Abstract：
BACKGROUND:Only a few epidemiological studies on hand eczema (HE) in the metalworking industry have been conducted, and no study has attempted a long-term follow-up. OBJECTIVES:In the Prospective Audi Cohort (PACO) II follow-up study, we aimed to estimate burden and prognosis of HE in a car industry setting (follow-up > 10 years). PATIENTS/METHODS:Eligible participants were individuals who had been examined in the original PACO study (1990-1998) and had been followed through until the end of their apprenticeship (n = 1909). Participants were interviewed and underwent dermatological examination. An exposure assessment was carried out according to a pre-defined algorithm. RESULTS:The follow-up rate was 78.3% (1494/1909). Mean follow-up time was 13.3 [standard deviation 1.3] years. The period prevalence of HE in the follow-up period was 21.0% [95% confidence interval (CI) 19.0-23.1%], yielding a cumulative incidence of 29.3% (95% CI 26.9-31.6%) in the entire study period. HE persisted after the end of apprenticeship in 40.0% (95% CI 33.3-46.7%) of subjects who had had HE during apprenticeship (n = 205). 18.0% (95% CI 15.9-20.1%) developed HE in the follow-up period (n = 1289). CONCLUSIONS:Around 30% of subjects were affected by HE at least once during the study period. HE persisted in 40% of the participants affected during apprenticeship.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Apfelbacher CJ,Radulescu M,Diepgen TL,Funke Udoi
10.1111/j.1600-0536.2008.01329.xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
322-9issue
6eissn
0105-1873issn
1600-0536pii
COD1329journal_volume
58pub_type
杂志文章abstract：:Risk factors for cement eczema were studied among workers employed in the Danish construction industry. 2 cohorts exposed to cement containing different concentrations of water-soluble chromate were examined. A statistically significant decrease in the number of workers with allergic cement eczema was found in the coh...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1991.tb01793.x
更新日期：1991-08-01 00:00:00
abstract：:Occupational skin disease is one of the most common occupational diseases. The hand is the most frequent site of involvement in occupational skin disease. We interviewed and examined patients seen in the Contact Dermatitis Clinic of the National Taiwan University Medical Center, a tertiary referral center in Taipei Ci...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1995.tb02077.x
更新日期：1995-12-01 00:00:00
abstract：BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1111/cod.12124
更新日期：2014-02-01 00:00:00
abstract：:Investigations on light reactions in a patient with vitiligo are presented. The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1983.tb04429.x
更新日期：1983-09-01 00:00:00
abstract：:A predictive study comparing the sensitizing potentials of some topical antimicrobials, using a modified Beuhler's technique, showed that over-the-counter (OTC) antimicrobials were more sensitizing than prescribed topical antibiotics. Among OTC antimicrobials, proflavine was the most potent sensitizer (4/10 guinea pig...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1989.tb04730.x
更新日期：1989-09-01 00:00:00
abstract：:We report a case of hypertrophic allergic contact dermatitis probably due to p-phenylenediamine (PPDA) in a 26-year-old female, which developed at the sites of application of a black hair dye to the skin. Histological examination revealed an eczematous process. The lesions subsided completely except for leukoderma tha...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1994.tb01958.x
更新日期：1994-09-01 00:00:00
abstract：:Contact allergy to the industrial preservative group of Biobans has been reported in individual cases. We have performed a prospective study on 408 metalworkers who were tested with 6 different Biobans, formaldehyde and 5 other preservatives. Furthermore, retesting was performed after a time interval of 6 months to 4 ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2002.470106.x
更新日期：2002-07-01 00:00:00
abstract：BACKGROUND:Preservatives such as formaldehyde and formaldehyde-releasers are common causes of contact allergy. OBJECTIVES:To examine trends in contact allergy to formaldehyde and formaldehyde-releasers in patch tested patients in Denmark over a 10-year period (2007-2016), and to investigate relevant sources of formald...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.13052
更新日期：2018-11-01 00:00:00
abstract：:The introduction of the euro has revived interest in the risk of nickel allergy due to the handling of coins. In the present work, the transfer of metallic contamination during the manipulation of coins is examined by means of leaching experiments and manipulation tests. It is shown that pre-existing metallic species ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2003.00028.x
更新日期：2003-04-01 00:00:00
abstract：:Severe allergic contact dermatitis from a paint mildewcide, 2-n-octyl-4-isothiazolin-3-one, developed in a worker formulating latex paints within a paint manufacturing company, Guinea pig maximization testing demonstrated this to be a moderate sensitizer. Further cases of allergic contact dermatitis may be encountered...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1983.tb04473.x
更新日期：1983-11-01 00:00:00
abstract：:Contact allergy to dental allergens is a well-studied subject, more so among dental professionals than dental patients. 1632 subjects had been patch tested to either the dental patient series or dental personnel series at the department of Occupational and Environmental Dermatology, Malmö, Sweden. Positive patch tests...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2006.00922.x
更新日期：2006-10-01 00:00:00
abstract：:The Nyloprint process is becoming more frequently used in Great Britain. We report a case of contact dermatitis in a 60-year-old man who was employed in the production of Nyloprint formes. The process is described in detail. Patch tests showed him to be very sensitive to an acrylamide derivative, which is used as a mo...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1976.tb03013.x
更新日期：1976-06-01 00:00:00
abstract：:A case is reported of a foam rubber carrier with pustular lesions on the arms, wrists, thighs and trunk. Scratch and patch testing with the foam rubber components was negative. Animal testing revealed sodium hexafluorosilicate (Na2SiF6), one of the ingredients of the foam rubber, to be a pustulogen on previously damag...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1985.tb01038.x
更新日期：1985-01-01 00:00:00
abstract：:In a multicentre study of the German Contact Dermatitis Research Group, sodium lauryl sulfate (SLS) 0.25% and 0.5% aq. has been added to routine allergen patch tests to assess its properties as a convenient diagnostic indicator of individual susceptibility to irritation at the time of patch testing. Previous studies i...
