Fatal cytisine intoxication and analysis of biological samples with LC-MS/MS.

Abstract:

:We report about a fatal cytisine intoxication in a 20-year-old man who, according to his mother, had drunken tea prepared from plant material of Laburnum anagyroides with the toxic pyridine-like alkaloid as ingredient, which exhibits pharmacological effects similar to nicotine. Using a liquid chromatographic-mass spectrometric (LC-MS) procedure cytisine was quantified in post-mortem specimens. By exclusion of other causes of death an intoxication was determined as the cause of death with respiratory failure as the pathophysiological mechanism.

journal_name

Forensic Sci Int

authors

Musshoff F,Madea B

doi

10.1016/j.forsciint.2009.01.011

subject

Has Abstract

pub_date

2009-04-15 00:00:00

pages

e1-4

issue

1-3

eissn

0379-0738

issn

1872-6283

pii

S0379-0738(09)00037-1

journal_volume

186

pub_type

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