Abstract:
:Water homeostasis of the epidermis is important for the appearance and physical properties of the skin, as well as for water balance in the body. It depends on several factors, e.g. barrier quality, uptake of water into the epidermis, concentration of water-retaining humectants, and external humidity. Aquaporins (AQPs) are pores in the plasmamembranes of cells. Monomeric AQPs form barrel-like structures that are primarily water selective, some AQPs also transport glycerol and possibly other small solutes. In the epidermis, AQP3 is the predominant AQP. It is localized mainly in basal but also in suprabasal layers of the epidermis and is permeable for water as well as for glycerol, a humectant. Mice deficient in AQP3 exhibit reduced stratum corneum (SC) hydration and impaired SC barrier recovery after SC removal. In skin diseases associated with elevated transepidermal water loss (TEWL) and reduced SC hydration, altered expression of AQP3 was shown. Tight junctions (TJ) are cell-cell junctions, which play a central role in sealing the intercellular space of cell sheets and thereby establishing a paracellular barrier. Within the TJ, pores are postulated to exist, which allow the controlled diffusion of water and solutes via the paracellular pathway. In the epidermis, TJ structures were demonstrated in the stratum granulosum whereas TJ proteins were found in all viable layers. Mice which overexpress or are deficient of key-proteins of TJ die soon after birth because of a tremendous TEWL. In various skin diseases that are accompanied by elevated TEWL and reduced skin hydration, staining patterns of TJ proteins are altered. This review will summarize our current knowledge of the involvement of AQPs and TJ in the water homeostasis of the epidermis.
journal_name
Int J Cosmet Scijournal_title
International journal of cosmetic scienceauthors
Brandner JMdoi
10.1111/j.1468-2494.2007.00402.xsubject
Has Abstractpub_date
2007-12-01 00:00:00pages
413-22issue
6eissn
0142-5463issn
1468-2494pii
ICS402journal_volume
29pub_type
杂志文章abstract::Synopsis A technique was developed to evaluate the relative slip of ten test talcs and two control talcs (one with known good slip and one with known poor slip properties). The study was conducted under double-blind conditions with a naive panel of 19 subjects, who with minimal training ranked the 12 talcs. The rankin...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1992.tb00041.x
更新日期:1992-04-01 00:00:00
abstract::Synopsis The mechanism of colour change during the pigment dispersion process and during powder application to the skin surface was studied by examining the colour extension properties of Yellow. Red, and Black iron oxides in white powder bases. A new measure for the evaluation of the degree of colour extension was de...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1985.tb00391.x
更新日期:1985-02-01 00:00:00
abstract:OBJECTIVE:We investigated the association of psychosocial problems, menopausal symptoms such as hot flushes, and trends of smoking and use of cosmetics in our previous study. In this follow-up study, we researched psychiatric disorders and psychosocial problems in menopausal women. METHODS:We designed a cohort study w...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12081
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To understand the drivers of body skin discomfort and to validate a new index to assess its severity. This index should be sensitive enough to capture changes in response to treatment. METHODS:Previous consumer studies suggested seven potential main dimensions behind skin discomfort. Four of them refer to se...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12490
更新日期:2018-10-01 00:00:00
abstract::The oxidative stress element of unhealthy scalp leads to compromised pre-emergent hair formation and poorly formed hair as it grows. Only cosmetic solutions can minimize the impact of unhealthy hair and to achieve healthy looking and feeling hair, the scalp health must be normalized first. The objectives of this resea...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/ics.12289
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Facial attractiveness has been reported to be influenced by visual features such as facial shape and the colour and texture of the skin. However, no empirical studies have examined the effects of facial skin radiance on facial attractiveness. The present study investigated whether types of skin reflection (i....
