Abstract:
:The electrophysiologic actions of epinephrine (10(-9) M, 10(-8) M, and 10(-7) M) were evaluated in canine Purkinje fibers pretreated with the class III antiarrhythmic drugs clofilium (10(-7) M) or d,l-sotalol (10(-6) M). Clofilium and d,l-sotalol prolonged action potential duration at 50% and 90% of repolarization without provoking early afterdepolarization (EAD) or delayed afterdepolarization (DAD). Subsequent administration of epinephrine provoked both bradycardia-dependent EADs and tachycardia-dependent DADs in clofilium-treated Purkinje fibers, with predominantly EADs observed in d,l-sotalol-treated Purkinje fibers. A temporary increase in Ca0(+2) from 1.35 mM to 5 mM suppressed both EADs and DADs. The data demonstrate facilitation of epinephrine-induced EADs and DADs by class III antiarrhythmic drugs. The acute suppression of both EADs and DADs observed following an acute increase in Ca0(+2) suggests inward Na(+)-Ca0(+2) exchange current as a basis for both EADs and DADs observed in the presence of class III antiarrhythmic drugs and epinephrine.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Patterson E,Scherlag BJ,Szabo B,Lazzara Rdoi
10.1016/s0022-0736(97)80007-6subject
Has Abstractpub_date
1997-07-01 00:00:00pages
217-24issue
3eissn
0022-0736issn
1532-8430pii
S0022-0736(97)80007-6journal_volume
30pub_type
杂志文章abstract::A 53-year-old patient had a complex ventricular arrhythmia, which most likely was an intermittent pure (nonmodulated) parasystole, due to protection limited to the first part of the cycle coexisting with exit block. However, other interpretations of the observations were possible. Foremost among these was modulated pa...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(97)80046-5
更新日期:1997-10-01 00:00:00
abstract:UNLABELLED:The verapamil-sensitive Belhassen tachycardia is a ventricular reentrant tachycardia, involving left-sided Purkinje fibers and abnormal Purkinje or myocardial tissue. Ablation is feasible, targeting a diastolic fascicular potential in the apical left ventricle. CASE REPORT:We report on a 13-year-old girl wi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2011.02.003
更新日期:2011-11-01 00:00:00
abstract::This article shows the use of the equivalent surface source model in its application to the genesis of the surface ECG in which the sources are of the double layer type. This model has previously been shown to yield an accurate description of body surface potentials during the QRS interval. Its application to the gene...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2001.28896
更新日期:2001-01-01 00:00:00
abstract::Different genetic types of the long QT syndrome (LQTS) are associated with distinct ECG manifestations, which relate to the type and magnitude of ion channel dysfunction. The QTc duration does not differentiate LQTS types, and therefore other static and dynamic ECG parameters reflecting changes in T wave morphology ar...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2006.05.017
更新日期:2006-10-01 00:00:00
abstract::In a 66-year-old male with subacute extensive anterior wall myocardial infarction, we report a change in ST vector orientation from a basal anterior to a mid anterior after coronary artery recanalization of the proximal left anterior descending coronary artery with rotational atherectomy. The ST vector shift on the fr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2009.05.001
更新日期:2009-09-01 00:00:00
abstract::A prolonged QT interval is an important prognostic indicator for cardiac arrhythmias and sudden death. The conventional QT interval measurement, however, includes in its measure the cardiac depolarization (QRS) as well as the cardiac repolarization (JT) intervals. To evaluate the relative contribution of the depolariz...
