Cortical responses to amplitude modulation in guinea pigs and the effects of general anesthesia by pentobarbital.

abstract：:The mechanisms underlying the ototoxicity of ethacrynic acid (EA) are not fully understood. Previous studies have focused on morphologic and enzymatic changes in the stria vascularis. The current experiment shows that one of the earliest effects of EA is ischemia, resulting from impaired blood flow in vessels supplyin...

journal_title：Hearing research

authors： Ding D,McFadden SL,Woo JM,Salvi RJ

更新日期：2002-11-01 00:00:00

abstract：:The effects of hyperosmolar substances on the ultrastructure of the endolymphatic sac were studied in mice. Fifteen minutes after intravenous injection of urea or glycerol, subcellular changes in the endolymphatic sac were observed. These consisted of the occurrence of abundant cytoplasmic granules with a floccular or...

journal_title：Hearing research

authors： Erwall C,Jansson B,Friberg U,Rask-Andersen H

更新日期：1988-09-01 00:00:00

abstract：:Cochlear function was monitored in adult gerbils using distortion product otoacoustic emissions (DPOAE) during intraperitoneal injection of furosemide. All stimulus parameters were varied independently over a wide range, the stimulus frequencies f1 and f2 from 1 to 16 kHz, and the stimulus levels L1 and L2 from 20 to ...

journal_title：Hearing research

authors： Mills DM,Rubel EW

更新日期：1994-06-15 00:00:00

abstract：:This study introduces and evaluates a method for measurement of the longitudinal spread of electrically evoked neural excitation in the cochlea, using the Neural Response Telemetry system (NRT) available with the Nucleus((R)) 24 cochlear implant system. The recently released version of the NRT software (version 3.0) e...

journal_title：Hearing research

authors： Cohen LT,Richardson LM,Saunders E,Cowan RS

更新日期：2003-05-01 00:00:00

abstract：:To rehabilitate profoundly deaf patients who are not suitable for cochlear implants, central auditory prostheses have been implanted. To compare two possible electrode configurations - penetrating and surface ones - electrical stimulation of the cochlear nucleus with both types of arrays was tested on guinea pigs and ...

journal_title：Hearing research

authors： Liu X,McPhee G,Seldon HL,Clark GM

更新日期：1997-12-01 00:00:00

abstract：:Noise trauma, aging, and ototoxicity preferentially damage the outer hair cells of the inner ear, leading to increased hearing thresholds and poorer frequency resolution. Whereas outer hair cells make synaptic connections with less than 10% of afferent auditory nerve fibers (type-II), inner hair cells make connections...

journal_title：Hearing research

authors： Lobarinas E,Salvi R,Ding D

更新日期：2013-08-01 00:00:00

abstract：:The ubiquity of social vocalizations among animals provides the opportunity to identify conserved mechanisms of auditory processing that subserve communication. Identifying auditory coding properties that are shared across vocal communicators will provide insight into how human auditory processing leads to speech perc...

journal_title：Hearing research

authors： Woolley SM,Portfors CV

更新日期：2013-11-01 00:00:00

abstract：:Eye color may be an indicator of inner ear melanin content and has been associated with hearing loss. There is controversy as to whether eye color has an effect on acquired causes of sensorineural hearing loss. This review was conducted to analyze the literature evaluating the relationship between eye color and causes...

journal_title：Hearing research

authors： Mujica-Mota MA,Schermbrucker J,Daniel SJ

更新日期：2015-02-01 00:00:00

abstract：:We review event-related slow firing changes in the auditory cortex and related brain structures. Two types of changes can be distinguished, namely increases and decreases of firing, lasting in the order of seconds. Triggering events can be auditory stimuli, reinforcers, and behavioral responses. Slow firing changes te...

journal_title：Hearing research

authors： Brosch M,Selezneva E,Scheich H

更新日期：2011-01-01 00:00:00

abstract：:A derived response method of acquiring frequency specific auditory evoked potentials that utilizes a pure tone in combination with a toneburst is applied to the measurement of hearing sensitivity in guinea pigs, chinchillas and pocket gophers. Two experiments which demonstrate that thresholds acquired via tone-derived...

journal_title：Hearing research

authors： Hood LJ,Berlin CI,Heffner RS,Morehouse CR,Smith EG,Barlow EK

更新日期：1991-09-01 00:00:00

abstract：:Receptors which bind the neurotrophins NGF, BDNF, NT-3 and NT-4/5 were shown to be present in cochlear and vestibular ganglion cells during development, implying a neurotrophic role for these molecules in the inner ear. We have found by in situ hybridization that cochlear and vestibular sensory epithelial cells expres...

