Genomic characterization of ribitol teichoic acid synthesis in Staphylococcus aureus: genes, genomic organization and gene duplication.

abstract：BACKGROUND:Uranium (U) is a naturally occurring radionuclide that has been found in the aquatic environment due to anthropogenic activities. Exposure to U may pose risk to aquatic organisms due to its radiological and chemical toxicity. The present study aimed to characterize the chemical toxicity of U in Atlantic salm...

journal_title：BMC genomics

authors： Song Y,Salbu B,Teien HC,Sørlie Heier L,Rosseland BO,Høgåsen T,Tollefsen KE

更新日期：2014-08-20 00:00:00

abstract：BACKGROUND:Chlamydia pecorum is an important pathogen of domesticated livestock including sheep, cattle and pigs. This pathogen is also a key factor in the decline of the koala in Australia. We sequenced the genomes of three koala C. pecorum strains, isolated from the urogenital tracts and conjunctiva of diseased koala...

journal_title：BMC genomics

authors： Bachmann NL,Fraser TA,Bertelli C,Jelocnik M,Gillett A,Funnell O,Flanagan C,Myers GS,Timms P,Polkinghorne A

更新日期：2014-08-08 00:00:00

abstract：BACKGROUND:Understanding the basis for volatile organic compound (VOC) biosynthesis and regulation is of great importance for the genetic improvement of fruit flavor. Lactones constitute an essential group of fatty acid-derived VOCs conferring peach-like aroma to a number of fruits including peach, plum, pineapple and ...

journal_title：BMC genomics

authors： Sánchez-Sevilla JF,Cruz-Rus E,Valpuesta V,Botella MA,Amaya I

更新日期：2014-04-17 00:00:00

abstract：BACKGROUND:Although primarily known as the site of ribosome subunit production, the nucleolus is involved in numerous and diverse cellular processes. Recent large-scale proteomics projects have identified thousands of human proteins that associate with the nucleolus. However, in most cases, we know neither the fraction...

journal_title：BMC genomics

authors： Scott MS,Boisvert FM,Lamond AI,Barton GJ

更新日期：2011-01-27 00:00:00

abstract：BACKGROUND:The occurrence of liver cancer is higher in males than in females, and the incidence increases during aging. Signaling pathways regulated by retinoid x receptor alpha (RXRalpha) are involved in hepatocellular carcinogenesis. The phenotype of hepatocyte RXRalpha deficient mice is different between genders. To...

journal_title：BMC genomics

authors： Guo M,Gong L,He L,Lehman-McKeeman L,Wan YJ

更新日期：2008-08-28 00:00:00

abstract：BACKGROUND:Trifoliate orange (Poncirus trifoliata (L.) Raf.) is extremely cold hardy after a full acclimation; however the underlying molecular mechanisms underlying this economically valuable trait remain poorly understood. In this study, global transcriptome profiles of trifoliate orange under cold conditions (4 °C) ...

journal_title：BMC genomics

authors： Wang M,Zhang X,Liu JH

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Housekeeping (HK) genes are ubiquitously expressed in all tissue/cell types and constitute a basal transcriptome for the maintenance of basic cellular functions. Partitioning transcriptomes into HK and tissue-specific (TS) genes relatively is fundamental for studying gene expression and cellular differentiat...

journal_title：BMC genomics

authors： Zhu J,He F,Song S,Wang J,Yu J

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Analysis of single nucleotide polymorphisms (SNPs) derived from whole-genome studies allows for rapid evaluation of genome-wide diversity, and genomic epidemiology studies of Plasmodium falciparum provide insights into parasite population structure, gene flow, drug resistance and vaccine development. In area...

journal_title：BMC genomics

authors： Jacob CG,Tan JC,Miller BA,Tan A,Takala-Harrison S,Ferdig MT,Plowe CV

更新日期：2014-08-26 00:00:00

abstract：BACKGROUND:Mapping DNaseI hypersensitive sites is commonly used to identify regulatory regions in the genome. However, currently available methods are either time consuming and laborious, expensive or require large numbers of cells. We aimed to develop a quick and straightforward method for the analysis of DNaseI hyper...

journal_title：BMC genomics

authors： Ohnesorg T,Eggers S,Leonhard WN,Sinclair AH,White SJ

更新日期：2009-09-04 00:00:00

abstract：BACKGROUND:Despite significant efforts from the research community, an extensive portion of the proteins encoded by human genes lack an assigned cellular function. Most metazoan proteins are composed of structural and/or functional domains, of which many appear in multiple proteins. Once a domain is characterized in on...

journal_title：BMC genomics

authors： Kemmer D,Podowski RM,Arenillas D,Lim J,Hodges E,Roth P,Sonnhammer EL,Höög C,Wasserman WW

