Abstract:
:We report the results of behavioral studies in cats conducted first, to demonstrate the presence of a monaural mechanism for the enhancement of signal to noise; and then to examine the necessity or sufficiency of the acoustic striae for this mechanism. The results show that cats do indeed have a monaural mechanism for enhancing the detection of tones in co-located background noise for noise levels at least as high as 60 dB SPL. The ablation-behavior results show that surgical section of the dorsal (DAS) and most of the intermediate (IAS) striae has no measurable effect on this mechanism. In sharp contrast, even partial section of the trapezoid body results in a profound and permanent deficit and this deficit is not accounted for by hearing loss alone. It is concluded that the ascending and descending fibers in the dorsal and intermediate acoustic striae are neither necessary nor sufficient for enhancing the detection of salient sounds in a noisy environment while the ascending or descending fibers in the ventral acoustic stria are sufficient and probably necessary.
journal_name
Hear Resjournal_title
Hearing researchauthors
Masterton RB,Granger EM,Glendenning KKdoi
10.1016/0378-5955(94)90237-2subject
Has Abstractpub_date
1994-03-01 00:00:00pages
209-22issue
2eissn
0378-5955issn
1878-5891pii
0378-5955(94)90237-2journal_volume
73pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract::Endocochlear potentials (EPs) were investigated in healthy guinea pigs and in those exposed to white noise of 125 dB SPL for 20-80 min. EPs were measured during and after temporary anoxia (3.5 min, denoted as reversible anoxia) and then during continuous anoxia to evaluate noise-induced changes in EP properties. Succi...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(90)90076-2
更新日期:1990-03-01 00:00:00
abstract::Insight into cochlear mechanics can be obtained from semi-analytical and asymptotic solution methods of which the Liouville -Green (LG) method - in another context known as the WKB method - is the most important one. This paper describes the dispersion properties of fluid waves in general terms and develops the LG for...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(84)90101-1
更新日期:1984-02-01 00:00:00
abstract::Hearing aids are a relatively non-invasive means of reducing the negative effects of hearing loss on an individual who does not require a cochlear implant. Music amplified through hearing aids has some interesting characteristics but high fidelity is not typically one of them. This poses a serious problem for the inve...
journal_title:Hearing research
pub_type: 杂志文章,评审
doi:10.1016/j.heares.2013.07.003
更新日期:2014-02-01 00:00:00
abstract::Ototoxicity is a dose-limiting side effect of chemotherapeutic treatment with cisplatin. In a series of experiments on neonatal rat cochlear organotypic cultures, the extent of damage induced by a broad range of cisplatin treatment concentrations was examined. Paradoxically, it was found that hair cell loss was greate...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2011.08.002
更新日期:2011-12-01 00:00:00
abstract::A model for cochlear mechanics is proposed to take account of its two systems, one passive and one active. The classical passive system stimulates the inner hair cells directly at levels above about 40 dB SL. At intensities below about 60 dB an active process, the 'cochlear amplifier' (CA), somehow provides additional...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(83)90136-3
更新日期:1983-01-01 00:00:00
abstract::Sustained vocalizations of vowels [a], [i], and syllable [mə] were collected in twenty normal-hearing individuals. On vocalizations, five conditions of different audio-vocal feedback were introduced separately to the speakers including no masking, wearing supra-aural headphones only, speech-noise masking, high-pass no...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2015.02.005
更新日期:2015-06-01 00:00:00
abstract::Otoconia are biomineral particles of microscopic size essential for perception of gravity and maintenance of balance. Millions of older Americans are affected in their mobility, quality of life and in their health by progressive demineralization of otoconia. Currently, no effective means to prevent or counteract this ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2010.05.019
更新日期:2010-09-01 00:00:00
abstract::Nitric oxide (NO) is a messenger molecule that mediates several physiological functions and pathological processes. Sodium nitroprusside (SNP), a potent vasodilator, when given clinically as an anti-hypertension agent, exerts its function by releasing NO. It was reported recently that SNP causes a loss of auditory ner...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(96)00076-7
