Antineoplastic agents 338. The cancer cell growth inhibitory. Constituents of Terminalia arjuna (Combretaceae).

Abstract:

:By means of bioassay-guided separation methods, the cancer cell growth inhibitory constituents residing in the bark, stem and leaves of the Mauritius medicinal plant Terminalia arjuna (Combretaceae) were examined. The cancer cell line active components were found to be gallic acid, ethyl gallate, and the flavone luteolin. Only gallic acid was previously known to occur in this plant. Luteolin has a well established record of inhibiting various cancer cell lines and may account for most of the rationale underlying the use of T. arjuna in traditional cancer treatments. Luteolin was also found to exhibit specific activity against the pathogenic bacterium Neisseria gonorrhoeae.

journal_name

J Ethnopharmacol

authors

Pettit GR,Hoard MS,Doubek DL,Schmidt JM,Pettit RK,Tackett LP,Chapuis JC

doi

10.1016/S0378-8741(96)01421-3

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

57-63

issue

2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(96)01421-3

journal_volume

53

pub_type

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