Abstract:
:Prognosis and risk factors for patients age 35years or younger with Brugada syndrome (BrS) were prospectively explored in a sub-analysis of the Japan Idiopathic Ventricular Fibrillation Study (J-IVFS) registry. During the period from February 2002 to January 2011, 69 cases (mean age 30±6years, male=66) of the young (at or less than 35years old) BrS were enrolled in J-IVFS and the clinical course was followed for more than 1year. They were divided into 3 groups: documented ventricular fibrillation (VF) or aborted sudden cardiac death (SCD) (VF group, 12 cases), syncope without documentation of VF (Syncope group, 17 cases) and asymptomatic group (Asympt. group, 40 cases). During a mean follow-up period of 43±27months, cardiac events (VF and/or SCD) developed in 8 cases, with 5 of 12 cases in the VF (41.7%), 2 of 17 cases in the Syncope (11.8%) and 1 of 40 cases in the Asympt. group (2.5%). The VF group had a worse prognosis for cardiac events than the Syncope and Asympt. group. Multivariate analysis revealed symptoms as a risk factor for predicting cardiac events.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Hiraoka M,Takagi M,Yokoyama Y,Sekiguchi Y,Aihara N,Aonuma K,Japan Idiopathic Ventricular Fibrillation Study Investigators.doi
10.1016/j.jelectrocard.2013.04.003subject
Has Abstractpub_date
2013-07-01 00:00:00pages
279-83issue
4eissn
0022-0736issn
1532-8430pii
S0022-0736(13)00119-2journal_volume
46pub_type
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journal_title:Journal of electrocardiology
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