更新日期:1996-09-15 00:00:00
abstract::Cave fish have rarely been investigated with regard to their inner ear morphology, hearing abilities, and acoustic communication. Based on a previous study that revealed morphological differences in the saccular otolith between a cave and two surface populations of Poecilia mexicana, we checked for additional differen...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2010.04.001
更新日期:2010-08-01 00:00:00
abstract::This report describes a study that took advantage of the unique reactivity of the patas monkey (Erythrocebus patas) to dihydrostreptomycin-sulfate (DHSM) to investigate the effects of selective outer hair cell (OHC) lesions on psychophysical tuning curves (PTC). Four patas monkeys were trained using operant reinforcem...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(87)90161-4
更新日期:1987-01-01 00:00:00
abstract::We developed a new technique, the isolated in vitro perfused spiral modiolar artery, which allowed the continuous measurement of the vascular diameter and control of the intravascular pressure. An isolated section of the spiral modiolar artery from the gerbil was perfused on one end with a set of concentric pipettes a...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(97)00184-6
更新日期:1998-01-01 00:00:00
abstract::A test of within-channel detection of acoustic temporal fine structure (aTFS) cues is presented. Eight cochlear implant listeners (CI) were asked to discriminate between two Schroeder-phase (SP) complexes using a two-alternative, forced-choice task. Because differences between the acoustic stimuli are primarily constr...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2013.01.004
更新日期:2013-04-01 00:00:00
abstract::The highest spectral ripple density at which the discrimination of ripple glide direction was possible (STRtdir task) was assessed for one-octave wide (narrowband) stimuli with center frequencies of 500, 1000, 2000, and 4000 Hz and for a broadband stimulus. A pink noise lowpass filtered at the lower edge frequency of ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2020.107910
更新日期:2020-04-01 00:00:00
abstract::Several studies have reported an increased incidence of auditory dysfunction among HIV/AIDS patients. We used auditory HEI-OC1 cells in cell viability, flow cytometry and caspases 3/7-activation studies to investigate the potential ototoxicity of fourteen HIV antiretroviral agents: Abacavir, AZT, Delavirdine, Didenosi...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2014.01.005
更新日期:2014-04-01 00:00:00
abstract::The cochlear frequency map is believed to depend on the progressive decrease in partition stiffness from base to apex. Measurements on cochleae from human cadavers by von Békésy (1960) suggested that the elasticity of the partition increases by a factor of 100 from the stapes to the helicotrema. However, conventional ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(98)00133-6
更新日期:1998-10-01 00:00:00
abstract::Recent studies have shown that the vestibular and auditory systems of some species of birds have the capacity to generate sensory hair cells postnatally. We used a traditional technique, 3H-thymidine autoradiography, and a newer method, bromodeoxyuridine immunocytochemistry, to determine whether ongoing proliferation ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(92)90149-h
更新日期:1992-01-01 00:00:00
abstract::The membrane glycoprotein CTL2/SLC44A2 is expressed by supporting cells in the inner ear and has been identified as a target of antibodies that may induce auto-immune hearing loss. To determine if CTL2/SLC44A2 also has roles in inner ear development and to distinguish between isoform-specific roles, we assessed age-re...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2011.09.004
更新日期:2011-12-01 00:00:00
abstract::It is still a matter of debate whether neurons in the higher central nervous system of anurans become progressively more sharply tuned to sounds that have a behavioral importance or that such coding is performed by (small) groups of neurons. The approach we have taken to investigate this matter comprises simultaneous ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(87)90138-9
更新日期:1987-01-01 00:00:00
abstract::The influence of noise exposure on the endothelial transport system in the cochlea was investigated using cationic polyethyleneimine (PEI), since systemically administered PEI passes through the capillary endothelial cell and attaches to basal lamina (BL) anionic sites in the cochlea. Under general anesthesia, all gui...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(01)00397-5
