Abstract：
BACKGROUND:Coronary artery disease and myocardial ischemia cause substantial morbidity and mortality. While ischemia is traditionally diagnosed on the 12-lead electrocardiogram (ECG) by shifts in the ST segment, electrical changes are also produced within the QRS complex during depolarization of ischemic ventricular tissue, though these are often of small amplitude and can be missed in traditional ECG analysis. We explore the utility of an easily implemented spectral analysis method for detecting intra-QRS changes during episodes of myocardial ischemia, using Holter recordings from the European ST-T database. METHODS:Time-frequency distributions of QRS complexes from each recording were computed using the continuous wavelet transform. Indices corresponding to frequency content of four overlapping frequency bands were computed: F1 (24-35Hz), F2 (30-45Hz), F3 (40-60Hz), and F4 (50-80Hz). Values of these indices were compared during annotated episodes of ST change and during a baseline during the recording. RESULTS:Marked changes in intra-QRS frequency content were identified during ischemia, grouped by ECG lead analyzed. In lead III, a pronounced and statistically significant increase in the highest frequency sub-bands (F3 and F4) was consistently observed. Analysis of anterior precordial leads also showed significant increases in F4. CONCLUSIONS:Intra-QRS time-frequency analysis using the continuous wavelet transform can identify a spectral signature corresponding to myocardial ischemia in the range 24-80Hz. Intra-QRS spectral analysis has the potential for many clinical applications.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Gramatikov B,Iyer Vdoi
10.1016/j.jelectrocard.2014.09.005subject
Has Abstractpub_date
2015-01-01 00:00:00pages
115-22issue
1eissn
0022-0736issn
1532-8430pii
S0022-0736(14)00353-7journal_volume
48pub_type
杂志文章abstract：:The authors investigated the usefulness of the Karhunen-Loeve technique applied to body surface maps to study regional cardiac excitation. Eigenvectors were derived from the body surface potential maps of 120 healthy adults using the Karhunen-Loeve expansion theory. Then, in the maps of various types of ventricular hy...
journal_title：Journal of electrocardiology
pub_type： 临床试验,杂志文章
doi：10.1016/0022-0736(90)90148-u
更新日期：1990-01-01 00:00:00
abstract：:Frank-lead electrocardiograms (ECGs) were recorded from 59 adult males with suspected coronary artery disease. Three records were recorded consecutively on frequency modulated tape for each patient in (1) supine position, (2) sitting position with arms relaxed, and (3) sitting position on bicycle with arms on bicycle ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(76)80021-0
更新日期：1976-01-01 00:00:00
abstract：:Hypertrophic cardiomyopathy (HCM) have been reported to display impaired heart rate variability, although little is known regarding its prognostic value. By using fast Fourier transformation of 24-hour Holter recordings in 73 HCM patients at a stable clinical condition, we computed 4 spectral components: very low freq...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2003.08.005
更新日期：2003-10-01 00:00:00
abstract：:Under healthy conditions, the normal cardiac (sinus) interbeat interval fluctuates in a complex manner. Quantitative analysis using techniques adapted from statistical physics reveals the presence of long-range power-law correlations extending over thousands of heartbeats. This scale-invariant (fractal) behavior sugge...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(95)80017-4
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:This study is to investigate ventricular repolarization on electrocardiogram (ECG) in a pediatric population receiving methylphenidate (MPH), risperidone (RIS) and combined therapy. METHODS:A total of 215 patients between 6 and 12years with ADHD/conduct disorder receiving methylphenidate, risperidone and ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2017.02.012
更新日期：2017-01-01 00:00:00
abstract：:A 53-year-old man with myocardial infarction was found to have frequent premature ventricular beats. The predominant pattern was classical concealed trigeminy; i.e., the number of conducted sinus beats, S, between extrasystoles satisfied the equation S = 3n + 2, where "n" is zero or any positive integer. Two other tra...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(85)80024-8
更新日期：1985-10-01 00:00:00
abstract：AIMS:Patients with atrioventricular (AV) block can develop left ventricular (LV) dysfunction with long-term right ventricular pacing (RVP). We investigated the role of RVP-induced LV dyssynchrony in this adverse remodeling. METHODS AND RESULTS:Nineteen patients with normal LV function undergoing pacemaker implantation...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2012.04.001
更新日期：2012-07-01 00:00:00
