Abstract：
:The present review concerns the effect on plaque and gingivitis of some antibacterial dentifrices. The difficulties of including cationic agents in conventional dentifrice formulations are briefly discussed. The focus is on 2 recently introduced dentifrices with triclosan as the active ingredient. One aims at providing a slow release reservoir of triclosan in the oral cavity by delivering the substance dissolved in a lipophilic copolymer. 3-month results indicate a modestly improved effect on plaque and gingivitis compared to that of triclosan alone. Long-term studies are needed before conclusions on the clinical relevance can be drawn. The other dentifrice on the market utilises the principle of additive effects by combining triclosan and zinc citrate in the formulation. The combination appears to be more effective against plaque and gingivitis than either compound alone. Studies of up to 1 year duration indicate that the level of oral hygiene and gingival health obtained through an initial period of motivation and oral hygiene instruction can be maintained by regular use of the test dentifrice, while most subjects in the control group returned to pre-experimental levels. Microbiological monitoring indicates no major shifts in plaque ecology nor any development of resistant bacteria, and adverse side-effects have not been observed. It is concluded that the new approaches to chemical plaque control may be beneficial to the population at large, and thus of great clinical relevance.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Gjermo P,Saxton CAdoi
10.1111/j.1600-051x.1991.tb02318.xsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
468-73issue
6eissn
0303-6979issn
1600-051Xjournal_volume
18pub_type
杂志文章,评审abstract：:Serum IgG, IgA and IgM and salivary IgA antibody levels reactive with extracts from Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Eubacterium saburreum and Streptococcus mutans, were measured by enzyme-linked immunosorbent assay in samples from 12 persons before, during and after experimental gingivi...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb00381.x
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVES:This study examined differences in the efficacy of antibiotics against a single strain of three periodontal pathogens grown in an artificial biofilm. METHODS:Single species biofilms were established with artificial saliva and one of the following bacterial strains: Actinobacillus actinomycetemcomitans Y4, S...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.0303-6979.2004.00490.x
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:The regulation of plasminogen activation is a key element in controlling proteolytic events in the extracellular matrix. Our previous studies had demonstrated that in inflamed gingival tissues, tissue-type plasminogen activator (t-PA) is significantly increased in the extracellular matrix of the connective t...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2000.027003149.x
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:The host response to microbial challenge depends on the recruitment of homing leucocytes and may be related to the experience to infectious insults over years. PURPOSE:The aim of this study was to investigate the soft tissue reactions to de novo plaque formation at sites treated with either open flap debrid...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2005.00746.x
更新日期：2005-11-01 00:00:00
abstract：AIM AND BACKGROUND:The position of the most apical inter-dental portion of the alveolar crest is classically used in osseous resective surgery (ORS) to establish the amount of the inter-proximal and buccal/lingual bone resection. Supracrestal fibres connected to the root cementum are always present coronal to the alveo...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2006.01027.x
更新日期：2007-02-01 00:00:00
abstract：AIM:The purpose of this study was to determine inflammatory and epigenetic features following induction of oral and gut dysbiosis in experimental periodontitis in order to examine the interplay between oral and systemic infection. MATERIALS AND METHODS:Periodontitis was induced in 6- to 8-week-old C57BL/6 mice by (a) ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.13151
更新日期：2019-08-01 00:00:00
abstract：AIM:To systematically review the evidence regarding immune senescence in the pathogenesis of periodontitis and dental caries. METHODS:A systematic search of electronic databases utilizing medical subject headings (MeSH terms) supplemented by screening of review articles and other relevant texts was undertaken. RESULT...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,评审
doi：10.1111/jcpe.12675
更新日期：2017-03-01 00:00:00
abstract：:Although root instrumentation has been accepted as the most important cause-related treatment of periodontal diseases, repeated scaling and root planing may over time result in substantive loss of tooth substance and increased sensitivity of the teeth. In an effort to minimize these side effects of therapy, non-root s...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-051x.1999.t01-6-261101.x
更新日期：1999-11-01 00:00:00
abstract：BACKGROUND:Application of recombinant human bone morphogenetic protein-2 (rhBMP-2) has been associated with significant adverse events in craniofacial settings, including swelling and seroma formation. Recent work has demonstrated an inverse relationship between bone formation/maturation and rhBMP-2 dose, frequency/sev...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12270
更新日期：2014-08-01 00:00:00
abstract：AIMS:To evaluate the associations between serum inflammatory biomarkers and periodontal inflammation in subjects with type 1 diabetes mellitus (T1DM). Our hypothesis was that local host responses may be modulated by the serum inflammatory mediators. MATERIAL AND METHODS:Plaque, bleeding on probing and probing pocket d...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2011.01731.x
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to evaluate the effect of a titanium brush and chemical agents following surgical treatment of experimental peri-implantitis. MATERIAL AND METHODS:Six implants were installed in the mandible of eight beagle dogs (unit of analysis) 3 months after tooth extraction. Experimental...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12566
更新日期：2016-08-01 00:00:00
abstract：PRIMARY OBJECTIVE:To evaluate a multicentre clinical trial design for testing powered toothbrushes. SECONDARY OBJECTIVE:To compare the efficacy of a prototype brush head (N2.3) for the Philips Jordan Sensiflex 2000 powered toothbrush (PTB) to that of Braun Oral-B D15 PTB in removing dental plaque MATERIAL AND METHODS...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1034/j.1600-051x.2002.291003.x
更新日期：2002-10-01 00:00:00
abstract：AIM:We want to evaluate the relationship of self-assessed experience and proficiency, manual dexterity and visual-spatial ability with surgical performance. MATERIAL AND METHODS:A total of 26 professionals were included in the study which consisted of four parts: (a) self-assessment by a questionnaire regarding profic...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.13028
