Annotation and classification of the bovine T cell receptor delta genes.

abstract：BACKGROUND:Endogenous α-synuclein (α-Syn) is involved in many pathophysiological processes in the secondary injury stage after acute spinal cord injury (SCI), and the mechanism governing these functions has not been thoroughly elucidated to date. This research aims to characterize the effect of α-Syn knockdown on trans...

journal_title：BMC genomics

authors： Zeng H,Yu BF,Liu N,Yang YY,Xing HY,Liu XX,Zhou MW

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:Drought is a lifestyle disease. Plant metabolomics has been exercised for understanding the fine-tuning of the potential pathways to surmount the adverse effects of drought stress. A broad spectrum of morphological and metabolic responses from seven Triticeae species including wild types with different droug...

journal_title：BMC genomics

authors： Ullah N,Yüce M,Neslihan Öztürk Gökçe Z,Budak H

更新日期：2017-12-15 00:00:00

abstract：BACKGROUND:The approaches for shotgun-based sequencing of vertebrate genomes are now well-established, and have resulted in the generation of numerous draft whole-genome sequence assemblies. In contrast, the process of refining those assemblies to improve contiguity and increase accuracy (known as 'sequence finishing')...

journal_title：BMC genomics

authors： Blakesley RW,Hansen NF,Gupta J,McDowell JC,Maskeri B,Barnabas BB,Brooks SY,Coleman H,Haghighi P,Ho SL,Schandler K,Stantripop S,Vogt JL,Thomas PJ,NISC Comparative Sequencing Program.,Bouffard GG,Green ED

更新日期：2010-01-11 00:00:00

abstract：BACKGROUND:Modifications of RNA bases have been found in some mRNAs and non-coding RNAs including rRNAs, tRNAs, and snRNAs, where modified bases are important for RNA function. Little is known about RNA base modifications in Arabidopsis thaliana. RESULTS:In the current work, we carried out a bioinformatics analysis of...

journal_title：BMC genomics

authors： Iida K,Jin H,Zhu JK

更新日期：2009-04-09 00:00:00

abstract：BACKGROUND:Advances in human genomics have allowed unprecedented productivity in terms of algorithms, software, and literature available for translating raw next-generation sequence data into high-quality information. The challenges of variant identification in organisms with lower quality reference genomes are less we...

journal_title：BMC genomics

authors： Baes CF,Dolezal MA,Koltes JE,Bapst B,Fritz-Waters E,Jansen S,Flury C,Signer-Hasler H,Stricker C,Fernando R,Fries R,Moll J,Garrick DJ,Reecy JM,Gredler B

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The Abeta-binding alcohol dehydrogenase/17beta-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10) is an enzyme involved in pivotal metabolic processes and in the mitochondrial dysfunction seen in the Alzheimer's disease. Here we use comparative genomic analyses to study the evolution of the HADH2 gene encodin...

journal_title：BMC genomics

authors： Marques AT,Antunes A,Fernandes PA,Ramos MJ

更新日期：2006-08-09 00:00:00

abstract：BACKGROUND:Identification of genes with ascending or descending monotonic expression patterns over time or stages of stem cells is an important issue in time-series microarray data analysis. We propose a method named Monotonic Feature Selector (MFSelector) based on a concept of total discriminating error (DEtotal) to i...

journal_title：BMC genomics

authors： Wang HW,Sun HJ,Chang TY,Lo HH,Cheng WC,Tseng GC,Lin CT,Chang SJ,Pal N,Chung IF

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Two fifths of the world's population is at risk from dengue. The absence of effective drugs and vaccines leaves vector control as the primary intervention tool. Understanding dengue virus (DENV) host interactions is essential for the development of novel control strategies. The availability of genome sequenc...

journal_title：BMC genomics

authors： Guo X,Xu Y,Bian G,Pike AD,Xie Y,Xi Z

更新日期：2010-06-16 00:00:00

abstract：BACKGROUND:High throughput molecular sequencing and increased biospecimen variety have introduced significant informatics challenges for research biorepository infrastructures. We applied a modular system integration approach to develop an operational biorepository management system. This method enables aggregation of ...

journal_title：BMC genomics

authors： Felmeister AS,Masino AJ,Rivera TJ,Resnick AC,Pennington JW

更新日期：2016-08-18 00:00:00

abstract：BACKGROUND:Porcine circovirus type 2 (PCV2) is the causal agent of postweaning multisystemic wasting syndrome (PMWS), which has severely impacted the swine industry worldwide. PCV2 triggers a weak and atypical innate immune response, but the key genes and mechanisms by which the virus interferes with host innate immuni...

