[Regenerative potential of human adult precursor cells: cell therapy--an option for treating cartilage defects?].

abstract：:An attempt is made to compile the pharmacological data on the leading non-steroidal anti-inflammatory drugs. They concern the pharmacodynamics, the pharmacokinetics and the unwanted effects of these compounds. From these data a few suggestions for rational use are made: Ibuprofen and diclofenac present as drugs with s...

journal_title：Zeitschrift fur Rheumatologie

authors： Brune K

更新日期：1987-01-01 00:00:00

abstract：:ECG from 200 patients with radiologically and clinically definite rheumatoid arthritis were compared with those from a healthy group with the same age and sex distribution. The frequency of pathological changes of the ECG was found to be the same in both groups. Therefore doubt remains whether the pathological changes...

journal_title：Zeitschrift fur Rheumatologie

authors： Droste U,Zimmermann H

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVE:The aim in this study was to determine whether solute carrier family 22, member 4 (SLC22A4), and runt-related transcription factor 1 (RUNX1) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA) in populations of different ethnicities. METHODS:We conducted a literature search using th...

journal_title：Zeitschrift fur Rheumatologie

authors： Lee YH,Bae SC,Kim JH,Seo YH,Choi SJ,Ji JD,Song GG

更新日期：2015-05-01 00:00:00

abstract：:Cartilage destruction in arthritis and osteoarthritis is linked to aberrant cytokine and growth factor expression in the affected tissues. It becomes clear that the balance of protective and destructive cytokines is more important for the net destruction than the absolute levels of destructive mediators. IL-1 is a key...

journal_title：Zeitschrift fur Rheumatologie

authors： van den Berg WB

更新日期：1999-06-01 00:00:00

abstract：:To study the hormonal perturbations in FMS patients we injected sixteen FMS patients and seventeen controls a cocktail of the hypothalamic releasing hormones: Corticotropin-releasing hormone (CRH), Thyrotropin-releasing hormone (TRH), Growth hormone-releasing hormone (GHRH), and Luteinizing hormone-releasing hormone (...

journal_title：Zeitschrift fur Rheumatologie

authors： Riedel W,Layka H,Neeck G

更新日期：1998-01-01 00:00:00

abstract：:This article gives a comprehensive overview of diffuse interstitial lung diseases especially those associated with connective tissue diseases. Interstitial lung diseases (ILD) represent a heterogeneous group of diseases of very different and partially unknown etiologies. Therefore, an exact classification of the ILD i...

journal_title：Zeitschrift fur Rheumatologie

authors： Koller HK,Burghuber OC

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Leukotrienes and prostaglandines are important mediators of inflammation. While prostaglandine synthesis can be influenced by NSAIDs therapeutical approaches to the 5-lipoxygenase pathway are rare. Resinous extracts of Boswellia serrata (H15, indish incense), known from traditional ayurvedic medicine, decrea...

journal_title：Zeitschrift fur Rheumatologie

authors： Sander O,Herborn G,Rau R

更新日期：1998-02-01 00:00:00

abstract：:Diagnosis and management of the rare disease systemic sclerosis (scleroderma) is a challenge for the physician, not least due to the possible multitude of organ systems involved. The medico-legal assessment is important for the patient claiming insurance benefits or applying for early retirement due to scleroderma. Bo...

journal_title：Zeitschrift fur Rheumatologie

authors： Graninger M

更新日期：2007-10-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a mainstay in musculoskeletal imaging. The term"bone marrow edema" is frequently used for describing the radiological findings, especially with respect to rheumatic diseases. The referring physician should be aware that this term has a purely descriptive character and the pathophysi...

journal_title：Zeitschrift fur Rheumatologie

authors： Hamer OW,Kriegsmann J

更新日期：2012-01-01 00:00:00

abstract：:In a twenty-nine year old female patient with progressive systemic sclerosis (scleroderma) (PSS) and an impressing involvement of the intestine (disturbance of the oesophageal motility, pseudo-obstruction, malabsorption) a spontaneous, asymptomatic pneumoperitoneum is observed. Perforation or pneumatosis cystoides int...