更新日期：2019-01-01 00:00:00
abstract：:The efficacy of a new toothbrush filament layout concept (Topix, Peridental, France) was compared to that of a standard vertical-tuft toothbrush. Bacterial and exogenous deposit elimination were used as parameters of efficacy. 30 dental surgery students took part in the study. Plaque index scores were calculated accor...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-051x.1994.tb00724.x
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVES:The aim of this prospective, randomized, controlled clinical study was to compare the effectiveness of a newly developed ultrasonic device to that of scaling and root planing for non-surgical periodontal treatment. MATERIAL AND METHODS:Thirty-eight patients with moderate to advanced chronic periodontal dise...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2004.00496.x
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:A common clinical observation following surgical periodontal therapy with an enamel matrix derivative (Emdogain) is the improved healing of the soft tissues and the limited inflammation of the operated areas. These clinical observations are empirical and difficult to explain. One of the factors influencing t...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2001.281113.x
更新日期：2001-11-01 00:00:00
abstract：:The present investigation was undertaken to evaluate the periodontal response after resolution of inflammation in a situation of established marginal periodontitis, but in the presence of active, continued tooth hypermobility. Periodontitis was induced unilaterally around mandibular second and third bicuspids in 4 squ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1983.tb01286.x
更新日期：1983-07-01 00:00:00
abstract：OBJECTIVES:To explore the subgingival periodontal microflora in a Saudi Arabian population with a special focus on its relationship with various smoking habits. MATERIAL AND METHODS:A total of 198 individuals in the age range 17-60 years were included in the study. 29% were water-pipe smokers, 18% cigarette smokers, 1...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2005.00710.x
更新日期：2005-06-01 00:00:00
abstract：:Little is known about the relationship of aging to periodontal disease. The immune response undergoes aging-related changes resulting in loss of functional capacity. The aim of this study was to investigate the relationship between levels of serum IgG antibodies against suspected periodontal pathogenic microorganisms ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1995.tb01782.x
更新日期：1995-11-01 00:00:00
abstract：:A longitudinal study was conducted on 106 patients attending a dental school and undergoing periodontal treatment, to assess the relationship between some commonly used periodontal indices and the time taken to treat periodontal disease. The data were analysed by assessing the times taken for examination motivation, s...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：
更新日期：1979-06-01 00:00:00
abstract：OBJECTIVE:To compare two sonic toothbrushes in relation to the reversal of experimental gingivitis. MATERIALS AND METHODS:Subjects refrained from brushing mandibular teeth for 21 days. During a 4-week treatment phase, the right or left side of the mouth was brushed with either the Sonic Complete (SC) or Sonicare Elite...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2005.00851.x
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVES:This study was designed to test the efficacy in plaque removal and the potential for gingival abrasion of 3 electric toothbrushes. The established Braun Oral-B 'Ultra' plaque remover (D9), the Philips/Jordan HP 735, and the newly designed Braun Oral-B 3D Plaque Remover (3D). MATERIAL AND METHODS:This study ...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-051x.2001.028006536.x
更新日期：2001-06-01 00:00:00
abstract：AIM:This study analysed the status of DNA methylation in the promoter region of the IL8 gene in oral mucosa cells from healthy, smoker and non-smoker subjects with chronic periodontitis and compared these findings among groups with mRNA levels. MATERIAL AND METHODS:Genomic DNA from epithelial oral cells of 41 healthy ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2009.01446.x
更新日期：2009-09-01 00:00:00
abstract：:Although it is established that the immunosuppressant cyclosporin-A (CsA) and calcium antagonists [Nifedipine (Nif) and Diltiazem (Dz)] can independently induce gingival enlargement, little has been documented on the significance of the salivary CsA levels and the combined effect of CsA and a calcium antagonist upon g...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb00360.x
更新日期：1993-04-01 00:00:00
abstract：:Platelet-derived growth factor (PDGF) and the glucocorticoid dexamethasone combined with a collagen carrier matrix (CM) induced regeneration of the periodontium in monkeys. Regeneration was stringently defined as: (1) new cementum, (2) new supra-crestal bone extending coronally from the residual alveolar interdental s...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1993.tb00403.x
更新日期：1993-08-01 00:00:00
abstract：:The aim of the present investigation was to study the influence of an increased tooth mobility on the resistance offered by the periodontal tissues to probing. 6 beagle dogs were used. At the start of the experiment, the animals had clean teeth and normal gingival and periodontal conditions. In each dog, a device was ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1992.tb02166.x
更新日期：1992-11-01 00:00:00
abstract：PURPOSE:The objective of the present study was to compare inter-proximal fill and papilla height between different embrasures. MATERIAL & METHODS:One hundred and fifty non-smoking consecutive patients (mean age 54, range 32-73; 63 males and 87 females) without periodontal disease were selected in a multidisciplinary p...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12116
更新日期：2013-07-01 00:00:00
abstract：AIMS:Long-term oral chronic inflammatory process is closely related to systemic inflammation, which is a main mechanism involved in non-alcoholic fatty liver disease (NAFLD). Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with NAFLD. This study ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12929
更新日期：2018-08-01 00:00:00
abstract：AIM:To evaluate the association between risk scores generated with a simplified method for periodontal risk assessment (Perio Risk), and tooth loss as well as bone loss during supportive periodontal therapy (SPT). MATERIALS & METHODS:Data related to 109 patients (42 males; mean age: 42.2 ± 10.2 years, range 22-62) enr...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12645
更新日期：2017-01-01 00:00:00
abstract：:The concept of locally delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1998.tb02395.x
更新日期：1998-11-01 00:00:00
