Expression profiles of urbilaterian genes uniquely shared between honey bee and vertebrates.

abstract：BACKGROUND:Moraxella catarrhalis is an important pathogen that often causes otitis media in children, a disease that is not currently vaccine preventable. Asymptomatic colonisation of the human upper respiratory tract is common and lack of clearance by the immune system is likely due to the emergence of seroresistant g...

journal_title：BMC genomics

authors： Ariff A,Wise MJ,Kahler CM,Tay CY,Peters F,Perkins TT,Chang BJ

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:In many eukaryotes, microRNAs (miRNAs) bind to complementary sites in the 3'-untranslated regions (3'-UTRs) of target messenger RNAs (mRNAs) and regulate their expression at the stage of translation. Recent studies have revealed that many miRNAs are evolutionarily conserved; however, the evolution of their t...

journal_title：BMC genomics

authors： Takane K,Fujishima K,Watanabe Y,Sato A,Saito N,Tomita M,Kanai A

更新日期：2010-02-09 00:00:00

abstract：BACKGROUND:Among viruses, bacteriophages are a group of special interest due to their capacity of infecting bacteria that are important for biotechnology and human health. Composting is a microbial-driven process in which complex organic matter is converted into humus-like substances. In thermophilic composting, the de...

journal_title：BMC genomics

authors： Amgarten D,Martins LF,Lombardi KC,Antunes LP,de Souza APS,Nicastro GG,Kitajima EW,Quaggio RB,Upton C,Setubal JC,da Silva AM

更新日期：2017-05-04 00:00:00

abstract：BACKGROUND:Bloodstream malaria parasites require Ca++ for their development, but the sites and mechanisms of Ca++ utilization are not well understood. We hypothesized that there may be differences in Ca++ uptake or utilization by genetically distinct lines of P. falciparum. These differences, if identified, may provide...

journal_title：BMC genomics

authors： Apolis L,Olivas J,Srinivasan P,Kushwaha AK,Desai SA

更新日期：2019-01-16 00:00:00

abstract：BACKGROUND:Many reptiles exhibit temperature-dependent sex determination (TSD). The initial cue in TSD is incubation temperature, unlike genotypic sex determination (GSD) where it is determined by the presence of specific alleles (or genetic loci). We used patterns of gene expression to identify candidates for genes wi...

journal_title：BMC genomics

authors： Chojnowski JL,Braun EL

更新日期：2012-07-15 00:00:00

abstract：BACKGROUND:The ribosome is a central player in the translation system, which in mammals consists of four RNA species and 79 ribosomal proteins (RPs). The control mechanisms of gene expression and the functions of RPs are believed to be identical. Most RP genes have common promoters and were therefore assumed to have a ...

journal_title：BMC genomics

authors： Ishii K,Washio T,Uechi T,Yoshihama M,Kenmochi N,Tomita M

更新日期：2006-02-28 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：BMC genomics

authors： Onizuka S,Yamazaki Y,Park SJ,Sugimoto T,Sone Y,Sjöqvist S,Usui M,Takeda A,Nakai K,Nakashima K,Iwata T

更新日期：2020-08-11 00:00:00

abstract：BACKGROUND:Defensins are important components of innate immunity to combat bacterial and viral infections, and can even elicit antitumor responses. Clusters of defensin (DEF) genes are located in a 2 Mb range of the human chromosome 8p23.1. This DEF locus, however, represents one of the regions in the euchromatic part ...

journal_title：BMC genomics

authors： Taudien S,Galgoczy P,Huse K,Reichwald K,Schilhabel M,Szafranski K,Shimizu A,Asakawa S,Frankish A,Loncarevic IF,Shimizu N,Siddiqui R,Platzer M

更新日期：2004-12-10 00:00:00

abstract：BACKGROUND:To generate specific transcript profiles, one must isolate homogenous cell populations using techniques that often yield small amounts of RNA, requiring researchers to employ RNA amplification methods. The data generated by using these methods must be extensively evaluated to determine any technique dependen...

journal_title：BMC genomics

authors： Gold D,Coombes K,Medhane D,Ramaswamy A,Ju Z,Strong L,Koo JS,Kapoor M

更新日期：2004-01-06 00:00:00

abstract：BACKGROUND:The problem of supervised DNA sequence classification arises in several fields of computational molecular biology. Although this problem has been extensively studied, it is still computationally challenging due to size of the datasets that modern sequencing technologies can produce. RESULTS:We introduce CLA...

