Foetal 'flat' bile acids reappear during human liver regeneration after surgery.

abstract：BACKGROUND:Hyperlipidemia is a common feature of the nephrotic syndrome (NS). From retrospective studies, it has been suggested that aggressive lipid-lowering with low-density lipoprotein apheresis (LDL-A) may not only improve dyslipidemia but also decrease urinary albumin excretion and increase serum levels of albumin...

journal_title：European journal of clinical investigation

authors： Stenvinkel P,Alvestrand A,Angelin B,Eriksson M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Abnormal erythrocyte Na/Li countertransport is associated with diseases such as essential hypertension and diabetic renal disease. Although it seems unlikely that Na/Li countertransport contributes to any disease process, it may be abnormal because of a change in the cell membrane that is part of the disease...

journal_title：European journal of clinical investigation

authors： Thomas TH,Rutherford PA,Vareesangthip K,Wilkinson R,West IC

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Increased production of chemokines by adipose tissue and defective adipose tissue oxygenation as a result of obesity may induce leucocyte infiltration and subsequent systemic inflammation. OBJECTIVES:1-To determine the relation between the amount of visceral and subcutaneous adipose tissue and the chemokine...

journal_title：European journal of clinical investigation

authors： Faber DR,van der Graaf Y,Westerink J,Kanhai DA,Monajemi H,Visseren FL,SMART study Group.

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:An earlier report described that transgenic mice ubiquitously expressing cryptochrome1 (CRY1) with a mutation in cystein414 (CRY1-AP Tg mice) display diabetes mellitus in addition to anomalous circadian behaviours. This study examined characteristic aspects of symptoms to clarify the diabetes type and pathog...

journal_title：European journal of clinical investigation

authors： Okano S,Hayasaka K,Igarashi M,Iwai H,Togashi Y,Nakajima O

更新日期：2010-11-01 00:00:00

abstract：:There is considerable information to indicate that when there is vessel injury, platelets can play a major role in the development of atherosclerosis and its thromboembolic complications in the non-diabetic population. Diabetes is a disease associated with an increased risk of vascular complications, but the nature of...

journal_title：European journal of clinical investigation

authors： Winocour PD

更新日期：1994-02-01 00:00:00

abstract：:Portal-systemic spill-over of unconjugated ursodeoxycholic acid (UDCA) was assessed in ten healthy subjects, six patients with mild chronic liver disease and eight patients with cirrhosis. Following oral administration of UDCA (1.5 mg/kg body weight), serum concentrations of unconjugated UDCA were measured during 2 h ...

journal_title：European journal of clinical investigation

authors： Miescher G,Paumgartner G,Preisig R

更新日期：1983-12-01 00:00:00

abstract：:Taurodeoxycholic acid increases the incidence of aspirin induced gastric bleeding in rats and in vitro is well bound by Aludrox (aluminium hydroxide) and poorly bound by Maalox (aluminium hydroxide and magnesium hydroxide). We studied the relevance of this binding, as demonstrated in vitro, by observing the effect of ...

journal_title：European journal of clinical investigation

authors： Morgan RJ,Nelson LM,Russell RI,Plevin T

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Profilin-1 is a ubiquitous, actin-binding protein that plays an important role in the regulation of actin polymerization and cytoskeleton remodelling and contributes to vascular dysfunction. We conducted this study to investigate the association of serum profilin-1 levels with fatal and nonfatal CVE in a coh...

journal_title：European journal of clinical investigation

authors： Eroglu E,Unal HU,Guclu A,Kocyigit I,Karaman M,Saglam M,Gezer M,Tas A,Zararsiz G,Eyileten T,Aydin İ,Oguz Y,Gungor O,Yilmaz MI

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Plasmacytoid dendritic cells (pDCs) are multifunctional bone-marrow-derived immune cells that are key players in bridging the innate and adaptive immune systems. Activation of pDCs through toll-like receptor agonists has proven to be an effective treatment for some neoplastic disorders. MATERIALS AND METHOD...

journal_title：European journal of clinical investigation

authors： Lombardi VC,Khaiboullina SF,Rizvanov AA

更新日期：2015-01-01 00:00:00

abstract：:The most well characterized function of pulmonary surfactant is its ability to reduce surface tension at the alveolar air-liquid interface, thereby preventing lung collapse. However, several lines of evidence suggest that surfactant may also have 'non-surfactant' functions: specific components of surfactant (proteins ...

journal_title：European journal of clinical investigation

authors： Pison U,Max M,Neuendank A,Weissbach S,Pietschmann S

更新日期：1994-09-01 00:00:00

abstract：:This study focuses on the role of platelet membrane glycoproteins and platelet-leucocyte adhesion in patients with sepsis and multiple organ failure (MOF). Specifically, the study raises the following issues: (1) the influence of sepsis and MOF on platelet activation as assessed by surface expression of platelet membr...

