Test positivity cutoff level of a high risk human papillomavirus test could be increased in routine cervical cancer screening.

abstract：:Benign breast disease (BBD) is an established breast cancer (BC) risk factor, but it is unclear whether the magnitude of the association applies to women at familial or genetic risk. This information is needed to improve BC risk assessment in clinical settings. Using the Prospective Family Study Cohort, we used Cox pr...

journal_title：International journal of cancer

authors： Zeinomar N,Phillips KA,Daly MB,Milne RL,Dite GS,MacInnis RJ,Liao Y,Kehm RD,Knight JA,Southey MC,Chung WK,Giles GG,McLachlan SA,Friedlander ML,Weideman PC,Glendon G,Nesci S,kConFab Investigators.,Andrulis IL,Buys SS

更新日期：2019-07-15 00:00:00

abstract：:Laser microdissection (LMD) and microarray were used to identify genes associated with colorectal cancer. Stanniocalcin 2 (STC2) expression and clinicopathological significance in 139 clinical colorectal cancer samples were specifically investigated using real-time quantitative reverse transcription-polymerase chain r...

journal_title：International journal of cancer

authors： Ieta K,Tanaka F,Yokobori T,Kita Y,Haraguchi N,Mimori K,Kato H,Asao T,Inoue H,Kuwano H,Mori M

更新日期：2009-08-15 00:00:00

abstract：:Neoplasms constituted an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of ...

journal_title：International journal of cancer

authors： Jiang S,Li T,Yang Z,Hu W,Yang Y

更新日期：2018-10-01 00:00:00

abstract：:The influence of viremia on hepatic injury in patients infected with hepatitis C virus was examined by analysis of the relationship between alanine aminotransferase activity and the amount of hepatitis C virus RNA in sequential serum samples from I untreated patient with acute hepatitis C and 3 untreated patients with...

journal_title：International journal of cancer

authors： Gunji T,Kato N,Mori S,Ootsuyama Y,Hijikata M,Imawari M,Shimotohno K

更新日期：1992-11-11 00:00:00

abstract：:Three polycyclic hydrocarbons, benz(a)anthracene, 3-methylcholanthrene and 7,12-dimethylbenz(a)anthracene, have been studied in a cell-mediated mutagenesis system using BHK 21 cells to metabolize the hydrocarbons and V-79 cells as targets for detecting induced cytotoxicity and mutation. In large-scale experiments, the...

journal_title：International journal of cancer

authors： Wigley CB,Newbold RF,Amos J,Brookes P

更新日期：1979-05-15 00:00:00

abstract：:Meningioma, the most frequent tumor in the central nervous system, has few recognized risk factors. We explored the role of allergies in a population-based case-control consortium study of meningioma in five geographic areas. We also studied serum levels of a marker of atopic allergy (IgE) in a subset of study partici...

journal_title：International journal of cancer

authors： Wiemels JL,Wrensch M,Sison JD,Zhou M,Bondy M,Calvocoressi L,Black PM,Yu H,Schildkraut JM,Claus EB

更新日期：2011-10-15 00:00:00

abstract：:Adhesion molecules involved in attachment between human pancreatic carcinoma and activated endothelial cells in vitro were investigated. Basal adhesion occurred between 6 pancreatic carcinoma cell lines and unstimulated human umbilical vein endothelial cells (HUVEC), and augmented basal adhesion to activated HUVEC was...

journal_title：International journal of cancer

authors： Iwai K,Ishikura H,Kaji M,Sugiura H,Ishizu A,Takahashi C,Kato H,Tanabe T,Yoshiki T

更新日期：1993-07-30 00:00:00

abstract：:Protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) is an endogenous inhibitor of STAT3 that negatively regulates STAT3 transcriptional activity and cell growth and demonstrates limited expression in the majority of human squamous cell carcinomas of the lung. In this study...

journal_title：International journal of cancer

authors： Dabir S,Kluge A,McColl K,Liu Y,Lam M,Halmos B,Wildey G,Dowlati A

更新日期：2014-03-01 00:00:00

abstract：:Epidemiologic studies indicate that human T-cell lymphotropic virus type I (HTLV-I), the causative agent of most cases of adult T-cell leukemia/lymphoma (ATLL) in Southeast Japan and the Caribbean islands and the probable cause of a progressive neurological disorder often referred to as tropical spastic paraparesis, o...

journal_title：International journal of cancer

authors： Levine PH,Blattner WA,Clark J,Tarone R,Maloney EM,Murphy EM,Gallo RC,Robert-Guroff M,Saxinger WC

更新日期：1988-07-15 00:00:00

abstract：:Somatic cell hybrids have been made between a transformed mouse bladder carcinoma cell line and normal mouse bladder epithelium and mesenchyme. In the epithelial tumour/mesenchyme hybrids the malignant phenotype was expressed dominantly whereas in the carcinoma/normal epithelium hybrids the malignant potential was gre...