journal_title：Zeitschrift fur Rheumatologie

authors： Lang B,Meske S,Billmann P,Vaith P,Peter HH

更新日期：1986-03-01 00:00:00

abstract：:Still's disease covers a range of disorders from systemic juvenile idiopathic arthritis (SJIA) up to adult onset Still's disease (AOSD). The overlapping clinical features suggest that SJIA and AOSD are different manifestations of a phenotypic continuum in different age stages. Still's disease is clinically characteriz...

journal_title：Zeitschrift fur Rheumatologie

authors： Föll D,Wittkowski H,Hinze C

更新日期：2020-09-01 00:00:00

abstract：:Temporomandibular joint affections in rheumatic disease are described. They were seen in inflamed joint diseases, mostly in rheumatoid arthritis, and less so in juvenile rheumatoid arthritis, psoriatic arthritis, Reiter's syndrome, ankylosing spondylitis, and collagen vascular disease. In osteoarthrosis, the temporoma...

journal_title：Zeitschrift fur Rheumatologie

authors： Wörth WD,Keller B,Graber G,Müller W

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis is found in approximately 2 % of the total population in Europe and the peak incidence of the disease is during the fourth and fifth decades of life. In approximately 15 % the first symptoms of the disease occur at the level of the foot and ankle. If the early stage-dependent therapy wit...

journal_title：Zeitschrift fur Rheumatologie

authors： Thomas M,Jordan M

更新日期：2014-11-01 00:00:00

abstract：:The revised S2 guidelines for treatment of giant cell arteritis have recently been published. Glucocorticosteroids remain the standard first line treatment. For severe or relapsing courses of the disease, the IL‑6 antagonist tocilizumab, a potent antibody, is now available as a therapeutic option; however, how long th...

journal_title：Zeitschrift fur Rheumatologie

authors： Henes J

更新日期：2020-12-22 00:00:00

abstract：:Many rheumatological diseases are either caused by specific known proteins, such as antibodies or mediated by a plethora of cytokines. Both the unspecific immunosuppressive therapy and the specific action of biologics usually require time to be effective; therefore, extracorporeal forms of treatment are increasingly b...

journal_title：Zeitschrift fur Rheumatologie

authors： Boser M,Kielstein JT

更新日期：2016-12-01 00:00:00

abstract：:Mainly due to the general demographic changes and decreasing mortality in rheumatic diseases based on therapeutic progress, the proportion of older patients treated by rheumatologists is growing. Drug treatment in the elderly, however, harbors certain risks including age-specific pharmacokinetic features and high rate...

journal_title：Zeitschrift fur Rheumatologie

authors： Krüger K,Strangfeld A,Kneitz C

更新日期：2014-04-01 00:00:00

abstract：:The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synoviti...

journal_title：Zeitschrift fur Rheumatologie

authors： Krenn V,Perino G,Rüther W,Krenn VT,Huber M,Hügle T,Najm A,Müller S,Boettner F,Pessler F,Waldstein W,Kriegsmann J,Häupl T,Wienert S,Krukemeyer MG,Sesselmann S,Tikhilov R,Morawietz L

更新日期：2017-08-01 00:00:00

abstract：:A 28-year-old female patient had load-dependent pain of the left knee. MRI showed an osteochondral defect of the medial condyle based on extensive osteonecrosis of the femoral and tibial bone. An association with a prior steroid treatment after cervical injury is most likely. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Steinhagen J,Rüther W

更新日期：2004-06-01 00:00:00

abstract：:We investigated the relationships between prolactin (PRL) levels and antibody occurrence in systemic lupus erythematosus (SLE). No significant association between PRL levels and the majority of the autoantibodies studied (anti-U1 RNP, anti-rRNP, anti-Sm, anti-dsDNA, anti-DNP, auto-LCA, anti-EACA) could be confirmed (P...

journal_title：Zeitschrift fur Rheumatologie

authors： Kozáková D,Rovenský J,Cebecauer L,Bosák V,Jahnová E,Vigas M

更新日期：2000-01-01 00:00:00

abstract：:The antidesoxyribonuclease B reaction shows in persons of all classes of age examined a similar distribution of titres as the antistreptolysin reaction. The anti DNase B titres however are mostly lower than the titres of the antistreptolysin reaction, except in the group of children, 6 to 17 years of age, suffering fr...