journal_title：European journal of clinical investigation

authors： Gawaz M,Fateh-Moghadam S,Pilz G,Gurland HJ,Werdan K

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Subclinical hypothyroidism may adversely affect the development of cardiovascular disease (CVD). Less is known about the role of low-normal thyroid function, that is higher thyroid-stimulating hormone and/or lower free thyroxine levels within the euthyroid reference range, in the development of cardio-metabo...

journal_title：European journal of clinical investigation

authors： van Tienhoven-Wind LJ,Dullaart RP

更新日期：2015-05-01 00:00:00

abstract：:The nephrotic syndrome is frequently associated with hyperlipidaemia and hyperfibrinogenaemia, leading to an increased coronary and thrombotic risk, which may be enhanced by high lipoprotein (a) [Lp(a)] concentrations. We followed the quantitative and qualitative pattern of plasma lipoproteins over 18 months in a pati...

journal_title：European journal of clinical investigation

authors： Thiery J,Ivandic B,Bahlmann G,Walli AK,Seidel D

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades angiotensin II to angiotensin 1-7, is also the functional receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) and is highly expressed in the lungs and heart. Patients with SARS also suffered from cardiac disease ...

journal_title：European journal of clinical investigation

authors： Oudit GY,Kassiri Z,Jiang C,Liu PP,Poutanen SM,Penninger JM,Butany J

更新日期：2009-07-01 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease associated with autoimmune disorders. The aetiology is unknown, although it has been suggested that the disease may be related to infectious agents. Previous studies revealed that sera from patients with PBC react against Mycobacterium gordonae. Th...

journal_title：European journal of clinical investigation

authors： Vilagut L,Parés A,Viñas O,Vila J,Jiménez de Anta MT,Rodés J

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Arterial stiffness is an important determinant of cardiovascular risk. It is associated with several cardiovascular risk factors, including hypertension, diabetes and cigarette smoking. However, there are conflicting data about the relationship between arterial stiffness and hypercholesterolemia. Furthermore...

journal_title：European journal of clinical investigation

authors： Riggio S,Mandraffino G,Sardo MA,Iudicello R,Camarda N,Imbalzano E,Alibrandi A,Saitta C,Carerj S,Arrigo T,Saitta A

更新日期：2010-03-01 00:00:00

abstract：:Pulmonary plasma kinetics of endogenous noradrenaline (NA) and tritium labelled L-noradrenaline (3H-NA) was studied in fifteen subjects during pulmonary arterial catheterization. Plasma NA concentration in femoral artery ranged from 0.5 to 8.2 nmol l-1, mean 2.3 nmol l-1, which was not significantly different from tha...

journal_title：European journal of clinical investigation

authors： Henriksen JH,Christensen NJ,Ring-Larsen H

更新日期：1986-10-01 00:00:00

abstract：:We have reported that the disorder of lipoprotein metabolism in hyperalphalipoproteinaemic patients with a deficiency of cholesteryl ester transfer protein (CETP) is characterized by the polydisperse low density lipoprotein (LDL) particles and the accumulation of cholesteryl ester (CE) in high density lipoprotein (HDL...

journal_title：European journal of clinical investigation

authors： Sakai N,Yamashita S,Hirano K,Ishigami M,Arai T,Kobayashi K,Funahashi T,Matsuzawa Y

更新日期：1995-05-01 00:00:00

abstract：INTRODUCTION:Optimizing the approach to older adults with cancer is now a priority given the increasing frequency of new cancer diagnoses that are made in the older population. The comprehensive geriatric assessment (CGA) represents the gold-standard for (1) defining prognosis and ability to withstand cancer treatments...

journal_title：European journal of clinical investigation

authors： Fusco D,Ferrini A,Pasqualetti G,Giannotti C,Cesari M,Laudisio A,Ballestrero A,Scabini S,Odetti PR,Colloca GF,Monzani F,Nencioni A,Antonelli Incalzi R,Monacelli F,Oncogeriatrics Group of the Italian Society of Gerontology, Ger

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Glucocorticosteroids are effective in the treatment of allergic rhinitis, a disease characterized by a variety of symptoms, e.g. rhinorrhea and itching. The time course of symptomatic relief for allergic rhinitis by steroids has not been examined in detail to date, although the onset of steroid action is one...

journal_title：European journal of clinical investigation

authors： Tillmann HC,Stuck BA,Feuring M,Rossol-Haseroth K,Tran BM,Lösel R,Schmidt BM,Hörmann K,Wehling M,Schultz A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The role of the pattern, quantity and site of insulin secretion in the tolerance to a glucose challenge is not fully evaluated in humans because it is difficult to obtain appropriate clinical models. DESIGN:To address this issue, we studied subjects with reduced pancreatic mass (hemipancreatectomized, HEMI)...

