Abstract:
PURPOSE:This study compared macular capillary leucocyte velocity values measured with a psychophysical blue-field entoptic simulation (BFS) technique and confocal scanning laser Doppler flowmetry. METHODS:A cross-sectional study was performed where macular capillary leucocyte velocity was measured by BFS using an Oculix BFS-2000 V2.1 psychophysical system and by confocal scanning laser Doppler flowmetry using Heidelberg retinal flowmetry (HRF) in 35 type 1 diabetes women during the second trimester. RESULTS:The macular leucocyte velocities measured with BFS correlated significantly with the 50th percentile (r = 0.345, p = 0.042, n = 35, Spearman's non-parametric correlation), the 75th percentile (r = 0.432, p = 0.009) and the 90th percentile (r = 0.373, p = 0.027) of HRF flow values during the second trimester. However, there was no correlation between BFS velocity and the 25th percentile of HRF measurements. CONCLUSIONS:Blue-field simulation is known to be an experimental technique that provides a quantitative measure of flow in the perifoveal capillary network. By contrast, HRF imaging reflects quantitative, multispectral, objective and non-invasive measurements in a two-dimensional projection of a three-dimensional retinal capillary bed. Our study showed that BFS velocity was correlated with HRF values in a group of women with diabetes during pregnancy. The positive correlation between BFS and HRF values suggests that the psychophysical BFS and scanning laser-based HRF measure similar functions in the retina.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Loukovaara S,Harju M,Immonen Idoi
10.1111/j.1755-3768.2008.01303.xsubject
Has Abstractpub_date
2009-08-01 00:00:00pages
506-10issue
5eissn
1755-375Xissn
1755-3768pii
AOS1303journal_volume
87pub_type
杂志文章abstract:PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...
journal_title:Acta ophthalmologica
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abstract:PURPOSE:To examine the movement of air injected in the cornea in simulated deep anterior lamellar keratoplasty (DALK), from the needle tip to the formation of different types of big bubbles (BB) and to ascertain how air travels through the stroma and pre-Descemet's layer [Dua's layer (PDL)] to create a type-1 (air betw...
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abstract::A growing number of studies have reported a link between vascular damage and glaucoma based on optical coherence tomography angiography (OCTA) imaging. This multitude of studies focused on different regions of interest (ROIs) which offers the possibility to draw conclusions on the most discriminative locations to diag...
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pub_type: 杂志文章,评审
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02240.x
更新日期:2012-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2021-01-09 00:00:00
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pub_type: 杂志文章
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01836.x
更新日期:2011-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01367.x
更新日期:2010-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
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更新日期:2014-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02547.x
更新日期:2013-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12691
更新日期:2015-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2011-02-01 00:00:00