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Time domain parameters can be estimated with less statistical error than frequency domain parameters in the analysis of heart rate variability.

Abstract：

INTRODUCTION:Measures of heart rate variability (HRV) can be divided in time domain and frequency domain parameters. It is frequently ignored that estimation of frequency-domain parameters is a 2-step procedure where statistical error from the first step (spectral estimation) is neglected in subsequent analyses. METHODS:We performed a simulation study to quantify the statistical error by using frequency domain instead of time domain parameters. We generated tachograms from a stationary AR(1) process for a wide range of parameters and compared the resulting estimation error (in terms of precision and variability) for the standard deviation of normal RR intervals (SDNN) and low frequency (LF), high frequency (HF), and LF/HF power. RESULTS:Estimation of frequency domain parameters is associated with (up to 10-fold) increased variability, as compared with the SDNN. Moreover, the SDNN has higher precision. CONCLUSION:Frequency domain parameters should be applied in HRV analysis only if important physiological reasons suggest their use. If used, frequency domain parameters should be interpreted with caution, taking into account the statistical weaknesses of spectral estimation.

journal_name

J Electrocardiol

journal_title

Journal of electrocardiology

authors

Kuss O,Schumann B,Kluttig A,Greiser KH,Haerting J

doi

10.1016/j.jelectrocard.2008.02.014

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

287-91

issue

4

eissn

0022-0736

issn

1532-8430

pii

S0022-0736(08)00062-9

journal_volume

41

pub_type

杂志文章

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