journal_title：Zeitschrift fur Rheumatologie

authors： Otto R,Richter M,Scholz E,Neumann G

更新日期：1981-01-01 00:00:00

abstract：:Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...

journal_title：Zeitschrift fur Rheumatologie

authors： Valesová M,Trnavský K

更新日期：1990-07-01 00:00:00

abstract：:The painter Max Slevogt (1868-1932), together with Lovis Corinth and Max Liebermann, was one of the most important representatives of German impressionism. Slevogt, a gourmet who appreciated fine food and good wines, suffered from acute recurrent gouty arthritis starting at the age of 27 years. His medical history is ...

journal_title：Zeitschrift fur Rheumatologie

authors： Zeidler H

更新日期：2020-06-01 00:00:00

abstract：:Facing increasing health-related costs and limited health care resources, the assessment of cost effectiveness (CE) of medical procedures is also gaining considerable importance in the field of rheumatology. Since high annual therapy costs of 17,000-21,000 Euro are related to the employment of TNF-alpha blocking agent...

journal_title：Zeitschrift fur Rheumatologie

authors： Merkesdal S,Ruof J

更新日期：2002-01-01 00:00:00

abstract：:After approval of TNF and interleukin-1 inhibiting agents for treatment of refractory rheumathoid arthritis, new agents inhibiting interleukin-6 and costimulatory pathways are entering clinical phase I and II trials. Blockade of costimulation by using a CTLA4 immunoglobulin fusion protein (CTLA4Ig), which inhibits the...

journal_title：Zeitschrift fur Rheumatologie

authors： Perniok A,Rubbert-Roth A

更新日期：2003-10-01 00:00:00

abstract：:We report on a 39-year-old male patient suffering from seropositive rheumatoid arthritis who developed severe colitis during oral gold (Auranofin) therapy. So far, two further cases of colitis during oral, and 28 cases of enterocolitis during parenteral chrysotherapy have been described. The pathomechanism has not bee...

journal_title：Zeitschrift fur Rheumatologie

authors： Bross-Bach U,Saal JG,Hartmann F,Müller CA,Waller HD

更新日期：1987-07-01 00:00:00

abstract：:NSAIDs, including acetylsalicylic acid, are frequently classified as peripherally-acting analgesics. This is based on the fact that these substances, among other effects, inhibit the biosynthesis of prostaglandines. A few solid arguments, however, stand against an exclusively peripheral mode of the analgesic action of...

journal_title：Zeitschrift fur Rheumatologie

authors： Jurna I

更新日期：1991-01-01 00:00:00

abstract：:This study documents prospectively the Knee Society knee- and function score of 28 patients with rheumatoid arthritis with 34 PFC unconstrained total knee arthroplasties from preoperative values on at yearly intervals. The average follow-up period was 3.4 years (range 2-5.5 y). At last follow-up over 80% of the knees ...

journal_title：Zeitschrift fur Rheumatologie

authors： König A,Janssen E,Scheidler M,Gohlke F

更新日期：1997-07-01 00:00:00

abstract：:Eighteen patients suffering from chronic rheumatoid arthritis were selected for the present study. Plasma levels of stress hormones like catecholamines and cortisol were found to be elevated. At the same time reduction in percentage of E-rosette forming lymphocytes and an elevation in levels of major serum immunoglobu...

journal_title：Zeitschrift fur Rheumatologie

authors： Kumar R,Singh LM,Vaidya MP

更新日期：1981-05-01 00:00:00

abstract：AIM:To explore the circadian rhythm of serum interleukin (IL)-6 in collagen-induced arthritis (CIA) rats and compare the safety and effectiveness of methotrexate (MTX) administered traditionally and via chronotherapy. METHODS:CIA rat models were immunized with bovine type II collagen. Serum IL-6 levels in normal and C...

journal_title：Zeitschrift fur Rheumatologie

authors： Wang X,Yan X,Wang F,Ge F,Li Z

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Since the introduction of biologic treatment in rheumatoid arthritis (RA), disease activity and treatment modalities have changed substantially. The current provision and developments in recent years are analyzed with annual data from the National Database of the Collaborative Arthritis Centers in Germany. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Albrecht K,Huscher D,Eidner T,Kleinert S,Späthling-Mestekemper S,Bischoff S,Zink A

更新日期：2017-02-01 00:00:00