journal_title：European journal of clinical investigation

authors： Battezzati A,Zerbi A,Perseghin G,Caumo A,Terruzzi I,Di Carlo V,Luzi L

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:There are close interrelationships between hormones that regulate bone formation and protein biosynthesis. For example, growth hormone and thyroid hormones can influence plasma levels of insulin-like growth factor-I (IGF-I). A patient's status regarding hormones other than IGF-I may thus indirectly modify th...

journal_title：European journal of clinical investigation

authors： Svanberg E,Healey J,Mascarenhas D

更新日期：2001-04-01 00:00:00

abstract：:A significant rise in serum concentrations of aluminum was demonstrated in 23 patients prophylactically treated with the antacid magaldrate, whereas no increase in serum aluminium was observed in another 26 critically ill patients, in whom the use of antacids was avoided. In parallel, urinary excretion rates of alumin...

journal_title：European journal of clinical investigation

authors： Ittel TH,Gladziwa U,Mück W,Sieberth HG

更新日期：1991-02-01 00:00:00

abstract：:Triosephosphate isomerase deficiencies in erythrocytes and leucocytes were discovered in three unrelated families by a heterozygote screening of 3000 blood samples. In addition, a family found by Schroter et al. [not published] was studied. In these four families, only heterozygote carriers were found. In the family d...

journal_title：European journal of clinical investigation

authors： Eber SW,Dünnwald M,Belohradsky BH,Bidlingmaier F,Schievelbein H,Weinmann HM,Krietsch KG

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Clinical practice guidelines recommend regular kidney function monitoring in atrial fibrillation patients on nonvitamin K oral anticoagulants (NOAC); however, information regarding compliance with these recommendations in daily life conditions is scarce. We sought to determine the compliance with kidney func...

journal_title：European journal of clinical investigation

authors： Andreu Cayuelas JM,Caro Martínez C,Flores Blanco PJ,Elvira Ruiz G,Albendin Iglesias H,Cerezo Manchado JJ,Bailen Lorenzo JL,Januzzi JL,García Alberola A,Manzano-Fernández S

更新日期：2018-06-01 00:00:00

abstract：:The formation of metabolites of arachidonic acid by the cyclo-oxygenase and lipoxygenase pathways were determined in human lung tissue, obtained from surgery. In this measurement the chopped tissue was incubated with the calcium ionophore A23187. Formation of metabolites from [1-14C] arachidonic acid was also determin...

journal_title：European journal of clinical investigation

authors： Zijlstra FJ,Naaktgeboren M,Mons H,Vincent JE

更新日期：1987-08-01 00:00:00

abstract：:Efficient fragmentation is the most important prerequisite for successful treatment of gallstones by extracorporeally induced shock waves. No data are available on the amount of energy necessary for stone disintegration and on the threshold energy below which no further fragmentation occurs. We therefore performed an ...

journal_title：European journal of clinical investigation

authors： Neubrand M,Greinwald I,Lobentanzer H,Paumgartner G,Hermeking H,Sauerbruch T

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND/AIMS:Conflicting observations exist concerning the role of nuclear factor kappa B (NFjB) in alcoholic liver disease (ALD) in animal models. To date no studies have examined this aspect in human liver tissue. We here assessed cytokines and toll-like receptors (TLRs) expressions in conjunction with NFkappaB ac...

journal_title：European journal of clinical investigation

authors： Stärkel P,De Saeger C,Strain AJ,Leclercq I,Horsmans Y

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:A more complete assessment of coronary artery disease (CAD) can be performed by coronary computed tomography angiography (CCTA). The aim was to assess the prevalence, distribution and characteristics of coronary artery disease (CAD) and the reclassification of cardiovascular risk by CCTA in an asymptomatic S...

journal_title：European journal of clinical investigation

authors： García-Ortiz L,Barreiro-Perez M,Merchan-Gómez S,Ignacio Recio-Rodriguez J,Sánchez-Aguadero N,Alonso-Dominguez R,Lugones-Sanchez C,Rodríguez-Sanchez E,Sanchez PL,Gómez-Marcos MA,on behalf EVA investigators.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The pathogenesis of atherosclerosis and acute coronary syndromes involves inflammation and immunological mechanisms. We hypothesized that patients with unstable angina may have an imbalance between inflammatory and anti-inflammatory cytokines. DESIGN:Plasma levels of tumour necrosis factor (TNF)alpha and in...

journal_title：European journal of clinical investigation

authors： Waehre T,Halvorsen B,Damås JK,Yndestad A,Brosstad F,Gullestad L,Kjekshus J,Frøland SS,Aukrust P

更新日期：2002-11-01 00:00:00