journal_title：International journal of cancer

authors： Cowell JK,Franks LM

更新日期：1984-05-15 00:00:00

abstract：:Others have argued that as many as a third of women treated for high-grade cervical intraepithelial neoplasia (CIN) would have developed cervical cancer in the absence of screening and treatment. Under various assumptions and using past data on CIN grade 3 (CIN3) registrations in England and Scotland, we estimate what...

journal_title：International journal of cancer

authors： Sasieni P,Castanon A,Parkin DM

更新日期：2009-01-15 00:00:00

abstract：:Many studies have focused on global hypomethylation or hypermethylation of tumor suppressor genes, but less is known about the impact of promoter hypomethylation of oncogenes. We previously showed that promoter methylation may gradually increase or decrease during the transition from gastric mucosa (GM) to intestinal ...

journal_title：International journal of cancer

authors： Seo EH,Kim HJ,Kim JH,Lim B,Park JL,Kim SY,Lee SI,Jeong HY,Song KS,Kim YS

更新日期：2020-06-15 00:00:00

abstract：:The clinical diagnosis of cervical neoplasia by spectroscopic methods is potentially a reliable, fast and cost-effective alternative to the conventional smear test. However, it is currently limited by significant inter-patient variation in the spectroscopic properties of the cervix. Characterisation of suitable in vit...

journal_title：International journal of cancer

authors： Martin SF,Wood AD,McRobbie MM,Mazilu M,McDonald MP,Samuel ID,Herrington CS

更新日期：2007-05-01 00:00:00

abstract：:Transducer of ErbB-2 (TOB) is a member of the TOB/Btg gene family. A role for TOB in the suppression of human tumorigenesis has been proposed, based on the observations that TOB-knockout mice spontaneously form tumors and TOB expression is lost in human lung and thyroid cancers. However, the role of TOB in human breas...

journal_title：International journal of cancer

authors： O'Malley S,Su H,Zhang T,Ng C,Ge H,Tang CK

更新日期：2009-10-15 00:00:00

abstract：:The interactions which occur between antigenic tumor cells and normal or immune lymphoid cells in a 3-day in vitro culture, have been studied with a murine sarcoma virus (MSV)-induced tumor. The 3H-thymidine incorporation of lymphoma cells growing in suspension, and the radioactive-chromium release of freshly sampled ...

journal_title：International journal of cancer

authors： Senik A,Hebrero FP,Levy JP

更新日期：1975-12-15 00:00:00

abstract：:A series of 42 patients with malignant melanoma treated with BCG adjuvant immunotherapy were studied for sequential changes in cellular immune reactivity to non-specific mitogens. Lymphocyte preparations were made monthly and stored in a viable condition in liquid nitrogen. After 6 months of treatment, all lymphocyte ...

journal_title：International journal of cancer

authors： Golub SH,Forsythe AB,Morton DL

更新日期：1977-01-01 00:00:00

abstract：:Two distinct cell lines (OPM-1 and OPM-2) were established from the peripheral blood of a 56-year-old female myeloma patient at the stage of terminal leukemic evolution associated with loss of cytoplasmic immunoglobulin heavy chain (G lambda----lambda). The lines grew in suspension with a doubling time of 36-42 hr and...

journal_title：International journal of cancer

authors： Katagiri S,Yonezawa T,Kuyama J,Kanayama Y,Nishida K,Abe T,Tamaki T,Ohnishi M,Tarui S

更新日期：1985-08-15 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is rare in most parts of the world, but prevalent in Southern China. Although this disease poses a serious health problem in our population, the genetic alterations that lead to the development of NPC have yet to be defined. In a comparative genomic hybridization (CGH) study on NPC by ou...

journal_title：International journal of cancer

authors： Tsang YS,Lo KW,Leung SF,Choi PH,Fong Y,Lee JC,Huang DP

更新日期：1999-10-29 00:00:00

abstract：:The occurrence of metastasis severely affects prognosis and survival of breast cancer patients. In order to metastasize, breast cancer cells need to cross the basement membrane (BM) tissue boundaries. Matrix metalloproteases (MMPs) are enzymes with proteolytic activity towards extracellular matrix components (ECM) of ...

journal_title：International journal of cancer

authors： Giannelli G,Erriquez R,Fransvea E,Daniele A,Trerotoli P,Schittulli F,Grano M,Quaranta M,Antonaci S

更新日期：2004-05-01 00:00:00

abstract：:Socioeconomic status (SES) is a determinant of outcome in various types of cancer. The aim of this study is to analyze the impact of the SES in Hodgkin's lymphoma (HL). From 2001 to 2005, 194 consecutive patients were prospectively followed in 5 institutions. Patients answered a questionnaire with a set of items used ...

journal_title：International journal of cancer

authors： Soares A,Biasoli I,Scheliga A,Luiz RR,Costa MA,Land M,Romano S,Morais JC,Spector N

更新日期：2007-02-15 00:00:00

abstract：:A human revertant cell line, derived from non-producer human osteosarcoma cells (NP/KHOS) induced by Kirsten murine sarcoma virus, was treated in vitro with various levels of polycyclic aromatic hydrocarbons (3-methylcholanthrene, 7,12-dimethylbenz(alpha)anthracene, and benzo(alpha)pyrene [BP] or dimethyl sulfoxide (c...

