Abstract:
BACKGROUND:Drosophila melanogaster females show changes in behavior and physiology after mating that are thought to maximize the number of progeny resulting from the most recent copulation. Sperm and seminal fluid proteins induce post-mating changes in females, however, very little is known about the resulting gene expression changes in female head and central nervous system tissues that contribute to the post-mating response. RESULTS:We determined the temporal gene expression changes in female head tissues 0-2, 24, 48 and 72 hours after mating. Females from each time point had a unique post-mating gene expression response, with 72 hours post-mating having the largest number of genes with significant changes in expression. At most time points, genes expressed in the head fat body that encode products involved in metabolism showed a marked change in expression. Additional analysis of gene expression changes in dissected brain tissues 24 hours post-mating revealed changes in transcript abundance of many genes, notably, the reduced transcript abundance of genes that encode ion channels. CONCLUSIONS:Substantial changes occur in the regulation of many genes in female head tissues after mating, which might underlie aspects of the female post-mating response. These results provide new insights into the physiological and metabolic changes that accompany changes in female behaviors.
journal_name
BMC Genomicsjournal_title
BMC genomicsauthors
Dalton JE,Kacheria TS,Knott SR,Lebo MS,Nishitani A,Sanders LE,Stirling EJ,Winbush A,Arbeitman MNdoi
10.1186/1471-2164-11-541subject
Has Abstractpub_date
2010-10-06 00:00:00pages
541issn
1471-2164pii
1471-2164-11-541journal_volume
11pub_type
杂志文章相关文献
BMC GENOMICS文献大全abstract:BACKGROUND:Bombyx mori was domesticated from the Chinese wild silkworm, Bombyx mandarina. Wild and domestic silkworms are good models in which to investigate genes related to silk protein synthesis that may be differentially expressed in silk glands, because their silk productions are very different. Here we used the m...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1287-9
更新日期:2015-02-06 00:00:00
abstract:BACKGROUND:Cancer is a complex disease driven by somatic genomic alterations (SGAs) that perturb signaling pathways and consequently cellular function. Identifying patterns of pathway perturbations would provide insights into common disease mechanisms shared among tumors, which is important for guiding treatment and pr...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-017-3494-z
更新日期:2017-03-14 00:00:00
abstract:BACKGROUND:Cichlid fishes have evolved remarkably diverse reproductive, social, and feeding behaviors. Cell-to-cell signaling molecules, notably neuropeptides and peptide hormones, are known to regulate these behaviors across vertebrates. This class of signaling molecules derives from prohormone genes that have undergo...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-2914-9
更新日期:2016-08-19 00:00:00
abstract:BACKGROUND:Panax notoginseng (Burk) F.H. Chen is important medicinal plant of the Araliacease family. Triterpene saponins are the bioactive constituents in P. notoginseng. However, available genomic information regarding this plant is limited. Moreover, details of triterpene saponin biosynthesis in the Panax species ar...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-S5-S5
更新日期:2011-12-23 00:00:00
abstract:BACKGROUND:The ballan wrasse (Labrus bergylta) belongs to a large teleost family containing more than 600 species showing several unique evolutionary traits such as lack of stomach and hermaphroditism. Agastric fish are found throughout the teleost phylogeny, in quite diverse and unrelated lineages, indicating stomach ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-4570-8
更新日期:2018-03-06 00:00:00
abstract:BACKGROUND:For centuries roses have been selected based on a number of traits. Little information exists on the genetic and molecular basis that contributes to these traits, mainly because information on expressed genes for this economically important ornamental plant is scarce. RESULTS:Here, we used a combination of ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-638
更新日期:2012-11-20 00:00:00
abstract:BACKGROUND:Fitness epistasis, the interaction effect of genes at different loci on fitness, makes an important contribution to adaptive evolution. Although fitness interaction evidence has been observed in model organisms, it is more difficult to detect and remains poorly understood in human populations as a result of ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-06874-7
更新日期:2020-07-11 00:00:00
abstract:BACKGROUND:A major goal in the post-genomic era is to identify and characterise disease susceptibility genes and to apply this knowledge to disease prevention and treatment. Rodents and humans have remarkably similar genomes and share closely related biochemical, physiological and pathological pathways. In this work we...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-5-28
更新日期:2004-04-29 00:00:00
abstract:BACKGROUND:The formation of flowers is one of the main model systems to elucidate the molecular mechanisms that control developmental processes in plants. Although several studies have explored gene expression during flower development in the model plant Arabidopsis thaliana on a genome-wide scale, a continuous series ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1699-6
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Artificial insemination and genetic selection are major factors contributing to population stratification in dairy cattle. In this study, we analyzed the effect of sample stratification and the effect of stratification correction on results of a dairy genome-wide association study (GWAS). Three methods for s...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-536
更新日期:2012-10-06 00:00:00
abstract:BACKGROUND:Despite the importance of chromosomal translocations in the initiation and/or progression of cancer, a comprehensive catalog of translocation breakpoints in which these are precisely located on the reference sequence of the human genome is not available at present. DESCRIPTION:We have created a database tha...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-8-33
更新日期:2007-01-26 00:00:00
abstract:BACKGROUND:The orange pigmentation of the agar cultures of many Fusarium species is due to the production of carotenoids, terpenoid pigments whose synthesis is stimulated by light. The genes of the carotenoid pathway and their regulation have been investigated in detail in Fusarium fujikuroi. In this and other Fusarium...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-019-5430-x
更新日期:2019-01-21 00:00:00
abstract:BACKGROUND:Siraitia grosvenorii (Luohanguo) is an herbaceous perennial plant native to southern China and most prevalent in Guilin city. Its fruit contains a sweet, fleshy, edible pulp that is widely used in traditional Chinese medicine. The major bioactive constituents in the fruit extract are the cucurbitane-type tri...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-343