更新日期：2006-03-13 00:00:00

abstract：BACKGROUND:Host-specific environmental factors induce changes in Bacillus anthracis gene transcription during infection. A global transcription regulator, CodY, plays a pivotal role in regulating central metabolism, biosynthesis, and virulence in B. anthracis. In this study, we utilized RNA-sequencing to assess changes...

journal_title：BMC genomics

authors： Kim SK,Jung KH,Chai YG

更新日期：2016-08-17 00:00:00

abstract：BACKGROUND:Use of genomic tools to characterize wildlife populations has increased in recent years. In the past, genetic characterization has been accomplished with more traditional genetic tools (e.g., microsatellites). The explosion of genomic methods and the subsequent creation of large SNP datasets has led to the p...

journal_title：BMC genomics

authors： Zimmerman SJ,Aldridge CL,Oyler-McCance SJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Lipoxygenases (LOXs), a type of non-haem iron-containing dioxygenase, are ubiquitous enzymes in plants and participate in the formation of fruit aroma which is a very important aspect of fruit quality. Amongst the various aroma volatiles, saturated and unsaturated alcohols and aldehydes provide the character...

journal_title：BMC genomics

authors： Li M,Li L,Dunwell JM,Qiao X,Liu X,Zhang S

更新日期：2014-06-07 00:00:00

abstract：BACKGROUND:Most studies on the paper mulberry are mainly focused on the medicated and pharmacology, fiber quality, leaves feed development, little is known about its mechanism of adaptability to abiotic stress. Physiological measurement, transcriptomics and proteomic analysis were employed to understand its response to...

journal_title：BMC genomics

authors： Peng X,Teng L,Yan X,Zhao M,Shen S

更新日期：2015-11-05 00:00:00

abstract：BACKGROUND:The sRNAs of bacterial pathogens are known to be involved in various cellular roles including environmental adaptation as well as regulation of virulence and pathogenicity. It is expected that sRNAs may also have similar functions for Burkholderia pseudomallei, a soil bacterium that can adapt to diverse envi...

journal_title：BMC genomics

authors： Khoo JS,Chai SF,Mohamed R,Nathan S,Firdaus-Raih M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The freshwater planarian Schmidtea mediterranea is recognised as a valuable model for research into adult stem cells and regeneration. With the advent of the high-throughput sequencing technologies, it has become feasible to undertake detailed transcriptional analysis of its unique stem cell population, the ...

journal_title：BMC genomics

authors： Rodríguez-Esteban G,González-Sastre A,Rojo-Laguna JI,Saló E,Abril JF

更新日期：2015-05-08 00:00:00

abstract：BACKGROUND:Plants respond to low temperature through an intricately coordinated transcriptional network. The CBF/DREB-regulated network of genes has been shown to play a prominent role in freeze-tolerance of Arabidopsis through the process of cold acclimation (CA). Recent evidence also showed that the CBF/DREB regulon ...

journal_title：BMC genomics

authors： Cheng C,Yun KY,Ressom HW,Mohanty B,Bajic VB,Jia Y,Yun SJ,de los Reyes BG

更新日期：2007-06-18 00:00:00

abstract：BACKGROUND:Early maturity is one of the most important and complex agronomic traits in upland cotton (Gossypium hirsutum L). To dissect the genetic architecture of this agronomically important trait, a population consisting of 355 upland cotton germplasm accessions was genotyped using the specific-locus amplified fragm...

journal_title：BMC genomics

authors： Su J,Pang C,Wei H,Li L,Liang B,Wang C,Song M,Wang H,Zhao S,Jia X,Mao G,Huang L,Geng D,Wang C,Fan S,Yu S

更新日期：2016-08-30 00:00:00

abstract：BACKGROUND:Brown planthopper (BPH), Nilaparvata lugens Stål, is one of the most destructive insect pests of rice. The molecular responses of plants to sucking insects resemble responses to pathogen infection. However, the molecular mechanism of BPH-resistance in rice remains unclear. Transcription factors (TF) are up-s...

journal_title：BMC genomics

authors： Wang Y,Guo H,Li H,Zhang H,Miao X

更新日期：2012-12-10 00:00:00

abstract：BACKGROUND:Parasitoid wasps are well-known natural enemies of major agricultural pests and arthropod borne diseases. The parasitoid wasp Macrocentrus cingulum (Hymenoptera: Braconidae) has been widely used to control the notorious insect pests Ostrinia furnacalis (Asian Corn Borer) and O. nubilalis (European corn borer...