abstract：:Pacemaker capture during the supernormal period was seen in a case of modulated parasystole where ectopic cycles occurred without any interposed nonparasystolic beat. This contrasts with previous clinical reports, since, in the latter, the parasystolic cycle length could not be measured directly. As in experimental st...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(89)90003-4
更新日期：1989-10-01 00:00:00
abstract：AIMS:This investigation addresses procedural characteristics of catheter ablation in patients with atrial fibrillation (AF) and sinus bradycardia. METHODS:From the prospective, multi-center German Ablation Registry 1073 patients with sinus rhythm at the time of AF ablation were divided into two groups according to hea...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jelectrocard.2015.12.007
更新日期：2016-03-01 00:00:00
abstract：UNLABELLED:The verapamil-sensitive Belhassen tachycardia is a ventricular reentrant tachycardia, involving left-sided Purkinje fibers and abnormal Purkinje or myocardial tissue. Ablation is feasible, targeting a diastolic fascicular potential in the apical left ventricle. CASE REPORT:We report on a 13-year-old girl wi...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2011.02.003
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Possible similarities or differences in the ST- and PR-segment deviations in the electrocardiogram of takotsubo cardiomyopathy (TTC) and acute pericarditis (AP) are not well defined. METHODS:We compared different parameters of the admission electrocardiogram in eight patients with TTC and eight patients wit...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2012.11.013
更新日期：2013-03-01 00:00:00
abstract：:The origin of ST depression in ischemia remains poorly understood. The accepted source is of intracellular current flowing between the ischemic and non ischaemic muscle both in systole and diastole such that the AC recorded electrocardiogram shows ST elevation over the ischemic area. The difficulty comes with partial ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2003.09.002
更新日期：2003-01-01 00:00:00
abstract：:We reported a case of Wolff-Parkinson-White syndrome with atrial double potential in coronary sinus (CS) electrograms during paroxysmal supraventricular tachycardia and ventricular pacing. The first component was low in frequency, and its timing was the same as atrial potential recorded by ablation catheter above the ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2007.02.002
更新日期：2007-09-01 00:00:00
abstract：:Takotsubo cardiomyopathy (TTC) is characterized by acute and reversible ventricular dysfunction in the absence of significant coronary artery disease, typically triggered by acute emotional or physical stress. In the acute phase of TTC, the electrocardiogram (ECG) shows ST-segment elevation, which rapidly evolves into...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2013.02.005
更新日期：2013-07-01 00:00:00
abstract：:In patients presenting with signs and symptoms of an acute coronary syndrome (ACS) the combination of multilead ST depression and ST elevation in lead aVR, the electrocardiographic "aVR sign," has been associated with severe left main coronary artery stenosis or diffuse coronary artery disease and a high risk of death...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,评审
doi：10.1016/j.jelectrocard.2019.07.014
更新日期：2019-01-01 00:00:00
abstract：:This study described the linear relationship of the myocardial infarct size, measured postmortem, to the integral of the sequential vector spatial magnitudes analyzed at 400 samples per second during the initial period of abnormal depolarization (IAD) in 25 patients with myocardial infarction (MI) and ten controls. Th...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(82)81002-9
更新日期：1982-10-01 00:00:00
abstract：:Isolated T wave alternans (TWA) could be consistently induced in 13 dogs by infusion of an acid dextrose solution (ACD) and in nine with a 2% EDTA disodium solution. To study the factors concerned in evoking TWA, serial determinations of total and ionized serum calcium (ICa), Mg, K, pH, pCO2 and pO2 were performed. Ar...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(78)80098-3
更新日期：1978-04-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Present methods to extract respiratory myogram interference (RMI) from the Holter-ECG and assess effect of supraventricular arrhythmias (SVAs) onto ECG-based detection of sleep-related breathing disorders (SRBDs) and AHI estimation. METHODS:RMI was quantified as residual energy after ECG cancell...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2014.07.017
更新日期：2014-11-01 00:00:00
abstract：:Sintered Ag-AgCl needle electrodes were used to record unipolar directly coupled (DC) electrograms transmurally from right and left ventricular myocardium. Direct coupling yields unfiltered low-frequency signal content, preserving repolarization waveform morphology. These electrograms were analyzed using completely au...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/0022-0736(88)90102-1
