Deciphering the roles of FOXO1 in human neoplasms.

Abstract:

:Neoplasms constituted an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of FOXO1 in neoplasms. This article may serve as a guide for future research and identify FOXO1 as a potent therapeutic target in neoplasms.

journal_name

Int J Cancer

authors

Jiang S,Li T,Yang Z,Hu W,Yang Y

doi

10.1002/ijc.31338

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

1560-1568

issue

7

eissn

0020-7136

issn

1097-0215

journal_volume

143

pub_type

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