更新日期:2002-02-01 00:00:00
abstract::One of the factors which can affect the amount of temporary threshold shift (TTS) due to acoustic overstimulation is known to be the general metabolic state of the exposed subject. The present study was conducted to elucidate how preexisting intense emotional stress in awake guinea pigs could influence the TTS induced...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(92)90013-d
更新日期:1992-02-01 00:00:00
abstract::A transmission electron microscopy (TEM) study and synaptophysin immunoreactivity analysis of neurons in the human spiral ganglion was performed with particular emphasis on the demonstration of synapses. The study was based on surgical biopsy material obtained during transcochlear meningioma surgery. Vesiculated nerve...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(99)00179-3
更新日期:2000-03-01 00:00:00
abstract::The focus of this study was to gauge the influence of intervening interference on an intensity standard held within auditory working memory through measurement of the just noticeable difference (JND) for intensity. Additionally, the use of interaural phase differences and interaural level differences as spatial cues w...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2008.04.004
更新日期:2008-06-01 00:00:00
abstract::One objective electrophysiological test for deafness involves presenting a brief acoustic stimulus to a subject and measuring the electrical activity evoked in the muscle located just behind the ear (the post-auricular muscle or PAM). Although this electrical response has been known for many years, it has been ignored...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/s0378-5955(99)00159-8
更新日期:1999-12-01 00:00:00
abstract::In mammals, the cochlear sensory epithelium becomes quiescent early during development. After the first postnatal week, there is no cell replacement or proliferation, and severe damage leads to permanent deafness. Supporting cells' trans-differentiation has been suggested as a way to regenerate cochlear hair cells aft...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2018.12.002
更新日期:2019-03-01 00:00:00
abstract::Receptors which bind the neurotrophins NGF, BDNF, NT-3 and NT-4/5 were shown to be present in cochlear and vestibular ganglion cells during development, implying a neurotrophic role for these molecules in the inner ear. We have found by in situ hybridization that cochlear and vestibular sensory epithelial cells expres...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(94)90286-0
更新日期:1994-02-01 00:00:00
abstract::There are three main cues to sound location: the interaural differences in time (ITD) and level (ILD) as well as the monaural spectral shape cues. These cues are generated by the spatial- and frequency-dependent filtering of propagating sound waves by the head and external ears. Although the chinchilla has been used f...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2010.10.007
更新日期:2011-02-01 00:00:00
abstract::The auditory filter may be considered as a weighting function representing frequency selectivity at a particular centre frequency. Its shape can be derived using the power-spectrum model of masking which assumes: (1) in detecting a signal in a masker the observer uses the single auditory filter giving the highest sign...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/0378-5955(87)90050-5
更新日期:1987-01-01 00:00:00
abstract::The auditory system can encode interaural delays in highpass-filtered complex sounds by phase locking to their slowly modulating envelopes. Spectrotemporal analysis of interaurally time-delayed highpass waveforms reveals the presence of a concomitant interaural level cue. The current study systematically investigated ...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2011.01.008
更新日期:2011-07-01 00:00:00
abstract::Mice of the C57BL/6J (B6) inbred strain exhibit genetic progressive sensorineural hearing loss and have been widely used as a model of adult-onset hearing loss and presbycusis. Males and females exhibit similar degrees of hearing loss until about 3 months of age, after which, the loss accelerates in females. This pape...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2008.12.002
更新日期:2009-06-01 00:00:00
abstract::Several studies have shown that treatment with various neurotrophins protects spiral ganglion cells (SGCs) from degeneration in hair-cell deprived cochleas. In most of these studies the neurotrophins are delivered by means of intracochlear delivery methods. Recently, other application methods that might be more suited...
journal_title:Hearing research
pub_type: 杂志文章
doi:10.1016/j.heares.2010.10.003
更新日期:2011-02-01 00:00:00