journal_title：Contact dermatitis
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.0105-1873.2004.00458.x
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Chromium (Cr) is a common skin sensitizer. The use of Cr(VI) in leather is restricted in the EU, but that of Cr(III) is not. OBJECTIVES:To assess whether prolonged exposure to Cr-tanned leather with mainly Cr(III) release may elicit allergic contact dermatitis in Cr-allergic individuals. METHOD:Ten Cr-alle...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.12946
更新日期：2018-05-01 00:00:00
abstract：:Bibliographic sources for the complex subject of aroma chemicals are reviewed. The references are not comprehensive but are those which we found to be of value in finding out some of the opportunities for contact with a sensitizing chemical compound, cinnamic aldehyde. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1975.tb05310.x
更新日期：1975-01-01 00:00:00
abstract：:Serious adverse skin reactions to permanent hair dyes and temporary black tattoos have been reported. As temporary tattoos have become fashionable among adolescents, the risk profile for p-phenylenediamine (PPD) sensitization of the population has changed simultaneously with an increasing use of hair dyes in this age ...
journal_title：Contact dermatitis
pub_type： 杂志文章,多中心研究
doi：10.1111/j.0105-1873.2006.00746.x
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Red tattoos are prone to allergic reactions. The identity of the allergen(s) is mostly unknown. OBJECTIVES:Chemical analysis of human skin biopsies from chronic allergic reactions in red tattoos to identify culprit pigment(s) and metals. MATERIAL AND METHODS:One hundred four dermatome biopsies were analyze...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/cod.13423
更新日期：2020-02-01 00:00:00
abstract：:Bullous dermatitis, which resolved leaving hyperpigmentation and which was clinically consistent with phytophotodermatitis , affected the skin of the neck of 2 individuals who wore Hawaiian leis (as neck garlands ) made of the fruits of Pelea anisata . In a Daniels culture plate system portions of the fruits showed ph...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1984.tb00104.x
更新日期：1984-04-01 00:00:00
abstract：:In some patients with atopic dermatitis (AD), delayed-type allergy to aeroallergens, such as house dust mite, can be demonstrated by patch testing. Positive patch tests can be expected only in patients with AD and, in them, only to aeroallergens to which type 1 reactions have also been demonstrated. In an as yet unkno...
journal_title：Contact dermatitis
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0536.1989.tb03197.x
更新日期：1989-10-01 00:00:00
abstract：:Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1997.tb00393.x
更新日期：1997-03-01 00:00:00
abstract：:A patient was found to have a delayed positive patch test to hydrocortisone on multiple testing. This proved to be due to a photoallergy with an action spectrum in the UV-A range. The patient coincidently had a polymorphous light eruption in the UV-B range. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1978.tb03845.x
更新日期：1978-12-01 00:00:00
abstract：:Interleukin-12 (IL-12) has previously been suggested as playing a major rôle in the activation of cytotoxic lymphocytes. Recent reports indicate that cytotoxic CD8+ cells are critically involved in the elicitation phase of contact hypersensitivity reactions. In this study, the in situ expression of IL-12 was investiga...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1034/j.1600-0536.2000.042001018.x
更新日期：2000-01-01 00:00:00
abstract：:Despite the frequency of irritant contact dermatitis, very little is known about the duration of barrier function impairment following cumulative irritant contact dermatitis. We studied post-irritation irritant reactivity by assessing the response to SLS irritation in previously irritated sites. Cumulative irritant co...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1994.tb00725.x
更新日期：1994-01-01 00:00:00
abstract：:A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1979.tb04860.x
更新日期：1979-07-01 00:00:00
abstract：:The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1979.tb04910.x
更新日期：1979-12-01 00:00:00
abstract：BACKGROUND:Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) has been one of the most frequent sensitizers since the 1980s. In 2005, the use of MI alone was approved for the preservation of cosmetic and household products in the EU. Before that, MI was used in industrial products, and the first cases of isolat...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.2010.01774.x
更新日期：2010-09-01 00:00:00
abstract：:Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to chromium from leather products includes both Cr(III) and Cr(VI). We have determined and compared the minimum elicitation threshold (MET) concentration for Cr(III) and Cr(VI) in Cr(VI)-sensitive patients. In addition,...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2003.0230.x
更新日期：2003-10-01 00:00:00
abstract：:A 30-year-old male developed asthma and pruritus after using an insecticidal spray (Pyrex). The same symptoms appeared with an alcoholic skin disinfectant (M-sprit) and other spirituous preparations denaturated with denatonium benzoate (Bitrex). An open epicutaneous test (20 min) showed wheal and erythema to Pyrex, M-...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.1600-0536.1980.tb05568.x
更新日期：1980-12-01 00:00:00
abstract：:High frequencies of contact allergy to fragrance ingredients have been reported in recent years. Only approximately 70-80% are detected by fragrance allergens in the standard patch test series. This investigation compares the patch test reactions to fine fragrances with reactions to fragrance mix (FM), balsam of Peru ...
journal_title：Contact dermatitis
pub_type： 杂志文章
doi：10.1111/j.0105-1873.2003.0264.x
更新日期：2003-12-01 00:00:00