journal_title：Hearing research

authors： Schecterson LC,Bothwell M

更新日期：1994-02-01 00:00:00

abstract：:The human fetus in utero is hypoxic relative to the neonate due to differences between placental and pulmonary oxygenation. Comparable degrees of hypoxia induced in young and adult animals caused an elevation in hearing threshold of a sensorineural nature. It was hypothesised therefore that the human fetus may also ha...

journal_title：Hearing research

authors： Sohmer H,Goitein K,Freeman S

更新日期：1994-02-01 00:00:00

abstract：:Increase in spontaneous neural activity after noise-induced hearing loss has frequently been associated with the phenomenon of tinnitus. Eighteen juvenile and adult cats were exposed for 2 h to a 6 kHz tone with an intensity of 115 dB SPL at the cat's head. Seven non-exposed littermates and seven other normal hearing ...

journal_title：Hearing research

authors： Seki S,Eggermont JJ

更新日期：2003-06-01 00:00:00

abstract：:At the synapse between olivocochlear efferent fibers and outer hair cells (OHCs) of the cochlea, a non-classical ionotropic cholinergic receptor allows Ca(2+) entry into the hair cell, thus activating a Ca(2+)-sensitive K(+) current which hyperpolarizes the cell's membrane. In the mammalian ear, this leads to a reduct...

journal_title：Hearing research

authors： Katz E,Verbitsky M,Rothlin CV,Vetter DE,Heinemann SF,Elgoyhen AB

更新日期：2000-03-01 00:00:00

abstract：:The influence of temporal cues on sequential stream segregation was investigated using five elderly hearing-impaired listeners. In experiment 1, an alternating pattern of A and B tones was used. Each tone was a harmonic complex with a 100-Hz fundamental, with one of three passbands (1250-2500, 1768-3636, or 2500-5000 ...

journal_title：Hearing research

authors： Stainsby TH,Moore BC,Glasberg BR

更新日期：2004-06-01 00:00:00

abstract：:The membrane glycoprotein CTL2/SLC44A2 is expressed by supporting cells in the inner ear and has been identified as a target of antibodies that may induce auto-immune hearing loss. To determine if CTL2/SLC44A2 also has roles in inner ear development and to distinguish between isoform-specific roles, we assessed age-re...

journal_title：Hearing research

authors： Beyer LA,Galano MM,Nair TS,Kommareddi PK,Sha SH,Raphael Y,Carey TE

更新日期：2011-12-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA)-like immunoreactivity in the chick basilar papilla and lagenar macula was studied by using anti-serum against GABA coupled with glutaraldehyde to bovine serum albumin. GABA-like immunoreactivity was localized selectively in the cytoplasm of both tall and short hair cells in the basilar p...

journal_title：Hearing research

authors： Usami S,Igarashi M,Thompson GC

更新日期：1987-01-01 00:00:00

abstract：:Polyclonal antibodies were raised in chickens to the glycosylated forms of the high (H), medium (M) and low (L) molecular mass (MM) mouse tectorins. In the mouse cochlea, all three antibodies stained the tectorial membrane. Antibodies raised to HMM tectorin also stained the hair bundles of both inner and outer hair ce...

journal_title：Hearing research

authors： Killick R,Richardson GP

更新日期：1997-01-01 00:00:00

abstract：:Proteomic analysis of cadaveric formalin-fixed, celloidin-embedded (FFCE) temporal bone tissue has the potential to provide new insights into inner ear disorders. We have developed a liquid chromatography-mass spectrometry (LC-MS) method for tissue sections embedded with celloidin. Q-TOF (Quadrupole-time of flight mas...

journal_title：Hearing research

authors： Aarnisalo AA,Green KM,O'Malley J,Makary C,Adams J,Merchant SN,Evans JE

更新日期：2010-12-01 00:00:00

abstract：:The dose-response ototoxic effects of cisplatin were studied in guinea pigs. Loss of Preyer reflex and suppression of the N1 amplitude occurred in cisplatin-treated animals and was described as dose-related. Drug-induced hair cell damage, as observed with scanning electron microscopy, occurred sporadically throughout ...

