

  • Baitouweng decoction alleviates dextran sulfate sodium-induced ulcerative colitis by regulating intestinal microbiota and the IL-6/STAT3 signaling pathway.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Baitouweng (BTW) decoction, a Chinese traditional medicine prescription, has been used to treat ulcerative colitis (UC) over hundreds of years. In this study, we investigated the anti-inflammatory effects of BTW and intestinal flora of dextran sulfate sodium (DSS)-induced UC mice, and we ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113357

    authors： Xuan-Qing CHEN,Xiang-Yu LV,Shi-Jia LIU

    更新日期：2021-01-30 00:00:00

  • Hypolipidemic effect of different extracts of Clerodendron colebrookianum Walp in normal and high-fat diet fed rats.

    abstract：:Clerodendron colebrookianum Walp (family, Verbenaceae) has been used as a home remedy by the Mizo people of north eastern (NE) region of India in their folklore medicine as a cardioprotective (mainly against high blood pressure) agent. The scientific basis for their use has yet to be established. Therefore, in this in...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2003.09.022

    authors： Devi R,Sharma DK

    更新日期：2004-01-01 00:00:00