Can stereotactic fractionated radiation therapy become the standard of care for early stage non-small cell lung carcinoma.

Abstract:

:Management of early stages non-small cell lung carcinoma has traditionally been surgery with radiation selected for medically inoperable patients. Recent emergence of stereotactic body radiation therapy allows for delivery of high radiation dose to the tumor while sparing normal lungs. This reviews compares loco-regional control, survival and complications rates between these two treatment modalities. Literature search identifies studies with stereotactic body radiation therapy and surgery for early stages non-small cell lung cancer. Effectiveness and toxicity of these two modalities was assessed. Stereotactic body radiation therapy is associated with minimal morbidity and provides comparable local control and survival in patients with multiple co-morbidities factors. Stereotactic body radiation therapy may become standard of care for operable early stages non-small cell lung cancer.

journal_name

Cancer Treat Rev

journal_title

Cancer treatment reviews

authors

Nguyen NP,Garland L,Welsh J,Hamilton R,Cohen D,Vinh-Hung V

doi

10.1016/j.ctrv.2008.06.001

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

719-27

issue

8

eissn

0305-7372

issn

1532-1967

pii

S0305-7372(08)00236-3

journal_volume

34

pub_type

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