journal_title：Hearing research

authors： Barron SE,Daigneault EA

更新日期：1987-01-01 00:00:00

abstract：:Reported are the results of analyses of three-channel Lissajous trajectories (3CLTs) of the auditory brain stem responses (ABRs) in a human subject in whom a focal lesion of the brain stem was caused by stereotactic radiosurgery, the 'gamma knife'. The surgery caused total destruction of the right inferior colliculus....

journal_title：Hearing research

authors： Durrant JD,Martin WH,Hirsch B,Schwegler J

更新日期：1994-01-01 00:00:00

abstract：:When auditory nerve function is lost due to surgical removal of bilateral acoustic tumors in cases of neurofibromatosis type 2, a sense of hearing may be restored by means of an auditory brainstem implant (ABI), which electrically stimulates the cochlear nucleus. Electrically evoked auditory brainstem responses record...

journal_title：Hearing research

authors： Waring MD,Ponton CW,Don M

更新日期：1999-04-01 00:00:00

abstract：:The highly variable benefit of hearing devices is a serious challenge in auditory rehabilitation. Various factors contribute to this phenomenon such as the diversity in ear defects, the different extent of auditory nerve hypoplasia, the age of intervention, and cognitive abilities. Recent analyses indicate that, in ad...

journal_title：Hearing research

authors： Willaredt MA,Ebbers L,Nothwang HG

更新日期：2014-06-01 00:00:00

abstract：:The acoustic distortion product 2f1-f2 was measured in the ear canal of the gray short-tailed opossum. Monodelphis domestica, during stimulation with two pure tone stimuli of the frequencies f1 and f2 (f1 < f2). From 2f1-2f growth functions for different primary frequencies from 4 to 85 kHz, a distortion threshold cur...

journal_title：Hearing research

authors： Faulstich M,Kössl M,Reimer K

更新日期：1996-05-01 00:00:00

abstract：:With the purpose of pinpointing the time of onset of electromotility, outer hair cells (OHCs) from apical and basal turns of the cochleae of postnatal gerbils, ranging in age from 6 to 19 days, were isolated and drawn into a glass microchamber. Length changes evoked by transcellular electrical stimulation were detecte...

journal_title：Hearing research

authors： He DZ,Evans BN,Dallos P

更新日期：1994-07-01 00:00:00

abstract：:We report the results of behavioral studies in cats conducted first, to demonstrate the presence of a monaural mechanism for the enhancement of signal to noise; and then to examine the necessity or sufficiency of the acoustic striae for this mechanism. The results show that cats do indeed have a monaural mechanism for...

journal_title：Hearing research

authors： Masterton RB,Granger EM,Glendenning KK

更新日期：1994-03-01 00:00:00

abstract：:The recovery pattern of threshold shift (TS) and 'dynamic' changes in the stereocilia after exposure to high-level impulse noise in guinea pigs were investigated. 33 albino guinea pigs were exposed to 10 impulse noises at the rate of 1/min. The noise had peak level of 166 dB SPL and a duration of 0.1 ms. Thirteen of t...

journal_title：Hearing research

authors： Gao WY,Ding DL,Zheng XY,Ruan FM

更新日期：1991-08-01 00:00:00

abstract：:Otoacoustic emissions (OAEs) differ between the sexes in humans, rhesus and marmoset monkeys, and sheep. OAEs also are different in a number of special populations of humans. Those basic findings are reviewed and discussed in the context of possible prenatal-androgen effects on the auditory system. A parsimonious expl...

journal_title：Hearing research

authors： McFadden D

更新日期：2009-06-01 00:00:00

abstract：:Admittance at the tympanic membrane was measured in one ear of 73 chicks in 8 age groups between 1 and 150 days post-hatch. Admittance at 7 frequencies (0.66-1.8 kHz) was calculated from measurements of the magnitude and phase angle of sound pressure in front of the tympanic membrane. The results show that admittance ...

journal_title：Hearing research

authors： Saunders JC,Relkin EM,Rosowski JJ,Bahl C

更新日期：1986-01-01 00:00:00

abstract：:The analysis of the auditory scene begins from the moment we hear sounds, making it possible for the infant to distinguish the mother's voice from other sounds in the environment. The purpose of the study was to determine, in two experiments, whether the frequency separation threshold, at which the perception of a mix...

journal_title：Hearing research

authors： Sussman E,Wong R,Horváth J,Winkler I,Wang W

更新日期：2007-03-01 00:00:00