更新日期：1988-08-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation occurs in 20% to 40% of patients post cardiac surgery. Prophylactic amiodarone decreases the incidence of atrial fibrillation, especially in those not taking β-blockers. Studies, however, vary in dosage, duration of treatment, and route of administration. Limited studies evaluating short ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jelectrocard.2012.07.005
更新日期：2012-11-01 00:00:00
abstract：INTRODUCTION:The right ventricular myocardial infarction (RVMI) has traditionally been mainly related to inferior wall ST elevation myocardial infarction (STEMI). This study assessed the RVMI electrocardiographic (ECG-RVMI) signs in relationship to ECG-based STEMI localization and to the infarct related artery in patie...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2016.08.001
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:QRS-duration predicts mortality in patients with heart failure and, to a lesser extent, the general population. However, in patients with diabetes, its prognostic significance is unknown. To better understand how QRS-duration relates to mortality among those with diabetes, we explored survival as a function ...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2019.11.053
更新日期：2020-01-01 00:00:00
abstract：:We have developed a computer program which simulates a paced cardiac rhythm strip, graphically generating the electrocardiogram (ECG) on a color monitor. Any pacemaker, programmed as desired, dynamically interacts with a preselected intrinsic rhythm. Utilizing symbols prevalent in the pacing industry, this graphics-or...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：BACKGROUND:Most patients presenting with suspected acute coronary syndrome (ACS) are admitted to telemetry units. While telemetry is an appropriate level of care, acute complications requiring a higher level of care in the intensive care unit (ICU) occur. PURPOSE:Among patients admitted to telemetry for suspected ACS,...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2016.08.010
更新日期：2016-01-01 00:00:00
abstract：:The purpose of this experiment is to study the possibility of intra-QRS high-frequency electrocardiographic (HFECG) changes for the evaluation of and recovery from myocardial ischemia in both the time-domain and spectral-turbulence analyses on the signal-averaged ECG using the Holter ECG monitoring (Holter SAECG) syst...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(95)80064-6
更新日期：1995-01-01 00:00:00
abstract：:Time course evolution of R, Q, T and ST components of the electrocardiogram during the first 12 hours of an acute myocardial infarction was studied. A comparison between anterior-extensive and anteroseptal wall infarctions (anterior group), and inferior-extensive and inferior wall infarction (inferior group) showed ap...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(87)80098-5
更新日期：1987-04-01 00:00:00
abstract：:Computer analysis of electrocardiograms (ECGs) provides a large amount of ECG measurement data, which may be used for diagnostic classification and storage in ECG databases. Until now, neither error limits for ECG measurements have been specified nor has their influence on diagnostic statements been systematically inv...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(96)80022-7
更新日期：1996-01-01 00:00:00
abstract：:In a 66-year-old male with subacute extensive anterior wall myocardial infarction, we report a change in ST vector orientation from a basal anterior to a mid anterior after coronary artery recanalization of the proximal left anterior descending coronary artery with rotational atherectomy. The ST vector shift on the fr...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/j.jelectrocard.2009.05.001
更新日期：2009-09-01 00:00:00
abstract：:An analytical study was performed to estimate the magnitude of the visual Q wave duration bias produced by pressurized ink round stylus electrocardiographic (ECG) recorders. With a paper speed of 25 mm/sec and the ECG tracing width of 0.25 mm, the visually measured Q waves are on the average 8 msec too short. The corr...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(78)80137-x
更新日期：1978-10-01 00:00:00
abstract：:The ability of ECG-VCG to predict the severity of postinfarction LV asynergy was evaluated in 152 patients with previous myocardial infarction who underwent left cineventriculography in the right anterior oblique view. Various ECG and VCG signs were examined in order to predict the existence of severe asynergy in gene...
journal_title：Journal of electrocardiology
pub_type： 杂志文章
doi：10.1016/s0022-0736(84)81092-4
更新日期：1984-04-01 00:00:00