journal_title:Journal of electrocardiology
pub_type: 临床试验,杂志文章
doi:10.1016/0022-0736(90)90150-z
更新日期:1990-01-01 00:00:00
abstract::Brugada syndrome is characterized by J wave and ST-segment elevation of right precordial leads and causes idiopathic ventricular fibrillation. We experienced a patient of Brugada syndrome with prominent J wave and ST-segment elevation not only in V(1) to V(3) but also in many leads. He suffered spontaneous ventricular...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2004.07.002
更新日期:2004-10-01 00:00:00
abstract::Body surface potential mapping is superior to 12-lead electrocardiogram in detection of acute and old myocardial infarctions. We examined the capability of the ST-T integral and T wave to detect exercise-induced ischemia in body surface potential mapping. Body surface potential mapping with 123 channels was recorded i...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2003.50013
更新日期:2003-04-01 00:00:00
abstract::A 53-year-old man with myocardial infarction was found to have frequent premature ventricular beats. The predominant pattern was classical concealed trigeminy; i.e., the number of conducted sinus beats, S, between extrasystoles satisfied the equation S = 3n + 2, where "n" is zero or any positive integer. Two other tra...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(85)80024-8
更新日期:1985-10-01 00:00:00
abstract:UNLABELLED:PROBLEM PRESENTED: A novel study of catheter ablation of the right pulmonary artery ganglionated plexi (RPA GP) to reduce atrial fibrillation (AF) originating in the pulmonary veins (PVs) is presented. STUDIES UNDERTAKEN:In 20 dogs, atrial effective refractory periods (AERPs), PVERP, and the dispersion of A...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2010.03.007
更新日期:2010-07-01 00:00:00
abstract::We found significant variation within each computer and cardiologist method for measurement of the ECG waveform intervals. Comparison between methods revealed that the HP system had a smaller variability than the MAC or the cardiologist, and that the MAC had a smaller variability than the cardiologist. No variability ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(07)80110-5
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Temporary-permanent pacemakers [TPPM] are externally placed permanent generators attached to active fixation transvenous leads. TPPM can be used as an alternative to standard temporary pacing leads when placement of a permanent pacemaker is contraindicated. We sought to determine the incidence and risk facto...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2016.05.004
更新日期:2016-07-01 00:00:00
abstract::In treating atrial fibrillation (AF) the goal of ventricular rate reduction is still not determined. An animal model of AF was developed in which the relationship between ventricular rate and the parameters of cardiac function in AF can be studied. To simulate AF, complete heart block was chemically produced on open-c...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(05)80100-1
更新日期:1994-04-01 00:00:00
abstract::A three-dimensional heart model was constructed to simulate late potentials and ventricular fibrillation (VF). The model consisted of 50,000 discrete elements having a 1.5-mm spatial resolution. Each element represented excitable ventricular tissue, including a conduction system, and was characterized with classical f...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Simulation of the electrical activation of the heart and its comparison with real in vivo activation is a promising method in testing potential determinants of excitation. Simulation of the electrical activity of the human heart is now emerging as a step forward for understanding and predicting electrophysio...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2008.12.008
更新日期:2009-03-01 00:00:00
abstract::An inexpensive system was developed for automated on-line analysis of ST segment heights, Q, R, and S heights and areas under these peaks, using an LSI-11 microcomputer. System accuracy was evaluated using a computer graphics technique which enabled magnification and labelling of the computed peaks on 60 maps from 17 ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(82)80032-0
更新日期:1982-01-01 00:00:00
abstract::The behavior of the sino-atrial mechanism in isorhythmic dissociation (IRD) was studied in 21 patients, nine with spontaneous IRD and 12 with artificially pacemaker-induced IRD following electrode placement for heart block. Successive P-P, R-R and P-R intervals and blood pressure (BP) fluctuations were determined and ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(77)80052-6
更新日期:1977-04-01 00:00:00
abstract:INTRODUCTION:Not only repolarization, but also depolarization ECG indexes reflect the progression of ischemic injury. The aim was to assess the QRS duration and morphology dynamics during the prolonged coronary occlusion and their association with the myocardial area at risk (MaR) and final infarct size (IS). METHODS:...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2016.03.014
更新日期:2016-05-01 00:00:00
abstract::In recent years, it has become increasingly clear that for an important subset of patients with coronary artery disease, many or all of their ischemic episodes are not accompanied by anginal pain. For these patients, it is desirable to detect these ischemic episodes as periods of ST-segment depression on Holter tapes....