journal_title：BMC genomics

authors： Li W,Liu S,Wang Y,Deng F,Yan W,Yang K,Chen H,He Q,Charreyre C,Audoneet JC

更新日期：2013-05-27 00:00:00

abstract：BACKGROUND:Miniature inverted repeat transposable element (MITE) is one type of transposable element (TE), which is largely found in eukaryotic genomes and involved in a wide variety of biological events. However, only few MITEs were proved to be currently active and their physiological function remains largely unknown...

journal_title：BMC genomics

authors： Dong HT,Zhang L,Zheng KL,Yao HG,Chen J,Yu FC,Yu XX,Mao BZ,Zhao D,Yao J,Li DB

更新日期：2012-04-13 00:00:00

abstract：BACKGROUND:Moraxella catarrhalis is an important pathogen that often causes otitis media in children, a disease that is not currently vaccine preventable. Asymptomatic colonisation of the human upper respiratory tract is common and lack of clearance by the immune system is likely due to the emergence of seroresistant g...

journal_title：BMC genomics

authors： Ariff A,Wise MJ,Kahler CM,Tay CY,Peters F,Perkins TT,Chang BJ

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:The Bacillus cereus sensu lato group currently includes seven species (B. cereus, B. anthracis, B. mycoides, B. pseudomycoides, B. thuringiensis, B. weihenstephanensis and B. cytotoxicus) that recent phylogenetic and phylogenomic analyses suggest are likely a single species, despite their varied phenotypes. ...

journal_title：BMC genomics

authors： Scott E 2nd,Dyer DW

更新日期：2012-10-22 00:00:00

abstract：BACKGROUND:One member of the W family of human endogenous retroviruses (HERV) appears to have been functionally adopted by the human host. Nevertheless, a highly diversified and regulated transcription from a range of HERV-W elements has been observed in human tissues and cells. Aberrant expression of members of this f...

journal_title：BMC genomics

authors： Li F,Nellåker C,Yolken RH,Karlsson H

更新日期：2011-01-12 00:00:00

abstract：BACKGROUND:Caixin and Zicaitai (Brassica rapa) belong to Southern and Central China respectively. Zicaitai contains high amount of anthocyanin in leaf and stalk resulting to the purple color. Stalk is the major edible part and stalk color is an economically important trait for the two vegetables. The aim of this study ...

journal_title：BMC genomics

authors： Li GH,Chen HC,Liu JL,Luo WL,Xie DS,Luo SB,Wu TQ,Akram W,Zhong YJ

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:Diversification on the basis of utilization is a hallmark of Beta vulgaris (beet), as well as other crop species. Often, crop improvement and management activities are segregated by crop type, thus preserving unique genome diversity and organization. Full interfertility is typically retained in crosses betwe...

journal_title：BMC genomics

authors： Galewski P,McGrath JM

更新日期：2020-03-02 00:00:00

abstract：BACKGROUND:Despite significant efforts from the research community, an extensive portion of the proteins encoded by human genes lack an assigned cellular function. Most metazoan proteins are composed of structural and/or functional domains, of which many appear in multiple proteins. Once a domain is characterized in on...

journal_title：BMC genomics

authors： Kemmer D,Podowski RM,Arenillas D,Lim J,Hodges E,Roth P,Sonnhammer EL,Höög C,Wasserman WW

更新日期：2006-03-13 00:00:00

abstract：BACKGROUND:Soybean cyst nematode (SCN) is the most economically devastating pathogen of soybean. Two resistance loci, Rhg1 and Rhg4 primarily contribute resistance to SCN race 3 in soybean. Peking and PI 88788 are the two major sources of SCN resistance with Peking requiring both Rhg1 and Rhg4 alleles and PI 88788 only...

journal_title：BMC genomics

authors： Shi Z,Liu S,Noe J,Arelli P,Meksem K,Li Z

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Wheat is the most important staple crop in Afghanistan and accounts for the main part of cereal production. However, wheat production has been unstable during the last decades and the country depends on seed imports. Wheat research in Afghanistan has emphasized releases of new, high-yielding and disease resi...

journal_title：BMC genomics

authors： Dreisigacker S,Sharma RK,Huttner E,Karimov A,Obaidi MQ,Singh PK,Sansaloni C,Shrestha R,Sonder K,Braun HJ

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Malaria, caused by the parasitic protist Plasmodium falciparum, represents a major public health problem in the developing world. The P. falciparum genome has been sequenced, which provides new opportunities for the identification of novel drug targets. Eukaryotic protein kinases (ePKs) form a large family o...