journal_title：BMC genomics

authors： Yin C,Li M,Hu J,Lang K,Chen Q,Liu J,Guo D,He K,Dong Y,Luo J,Song Z,Walters JR,Zhang W,Li F,Chen X

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Hemolymph plays key roles in honey bee molecule transport, immune defense, and in monitoring the physiological condition. There is a lack of knowledge regarding how the proteome achieves these biological missions for both the western and eastern honey bees (Apis mellifera and Apis cerana). A time-resolved pr...

journal_title：BMC genomics

authors： Feng M,Ramadan H,Han B,Fang Y,Li J

更新日期：2014-07-05 00:00:00

abstract：BACKGROUND:Matrix attachment regions (MAR) are the sites on genomic DNA that interact with the nuclear matrix. There is increasing evidence for the involvement of MAR in regulation of gene expression. The unsuitability of experimental detection of MAR for genome-wide analyses has led to the development of computational...

journal_title：BMC genomics

authors： Anthony A,Blaxter M

更新日期：2007-11-15 00:00:00

abstract：BACKGROUND:Dimension reduction is a critical issue in the analysis of microarray data, because the high dimensionality of gene expression microarray data set hurts generalization performance of classifiers. It consists of two types of methods, i.e. feature selection and feature extraction. Principle component analysis ...

journal_title：BMC genomics

authors： Li GZ,Bu HL,Yang MQ,Zeng XQ,Yang JY

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:The transcription factors peroxisome proliferator activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα) are key transcriptional regulators of adipocyte differentiation and function. We and others have previously shown that binding sites of these two transcription factors show a high degr...

journal_title：BMC genomics

authors： Schmidt SF,Jørgensen M,Chen Y,Nielsen R,Sandelin A,Mandrup S

更新日期：2011-03-16 00:00:00

abstract：BACKGROUND:Genomic and transcriptomic sequence data are essential tools for tackling ecological problems. Using an approach that combines next-generation sequencing, de novo transcriptome assembly, gene annotation and synthetic gene construction, we identify and cluster the protein families from Favia corals from the n...

journal_title：BMC genomics

authors： Pooyaei Mehr SF,DeSalle R,Kao HT,Narechania A,Han Z,Tchernov D,Pieribone V,Gruber DF

更新日期：2013-08-12 00:00:00

abstract：BACKGROUND:Small untranslated RNAs (sRNAs) seem to be far more abundant than previously believed. The number of sRNAs confirmed in E. coli through various approaches is above 70, with several hundred more sRNA candidate genes under biological validation. Although the total number of sRNAs in any one species is still un...

journal_title：BMC genomics

authors： Ulvé VM,Sevin EW,Chéron A,Barloy-Hubler F

更新日期：2007-12-19 00:00:00

abstract：BACKGROUND:The colonial cyanobacterium Microcystis proliferates in a wide range of freshwater ecosystems and is exposed to changing environmental factors during its life cycle. Microcystis blooms are often toxic, potentially fatal to animals and humans, and may cause environmental problems. There has been little invest...

journal_title：BMC genomics

authors： Frangeul L,Quillardet P,Castets AM,Humbert JF,Matthijs HC,Cortez D,Tolonen A,Zhang CC,Gribaldo S,Kehr JC,Zilliges Y,Ziemert N,Becker S,Talla E,Latifi A,Billault A,Lepelletier A,Dittmann E,Bouchier C,de Marsac NT

更新日期：2008-06-05 00:00:00

abstract：BACKGROUND:Rich in genetic information and cost-effective to genotype, the Insertion-Deletion (InDel) molecular marker system is an important tool for studies in genetics, genomics and for marker-assisted breeding. Advent of next-generation sequencing (NGS) revolutionized the speed and throughput of sequence data gener...

journal_title：BMC genomics

authors： Lv Y,Liu Y,Zhao H

更新日期：2016-04-14 00:00:00

abstract：BACKGROUND:The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an attractive goal. However, large sample numbers are a pre-requisite for the identificati...

journal_title：BMC genomics

authors： Mullen MP,Creevey CJ,Berry DP,McCabe MS,Magee DA,Howard DJ,Killeen AP,Park SD,McGettigan PA,Lucy MC,Machugh DE,Waters SM

更新日期：2012-01-11 00:00:00

abstract：BACKGROUND:Chronic renal disease (CKD) is characterized by complex changes in cell metabolism leading to an increased production of oxygen radicals, that, in turn has been suggested to play a key role in numerous clinical complications of this pathological condition. Several reports have focused on the identification o...

journal_title：BMC genomics

authors： Granata S,Zaza G,Simone S,Villani G,Latorre D,Pontrelli P,Carella M,Schena FP,Grandaliano G,Pertosa G

更新日期：2009-08-21 00:00:00