journal_title：BMC genomics

authors： Ounit R,Wanamaker S,Close TJ,Lonardi S

更新日期：2015-03-25 00:00:00

abstract：BACKGROUND:The trypanosomatids Leishmania major, Trypanosoma brucei and Trypanosoma cruzi cause some of the most debilitating diseases of humankind: cutaneous leishmaniasis, African sleeping sickness, and Chagas disease. These protozoa possess complex life cycles that involve development in mammalian and insect hosts, ...

journal_title：BMC genomics

authors： Parsons M,Worthey EA,Ward PN,Mottram JC

更新日期：2005-09-15 00:00:00

abstract：BACKGROUND:Dermal papilla cells (DPCs), the "signaling center" of hair follicle (HF), delicately master continual growth of hair in mammals including cashmere, the fine fiber annually produced by secondary HF embedded in cashmere goat skins. Such unparalleled capacity bases on their exquisite character in instructing t...

journal_title：BMC genomics

authors： Ma S,Wang Y,Zhou G,Ding Y,Yang Y,Wang X,Zhang E,Chen Y

更新日期：2019-06-20 00:00:00

abstract：BACKGROUND:Genome-wide association studies have revealed associations between single-nucleotide polymorphisms (SNPs) and phenotypes such as disease symptoms and drug tolerance. To address the small sample size for rare variants, association studies tend to group gene or pathway level variants and evaluate the effect on...

journal_title：BMC genomics

authors： Hasegawa T,Kojima K,Kawai Y,Misawa K,Mimori T,Nagasaki M

更新日期：2016-09-21 00:00:00

abstract：BACKGROUND:Cotton (Gossypium spp.) is commonly grouped into eight diploid genomic groups and an allotetraploid genomic group, AD. The mitochondrial genomes supply new information to understand both the evolution process and the mechanism of cytoplasmic male sterility. Based on previously released mitochondrial genomes ...

journal_title：BMC genomics

authors： Chen Z,Nie H,Wang Y,Pei H,Li S,Zhang L,Hua J

更新日期：2017-11-13 00:00:00

abstract：BACKGROUND:Codon usage analysis has been a classical topic for decades and has significances for studies of evolution, mRNA translation, and new gene discovery, etc. While the codon usage varies among different members of the plant kingdom, indicating the necessity for species-specific study, this work has mostly been ...

journal_title：BMC genomics

authors： Feng C,Xu CJ,Wang Y,Liu WL,Yin XR,Li X,Chen M,Chen KS

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Detoxification in the liver involves activation of nuclear receptors, such as the constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic metabolism. Frequently, the metabolism of endobiotics is also modulated, resulting in potentially harmful effects. We therefore used 1,4-Bis ...

journal_title：BMC genomics

authors： Rezen T,Tamasi V,Lövgren-Sandblom A,Björkhem I,Meyer UA,Rozman D

更新日期：2009-08-19 00:00:00

abstract：BACKGROUND:Microarrays have revolutionized breast cancer (BC) research by enabling studies of gene expression on a transcriptome-wide scale. Recently, RNA-Sequencing (RNA-Seq) has emerged as an alternative for precise readouts of the transcriptome. To date, no study has compared the ability of the two technologies to q...

journal_title：BMC genomics

authors： Fumagalli D,Blanchet-Cohen A,Brown D,Desmedt C,Gacquer D,Michiels S,Rothé F,Majjaj S,Salgado R,Larsimont D,Ignatiadis M,Maetens M,Piccart M,Detours V,Sotiriou C,Haibe-Kains B

更新日期：2014-11-21 00:00:00

abstract：BACKGROUND:The importance of Indian germplasm as origin and primary center of diversity of cultivated melon is widely accepted. Genetic diversity of several collections from Indian has been studied previously, although an integrated analysis of these collections in a global diversity perspective has not been possible. ...

journal_title：BMC genomics

authors： Gonzalo MJ,Díaz A,Dhillon NPS,Reddy UK,Picó B,Monforte AJ

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland. Comparative analysis of the complete genome sequence of S. uberis strain...

journal_title：BMC genomics

authors： Ward PN,Holden MT,Leigh JA,Lennard N,Bignell A,Barron A,Clark L,Quail MA,Woodward J,Barrell BG,Egan SA,Field TR,Maskell D,Kehoe M,Dowson CG,Chanter N,Whatmore AM,Bentley SD,Parkhill J

更新日期：2009-01-28 00:00:00

abstract：BACKGROUND:Transcriptome expression analysis in peanut to date has been limited to a relatively small set of genes and only recently has a significant number of ESTs been released into the public domain. Utilization of these ESTs for oligonucleotide microarrays provides a means to investigate large-scale transcript res...