journal_title：BMC genomics

authors： Ward P,Equinet L,Packer J,Doerig C

更新日期：2004-10-12 00:00:00

abstract：BACKGROUND:A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to develop holistic effects characterizations for the wildlife bird model, Northern bobwhite (Colinus virginianus) dosed with the explosives degradation product 2-amino-4,6-dinitrotoluene (2A-DNT)....

journal_title：BMC genomics

authors： Gust KA,Nanduri B,Rawat A,Wilbanks MS,Ang CY,Johnson DR,Pendarvis K,Chen X,Quinn MJ Jr,Johnson MS,Burgess SC,Perkins EJ

更新日期：2015-08-07 00:00:00

abstract：BACKGROUND:Magnesium (Mg)-deficiency is frequently observed in Citrus plantations and is responsible for the loss of productivity and poor fruit quality. Knowledge on the effects of Mg-deficiency on upstream targets is scarce. Seedlings of 'Xuegan' [Citrus sinensis (L.) Osbeck] were irrigated with Mg-deficient (0 mM Mg...

journal_title：BMC genomics

authors： Peng HY,Qi YP,Lee J,Yang LT,Guo P,Jiang HX,Chen LS

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:The human zinc finger protein 191 (ZNF191) is a member of the SCAN domain family of Krüppel-like zinc finger transcription factors. ZNF191 shows 94% identity to its mouse homologue zinc finger protein 191(Zfp191), which is the most highly conserved among the human-mouse SCAN family member orthologues pairs. ...

journal_title：BMC genomics

authors： Li J,Chen X,Gong X,Liu Y,Feng H,Qiu L,Hu Z,Zhang J

更新日期：2009-05-22 00:00:00

abstract：BACKGROUND:A composite biological structure, such as an insect head or abdomen, contains many internal structures with distinct functions. Composite structures are often used in RNA-seq studies, though it is unclear how expression of the same gene in different tissues and structures within the same structure affects th...

journal_title：BMC genomics

authors： Johnson BR,Atallah J,Plachetzki DC

更新日期：2013-08-28 00:00:00

abstract：BACKGROUND:Aging is associated with functional decline of neurons and increased incidence of both neurodegenerative and ocular disease. Photoreceptor neurons in Drosophila melanogaster provide a powerful model for studying the molecular changes involved in functional senescence of neurons since decreased visual behavio...

journal_title：BMC genomics

authors： Hall H,Medina P,Cooper DA,Escobedo SE,Rounds J,Brennan KJ,Vincent C,Miura P,Doerge R,Weake VM

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Propionibacterium acnes and Staphylococcus epidermidis live in close proximity on human skin, and both bacterial species can be isolated from normal and acne vulgaris-affected skin sites. The antagonistic interactions between the two species are poorly understood, as well as the potential significance of bac...

journal_title：BMC genomics

authors： Christensen GJ,Scholz CF,Enghild J,Rohde H,Kilian M,Thürmer A,Brzuszkiewicz E,Lomholt HB,Brüggemann H

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Sugarcane is an economically important crop contributing to about 80% of the world sugar production. Increasing efforts in molecular biological studies have been performed for improving the sugar yield and other relevant important agronomic traits. However, due to sugarcane's complicated genomes, it is still...

journal_title：BMC genomics

authors： Zhang Q,Hu W,Zhu F,Wang L,Yu Q,Ming R,Zhang J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Bloodstream malaria parasites require Ca++ for their development, but the sites and mechanisms of Ca++ utilization are not well understood. We hypothesized that there may be differences in Ca++ uptake or utilization by genetically distinct lines of P. falciparum. These differences, if identified, may provide...

journal_title：BMC genomics

authors： Apolis L,Olivas J,Srinivasan P,Kushwaha AK,Desai SA

更新日期：2019-01-16 00:00:00

abstract：BACKGROUND:Isatis indigotica is a widely used herb for the clinical treatment of colds, fever, and influenza in Traditional Chinese Medicine (TCM). Various structural classes of compounds have been identified as effective ingredients. However, little is known at genetics level about these active metabolites. In the pre...

journal_title：BMC genomics

authors： Chen J,Dong X,Li Q,Zhou X,Gao S,Chen R,Sun L,Zhang L,Chen W

更新日期：2013-12-05 00:00:00

abstract：BACKGROUND:Micro (mi)RNAs are important regulators of plant development. Across plant lineages, Dicer-like 1 (DCL1) proteins process long ds-like structures to produce micro (mi) RNA duplexes in a stepwise manner. These miRNAs are incorporated into Argonaute (AGO) proteins and influence expression of RNAs that have seq...

journal_title：BMC genomics

authors： Jagtap S,Shivaprasad PV

更新日期：2014-12-02 00:00:00