journal_title：International journal of cancer

authors： Cho HY,Arnstein P,Rhim JS

更新日期：1978-01-15 00:00:00

abstract：:In order to establish the role of human papillomavirus (HPV) in carcinogenesis of epidermodysplasia verruciformis (EV), the presence, the molecular characteristics and the physical state of HPV DNA in a benign lesion, a primary carcinoma and a metastatic carcinoma developing in the same EV patient were studied and com...

journal_title：International journal of cancer

authors： Yabe Y,Tanimura Y,Sakai A,Hitsumoto T,Nohara N

更新日期：1989-06-15 00:00:00

abstract：:The authors analyzed the HER2 status in early-stage nonrecurrent and recurrent breast cancer groups following breast-conserving treatment. Retrospective analyses of a group of 36 invasive early breast cancer (IBC) patients who developed a local recurrence as a first event and of a random control group of 69 IBC patien...

journal_title：International journal of cancer

authors： López-Guerrero JA,Llombart-Cussac A,Noguera R,Navarro S,Pellin A,Almenar S,Vazquez-Alvadalejo C,Llombart-Bosch A

更新日期：2006-04-01 00:00:00

abstract：:Numerous prospective and retrospective studies have clearly demonstrated a dose-related increased lung cancer risk associated with cigarette smoking, with evidence also for a genetic component to risk. In this study, using the two-stage clonal expansion stochastic model framework, for the first time we investigated th...

journal_title：International journal of cancer

authors： Deng L,Kimmel M,Foy M,Spitz M,Wei Q,Gorlova O

更新日期：2009-05-01 00:00:00

abstract：:We evaluated RS5444, a thiazolidinedione high affinity PPARgamma agonist, for the ability to inhibit colon carcinogenesis in azoxymethane (AOM)-treated mice. In our initial experiment, mice were treated with RS5444 during AOM treatment, and the drug was withdrawn 12 weeks after the last injection of AOM. RS5444 signif...

journal_title：International journal of cancer

authors： Su W,Necela BM,Fujiwara K,Kurakata S,Murray NR,Fields AP,Thompson EA

更新日期：2008-09-01 00:00:00

abstract：:The predictive effect of circulating tumor DNA (ctDNA) in colorectal cancer (CRC) treatment is still highly discussed. The primary objective of our study was to investigate a possible prognostic/predictive value of ctDNA under regorafenib treatment. This prospective multicenter translational biomarker phase II pilot s...

journal_title：International journal of cancer

authors： Unseld M,Belic J,Pierer K,Zhou Q,Moser T,Bauer R,Piringer G,Gerger A,Siebenhüner A,Speicher M,Heitzer E,Prager GW

更新日期：2021-03-15 00:00:00

abstract：:Results of epidemiologic studies of physical activity and ovarian cancer risk are inconsistent. Few have attempted to measure physical activity over the lifetime or in specific age windows, which may better capture etiologically relevant exposures. We examined participation in moderate-to-vigorous recreational physica...

journal_title：International journal of cancer

authors： Grundy A,Ho V,Abrahamowicz M,Parent MÉ,Siemiatycki J,Arseneau J,Gilbert L,Gotlieb WH,Provencher DM,Koushik A

更新日期：2020-04-01 00:00:00

abstract：:Targeted approaches have revealed frequent epigenetic alterations in ovarian cancer, but the scope and relation of these changes to histologic subtype of disease is unclear. Genome-wide methylation and expression data for 14 clear cell carcinoma (CCC), 32 non-CCC and four corresponding normal cell lines were generated...

journal_title：International journal of cancer

authors： Yamaguchi K,Huang Z,Matsumura N,Mandai M,Okamoto T,Baba T,Konishi I,Berchuck A,Murphy SK

更新日期：2014-08-01 00:00:00

abstract：:Cytological screening for cervical cancer is hampered by high false negative rates. Inter-observer reproducibility needs optimizing. The potential of p16(INK4a) as a biomarker for cervical lesions was examined in a study of liquid-based cytology (LBC), HPV DNA testing by MY09/MY11 consensus PCR and type-specific PCRs ...

journal_title：International journal of cancer

authors： Sahebali S,Depuydt CE,Segers K,Moeneclaey LM,Vereecken AJ,Van Marck E,Bogers JJ

更新日期：2004-03-01 00:00:00

abstract：:Co-injection of fibroblasts with human epithelial breast-tumor MCF7 cells in the presence of Matrigel enhances tumor growth in nude mice. While most of the matrix metalloproteinases (MMPs) have been shown to be produced by stromal cells, tumor cells such as MCF7 cells are unable to produce MMPs. We therefore, hypothes...

journal_title：International journal of cancer

authors： Noël A,Hajitou A,L'Hoir C,Maquoi E,Baramova E,Lewalle JM,Remacle A,Kebers F,Brown P,Calberg-Bacq CM,Foidart JM

更新日期：1998-04-13 00:00:00