journal_title：BMC genomics

authors： Payton P,Kottapalli KR,Rowland D,Faircloth W,Guo B,Burow M,Puppala N,Gallo M

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:Subtilisin/kexin-like proprotein convertase (PCSK) enzymes have important regulatory function in a wide variety of biological processes. PCSKs proteolytically process at a target sequence that contains basic amino acids arginine and lysine, which results in functional maturation of the target protein. In vit...

journal_title：BMC genomics

authors： Turpeinen H,Kukkurainen S,Pulkkinen K,Kauppila T,Ojala K,Hytönen VP,Pesu M

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Wood formation affects the chemical and physical properties of wood, and thus affects its utility as a building material or a feedstock for biofuels, pulp and paper. To obtain genome-wide insights on the transcriptome changes and regulatory networks in wood formation, we used high-throughput RNA sequencing t...

journal_title：BMC genomics

authors： Chen J,Chen B,Zhang D

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:Genome-scale metabolic models (GSMM) integrating transcriptomics have been widely used to study cancer metabolism. This integration is achieved through logical rules that describe the association between genes, proteins, and reactions (GPRs). However, current gene-to-reaction formulation lacks the stoichiome...

journal_title：BMC genomics

authors： Marín de Mas I,Torrents L,Bedia C,Nielsen LK,Cascante M,Tauler R

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Characterizing large genomic variants is essential to expanding the research and clinical applications of genome sequencing. While multiple data types and methods are available to detect these structural variants (SVs), they remain less characterized than smaller variants because of SV diversity, complexity,...

journal_title：BMC genomics

authors： English AC,Salerno WJ,Hampton OA,Gonzaga-Jauregui C,Ambreth S,Ritter DI,Beck CR,Davis CF,Dahdouli M,Ma S,Carroll A,Veeraraghavan N,Bruestle J,Drees B,Hastie A,Lam ET,White S,Mishra P,Wang M,Han Y,Zhang F,Stankie

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:The importance of transposable elements (TEs) in the genomic remodeling and chromosomal rearrangements that accompany lineage diversification in vertebrates remains the subject of debate. The major impediment to understanding the roles of TEs in genome evolution is the lack of comparative and integrative ana...

journal_title：BMC genomics

authors： Auvinet J,Graça P,Belkadi L,Petit L,Bonnivard E,Dettaï A,Detrich WH 3rd,Ozouf-Costaz C,Higuet D

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Mapping DNaseI hypersensitive sites is commonly used to identify regulatory regions in the genome. However, currently available methods are either time consuming and laborious, expensive or require large numbers of cells. We aimed to develop a quick and straightforward method for the analysis of DNaseI hyper...

journal_title：BMC genomics

authors： Ohnesorg T,Eggers S,Leonhard WN,Sinclair AH,White SJ

更新日期：2009-09-04 00:00:00

abstract：BACKGROUND:Integrons are genomic elements that mediate horizontal gene transfer by inserting and removing genetic material using site-specific recombination. Integrons are commonly found in bacterial genomes, where they maintain a large and diverse set of genes that plays an important role in adaptation and evolution. ...

journal_title：BMC genomics

authors： Buongermino Pereira M,Österlund T,Eriksson KM,Backhaus T,Axelson-Fisk M,Kristiansson E

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:As economically relevant traits, feeding behavior and food preference domestication determine production cost and profitability. Although there are intensive research efforts on feeding behavior and food intake, little is known about food preference. Mandarin fish accept only live prey fish and refuse dead p...

journal_title：BMC genomics

authors： He S,Liang XF,Sun J,Li L,Yu Y,Huang W,Qu CM,Cao L,Bai XL,Tao YX

更新日期：2013-09-05 00:00:00

abstract：BACKGROUND:Mitochondrial genomes comprise a small but critical component of the total DNA in eukaryotic organisms. They encode several key proteins for the cell's major energy producing apparatus, the mitochondrial respiratory chain. Additionally, their nucleotide and amino acid sequences are of great utility as marker...

journal_title：BMC genomics

authors： Lloyd RE,Foster PG,Guille M,Littlewood DT

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:In clinical and basic research custom panels for transcript profiling are gaining importance because only project specific informative genes are interrogated. This approach reduces costs and complexity of data analysis and allows multiplexing of samples. Polymerase-chain-reaction (PCR) based TaqMan assays ha...

journal_title：BMC genomics

authors： Zhang JD,Schindler T,Küng E,Ebeling M,Certa U

更新日期：2014-07-05 00:00:00