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12673
更新日期:2020-11-20 00:00:00
abstract::Fading of artificial hair colour has been investigated by simulating actual usage conditions through exposure to artificial radiation in a weatherometer, with 0.35 mW (m(2)nm)(-1) at 340 nm, for 16-48 h, and by periodical washing. Hair colour was produced by using commercial two-part, permanent hair dyes with light au...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00314_3.x
更新日期:2006-06-01 00:00:00
abstract::Synopsis In the last few years a lot of attention has been paid to the development of the in vitro models which would substitute for animals in cutaneous irritancy studies. These models explore either organ or explant cultures using freshly excised skin or serial cultures of isolated skin cells (epidermal keratinocyte...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1992.tb00058.x
更新日期:1992-12-01 00:00:00
abstract::It is well established that the evaporation of sweat from the human body surface is the main mechanism by which heat balance is maintained following a rise in body core temperature. Since the introduction of the first brand name antiperspirant in the United States during the early 1900s, antiperspirant products design...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2003.00184.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:A comprehensive methodology for the simultaneous determination of 15 multiclass organic UV filters in sunscreen cosmetics was developed using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). METHODS:Sunscreen cosmetics of various matrices,...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12387
更新日期:2017-08-01 00:00:00
abstract::Summary A new instrument has been developed which enables simultaneous determinations of the static and dynamic moduli of elasticity of the stratum corneum to be made. A systematic study of these mechanical parameters for various samples of human SC demonstrates the advantages of the dynamic measurement of the modulus...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1982.tb00321.x
更新日期:1982-12-01 00:00:00
abstract::Many cosmetics contain keratolytic hydroxy acids to correct the effects of photoageing on human skin. Although methods exist for quantifying the alpha-hydroxy acid, glycolic acid in aqueous media, accurate methods for quantification in mixed hydrophobic and aqueous cosmetic creams and lotions are lacking. Glycolic aci...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2002.00128.x
更新日期:2002-04-01 00:00:00
abstract::Singlet-oxygen is a non-radical reactive oxygen species believed to play a major role in many photooxidation processes in connection with diverse photo-biological processes such as skin ageing or photocarcinogenesis. Dimethylmethoxy chromanol (3,4-dihydro-6-hydroxy-2,2-dimethyl-7-methoxy-1(2H)-benzopyran) is a potent ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12039
更新日期:2013-06-01 00:00:00
abstract::The causative substances for axillary osmidrosis, which are often found in apocrine sweat, are the decomposed/denatured products of short-chain fatty acid and other biological metabolite compounds produced by axillary-resident bacteria. Conventional underarm deodorants suppress the process of odour production mostly b...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00322.x
更新日期:2006-08-01 00:00:00
abstract::Synopsis This paper reports preliminary results of a study carried out on liquid crystal emulsions added to three different inorganic sunscreens: ultrafine zinc oxide, ultrafine titanium dioxide (inorganic-treated) and ultrafine titanium dioxide (organic-treated hydrophobically). The aim of the work was to investigate...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1994.tb00101.x
更新日期:1994-12-01 00:00:00
abstract::Scars are well known to have a stratum corneum that is malfunctional. Increases in transepidermal water loss and decreases in stratum corneum capacitance and conductance have been reported. Occlusion therapy is a well-known route to improving the signs and symptoms of scarring. Until recently that has been assumed to ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2012.751.x
更新日期:2012-09-23 00:00:00
abstract:OBJECTIVE:Development of an international harmonized in vitro method for sun protection factor (SPF) assessment is currently in progress because of the lack of both reproducibility and accuracy in the current methodology. The aim of this article was to focus on the principle and mathematical aspects (Part I) of a new a...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/ics.12226
更新日期:2015-12-01 00:00:00
abstract::Synopsis A rapid method has been developed in order to compare the photostability of several sunscreen agents incorporated in the same type of emulsion. Thin films of the different preparations were spread on quartz plates and irradiated with a solar simulator. Differences in energy distribution according to wavelengt...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1988.tb00002.x
