Abstract:
BACKGROUND:Superficial soft tissue sarcomas (sSTS) are an important and frequent subtype of soft tissue sarcoma (STS). A wider knowledge of this tumor type may lead to better strategies in tumor therapy. METHODS:An institutional review was performed on all patients with primary sSTS of the extremities and trunk operated on between 1990 and 2003. RESULTS:The medical records of 108 patients with sSTS were analyzed. The local recurrence rate was 11% after a median of 25 (mean 42) months. Metastases occurred in 21 patients (19%), and 79 patients lived without evidence of disease after a mean follow-up of 112 +/- 42 months. Mean survival time was 89 months at a cumulative 5-year survival rate of 85%. R0 resection significantly enhanced cumulative survival (p = .001), as did patient age < 60 years (p = .002), tumor grading G1 and G2 compared to G3 (p = .004), absence of positive lymph nodes (p = .018), and no occurrence of metastases (p = .001). Tumor size < or = 5 cm reduced the local recurrence rate significantly (p = .044). Significant multivariate risk factors for metastases were age > or = 60 years (p = .016) and tumor grade G3 (p = .021). CONCLUSIONS:Patients with sSTS who are > or = 60 years of age or who have G3 tumors have a high risk of distant metastases. Patients with T2 tumors have an elevated risk for local recurrence. Certainly all patients with sSTS should be in a tight after-care program to allow early diagnosis of local recurrence or distant metastases. Age < 60 years, tumor grade G1/2, no positive regional lymph nodes (N0), and a R0 resection are significant prognostic factors for survival.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lachenmayer A,Yang Q,Eisenberger CF,Boelke E,Poremba C,Heinecke A,Ohmann C,Knoefel WT,Peiper Mdoi
10.1007/s00268-009-0051-1subject
Has Abstractpub_date
2009-08-01 00:00:00pages
1641-9issue
8eissn
0364-2313issn
1432-2323journal_volume
33pub_type
杂志文章abstract::Outside Japan portosystemic shunts have been favored as the surgical procedure of choice for the management of portal hypertension of noncirrhotic etiology. Devascularization procedures have resulted in high rebleed rates probably owing to a limited extent of devascularization. We performed this study to assess the ef...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900641
更新日期:1999-11-01 00:00:00
abstract::The aim of this study was to investigate the epidemiologic characteristics and changing patterns of gallstone disease in Korea over a recent 20-year period. A total of 4020 gallstone patients who had undergone surgery at Seoul National University Hospital during 1981-2000 were analyzed according to periods: period I (...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-6879-x
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Acute appendicitis is the most common reason for abdominal surgery in young adults and children. Open appendectomy is still the treatment often chosen because it is simple, safe, and effective. Our aim was to study whether cosmetic results of appendectomy wounds are better after using continuous absorbable i...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-013-2396-8
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Our laboratory has previously shown that the levels of secreted prostaglandin E(2) (PGE(2)), Thromboxane B(2) (TxB(2)), and interleukin-6 (IL-6) by aortic explant cultures were high in patients with ruptured abdominal aortic aneurysm (AAA). In the present study, we sought to examine the secretory levels of t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9279-9
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Parastomal hernia (PH) is a frequent complication after end-colostomy formation. PH may negatively influence the quality of life in end-colostomy patients. Our study investigates the quality of life and body image (BI) in patients with an end-colostomy. METHODS:We conducted a cross-sectional study of end-...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3107-4
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Perioperative blood transfusion has been shown to be associated with poor outcome in various types of malignancy. However, the relationship between the amount of blood loss and specific types of cancer recurrence has not been documented. METHODS:We retrospectively examined the amount of intraoperative blood...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9979-4
更新日期:2009-06-01 00:00:00
abstract::It is a fundamental clinical observation that wounds do not heal in tissue that does not bleed, and they almost always heal in tissue that bleeds extensively. Continuous supply of oxygen to the tissue through microcirculation is vital for the healing process and for resistance to infection. Evaluation of tissue perfus...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-003-7398-5
更新日期:2004-03-01 00:00:00
abstract::Despite careful selection of cirrhotic patients with hepatocellular carcinoma (HCC), liver resection remains associated with a greater risk than in patients without underlying liver disease. In this study we assessed by multivariate analysis parameters associated with in-hospital mortality and morbidity in a selected ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/pl00012259
更新日期:1997-05-01 00:00:00
abstract::Technetium 99m ((99m)Tc)-methoxyisobutylisonitrile (MIBI) scintigraphy has been reported to be a useful method for visualizing the parathyroid glands for the diagnosis of hyperparathyroidism. Some drug metabolism transporters, such as p-glycoprotein (P-GP) or multidrug resistance-associated protein (MRP), are believed...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0177-2
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Parathyroid glands can mimic thyroid follicular lesions on fine-needle aspiration (FNA) cytology and can lead to unnecessary or incorrect surgery. Newer molecular panel tests using next-generation sequencing (NGS) include analysis of cell type-specific gene expression profiles such as parathyroid. The study ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4548-3
更新日期:2018-09-01 00:00:00
abstract::It is difficult to evaluate precisely the effects of one individual on an entire discipline such as surgery. Indeed, it is impossible to do so when such a discipline spans so vast a country as the United States of America. Nevertheless, as a mountain peak can be seen from afar, so may one perceive the influence of man...
