Social isolation prevents exercise-induced proliferation of hippocampal progenitor cells in female rats.

abstract：:Processing of multimodal sensory information by the morphological subdivisions of the hippocampus and its input and output structures was investigated in unanesthetized rabbits by extracellular recording of neuronal activity. Analysis shows principal differences between CA3 neurons with uniform multimodal, mainly inhi...

journal_title：Hippocampus

authors： Vinogradova OS

更新日期：2001-01-01 00:00:00

abstract：:Subjective and objective memory deficits represent a frequent and ill-understood aspect of multiple sclerosis (MS), and a significant cause of disability and quality of life reduction. The aim of the study is to verify the role of hippocampal and temporal associative fibers' damage in MS-related memory complaints. To ...

journal_title：Hippocampus

authors： Pardini M,Bergamino M,Bommarito G,Bonzano L,Luigi Mancardi G,Roccatagliata L

更新日期：2014-04-01 00:00:00

abstract：:Watermaze tests of place learning and memory in rodents and corresponding reverse-translated human paradigms in real or virtual environments are key tools to study hippocampal function. In common variants, the animal or human participant has to find a hidden goal that remains in the same place over many trials, allowi...

journal_title：Hippocampus

authors： Buckley MG,Bast T

更新日期：2018-11-01 00:00:00

abstract：:Reorganization of excitatory and inhibitory circuits in the hippocampal formation following seizure-induced neuronal loss has been proposed to underlie the development of chronic seizures in temporal lobe epilepsy (TLE). Here, we investigated whether specific morphological alterations of the GABAergic system can be re...

journal_title：Hippocampus

authors： André V,Marescaux C,Nehlig A,Fritschy JM

更新日期：2001-01-01 00:00:00

abstract：:Hippocampal neurons are selectively active when a rat occupies restricted locations in an environment. These place cells derive their specificity from a multitude of sources, including idiothetic cues and sensory input derived from both distal and local landmarks. Most experiments have attempted to dissociate the rela...

journal_title：Hippocampus

authors： Knierim JJ,Rao G

更新日期：2003-01-01 00:00:00

abstract：:A large body of neuroscientific work indicates that exposure to experienced stress causes damage to both cortical and hippocampal cells and results in impairments to cognitive abilities associated with these structures. Similarly, work within the domain of cognitive aging demonstrates that elderly participants who rep...

journal_title：Hippocampus

authors： Marshall AC,Cooper NR,Geeraert N

更新日期：2016-03-01 00:00:00

abstract：:Previous research has revealed that the functional components of spatial cognition are lateralized in the forebrain of birds, including the hippocampal formation (HF). To investigate how HF cells in the left and right avian brain may differentially participate in representations of space, we recorded single-units from...

journal_title：Hippocampus

authors： Siegel JJ,Nitz D,Bingman VP

更新日期：2006-01-01 00:00:00

abstract：:Alzheimer's disease (AD) and ageing are associated with impaired learning and memory, and recent findings point toward modulating chromatin remodeling through histone acetylation as a promising therapeutic strategy. Here we report that systemic administration of the HDAC inhibitor 4-phenylbutyrate (PBA) reinstated fea...

journal_title：Hippocampus

authors： Ricobaraza A,Cuadrado-Tejedor M,Marco S,Pérez-Otaño I,García-Osta A

更新日期：2012-05-01 00:00:00

abstract：:The ERK/MAPK signaling pathway has been extensively studied in the context of learning and memory. Defects in this pathway underlie genetic diseases associated with intellectual disability, including impaired learning and memory. Numerous studies have investigated the impact of acute ERK/MAPK inhibition on long-term p...

journal_title：Hippocampus

authors： Vithayathil J,Pucilowska J,Friel D,Landreth GE

更新日期：2017-12-01 00:00:00

abstract：:Rats were trained on an operant conditional discrimination in which an ambiguous stimulus (X) indicated both the occasions on which responding in the presence of a second cue (A) would be reinforced and the occasions on which responding in the presence of a third cue (B) would not be reinforced (X --> A+, A-, X --> B-...

journal_title：Hippocampus

authors： Han JS,Gallagher M,Holland P

更新日期：1998-01-01 00:00:00

abstract：:Sleep is important for memory consolidation, and an abundant literature suggests that reactivation in the hippocampus during sleep is instrumental to this process. Yet, the current interpretation of activity during sharp-waves ripples (SWRs), as replay of wake experiences, relies on hypotheses that, while widely accep...