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:Lipsticks and lip care products may contain saturated hydrocarbons which either stem from mineral oil saturated hydrocarbons (MOSH) or are synthetic, that is polyolefin oligomeric saturated hydrocarbons (POSH). Some of these hydrocarbons are strongly accumulated and form granulomas in human tissues, which pro...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12276
更新日期:2016-04-01 00:00:00
abstract::Synopsis In this study a compact, hand-held, solid state erythema meter using light emitting diodes is described. This device has been constructed and used to compare with visual assessments of ultraviolet radiation in human subjects. A statistically significant correlation was obtained between erythema index and visu...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1990.tb00521.x
更新日期:1990-04-01 00:00:00
abstract::Several treatments for skin whitening are available today, but few of them are completely adequate, especially owing to the carcinogenic potential attributed to classical drugs like hydroquinone, arbutin and kojic acid. To provide an alternative and safer technology for whitening, we developed two botanical compounds ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2012.00736.x
更新日期:2012-10-01 00:00:00
abstract::Synopsis The purpose of this work was to compare the evolution of three multiple emulsions (ME) by different controls. The series of water-in-oil-in-water (W/O/W) multiple emulsions were elaborated and controlled by both the usual analyses which permitted the classification of the multiple emulsions with respect to th...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1993.tb00069.x
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVE:The aim of this work was to investigate an alternative hair-dyeing method with vegetable colourants as the tannins, as well as the impact of pre-treatment as the bleaching process. METHODS:Untreated, 1, 2 and 3 times bleached hair tresses that were dyed with tannins in combination with metal salts were chara...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/ics.12624
更新日期:2020-08-01 00:00:00
abstract::Summary The authors studied the combination of Kathon(R) CG and Germall(R) II (0.1%-0.1%) in hydrophilic creams. Their objective was to find an alternative to the use of parabens. Kathon(R) CG was chosen due to its antimicrobial effectiveness and its broad spectrum of activity. It must be indicated, however, that it h...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1987.tb00463.x
更新日期:1987-04-01 00:00:00
abstract::Body odours are generated from dead skin cells and secreted materials, such as sweat and sebum, through the metabolism of microorganisms living on the skin. Volatile steroids, key compounds in body odours, are also generated through the metabolism of microorganisms. These volatile steroids strengthen the intensity of ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.2006.00297.x
更新日期:2006-02-01 00:00:00
abstract::Synopsis The principles on which stability tests are based are reviewed. The need to differentiate between product stability and product-container compatibility is emphasized. Recognition of this distinction is fundamental to the efficient organisation and execution of stability tests. Attention is also drawn to the d...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1985.tb00423.x
更新日期:1985-12-01 00:00:00
abstract:OBJECTIVES:Hyaluronan (HA), an important constituent of extracellular matrix in the skin, has many biological activities such as hydration that contributes to firmness and bounciness of the skin. We have reported that reduction in HA in the papillary dermis and over-expression of HYBID (HYaluronan Binding protein Invol...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,随机对照试验
doi:10.1111/ics.12505
更新日期:2019-02-01 00:00:00
abstract::Solid lipid nanoparticle (SLN) was regarded as new topical delivery systems for pharmaceutical and cosmetic active ingredients. The purpose of this study is to develop carrier systems for organic and inorganic sunscreens based on a matrix composed of carnauba wax and decyl oleate. Formulae (F1-F7) were prepared using ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2010.00598.x
更新日期:2011-02-01 00:00:00
abstract::Synopsis This study has evaluated the ultraviolet light transmission characteristics of human stratum corneum at the single cell level using a low light level video microscope to measure the mean percentage transmission of light at different wavelengths and the variation in transmission across the stratum corneum. Str...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1989.tb00508.x
更新日期:1989-08-01 00:00:00
abstract::The assessment of many aspects of the structure and biological dynamics of the stratum corneum can be conducted using calibrated stripping with adhesive-coated discs (SACD). Squamometry entails staining SACD samples with a toluidine blue-basic fuschsin ethanol-based solution and reading the colorimetric variable Chrom...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00