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(10)80019-6
更新日期:1992-01-01 00:00:00
abstract::Thoracic electromaps were recorded before and after sublingual nitroglycerin (NG) in 26 subjects 15 and 30 days after acute myocardial infarction (MI), in order to evaluate the effect of the drug on injury potentials. Ten patients with documented left ventricular aneurysm were also studied 5 to 46 months after acute M...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(81)81007-2
更新日期:1981-10-01 00:00:00
abstract::Traditional electrocardiographic (ECG) and vectorcardiographic (VCG) criteria for left ventricular enlargement (LVE) understandably emphasize the increased tendency of the maximal electrical forces of ventricular depolarization to be directed toward the left. This tendency is manifested on the ECG by increased amplitu...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::Benign Early Repolarization is seen most commonly in young males and is thought to arise from left ventricular hypertrophy, vagal tone and hereditary predilection. This case describes an elderly man with Early Repolarization mimicking acute myocardial infarction after a carotid stent procedure. ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2020.05.002
更新日期:2020-01-01 00:00:00
abstract::As part of an ongoing research protocol, a patient with Wolff-Parkinson-White syndrome underwent body surface potential mapping and electrophysiologic studies before radiofrequency ablation therapy. Careful analysis of the body surface potential mapping data made it possible to distinguish four different map sequences...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(96)80124-5
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND AND AIM:Acute ST-elevation myocardial infarction (STEMI) is associated with fatal and non-fatal ventricular arrhythmic events (VAE). Although primary percutaneous intervention (PCI) is first-line treatment in STEMI, fibrinolytic therapy (FT) is still widely used in many countries. Tp-Te interval; Tp-Te/QT ra...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2019.07.004
更新日期:2019-01-01 00:00:00
abstract::The authors comment on the present status of computerized electro-cardiogram (ECG) works in Japan and demonstrate the preliminary tentative results of CSE (common standards for quantitative electrocardiography) data analysis using the Nagoya program. The more detailed results of the performance of several programs in ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(88)90087-8
更新日期:1988-01-01 00:00:00
abstract::Isomagnetic maps were recorded in normal subjects and in patients with systolic overloading of the right ventricle. The isomagnetic maps examined in this study indicated the instantaneous current source of the heart by applying the "corkscrew rule." The magnetic field recorded by a second derivative gradiometer detect...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(88)80013-x
更新日期:1988-04-01 00:00:00
abstract::Sources of error in averaging for late ventricular potentials include variations in the magnitude and timing of late potentials as well as variability in the temporal alignment of successive cardiac cycles during averaging. Since these errors can both attenuate high frequency signals and add artifactual components to ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::Effects of pirmenol hydrochloride and lidocaine hydrochloride on intraventricular conduction were examined in the infarcted heart of anesthetized dogs. The effects of the drugs on the excitation induced by ventricular stimulations were determined with coupling intervals between 150 and 1,000 ms. Effects of the drugs o...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(91)90020-m
更新日期:1991-10-01 00:00:00
abstract::A retrospective study was conducted to define the incidence of ventricular ectopic beats with exit block (concealed extrasystoles). Of 904 Holter recordings, 92 were admitted for study on the basis of sufficient ventricular ectopic beats on rhythm strips. Concealed bigeminy conforming to the equation of S = 2n - 1 (wh...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(83)80017-x
更新日期:1983-04-01 00:00:00
abstract::A 21year old gentleman was admitted with shortness of breath and heart failure. He was noted to have incessant supraventricular tachycardia which was refractory to pharmacological and electrical cardioversion. Electrophysiology study revealed focal atrial tachycardia from an unusual location which was successfully abl...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2017.09.015
更新日期:2018-01-01 00:00:00