journal_title：Hippocampus

authors： Laventure S,Benchenane K

更新日期：2020-01-01 00:00:00

abstract：:The conditioned cue preference (CCP) task was used to study the ability of rats to discriminate between spatial locations. Food-deprived rats explored an eight-arm radial maze with no food present (pre-exposure). On subsequent days, they were alternately confined in one arm of the maze with food and in another arm wit...

journal_title：Hippocampus

authors： Gaskin S,Chai SC,White NM

更新日期：2005-01-01 00:00:00

abstract：:In all species examined, the dentate gyrus develops over an extended period that begins during gestation and continues up to adulthood. The aim of this study was to investigate the pattern of postnatal cell production in the dentate gyrus of the guinea pig, a rodent whose brain development has features more closely re...

journal_title：Hippocampus

authors： Guidi S,Ciani E,Severi S,Contestabile A,Bartesaghi R

更新日期：2005-01-01 00:00:00

abstract：:We aimed at identifying the cerebral structures whose synaptic function subserves the recollection of lifetime's episodic autobiographical memory (AM) via autonoetic consciousness. Twelve healthy middle-aged subjects (mean age: 59 years +/- 2.5) underwent a specially designed cognitive test to assess the ability to re...

journal_title：Hippocampus

authors： Piolino P,Desgranges B,Hubert V,Bernard FA,Matuszewski V,Chételat G,Baron JC,Eustache F

更新日期：2008-01-01 00:00:00

abstract：:Although a large body of evidence indicates that sleep plays an important role in learning and memory processes, the actual existence of a sleep-dependent spatial memory consolidation has been not firmly established. Here, by using a computerized 3D virtual navigation tool, we were able to show that topographical orie...

journal_title：Hippocampus

authors： Ferrara M,Iaria G,Tempesta D,Curcio G,Moroni F,Marzano C,De Gennaro L,Pacitti C

更新日期：2008-01-01 00:00:00

abstract：:Dorsoventral lesion studies of the hippocampus have indicated that the dorsal axis of the hippocampus is important for spatial processing and the ventral axis of the hippocampus is important for olfactory learning and memory and anxiety. There is some evidence to suggest that the ventral CA3 and ventral CA1 conduct pa...

journal_title：Hippocampus

authors： Weeden CS,Hu NJ,Ho LU,Kesner RP

更新日期：2014-05-01 00:00:00

abstract：:Neurons in the supramammillary nucleus (SUM) of urethane-anesthetized rats fire rhythmically in synchrony with hippocampal theta rhythm. As these neurons project to the septum and hippocampus, it is generally assumed that their role is to mediate ascending activation, leading to the hippocampal theta rhythm. However, ...

journal_title：Hippocampus

authors： Kocsis B,Kaminski M

更新日期：2006-01-01 00:00:00

abstract：:We analyzed intracranial electroencephalographic (EEG) recordings from the medial temporal lobes of 12 epilepsy patients during a continuous word recognition paradigm, contrasting trials of correctly recognized repeated words (hits) and correctly identified new words (correct rejections). Using a wavelet-based analysi...

journal_title：Hippocampus

authors： Mormann F,Fell J,Axmacher N,Weber B,Lehnertz K,Elger CE,Fernández G

更新日期：2005-01-01 00:00:00

abstract：:By acting on serotonin 5-HT2A receptors (5-HT2A Rs), serotonergic psychedelic drugs induce perceptual and visual hallucinations by increasing neuronal excitability and altering visual-evoked neuronal responses. The present study was designed to examine whether the perceptual alterations induced by a serotonergic psych...

journal_title：Hippocampus

authors： Zhang G,Cinalli D,Stackman RW Jr

更新日期：2017-05-01 00:00:00

abstract：:People retain more new verbal episodic information for at least 7 days if they rest for a few minutes after learning than if they attend to new information. It is hypothesized that rest allows for superior consolidation of new memories. In rodents, rest periods promote hippocampal replay of a recently travelled route,...

journal_title：Hippocampus

authors： Craig M,Dewar M,Della Sala S,Wolbers T

更新日期：2015-09-01 00:00:00

abstract：:In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the entorhinal cortex with a focus on the concept of parallel cortical connectivity streams. The concept of two entorhinal areas, the lateral and medial entorhinal cortex, belonging to two parallel input-output streams mediati...