更新日期:2011-07-05 00:00:00
abstract:BACKGROUND:Bacterial vaginosis (BV) is an ecological disorder of the vaginal microbiota that affects millions of women annually, and is associated with numerous adverse health outcomes including pre-term birth and the acquisition of sexually transmitted infections. However, little is known about the overall structure a...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-11-488
更新日期:2010-09-07 00:00:00
abstract:BACKGROUND:Crustaceans have been studied extensively as model systems for nervous system function from single neuron properties to behavior. However, lack of molecular sequence information and tools have slowed the adoption of these physiological systems as molecular model systems. In this study, we sequenced and perfo...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-3215-z
更新日期:2016-11-04 00:00:00
abstract:BACKGROUND:Genome-wide expression profiles are altered during biological aging and can describe molecular regulation of tissue degeneration. Age-regulated mRNA expression trends from cross-sectional studies could describe how aging progresses. We developed a novel statistical methodology to identify age-regulated expre...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-132
更新日期:2014-02-14 00:00:00
abstract:BACKGROUND:Oxidative stress is a consequence of normal and abnormal cellular metabolism and is linked to the development of human diseases. The effective functioning of the pathway responding to oxidative stress protects the cellular DNA against oxidative damage; conversely the failure of the oxidative stress response ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-S6-S4
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Hemolymph plays key roles in honey bee molecule transport, immune defense, and in monitoring the physiological condition. There is a lack of knowledge regarding how the proteome achieves these biological missions for both the western and eastern honey bees (Apis mellifera and Apis cerana). A time-resolved pr...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-563
更新日期:2014-07-05 00:00:00
abstract:BACKGROUND:High Density Oligonucleotide arrays (HDONAs), such as the Affymetrix HG-U133A GeneChip, use sets of probes chosen to match specified genes, with the expectation that if a particular gene is highly expressed then all the probes in that gene's probe set will provide a consistent message signifying the gene's p...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-9-613
更新日期:2008-12-18 00:00:00
abstract:BACKGROUND:Genetic association studies that seek to explain the inheritance of complex traits typically fail to explain a majority of the heritability of the trait under study. Thus, we are left with a gap in the map from genotype to phenotype. Several approaches have been used to fill this gap, including those that at...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-6739-1
更新日期:2020-05-04 00:00:00
abstract:BACKGROUND:The mitochondrial genomes of higher plants vary remarkably in size, structure and sequence content, as demonstrated by the accumulation and activity of repetitive DNA sequences. Incompatibility between mitochondrial genome and nuclear genome leads to non-functional male reproductive organs and results in cyt...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-5122-y
更新日期:2018-10-26 00:00:00
abstract:BACKGROUND:Currently, diabetes has become one of the leading causes of death worldwide. Fasting plasma glucose (FPG) levels that are higher than optimal, even if below the diagnostic threshold of diabetes, can also lead to increased morbidity and mortality. Here we intend to study the magnitude of the genetic influence...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-06898-z
更新日期:2020-07-18 00:00:00
abstract:BACKGROUND:Prediction methods are increasingly used in biosciences to forecast diverse features and characteristics. Binary two-state classifiers are the most common applications. They are usually based on machine learning approaches. For the end user it is often problematic to evaluate the true performance and applica...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-S4-S2
更新日期:2012-06-18 00:00:00
abstract:BACKGROUND:Genomes store information for building and maintaining organisms. Complete sequencing of many genomes provides the opportunity to study and compare global information properties of those genomes. RESULTS:We have analyzed aspects of the information content of Homo sapiens, Mus musculus, Drosophila melanogast...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-9-509
更新日期:2008-10-30 00:00:00
abstract:BACKGROUND:gammadelta T cells differ from alphabeta T cells with regard to the types of antigen with which their T cell receptors interact; gammadelta T cell antigens are not necessarily peptides nor are they presented on MHC. Cattle are considered a "gammadelta T cell high" species indicating they have an increased pr...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-11-100
更新日期:2010-02-09 00:00:00
abstract:BACKGROUND:Cells transformed by human adenoviruses (Ad) exhibit differential capacities to induce tumours in immunocompetent rodents; for example, Ad12-transformed rodent cells are oncogenic whereas Ad5-transformed cells are not. The E1A gene determines oncogenic phenotype, is a transcriptional regulator and dysregulat...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-10-67
更新日期:2009-02-06 00:00:00
abstract:BACKGROUND:In plants carotenoids play an important role in the photosynthetic process and photo-oxidative protection, and are the substrate for the synthesis of abscisic acid and strigolactones. In addition to their protective role as antioxidants and precursors of vitamin A, in wheat carotenoids are important as they ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-3395-6
更新日期:2017-01-31 00:00:00
abstract:BACKGROUND:The P1B-ATPase subfamily is an important group involved in transporting heavy metals and has been extensively studied in model plants, such as Arabidopsis thaliana and Oryza sativa. Emerging evidence indicates that one homolog in Glycine max is also involved in cadmium (Cd) stress, but the gene family has no...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-2730-2
更新日期:2016-05-20 00:00:00
abstract:BACKGROUND:Plants respond to low temperature through an intricately coordinated transcriptional network. The CBF/DREB-regulated network of genes has been shown to play a prominent role in freeze-tolerance of Arabidopsis through the process of cold acclimation (CA). Recent evidence also showed that the CBF/DREB regulon ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-8-175
更新日期:2007-06-18 00:00:00
abstract:BACKGROUND:Interactions between fish and pathogens, that may be harmless under natural conditions, often result in serious diseases in aquaculture systems. This is especially important due to the fact that the strains used in aquaculture are derived from wild strains that may not have had enough time to adapt to new di...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-541
更新日期:2011-11-02 00:00:00