journal_title:World journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1007/s002689900357
更新日期:1998-01-01 00:00:00
abstract::This study aimed to investigate the effects and timing of local anesthesia during laparoscopic surgery in terms of postoperative pain, nausea, and the need for opioids and antiemetics. This prospective study was carried out on 142 patients who underwent laparoscopic cholecystectomy. Peroperative local anesthesia was n...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7350-3
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Self-expanding metallic stents (SEMS) have been used as a bridge to surgery in patients with obstruction by colorectal cancer, but the oncologic safety of this technique has not yet been established. The aim of the present study was to compare the outcomes of bridge to surgery after SEMS insertion and nonobs...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0007-5
更新日期:2009-06-01 00:00:00
abstract::Squamous cell carcinoma of the anus (SCCA) is a rare disease in the average population but is an increasing concern among immunocompromised individuals, such as the HIV-seropositive. Coinfection with human papillomavirus (HPV) in this population is common. HPV infection is difficult to clear with a compromised immune ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-008-9835-y
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Abdominal packing (AP) in damage-control laparotomy (DCL) is a lifesaving technique that controls coagulopathic hemorrhage in severely injured trauma patients. However, the impact of the duration of AP on the incidence of re-bleeding and on intra-abdominal infections in penetrating abdominal trauma is not cl...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1745-3
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Small bowel obstruction (SBO) is characterized by a high rate of recurrence. In the present study, we aimed to compare the outcomes of patients managed either by conservative treatment or surgical operation for an episode of SBO. METHODS:The outcomes of all patients hospitalized at a single center for acute...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2733-6
更新日期:2014-12-01 00:00:00
abstract::Over the past three decades Canada has developed an exemplary system of universal health care. However, current financial constraints threaten to undermine the very foundation of the system that represents Canada's respect for social justice. The first of these two articles (Part 1) discusses the unique characteristic...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00298897
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:The reported high incidence of 30-60% postoperative pain after an elective day surgical orchidopexy is undesirable. We evaluated the efficacy of our analgesic regimen for unilateral orchidopexy in preschool children performed as a day surgical procedure. METHODS:Between January 2004 and December 2006, 247 c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9847-7
更新日期:2009-03-01 00:00:00
abstract::The major goal of wound healing biology is to determine how a wound can be induced to repair damaged tissue faster and more efficiently. Enhancement of dermal and epidermal regeneration is an extremely important goal for the treatment of many different types of wounds. Exogenous application of growth factors to the wo...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-004-2062-2
更新日期:2005-01-01 00:00:00
abstract::The effect of a treatment versus controls may be expressed in relative or absolute terms. For rational decision-making, absolute measures are more meaningful. The number needed to treat, the reciprocal of the absolute risk reduction, is a powerful estimate of the effect of a treatment. It is particularly useful becaus...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7916-8
更新日期:2005-05-01 00:00:00
abstract::A wide range of clinical symptoms and signs are observed with venous thrombosis. Nonetheless, clinical diagnosis has been found to be unreliable and accurate diagnostic methods must be used before potent therapy such as anticoagulation is instituted, since the complications of treatment themselves can be life-threaten...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01658825
更新日期:1990-09-01 00:00:00
abstract::Despite a slow decline in the incidence of gastric cancer over the last 90 years, we can still expect to see over 100,000 patients die of this disease each decade in England and Wales. The 5-year survival rate has not improved during this century, which is largely due to the stage at diagnosis being unchanged. There a...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00294709
更新日期:1995-07-01 00:00:00
abstract::This study assessed the results of surgical treatment for Graves' disease in our hospital and examined the relationship between the values of thyroid stimulating hormone (TSH) receptor antibodies and postoperative thyroid function. From 1983 to 1988, subtotal thyroidectomy was performed in 313 patients with Graves' di...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067345
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:There are few established metrics to define surgical capacity in resource-limited settings. Previous work hypothesizes that the relative frequency of cesarean sections (CS) at a hospital, expressed as a proportion of total operative procedures (%CS), may serve as a proxy measure of surgical capacity. We atte...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1629-6
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Enhanced recovery after surgery (ERAS(®)) pathways have reduced morbidity and length of hospital stay (LOS) in orthopedics, bariatric, and colorectal surgery. New perioperative care protocols have been tested in patients undergoing pancreaticoduodenectomy (PD), with controversial results on morbidity. Incomp...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2653-5
更新日期:2014-11-01 00:00:00
abstract::Four cases of H-type tracheoesophageal fistula are reported. The patients all had chronic aspiration from the esophagus. Although serious symptoms were present in all, definitive diagnoses were not made until the patients had reached 1, 6, 12, and 50 years of age, because ordinary radiologic methods failed to establis...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01654780
更新日期:1979-09-20 00:00:00
abstract::Those benign breast disorders that are amenable to improvement by aesthetic surgery are discussed from the points of view of indications, techniques, and results. ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01658430
更新日期:1989-11-01 00:00:00
abstract::The development of microsurgical techniques has supplied plastic surgery with a new chance to transfer tissue to nearly any recipient site of the body. Classical methods still have their value but also their limits in many circumstances. Free tissue transfer has proved its advantages, especially in covering defects in...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01670525
更新日期:1990-11-01 00:00:00
abstract::It is a fact that without ideas there is nothing. Without ideas and without innovations there is nothing to test. An interesting, often asked question is: How are ideas, innovations born? It is surely correct that people giving birth to ideas have special characteristics. These creative people are different but still ...
journal_title:World journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1007/s002689900577
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:This study aims to determine the prevalence and predictive factors for recurrence after sentinel lymph node biopsy (SLNB) and for sentinel lymph node positivity by SLNB in our population. METHODS:We followed up all SLNBs performed between 2002 and 2010 and analyzed data by R (version2.10.1), considering p <...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1420-0
更新日期:2012-04-01 00:00:00