journal_title：Hippocampus

authors： Nilssen ES,Doan TP,Nigro MJ,Ohara S,Witter MP

更新日期：2019-12-01 00:00:00

abstract：:We have previously shown that, in HEK 293 cells, overexpression of acidic calponin, an actin-binding protein, induces remodeling of actin filaments, leading to a change in cell morphology. In addition, this protein is found in dendritic spines of adult hippocampal neurons. We hypothesized that this protein plays a rol...

journal_title：Hippocampus

authors： Ferhat L,Esclapez M,Represa A,Fattoum A,Shirao T,Ben-Ari Y

更新日期：2003-01-01 00:00:00

abstract：:Cocaine induces an increase in hippocampal and nucleus accumbens (Nac) serotonin (5-HT) concentration parallel to locomotor activation. Both effects can be modulated by systemic 5-HT(1A)-receptor agonism/antagonism. Given the contribution of the hippocampus to spontaneous behavioral activity, these observations sugges...

journal_title：Hippocampus

authors： Müller CP,Thönnessen H,Barros M,Tomaz C,Carey RJ,Huston JP

更新日期：2004-01-01 00:00:00

abstract：:Evidence for morphological substrates of long-term changes in synaptic efficacy is controversial, partly because it is difficult to employ an unambiguous control. We have used a high-frequency stimulation protocol in vivo to induce long-term potentiation (LTP) in the hippocampal dentate gyrus of aged (22-month-old) ra...

journal_title：Hippocampus

authors： Dhanrajan TM,Lynch MA,Kelly A,Popov VI,Rusakov DA,Stewart MG

更新日期：2004-01-01 00:00:00

abstract：:Paired-pulse depression (PPD), a short-term neural plasticity, was studied in hippocampal CA1 of urethane-anesthetized rats in vivo, using field potential recordings and current source density analysis. PPD was robust when an ipsilateral CA3 (iCA3) conditioning pulse of moderate stimulus intensity was followed 30-200 ...

journal_title：Hippocampus

authors： Leung LS,Peloquin P,Canning KJ

更新日期：2008-01-01 00:00:00

abstract：:We have previously shown that exposing rats to a relatively high dose of ethanol during early postnatal life can result in an alteration in spatial learning ability. The hippocampal formation is known to be involved in the control of this ability. The purpose of the present study was to determine whether exposure of r...

journal_title：Hippocampus

authors： Miki T,Harris SJ,Wilce PA,Takeuchi Y,Bedi KS

更新日期：2004-01-01 00:00:00

abstract：:Key pathological features of Parkinson's Disease (PD) include the progressive degeneration of midbrain dopaminergic (DA) neurons and hindbrain noradrenergic (NA) neurons. The loss of DA neurons has been extensively studied and is the main cause of motor dysfunction. Importantly, however, there are a range of 'non-move...

journal_title：Hippocampus

authors： Ermine CM,Wright JL,Frausin S,Kauhausen JA,Parish CL,Stanic D,Thompson LH

更新日期：2018-05-01 00:00:00

abstract：:The goal of the present research was to assess the degree to which a pattern completion process operates in cue-induced relapse to cocaine-seeking behavior. Using a novel cue-preference version of the place preference task, rats were administered cocaine or saline, which resulted in a preference for the cocaine-paired...

journal_title：Hippocampus

authors： Kesner RP,Kirk RA,Clark JK,Moore A,Keefe K

更新日期：2016-07-01 00:00:00

abstract：:Neurogenesis persists in the adult rat rostral forebrain subventricular zone (SVZ) and is stimulated by status epilepticus (SE). More caudal SVZ (cSVZ) neural progenitors migrate to the hippocampus after ischemic injury and contribute to CA1 pyramidal cell regeneration. Because SE also damages the hippocampus, we exam...

journal_title：Hippocampus

authors： Parent JM,von dem Bussche N,Lowenstein DH

更新日期：2006-01-01 00:00:00

abstract：:The mammalian hippocampus plays a key role in spatial learning and memory, but the exact nature of the hippocampal representation of space is still being explored. Recently, there has been a fair amount of success in modeling hippocampal spatial maps in rats, assuming a topological perspective on spatial information p...

journal_title：Hippocampus

authors： Hoffman K,Babichev A,Dabaghian Y

更新日期：2016-10-01 00:00:00